Mutational analysis of HBs Ag-positive mothers and their infected children despite immunoprophylaxis

Iranian Journal of Allergy, Asthma and Immunology

Volumn 12, Issue 4, 2013, Pages 352-360

  Ghaziasadi, Azam ^a   Alavian, Seyed Moayed ^b   Norouzi, Mehdi ^a   Fazeli, Zeinab ^a   Jazayeri, Seyed Mohammad ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b BAQIYATALLAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

HBV escape mutants; HBV prophylaxis; Hepatitis B immunoglobulin

Indexed keywords

AMINO ACID; EPITOPE; HEPATITIS B ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE;

ARTICLE; CHILD; CLINICAL ARTICLE; DNA EXTRACTION; FEMALE; GENE SEQUENCE; GENOME; HEPATITIS B; HIGH RISK PATIENT; HUMAN; IMMUNOPROPHYLAXIS; MOTHER; MUTATIONAL ANALYSIS; POLYMERASE CHAIN REACTION; SERUM; VACCINATION; VERTICAL TRANSMISSION; WILD TYPE;

FEMALE; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HEPATITIS B VIRUS; HUMANS; IMMUNOGLOBULINS; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MUTATION; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

EID: 84888229663     PISSN: 17351502     EISSN: 17355249     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Visvanathan K, Lewin SR. Immunopathogenesis: role of innate and adaptive immune responses. Semin Liver Dis 2006; 26(2):104-15. (Pubitemid 43668253)
2. Zuckerman JN. Review: hepatitis B immune globulin for prevention of hepatitis B infection. J Med Virol 2007; 79(7):919-21. (Pubitemid 46871547)
3. Moradi A, Khodabakhshi B, Roshandel G, Kalavi K, Besharat S, Semnani S. Response to the Hepatitis B Virus Vaccine in Iranian Infants. Hepat Mon 2009; 9(3):229-31.
4. Salkic NN. Intrafamilial Transmission of Hepatitis B: Experience and Lessons Learned in Bosnia and Herzegovina. Hepat Mon 2009; 9(3):169-70.
5. Yamamoto K, Horikita M, Tsuda F, Itoh K, Akahane Y, Yotsumoto S, et al. Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen. J Virol 1994; 68(4):2671-6. (Pubitemid 24091946)
6. Carman WF, Korula J, Wallace L, MacPhee R, Mimms L, Decker R. Fulminant reactivation of hepatitis B due to envelope protein mutant that escaped detection by monoclonal HBsAg ELISA. Lancet 1995; 345(8962):1406-7.
7. Carman WF. The clinical significance of surface antigen variants of hepatitis B virus. J Viral Hepat 1997; 4 Suppl 1:11-20.
8. Ghany MG, Ayola B, Villamil FG, Gish RG, Rojter S, Vierling JM, et al. Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis. Hepatology 1998; 27(1):213-22.
9. Protzer-Knolle U, Naumann U, Bartenschlager R, Berg T, Hopf U, Meyer zum Buschenfelde KH, et al. Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation. Hepatology 1998; 27(1):254-63.
10. Ireland JH, O'Donnell B, Basuni AA, Kean JD, Wallace LA, Lau GK, et al. Reactivity of 13 in vitro expressed hepatitis B surface antigen variants in 7 commercial diagnostic assays. Hepatology 2000; 31(5):1176-82. (Pubitemid 30233244)
11. Weber B. Diagnostic impact of the genetic variability of the hepatitis B virus surface antigen gene. J Med Virol 2006; 78 Suppl 1:S59-65. (Pubitemid 43993468)
12. Hollinger FB, Sood G. Occult hepatitis B virus infection: a covert operation. J Viral Hepat 2010; 17(1):1-15.
13. Hsu HY, Chang MH, Ni YH, Lin HH, Wang SM, Chen DS. Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis. Hepatology 1997; 26(3):786-91.
14. Oon CJ, Chen WN, Goo KS, Goh KT. Intra-familial evidence of horizontal transmission of hepatitis B virus surface antigen mutant G145R. J Infect 2000; 41(3):260-4. (Pubitemid 32051047)
15. Chen WN, Oon CJ, Koh S. Horizontal transmission of a hepatitis B virus surface antigen mutant. J Clin Microbiol 2000; 38(2):938-9. (Pubitemid 30082720)
16. Chen WN, Oon CJ. Hepatitis B virus surface antigen (HBsAg) mutants in Singapore adults and vaccinated children with high anti-hepatitis B virus antibody levels but negative for HBsAg. J Clin Microbiol 2000; 38(7):2793-4.
17. Mele A, Tancredi F, Romano L, Giuseppone A, Colucci M, Sangiuolo A, et al. Effectiveness of hepatitis B vaccination in babies born to hepatitis B surface antigen-positive mothers in Italy. J Infect Dis 2001; 184(7):905-8. (Pubitemid 32881096)
18. Friedt M, Gerner P, Wintermeyer P, Wirth S. Complete hepatitis B virus genome analysis in HBsAg positive mothers and their infants with fulminant hepatitis B. BMC Gastroenterol 2004; 4:11.
19. Alavian SM, Hajariazdeh B, Ahmadzad Asl M, Kabir A, Bagheri Lankarani K. Hepatitis B Virus Infection in Iran: A Systematic Review. Hepat Mon 2008; 8(4):281-94.
20. Nokhodian Z, Kassaian N, Ataei B, Javadi AA, Shoaei P, Farajzadegan Z, et al. Hepatitis B Markers in Isfahan, Central Iran: A Population-Based Study. Hepat Mon 2009; 9(1):12-6.
