-
1
-
-
0003770851
-
-
American Diabetes Association. Available from Accessed September 14, 2013
-
American Diabetes Association. Diabetes Statistics. Available from http://www.diabetes.org/diabetes-basics/diabetes-statistics/. Accessed September 14, 2013.
-
Diabetes Statistics
-
-
-
2
-
-
84875637478
-
More patients get good diabetes control, but only a minority meet all goals
-
Mitka M. More patients get good diabetes control, but only a minority meet all goals. JAMA. 2013;309(13):1335-1336.
-
(2013)
JAMA.
, vol.309
, Issue.13
, pp. 1335-1336
-
-
Mitka, M.1
-
3
-
-
84866268783
-
Management of hyperglycemia in type 2 diabetes: A patient-centered approach
-
Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
Inzucchi SE, Bergenstal RM, Buse JB, et al;position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Management of hyperglycemia in type 2 diabetes: a patient-centered approach. Diabetes Care. 2012;35(10): 1364-1379.
-
(2012)
Diabetes Care
, vol.35
, Issue.10
, pp. 1364-1379
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
4
-
-
77954242599
-
SGLT2 Inhibition-a novel strategy for diabetes treatment
-
Chao EC, Henry RR. SGLT2 Inhibition-a novel strategy for diabetes treatment. Nat Rev Drug Discov. 2010;9(7):551-559.
-
(2010)
Nat Rev Drug Discov.
, vol.9
, Issue.7
, pp. 551-559
-
-
Chao, E.C.1
Henry, R.R.2
-
5
-
-
0034997336
-
Renal Na+ glucose cotransporters
-
Wright EM. Renal Na+ glucose cotransporters. Am J Physiol Renal Physiol. 2001;280(1):F10-F18.
-
(2001)
Am J Physiol Renal Physiol.
, vol.280
, Issue.1
-
-
Wright, E.M.1
-
6
-
-
12644311551
-
Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2
-
Mackenzie B, Loo DD, Panayotova-Heiermann M, Wright EM. Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2. J Biol Chem. 1996;271(51):32678-32683.
-
(1996)
J Biol Chem.
, vol.271
, Issue.51
, pp. 32678-32683
-
-
Mackenzie, B.1
Loo, D.D.2
Panayotova-Heiermann, M.3
Wright, E.M.4
-
7
-
-
0028044629
-
The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose
-
Kanai Y, Lee WS, You G, Brown D, Hediger MA. The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. J Clin Invest. 1994;93(1): 397-404.
-
(1994)
J Clin Invest.
, vol.93
, Issue.1
, pp. 397-404
-
-
Kanai, Y.1
Lee, W.S.2
You, G.3
Brown, D.4
Hediger, M.A.5
-
8
-
-
64749094872
-
Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose
-
Farber SJ, Berger EY, Earle DP. Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose. J Clin Invest. 1951;30(2):125-129.
-
(1951)
J Clin Invest.
, vol.30
, Issue.2
, pp. 125-129
-
-
Farber, S.J.1
Berger, E.Y.2
Earle, D.P.3
-
9
-
-
79956331954
-
Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects
-
Sha S, Devineni D, Ghosh A, et al. Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects. Diabetes Obes Metab. 2011;13: 669-672.
-
(2011)
Diabetes Obes Metab.
, vol.13
, pp. 669-672
-
-
Sha, S.1
Devineni, D.2
Ghosh, A.3
-
10
-
-
84877865378
-
Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: Results of a randomized, placebo-controlled study
-
Polidori D, Sha S, Mudaliar S, et al. Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: results of a randomized, placebo-controlled study. Diabetes Care. 2013;36(8):2154-2161.
-
(2013)
Diabetes Care.
, vol.36
, Issue.8
, pp. 2154-2161
-
-
Polidori, D.1
Sha, S.2
Mudaliar, S.3
-
11
-
-
84888163835
-
-
INVOKANA® (canagliflozin) [package insert]. Titusville, NJ: Janssen Pharmaceuticals, Inc
-
INVOKANA® (canagliflozin) [package insert]. Titusville, NJ: Janssen Pharmaceuticals, Inc;2013.
