-
1
-
-
77952248366
-
Epidemiology and risk factors for kidney cancer
-
doi:10.1038/nrurol.2010.46
-
Chow WH, Dong LM, Devesa SS. Epidemiology and risk factors for kidney cancer. Nat Rev Urol (2010) 7:245-57. doi:10.1038/nrurol.2010.46
-
(2010)
Nat Rev Urol
, vol.7
, pp. 245-257
-
-
Chow, W.H.1
Dong, L.M.2
Devesa, S.S.3
-
2
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
doi:10.1002/ijc.25516
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer (2010) 127:2893-917. doi:10.1002/ijc.25516
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
4
-
-
2142853538
-
Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma
-
doi:10.1007/BF02524349
-
Beck SD, Patel MI, Snyder ME, Kattan MW, Motzer RJ, Reuter VE, et al. Effect of papillary and chromophobe cell type on disease-free survival after nephrectomy for renal cell carcinoma. Ann Surg Oncol (2004) 11:71-7. doi:10.1007/BF02524349
-
(2004)
Ann Surg Oncol
, vol.11
, pp. 71-77
-
-
Beck, S.D.1
Patel, M.I.2
Snyder, M.E.3
Kattan, M.W.4
Motzer, R.J.5
Reuter, V.E.6
-
5
-
-
0027273479
-
Cytotoxic chemotherapy for advanced renal cell carcinoma
-
Yagoda A, Petrylak D, Thompson S. Cytotoxic chemotherapy for advanced renal cell carcinoma. Urol Clin North Am (1993) 20:303-21.
-
(1993)
Urol Clin North Am
, vol.20
, pp. 303-321
-
-
Yagoda, A.1
Petrylak, D.2
Thompson, S.3
-
6
-
-
12344335787
-
Renal cell carcinoma: review of novel single-agent therapeutics and combination regimens
-
doi:10.1093/annonc/mdi002
-
Amato RJ. Renal cell carcinoma: review of novel single-agent therapeutics and combination regimens. Ann Oncol (2005) 16:7-15. doi:10.1093/annonc/mdi002
-
(2005)
Ann Oncol
, vol.16
, pp. 7-15
-
-
Amato, R.J.1
-
7
-
-
34247260551
-
Immunotherapy for renal cell cancer
-
doi:10.1200/JCO.2006.08.3774
-
Yang JC, Childs R. Immunotherapy for renal cell cancer. J Clin Oncol (2006) 24:5576-83. doi:10.1200/JCO.2006.08.3774
-
(2006)
J Clin Oncol
, vol.24
, pp. 5576-5583
-
-
Yang, J.C.1
Childs, R.2
-
8
-
-
46749085802
-
An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial
-
doi:10.1016/S0140-6736(08)60697-2
-
Wood C, Srivastava P, Bukowski R, Lacombe L, Gorelov AI, Gorelov S, et al. An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial. Lancet (2008) 372:145-54. doi:10.1016/S0140-6736(08)60697-2
-
(2008)
Lancet
, vol.372
, pp. 145-154
-
-
Wood, C.1
Srivastava, P.2
Bukowski, R.3
Lacombe, L.4
Gorelov, A.I.5
Gorelov, S.6
-
9
-
-
46749131796
-
Vitespen: a vaccine for renal cancer?
-
doi:10.1016/S0140-6736(08)60698-4
-
Yang JC. Vitespen: a vaccine for renal cancer? Lancet (2008) 372:92-3. doi:10.1016/S0140-6736(08)60698-4
-
(2008)
Lancet
, vol.372
, pp. 92-93
-
-
Yang, J.C.1
-
10
-
-
84861112043
-
Systemic therapy in renal cell carcinoma: advancing paradigms
-
Posadas EM, Figlin RA. Systemic therapy in renal cell carcinoma: advancing paradigms. Oncology (Williston Park) (2012) 26:290-301.