21. Hajiani E, Hashemi S, Masjedizadeh A. Seroepidemiology of Hepatitis B Virus Infection in Khuzestan Province, Southwest of Iran. Hepat Mon 2009; 9(1):34-8.
22. Alavian SM. Ministry of Health in Iran Is Serious about Controlling Hepatitis B. Hepat Mon 2007; 7(1):3-5.
23. Alavian SM, Gooya MM, Hajarizadeh B, Esteghamati AR, Moeinzadeh AM, Haghazali M, et al. Mass Vaccination Campaign against Hepatitis B in Adolescents in Iran: Estimating Coverage using Administrative Data. Hepat Mon 2009; 9(3):189-95.
24. Hosseini SM, Ranjbar R, Abolghasemi H, Turkaman M. Evaluation of the Level of HBV Antibody Titer after HBV Vaccination among Children in Tehran, Iran. Hepat Mon 2009; 9(2):150-3.
25. Adibi P, Ghassemian R, Alavian SM, Ranjbar M, Mohammadalizadeh AH, Nematizadeh F, et al. Effectiveness of hepatitis B vaccination in children of chronic hepatitis B mothers. Saudi Med J 2004; 25:1414-18. (Pubitemid 39429595)
26. Estévez ZC, Silva CV, Arias EP. On the Comparison of Two HBV Recombinant Vaccines. Hepat Mon 2010; 10(3):223-5.
27. Gunther S, Li BC, Miska S, Kruger DH, Meisel H, Will H. A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J Virol 1995; 69(9):5437-44.
28. Jazayeri M, Basuni AA, Sran N, Gish R, Cooksley G, Locarnini S, et al. HBV core sequence: definition of genotype-specific variability and correlation with geographical origin. J Viral Hepat 2004; 11(6):488-501. (Pubitemid 39486612)
29. Goodarzi Z, Malekzadeh R, Montazeri G, Alavian SM, Qurbanalizadgan M, Daram M, et al. Phylogenetic Analysis of HBV Based on PreS Region in Iranian Hepatocellular Carcinoma Patients. Hepat Mon 2007; 7(4):201-5.
30. Liu XH, Lin J, Zhang SH, Zhang SM, Feitelson MA, Gao HJ, et al. COOH-terminal deletion of HBx gene is a frequent event in HBV-associated hepatocellular carcinoma. World J Gastroenterol 2008; 14(9):1346-52. (Pubitemid 351425212)
31. Fujii H, Moriyama K, Sakamoto N, Kondo T, Yasuda K, Hiraizumi Y, et al. Gly145 to Arg substitution in HBs antigen of immune escape mutant of hepatitis B virus. Biochem Biophys Res Commun 1992; 184(3):1152-7.
32. Lee PI, Chang LY, Lee CY, Huang LM, Chang MH. Detection of hepatitis B surface gene mutation in carrier children with or without immunoprophylaxis at birth. J Infect Dis 1997; 176(2):427-30.
33. Carman WF, Zanetti AR, Karayiannis P, Waters J, Manzillo G, Tanzi E, et al. Vaccine-induced escape mutant of hepatitis B virus. Lancet 1990; 336(8711):325-9. (Pubitemid 20264145)
34. Ngui SL, O'Connell S, Eglin RP, Heptonstall J, Teo CG. Low detection rate and maternal provenance of hepatitis B virus S gene mutants in cases of failed postnatal immunoprophylaxis in England and Wales. J Infect Dis 1997; 176(5):1360-5. (Pubitemid 27461004)
35. Ferrari C, Bertoletti A, Penna A, Cavalli A, Valli A, Missale G, et al. Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen. J Clin Invest 1991; 88(1):214-22.
36. Mizukoshi E, Sidney J, Livingston B, Ghany M, Hoofnagle JH, Sette A, et al. Cellular immune responses to the hepatitis B virus polymerase. J Immunol 2004; 173(9):5863-71. (Pubitemid 39392177)
37. Mu SC, Lin YM, Jow GM, Chen BF. Occult hepatitis B virus infection in hepatitis B vaccinated children in Taiwan. J Hepatol 2009; 50(2):264-72.
38. Carman WF, Jacyna MR, Hadziyannis S, Karayiannis P, McGarvey MJ, Makris A, et al. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 1989; 2(8663):588-91. (Pubitemid 19216208)
39. Mesenas SJ, Chow WC, Zhao Y, Lim GK, Oon CJ, Ng HS. Wild-type and 'a' epitope variants in chronic hepatitis B virus carriers positive for hepatitis B surface antigen and antibody. J Gastroenterol Hepatol 2002; 17(2):148-52. (Pubitemid 34415667)
40. Schranz P, Zentgraf H, Loncarevic IF, Niepmann M, Schroder CH. Defective replication units of hepatitis B virus. J Virol 1990; 64(4):1851-4. (Pubitemid 20104929)
41. Alexopoulou A, Karayiannis P, Hadziyannis SJ, Aiba N, Thomas HC. Emergence and selection of HBV variants in an anti-HBe positive patient persistently infected with quasi-species. J Hepatol 1997; 26(4):748-53. (Pubitemid 27145695)
42. Guo J, Yao L, Chen A, Xu Y, Liu X, Shu Y, et al. [Immunological evaluation of vector-expressed M2 and HA genes of H5N1 influenza virus in mice]. Sheng Wu Gong Cheng Xue Bao 2010; 26(5):649-56.
43. Hsu HY, Chang MH, Liaw SH, Ni YH, Chen HL. Changes of hepatitis B surface antigen variants in carrier children before and after universal vaccination in Taiwan. Hepatology 1999; 30(5):1312-7.
44. Ogata N, Zanetti AR, Yu M, Miller RH, Purcell RH. Infectivity and pathogenicity in chimpanzees of a surface gene mutant of hepatitis B virus that emerged in a vaccinated infant. J Infect Dis 1997; 175(3):511-23. (Pubitemid 27086153)