-
(2013)
-
-
-
12
-
-
84874291673
-
Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
-
Stenlöf K, Cefalu WT, Kim KA, et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab. 2013;15(4):372-382.
-
(2013)
Diabetes Obes Metab.
, vol.15
, Issue.4
, pp. 372-382
-
-
Stenlöf, K.1
Cefalu, W.T.2
Kim, K.A.3
-
13
-
-
84861781220
-
Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes
-
Canagliflozin DIA 2001 Study Group
-
Rosenstock J, Aggarwal N, Polidori D, et al;Canagliflozin DIA 2001 Study Group. Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes. Diabetes Care. 2012;35(6):1232-1238.
-
(2012)
Diabetes Care
, vol.35
, Issue.6
, pp. 1232-1238
-
-
Rosenstock, J.1
Aggarwal, N.2
Polidori, D.3
-
14
-
-
84891784200
-
Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea
-
Schernthaner G, Gross JL, Rosenstock J, et al. Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea. Diabetes Care. 2013;36(9):2508-2515.
-
(2013)
Diabetes Care.
, vol.36
, Issue.9
, pp. 2508-2515
-
-
Schernthaner, G.1
Gross, J.L.2
Rosenstock, J.3
-
15
-
-
84860252876
-
Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin
-
Devineni, D, Morrow L, Hompesch M, et al. Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin. Diabetes Obes Metab. 2012;14(6): 539-545.
-
(2012)
Diabetes Obes Metab.
, vol.14
, Issue.6
, pp. 539-545
-
-
Devineni, D.1
Morrow, L.2
Hompesch, M.3
-
16
-
-
84876311251
-
Efficacy and safety of canagliflozin in subjects with type 2 diabetes and chronic kidney disease
-
Yale JF, Bakris G, Cariou B, et al. Efficacy and safety of canagliflozin in subjects with type 2 diabetes and chronic kidney disease. Diabetes Obes Metab. 2013;15(5):463-473.
-
(2013)
Diabetes Obes Metab.
, vol.15
, Issue.5
, pp. 463-473
-
-
Yale, J.F.1
Bakris, G.2
Cariou, B.3
-
17
-
-
84880543926
-
Efficacy and safety of canagliflozin treatment in older subjects with type 2 diabetes mellitus: A randomized trial
-
Bode B, Stenlöf K, Sullivan D, Fung A, Usiskin K. Efficacy and safety of canagliflozin treatment in older subjects with type 2 diabetes mellitus: a randomized trial. Hosp Pract. 2013;41(2):72-84.
-
(2013)
Hosp Pract.
, vol.41
, Issue.2
, pp. 72-84
-
-
Bode, B.1
Stenlöf, K.2
Sullivan, D.3
Fung, A.4
Usiskin, K.5
-
18
-
-
84888141518
-
-
GoodRx [webpage on the Internet]. Available from: Accessed September 15, 2013
-
GoodRx [webpage on the Internet]. Available from: http://www.goodRx.com. Accessed September 15, 2013.
-
-
-
-
19
-
-
84880924263
-
Rationale, design, and baseline characteristics of the canagliflozin cardiovascular assessment study (CANVAS)-a randomized placebo controlled trial
-
Neal B, Perkovic V, de Zeeue D, et al. Rationale, design, and baseline characteristics of the canagliflozin cardiovascular assessment study (CANVAS)-a randomized placebo controlled trial. Am Heart J. 2013;166(2);217-223.
-
(2013)
Am Heart J.
, vol.166
, Issue.2
, pp. 217-223
-
-
Neal, B.1
Perkovic, V.2
de Zeeue, D.3
-
20
-
-
84864146681
-
LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial
-
Zambrowicz B, Freiman J, Brown PM, et al. LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial. Clin Pharmacol Ther. 2012;92(2):158-169.
-
(2012)
Clin Pharmacol Ther.
, vol.92
, Issue.2
, pp. 158-169
-
-
Zambrowicz, B.1
Freiman, J.2
Brown, P.M.3
|