B7-H3 is a new cancer-specific endothelial marker in clear cell renal cell carcinoma

OncoTargets and Therapy

Volumn 6, Issue , 2013, Pages 1667-1673

  Qin, Xiaojian ^a,b   Zhang, Hailiang ^a,b   Ye, Dingwei ^a,b   Dai, Bo ^a,b   Zhu, Yao ^a,b   Shi, Guohai ^a,b  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

B7 H3; Biomarkers; Clear cell renal cell carcinoma; Endothelial cell; Kidney

Indexed keywords

CELL MARKER; MESSENGER RNA; PARAFFIN; TUMOR MARKER;

ADULT; AGED; ARTICLE; B7 H3 GENE; CONTROLLED STUDY; CORPUS LUTEUM; DISEASE ASSOCIATION; ENDOTHELIUM CELL; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; MAJOR CLINICAL STUDY; MALE; METASTASIS; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; TUMOR VASCULARIZATION;

EID: 84888164273     PISSN: 11786930     EISSN: None     Source Type: Journal    
DOI: 10.2147/OTT.S53565     Document Type: Article

References (15)

1. Lainakis G, Bamias A. Targeting angiogenesis in renal cell carcinoma. Curr Cancer Drug Targets. 2008;8(5):349-358.
2. Chapoval AI, Ni J, Lau JS, et al. B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol. 2001;2(3): 269-274.
3. Seaman S, Stevens J, Yang MY, Logsdon D, Graff-Cherry C, St Croix B. Genes that distinguish physiological and pathological angiogenesis. Cancer Cell. 2007;11(6):539-554.
4. Crispen PL, Sheinin Y, Roth TJ, et al. Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma. Clin Cancer Res. 2008;14(16):5150-5157.
5. Pusztaszeri MP, Seelentag W, Bosman FT. Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues. J Histochem Cytochem. 2006;54(4): 385-395.
6. Steinberger P, Majdic O, Derdak SV, et al. Molecular characterization of human 4Ig-B7-H3, a member of the B7 family with four Ig-like domains. J Immunol. 2004;172(4):2352-2359.
7. Loos M, Hedderich DM, Friess H, Kleeff J. B7-H3 and its role in antitumor immunity. Clin Dev Immunol. 2010;2010:683875.
8. Loo D, Alderson RF, Chen FZ, et al. Development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent antitumor activity. Clin Cancer Res. 2012;18(14):3834-3845.
9. St Croix B, Rago C, Velculescu V, et al. Genes expressed in human tumor endothelium. Science. 2000;289(5482):1197-1202.
10. Nanda A, Carson-Walter EB, Seaman S, et al. TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI). Cancer Res. 2004;64(3): 817-820.
11. Chaudhary A, Hilton MB, Seaman S, et al. TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types. Cancer Cell. 2012;21(2): 212-226.
12. Mancuso P, Burlini A, Pruneri G, Goldhirsch A, Martinelli G, Bertolini F. Resting and activated endothelial cells are increased in the peripheral blood of cancer patients. Blood. 2001;97(11):3658-3661.
13. Bertolini F, Shaked Y, Mancuso P, Kerbel RS. The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer. 2006;6(11):835-845.
14. Furstenberger G, von Moos R, Senn HJ, Boneberg EM. Real-time PCR of CD146 mRNA in peripheral blood enables the relative quantification of circulating endothelial cells and is an indicator of angiogenesis. Br J Cancer. 2005;93(7):793-798.
15. Hioki T, Sugimura Y. [Detection of circulating cancer cells by nested reverse transcription-polymerase chain reaction of cytokeratin-19 in patients with renal cell carcinoma.] Hinyokika Kiyo. 1999;45(8):577-581. Japanese.