-
(2012)
Oncology (Williston Park)
, vol.26
, pp. 290-301
-
-
Posadas, E.M.1
Figlin, R.A.2
-
11
-
-
0032772880
-
Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
-
Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol (1999) 17:2530-40.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2530-2540
-
-
Motzer, R.J.1
Mazumdar, M.2
Bacik, J.3
Berg, W.4
Amsterdam, A.5
Ferrara, J.6
-
12
-
-
14144252047
-
Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma
-
doi:10.1200/JCO.2005.05.179
-
Mekhail TM, Abou-Jawde RM, Boumerhi G, Malhi S, Wood L, Elson P, et al. Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma. J Clin Oncol (2005) 23:832-41. doi:10.1200/JCO.2005.05.179
-
(2005)
J Clin Oncol
, vol.23
, pp. 832-841
-
-
Mekhail, T.M.1
Abou-Jawde, R.M.2
Boumerhi, G.3
Malhi, S.4
Wood, L.5
Elson, P.6
-
13
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
doi:10.1200/JCO.2008.20.1293
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol (2009) 27:3584-90. doi:10.1200/JCO.2008.20.1293
-
(2009)
J Clin Oncol
, vol.27
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Oudard, S.6
-
14
-
-
33750732283
-
Recombinant viral vectors: cancer vaccines
-
doi:10.1016/j.addr.2006.05.005
-
Harrop R, John J, Carroll MW. Recombinant viral vectors: cancer vaccines. Adv Drug Deliv Rev (2006) 58:931-47. doi:10.1016/j.addr.2006.05.005
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 931-947
-
-
Harrop, R.1
John, J.2
Carroll, M.W.3
-
15
-
-
32944473827
-
Viral vectors for cancer immunotherapy
-
doi:10.2741/1838
-
Harrop R, Carroll MW. Viral vectors for cancer immunotherapy. Front Biosci (2006) 11:804-17. doi:10.2741/1838
-
(2006)
Front Biosci
, vol.11
, pp. 804-817
-
-
Harrop, R.1
Carroll, M.W.2
-
16
-
-
0029643982
-
Genetic instability and tumor cell variation: implications for immunotherapy
-
doi:10.1093/jnci/87.4.241
-
Fenton RG, Longo DL. Genetic instability and tumor cell variation: implications for immunotherapy. J Natl Cancer Inst (1995) 87:241-3. doi:10.1093/jnci/87.4.241
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 241-243
-
-
Fenton, R.G.1
Longo, D.L.2
-
17
-
-
0036677372
-
Glycosylation defining cancer malignancy: new wine in an old bottle
-
doi:10.1073/pnas.172380699
-
Hakomori S. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci U S A (2002) 99:10231-3. doi:10.1073/pnas.172380699
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10231-10233
-
-
Hakomori, S.1
-
18
-
-
1842562212
-
Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance
-
doi:10.1200/JCO.2004.10.041
-
Mapara MY, Sykes M. Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J Clin Oncol (2004) 22:1136-51. doi:10.1200/JCO.2004.10.041
-
(2004)
J Clin Oncol
, vol.22
, pp. 1136-1151
-
-
Mapara, M.Y.1
Sykes, M.2
-
19
-
-
9244248089
-
Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential?
-
doi:10.1016/j.copbio.2004.09.001
-
Drexler I, Staib C, Sutter G. Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential? Curr Opin Biotechnol (2004) 15:506-12. doi:10.1016/j.copbio.2004.09.001
-
(2004)
Curr Opin Biotechnol
, vol.15
, pp. 506-512
-
-
Drexler, I.1
Staib, C.2
Sutter, G.3
-
20
-
-
84858294842
-
Biosafety aspects of modified vaccinia virus Ankara (MVA)-based vectors used for gene therapy or vaccination
-
doi:10.1016/j
-
Verheust C, Goossens M, Pauwels K, Breyer D. Biosafety aspects of modified vaccinia virus Ankara (MVA)-based vectors used for gene therapy or vaccination. Vaccine (2012) 30:2623-32. doi:10.1016/j
-
(2012)
Vaccine
, vol.30
, pp. 2623-2632
-
-
Verheust, C.1
Goossens, M.2
