Effect of exchange of the cysteine molybdenum ligand with selenocysteine on the structure and function of the active site in human sulfite oxidase

Biochemistry

Volumn 52, Issue 46, 2013, Pages 8295-8303

  Reschke, Stefan ^a   Niks, Dimitri ^b   Wilson, Heather ^c   Sigfridsson, Kajsa G V ^d   Haumann, Michael ^d   Rajagopalan, K V ^c   Hille, Russ ^b   Leimkühler, Silke ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE RESIDUES; ELECTRON PARAMAGNETIC RESONANCES (EPR); MOLYBDENUM-COFACTOR; OXIDIZING ACTIVITY; PROTEIN EXPRESSIONS; SITE DIRECTED MUTAGENESIS; SPECIFIC BINDING; SULFITE OXIDASE;

ESCHERICHIA COLI; LIGANDS; MAGNETIC RESONANCE; METAL IONS; MOLYBDENUM; SULFUR; X RAY ABSORPTION SPECTROSCOPY;

AMINO ACIDS;

CYSTEINE; LIGAND; MOLYBDENUM; MOLYBDOPTERIN; SELENOCYSTEINE; SULFITE OXIDASE;

ARTICLE; CHICKEN; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEGRADATION; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; ESCHERICHIA COLI; GEOMETRY; HUMAN; KINETICS; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; WILD TYPE; X RAY ABSORPTION SPECTROSCOPY;

CATALYTIC DOMAIN; COENZYMES; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIGANDS; METALLOPROTEINS; MOLYBDENUM; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PTERIDINES; SELENOCYSTEINE; X-RAY ABSORPTION SPECTROSCOPY;

EID: 84888209794     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4008512     Document Type: Article

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