Treatment of older patients with HER2-positive metastatic breast cancer with pertuzumab, trastuzumab, and docetaxel: Subgroup analyses from a randomized, double-blind, placebo-controlled phase III trial (CLEOPATRA)

Breast Cancer Research and Treatment

Volumn 142, Issue 1, 2013, Pages 89-99

  Miles, David ^a   Baselga, José ^b   Amadori, Dino ^c   Sunpaweravong, Patrapim ^d   Semiglazov, Vladimir ^e   Knott, Adam ^f   Clark, Emma ^f   Ross, Graham ^f   Swain, Sandra M ^g  

^a MOUNT VERNON CANCER CENTRE   (United Kingdom)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c DEPARTMENT OF MEDICAL ONCOLOGY   (Italy)

^d PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^e N N PETROV RESEARCH INSTITUTE OF ONCOLOGY   (Russian Federation)

^f ROCHE PRODUCTS LTD   (United Kingdom)

^g WASHINGTON CANCER INSTITUTE   (United States)

Author keywords

Elderly; HER2; Metastatic breast cancer; Older women; Pertuzumab; Trastuzumab

Indexed keywords

ANTHRACYCLINE; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GRANULOCYTE COLONY STIMULATING FACTOR; PERTUZUMAB; PLACEBO; TRASTUZUMAB;

ADULT; AGE DISTRIBUTION; AGED; ALOPECIA; ANEMIA; ARTICLE; ASTHENIA; BREAST CANCER; CANCER RADIOTHERAPY; CONTROLLED STUDY; DECREASED APPETITE; DIARRHEA; DISEASE FREE INTERVAL; DOUBLE BLIND PROCEDURE; DRUG DOSE ESCALATION; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; DYSGEUSIA; FATIGUE; FEBRILE NEUTROPENIA; GRANULOCYTOPENIA; HEMATOLOGIC DISEASE; HUMAN; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; LEUKOPENIA; LOADING DRUG DOSE; LYMPHATIC SYSTEM DISEASE; MAJOR CLINICAL STUDY; METASTASIS; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; PERIPHERAL EDEMA; PERIPHERAL NEUROPATHY; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL; RASH; VOMITING;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM METASTASIS; RECEPTOR, ERBB-2; TAXOIDS; TREATMENT OUTCOME;

EID: 84888228586     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2710-z     Document Type: Article

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