Pauwels, K.3
Breyer, D.4
-
21
-
-
0025060715
-
Isolation and characterization of 5T4, a tumour-associated antigen
-
doi:10.1002/ijc.2910450132
-
Hole N, Stern PL. Isolation and characterization of 5T4, a tumour-associated antigen. Int J Cancer (1990) 45:179-84. doi:10.1002/ijc.2910450132
-
(1990)
Int J Cancer
, vol.45
, pp. 179-184
-
-
Hole, N.1
Stern, P.L.2
-
22
-
-
0025109257
-
Immunohistological distribution of 5T4 antigen in normal and malignant tissues
-
doi:10.1038/bjc.1990.20
-
Southall PJ, Boxer GM, Bagshawe KD, Hole N, Bromley M, Stern PL. Immunohistological distribution of 5T4 antigen in normal and malignant tissues. Br J Cancer (1990) 61:89-95. doi:10.1038/bjc.1990.20
-
(1990)
Br J Cancer
, vol.61
, pp. 89-95
-
-
Southall, P.J.1
Boxer, G.M.2
Bagshawe, K.D.3
Hole, N.4
Bromley, M.5
Stern, P.L.6
-
23
-
-
0028324131
-
Prognostic significance of 5T4 oncofetal antigen expression in colorectal carcinoma
-
doi:10.1038/bjc.1994.173
-
Starzynska T, Marsh PJ, Schofield PF, Roberts SA, Myers KA, Stern PL. Prognostic significance of 5T4 oncofetal antigen expression in colorectal carcinoma. Br J Cancer (1994) 69:899-902. doi:10.1038/bjc.1994.173
-
(1994)
Br J Cancer
, vol.69
, pp. 899-902
-
-
Starzynska, T.1
Marsh, P.J.2
Schofield, P.F.3
Roberts, S.A.4
Myers, K.A.5
Stern, P.L.6
-
24
-
-
27144440353
-
Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy
-
doi:10.1038/sj.bjc.6602776
-
Griffiths RW, Gilham DE, Dangoor A, Ramani V, Clarke NW, Stern PL, et al. Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy. Br J Cancer (2005) 93:670-7. doi:10.1038/sj.bjc.6602776
-
(2005)
Br J Cancer
, vol.93
, pp. 670-677
-
-
Griffiths, R.W.1
Gilham, D.E.2
Dangoor, A.3
Ramani, V.4
Clarke, N.W.5
Stern, P.L.6
-
25
-
-
22244468657
-
Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia
-
doi:10.1002/dvdy.20482
-
Barrow KM, Ward CM, Rutter J, Ali S, Stern PL. Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia. Dev Dyn (2005) 233:1535-45. doi:10.1002/dvdy.20482
-
(2005)
Dev Dyn
, vol.233
, pp. 1535-1545
-
-
Barrow, K.M.1
Ward, C.M.2
Rutter, J.3
Ali, S.4
Stern, P.L.5
-
26
-
-
0032980503
-
Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes
-
doi:10.1073/pnas.96.6.2982
-
Overwijk WW, Lee DS, Surman DR, Irvine KR, Touloukian CE, Chan CC, et al. Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes. Proc Natl Acad Sci U S A (1999) 96:2982-7. doi:10.1073/pnas.96.6.2982
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2982-2987
-
-
Overwijk, W.W.1
Lee, D.S.2
Surman, D.R.3
Irvine, K.R.4
Touloukian, C.E.5
Chan, C.C.6
-
27
-
-
0036897080
-
Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity
-
Greiner JW, Zeytin H, Anver MR, Schlom J. Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity. Cancer Res (2002) 62:6944-51.
-
(2002)
Cancer Res
, vol.62
, pp. 6944-6951
-
-
Greiner, J.W.1
Zeytin, H.2
Anver, M.R.3
Schlom, J.4
-
28
-
-
0036535461
-
Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen
-
doi:10.1042/0264-6021:3630137
-
Shaw DM, Woods AM, Myers KA, Westwater C, Rahi-Saund V, Davies MJ, et al. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen. Biochem J (2002) 363:137-45. doi:10.1042/0264-6021:3630137
-
(2002)
Biochem J
, vol.363
, pp. 137-145
-
-
Shaw, D.M.1
Woods, A.M.2
Myers, K.A.3
Westwater, C.4
Rahi-Saund, V.5
Davies, M.J.6
-
29
-
-
0028340558
-
Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats
-
Myers KA, Rahi-Saund V, Davison MD, Young JA, Cheater AJ, Stern PL. Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats. J Biol Chem (1994) 269:9319-24.
