HO-1 and CO: Fighters vs sickle cell disease?

Blood

Volumn 122, Issue 15, 2013, Pages 2535-2536

  Araujo, Jesus A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; CARBON MONOXIDE; GLUTAMIC ACID; HEME OXYGENASE 1; HEMOGLOBIN BETA CHAIN; HEMOGLOBIN S; HYDROXYUREA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PADGEM PROTEIN; PROTOPORPHYRIN TIN; REACTIVE OXYGEN METABOLITE; THYMINE; TRANSCRIPTION FACTOR NRF2; VALINE; VON WILLEBRAND FACTOR;

AMINO ACID SUBSTITUTION; ATHEROSCLEROSIS; CARDIOPULMONARY INSUFFICIENCY; CELL ADHESION; CELL NUCLEUS; CODON; DEOXYGENATION; ENZYME ACTIVITY; ENZYME INHIBITION; HEMOGLOBINOPATHY; HETEROZYGOSITY; HUMAN; HYDROPHILICITY; HYDROPHOBICITY; INTRAVASCULAR HEMOLYSIS; LIFE EXPECTANCY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN POLYMERIZATION; REOXYGENATION; SHORT SURVEY; SICKLE CELL ANEMIA; STEM CELL TRANSPLANTATION; TRANSPOSON; UPREGULATION; VASOCONSTRICTION;

EID: 84888247581     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-08-521922     Document Type: Short Survey

References (10)

1. Belcher JD, Young M, Chen C, et al. MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-ocllusion in transgenic sickle mice. Blood. 2013;122(15):2757-2764.
2. Sheth S, Licursi M, Bhatia M. Sickle cell disease: time for a closer look at treatment options? Br J Haematol. 2013;162(4):455-464.
3. Belcher JD, Mahaseth H, Welch TE, Otterbein LE, Hebbel RP, Vercellotti GM. Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. J Clin Invest. 2006;116(3):808-816.
4. Stuart MJ, Nagel RL. Sickle-cell disease. Lancet. 2004;364(9442):1343- 1360.
5. Sultana C, Shen Y, Rattan V, Johnson C, Kalra VK. Interaction of sickle erythrocytes with endothelial cells in the presence of endothelial cell conditioned medium induces oxidant stress leading to transendothelial migration of monocytes. Blood. 1998;92(10):3924-3935.
6. Araujo JA, Zhang M, Yin F. Heme oxygenase-1, oxidation, inflammation, and atherosclerosis. Front Pharmacol. 2012;3:119.
7. Kim KM, Pae HO, Zheng M, Park R, Kim YM, Chung HT. Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress. Circ Res. 2007;101(9):919-927.
8. Belcher JD, Vineyard JV, Bruzzone CM, et al. Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease. J Mol Med (Berl). 2010;88(7):665-675.
9. Barajas B, Che N, Yin F, et al. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arterioscler Thromb Vasc Biol. 2011;31(1):58-66.
10. Gorman D, Drewry A, Huang YL, Sames C. The clinical toxicology of carbon monoxide. Toxicology. 2003;187(1):25-38.