-
(1994)
J Biol Chem
, vol.269
, pp. 9319-9324
-
-
Myers, K.A.1
Rahi-Saund, V.2
Davison, M.D.3
Young, J.A.4
Cheater, A.J.5
Stern, P.L.6
-
30
-
-
0023818391
-
A 72 kD trophoblast glycoprotein defined by a monoclonal antibody
-
doi:10.1038/bjc.1988.53
-
Hole N, Stern PL. A 72 kD trophoblast glycoprotein defined by a monoclonal antibody. Br J Cancer (1988) 57:239-46. doi:10.1038/bjc.1988.53
-
(1988)
Br J Cancer
, vol.57
, pp. 239-246
-
-
Hole, N.1
Stern, P.L.2
-
31
-
-
0029903794
-
Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells
-
doi:10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6
-
Carsberg CJ, Myers KA, Stern PL. Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells. Int J Cancer (1996) 68:84-92. doi:10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6
-
(1996)
Int J Cancer
, vol.68
, pp. 84-92
-
-
Carsberg, C.J.1
Myers, K.A.2
Stern, P.L.3
-
32
-
-
0025060861
-
Investigation of expression of 5T4 antigen in cervical cancer
-
doi:10.1038/bjc.1990.21
-
Jones H, Roberts G, Hole N, McDicken IW, Stern P. Investigation of expression of 5T4 antigen in cervical cancer. Br J Cancer (1990) 61:96-100. doi:10.1038/bjc.1990.21
-
(1990)
Br J Cancer
, vol.61
, pp. 96-100
-
-
Jones, H.1
Roberts, G.2
Hole, N.3
McDicken, I.W.4
Stern, P.5
-
33
-
-
0031781449
-
5T4 oncofetal antigen in gastric carcinoma and its clinical significance
-
doi:10.1097/00042737-199806000-00008
-
Starzynska T, Wiechowska-Kozlowska A, Marlicz K, Bromley M, Roberts SA, Lawniczak M, et al. 5T4 oncofetal antigen in gastric carcinoma and its clinical significance. Eur J Gastroenterol Hepatol (1998) 10:479-84. doi:10.1097/00042737-199806000-00008
-
(1998)
Eur J Gastroenterol Hepatol
, vol.10
, pp. 479-484
-
-
Starzynska, T.1
Wiechowska-Kozlowska, A.2
Marlicz, K.3
Bromley, M.4
Roberts, S.A.5
Lawniczak, M.6
-
34
-
-
0029025707
-
5T4 oncofetal antigen expression in ovarian carcinoma
-
doi:10.1046/j.1525-1438.1995.05040269.x
-
Wrigley E, McGown AT, Rennison J, Swindell R, Crowther D, Starzynska T, et al. 5T4 oncofetal antigen expression in ovarian carcinoma. Int J Gynecol Cancer (1995) 5:269-74. doi:10.1046/j.1525-1438.1995.05040269.x
-
(1995)
Int J Gynecol Cancer
, vol.5
, pp. 269-274
-
-
Wrigley, E.1
McGown, A.T.2
Rennison, J.3
Swindell, R.4
Crowther, D.5
Starzynska, T.6
-
35
-
-
0026442540
-
The expression of 5T4 antigen in colorectal and gastric carcinoma
-
doi:10.1038/bjc.1992.375
-
Starzynska T, Rahi V, Stern PL. The expression of 5T4 antigen in colorectal and gastric carcinoma. Br J Cancer (1992) 66:867-9. doi:10.1038/bjc.1992.375
-
(1992)
Br J Cancer
, vol.66
, pp. 867-869
-
-
Starzynska, T.1
Rahi, V.2
Stern, P.L.3
-
36
-
-
0031004055
-
Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: a murine tumor model
-
doi:10.1016/S0264-410X(96)00195-8
-
Carroll MW, Overwijk WW, Chamberlain RS, Rosenberg SA, Moss B, Restifo NP. Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: a murine tumor model. Vaccine (1997) 15:387-94. doi:10.1016/S0264-410X(96)00195-8
-
(1997)
Vaccine
, vol.15
, pp. 387-394
-
-
Carroll, M.W.1
Overwijk, W.W.2
Chamberlain, R.S.3
Rosenberg, S.A.4
Moss, B.5
Restifo, N.P.6
-
37
-
-
0026442276
-
Nonreplicating vaccinia vector efficiently expresses recombinant genes
-
doi:10.1073/pnas.89.22.10847
-
Sutter G, Moss B. Nonreplicating vaccinia vector efficiently expresses recombinant genes. Proc Natl Acad Sci U S A (1992) 89:10847-51. doi:10.1073/pnas.89.22.10847
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10847-10851
-
-
Sutter, G.1
Moss, B.2
-
38
-
-
0021082628
-
Infectious poxvirus vectors have capacity for at least 25 000 base pairs of foreign DNA
-
doi:10.1016/0378-1119(83)90163-4
-
Smith GL, Moss B. Infectious poxvirus vectors have capacity for at least 25 000 base pairs of foreign DNA. Gene (1983) 25:21-8. doi:10.1016/0378-1119(83)90163-4
-
(1983)
Gene
, vol.25
, pp. 21-28
-
-
Smith, G.L.1
Moss, B.2
-
39
-
-
1842848097
-
Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors
-
Mulryan K, Ryan MG, Myers KA, Shaw D, Wang W, Kingsman SM, et al. Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors. Mol Cancer Ther (2002) 1:1129-37.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1129-1137
-
-
Mulryan, K.1
Ryan, M.G.2
Myers, K.A.3
Shaw, D.4
Wang, W.5
Kingsman, S.M.6
-
40
-
-
33745223435
-
Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial
-
doi:10.1158/1078-0432.CCR-05-2732
-
Harrop R, Connolly N, Redchenko I, Valle J, Saunders M, Ryan MG, et al. Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial. Clin Cancer Res (2006) 12:3416-24. doi:10.1158/1078-0432.CCR-05-2732
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3416-3424
-
-
Harrop, R.1
Connolly, N.2
Redchenko, I.3
Valle, J.4
Saunders, M.5
Ryan, M.G.6
-
41
-
-
67650136139
-
An MVA-based vaccine targeting the oncofetal antigen 5T4 in patients undergoing surgical resection of colorectal cancer liver metastases
-
doi:10.1097/CJI.0b013e3181876ab3
-
Elkord E, Dangoor A, Drury NL, Harrop R, Burt DJ, Drijfhout JW, et al. An MVA-based vaccine targeting the oncofetal antigen 5T4 in patients undergoing surgical resection of colorectal cancer liver metastases. J Immunother (2008) 31:820-9. doi:10.1097/CJI.0b013e3181876ab3
-
(2008)
J Immunother
, vol.31
, pp. 820-829
-
-
Elkord, E.1
Dangoor, A.2
Drury, N.L.3
Harrop, R.4
Burt, D.J.5
Drijfhout, J.W.6
-
42
-
-
34547652648
-
Vaccination of colorectal cancer patients with modified vaccinia ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses
-
doi:10.1158/1078-0432.CCR-07-0704
-
Harrop R, Drury N, Shingler W, Chikoti P, Redchenko I, Carroll MW, et al. Vaccination of colorectal cancer patients with modified vaccinia ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses. Clin Cancer Res (2007) 13:4487-94. doi:10.1158/1078-0432.CCR-07-0704
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4487-4494
-
-
Harrop, R.1
Drury, N.2
Shingler, W.3
Chikoti, P.4
Redchenko, I.5
Carroll, M.W.6
-
43
-
-
42649138944
-
Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses
-
doi:10.1007/s00262-007-0428-7
-
Harrop R, Drury N, Shingler W, Chikoti P, Redchenko I, Carroll MW, et al. Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses. Cancer Immunol Immunother (2008) 57:977-86. doi:10.1007/s00262-007-0428-7
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 977-986
-
-
Harrop, R.1
Drury, N.2
Shingler, W.3
Chikoti, P.4
Redchenko, I.5
Carroll, M.W.6
-
44
-
-
48549088424
-
Vaccination of prostate cancer patients with modified vaccinia ankara delivering the tumor antigen 5T4 (TroVax): a phase 2 trial
-
doi:10.1097/CJI.0b013e31817deafd
-
Amato RJ, Drury N, Naylor S, Jac J, Saxena S, Cao A, et al. Vaccination of prostate cancer patients with modified vaccinia ankara delivering the tumor antigen 5T4 (TroVax): a phase 2 trial. J Immunother (2008) 31:577-85. doi:10.1097/CJI.0b013e31817deafd
-
(2008)
J Immunother
, vol.31
, pp. 577-585
-
-
Amato, R.J.1
Drury, N.2
Naylor, S.3
Jac, J.4
Saxena, S.5
Cao, A.6
-
45
-
-
67449085969
-
Vaccination of patients with metastatic renal cancer with modified vaccinia Ankara encoding the tumor antigen 5T4 (TroVax) given alongside interferon-alpha
-
doi:10.1097/CJI.0b013e31819d297e
-
Hawkins RE, MacDermott C, Shablak A, Hamer C, Thistlethwaite F, Drury NL, et al. Vaccination of patients with metastatic renal cancer with modified vaccinia Ankara encoding the tumor antigen 5T4 (TroVax) given alongside interferon-alpha. J Immunother (2009) 32:424-9. doi:10.1097/CJI.0b013e31819d297e
-
(2009)
J Immunother
, vol.32
, pp. 424-429
-
-
Hawkins, R.E.1
MacDermott, C.2
Shablak, A.3
Hamer, C.4
Thistlethwaite, F.5
Drury, N.L.6
-
46
-
-
58149354757
-
Vaccination of renal cell cancer patients with modified vaccinia ankara delivering tumor antigen 5T4 (TroVax) administered with interleukin 2: a phase II trial
-
doi:10.1158/1078-0432.CCR-08-0668
-
Amato RJ, Shingler W, Naylor S, Jac J, Willis J, Saxena S, et al. Vaccination of renal cell cancer patients with modified vaccinia ankara delivering tumor antigen 5T4 (TroVax) administered with interleukin 2: a phase II trial. Clin Cancer Res (2008) 14:7504-10. doi:10.1158/1078-0432.CCR-08-0668
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7504-7510
-
-
Amato, R.J.1
Shingler, W.2
Naylor, S.3
Jac, J.4
Willis, J.5
Saxena, S.6
-
47
-
-
60549106426
-
Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma
-
doi:10.1186/1479-5876-7-2
-
Kaufman HL, Taback B, Sherman W, Kim DW, Shingler WH, Moroziewicz D, et al. Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma. J Transl Med (2009) 7:2. doi:10.1186/1479-5876-7-2
-
(2009)
J Transl Med
, vol.7
, pp. 2
-
-
Kaufman, H.L.1
Taback, B.2
Sherman, W.3
Kim, D.W.4
Shingler, W.H.5
Moroziewicz, D.6
-
48
-
-
68449100522
-
Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) alone or administered in combination with interferon-alpha (IFN-alpha): a phase 2 trial
-
doi:10.1097/CJI.0b013e3181ace876
-
Amato RJ, Shingler W, Goonewardena M, de Belin J, Naylor S, Jac J, et al. Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) alone or administered in combination with interferon-alpha (IFN-alpha): a phase 2 trial. J Immunother (2009) 32:765-72. doi:10.1097/CJI.0b013e3181ace876
-
(2009)
J Immunother
, vol.32
, pp. 765-772
-
-
Amato, R.J.1
Shingler, W.2
Goonewardena, M.3
de Belin, J.4
Naylor, S.5
Jac, J.6
-
49
-
-
78349284842
-
Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study
-
doi:10.1158/1078-0432.CCR-10-2082
-
Amato RJ, Hawkins RE, Kaufman HL, Thompson JA, Tomczak P, Szczylik C, et al. Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study. Clin Cancer Res (2010) 16:5539-47. doi:10.1158/1078-0432.CCR-10-2082
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5539-5547
-
-
Amato, R.J.1
Hawkins, R.E.2
Kaufman, H.L.3
Thompson, J.A.4
Tomczak, P.5
Szczylik, C.6
-
50
-
-
84871004671
-
Analysis of pre-treatment markers predictive of treatment benefit for the therapeutic cancer vaccine MVA-5T4 (TroVax)
-
doi:10.1007/s00262-012-1302-9
-
Harrop R, Treasure P, de Belin J, Kelleher M, Bolton G, Naylor S, et al. Analysis of pre-treatment markers predictive of treatment benefit for the therapeutic cancer vaccine MVA-5T4 (TroVax). Cancer Immunol Immunother (2012) 61:2283-94. doi:10.1007/s00262-012-1302-9
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 2283-2294
-
-
Harrop, R.1
Treasure, P.2
de Belin, J.3
Kelleher, M.4
Bolton, G.5
Naylor, S.6
-
51
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria
-
doi:10.1158/1078-0432.CCR-09-1624
-
Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbe C, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res (2009) 15:7412-20. doi:10.1158/1078-0432.CCR-09-1624
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O'Day, S.3
Weber, J.S.4
Hamid, O.5
Lebbe, C.6
-
52
-
-
0027500568
-
Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow
-
doi:10.1073/pnas.90.7.3038
-
Inaba K, Inaba M, Deguchi M, Hagi K, Yasumizu R, Ikehara S, et al. Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow. Proc Natl Acad Sci U S A (1993) 90:3038-42. doi:10.1073/pnas.90.7.3038
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 3038-3042
-
-
Inaba, K.1
Inaba, M.2
Deguchi, M.3
Hagi, K.4
Yasumizu, R.5
Ikehara, S.6
-
53
-
-
32644479365
-
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know
-
doi:10.1038/sj.cr.7310017
-
Shi Y, Liu CH, Roberts AI, Das J, Xu G, Ren G, et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res (2006) 16:126-33. doi:10.1038/sj.cr.7310017
-
(2006)
Cell Res
, vol.16
, pp. 126-133
-
-
Shi, Y.1
Liu, C.H.2
Roberts, A.I.3
Das, J.4
Xu, G.5
Ren, G.6
-
54
-
-
0033998594
-
Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor
-
Spitler LE, Grossbard ML, Ernstoff MS, Silver G, Jacobs M, Hayes FA, et al. Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor. J Clin Oncol (2000) 18:1614-21.
-
(2000)
J Clin Oncol
, vol.18
, pp. 1614-1621
-
-
Spitler, L.E.1
Grossbard, M.L.2
Ernstoff, M.S.3
Silver, G.4
Jacobs, M.5
Hayes, F.A.6
-
55
-
-
33750743386
-
Immune escape for renal cell carcinoma: CD70 mediates apoptosis in lymphocytes
-
doi:10.1593/neo.06451
-
Diegmann J, Junker K, Loncarevic IF, Michel S, Schimmel B, von Eggeling F. Immune escape for renal cell carcinoma: CD70 mediates apoptosis in lymphocytes. Neoplasia (2006) 8:933-8. doi:10.1593/neo.06451
-
(2006)
Neoplasia
, vol.8
, pp. 933-938
-
-
Diegmann, J.1
Junker, K.2
Loncarevic, I.F.3
Michel, S.4
Schimmel, B.5
von Eggeling, F.6
-
56
-
-
0032927310
-
Mechanisms of apoptosis in T cells from patients with renal cell carcinoma
-
Uzzo RG, Rayman P, Kolenko V, Clark PE, Bloom T, Ward AM, et al. Mechanisms of apoptosis in T cells from patients with renal cell carcinoma. Clin Cancer Res (1999) 5:1219-29.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1219-1229
-
-
Uzzo, R.G.1
Rayman, P.2
Kolenko, V.3
Clark, P.E.4
Bloom, T.5
Ward, A.M.6
-
57
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 155:1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
58
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity
-
Shimizu J, Yamazaki S, Sakaguchi S. Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol (1999) 163:5211-8.
-
(1999)
J Immunol
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
59
-
-
15944410592
-
Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
-
doi:10.1182/blood-2004-06-2410
-
Lutsiak ME, Semnani RT, De Pascalis R, Kashmiri SV, Schlom J, Sabzevari H. Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood (2005) 105:2862-8. doi:10.1182/blood-2004-06-2410
-
(2005)
Blood
, vol.105
, pp. 2862-2868
-
-
Lutsiak, M.E.1
Semnani, R.T.2
De Pascalis, R.3
Kashmiri, S.V.4
Schlom, J.5
Sabzevari, H.6
-
60
-
-
79952280877
-
Sunitinib and other targeted therapies for renal cell carcinoma
-
doi:10.1038/sj.bjc.6606061
-
Powles T, Chowdhury S, Jones R, Mantle M, Nathan P, Bex A, et al. Sunitinib and other targeted therapies for renal cell carcinoma. Br J Cancer (2011) 104:741-5. doi:10.1038/sj.bjc.6606061
-
(2011)
Br J Cancer
, vol.104
, pp. 741-745
-
-
Powles, T.1
Chowdhury, S.2
Jones, R.3
Mantle, M.4
Nathan, P.5
Bex, A.6
-
61
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
doi:10.1056/NEJMoa1003466
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med (2010) 363:711-23. doi:10.1056/NEJMoa1003466
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
62
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
doi:10.1056/NEJMoa1200694
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med (2012) 366:2455-65. doi:10.1056/NEJMoa1200694
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
-
63
-
-
84877882244
-
Anti-programmed death-1 and anti-programmed death-ligand 1 antibodies in cancer therapy
-
doi:10.1517/14712598.2013.770836
-
Hamid O, Carvajal RD. Anti-programmed death-1 and anti-programmed death-ligand 1 antibodies in cancer therapy. Expert Opin Biol Ther (2013) 13:847-61. doi:10.1517/14712598.2013.770836
-
(2013)
Expert Opin Biol Ther
, vol.13
, pp. 847-861
-
-
Hamid, O.1
Carvajal, R.D.2
|