Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin

DNA Repair

Volumn 12, Issue 12, 2013, Pages 1159-1164

  Krokeide, Silje Z ^a   Laerdahl, Jon K ^a   Salah, Medya ^a   Luna, Luisa ^a   Cederkvist, F Henning ^a   Fleming, Aaron M ^b   Burrows, Cynthia J ^b   Dalhus, Bjørn ^a   Bjørås, Magnar ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Base excision repair; DNA damage; DNA glycosylase; Human NEIL3; Mouse Neil3; Oxidation

Indexed keywords

DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; GUANIDINOHYDANTOIN; HYDANTOIN DERIVATIVE; NEIL3 PROTEIN; SPIROIMINDIOHYDANTOIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DNA DAMAGE; ENZYME SPECIFICITY; EXCISION REPAIR; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

2,6-DIAMINO-4-HYDROXY-5-FORMAMIDOPYRIMIDINE; 5-HYDROXY-2′-DEOXYCYTIDINE; 5-HYDROXY-2′-DEOXYURIDINE; 5OHC; 5OHU; AP; APURINIC/APYRIMIDINIC; BASE EXCISION REPAIR; BER; COLUMN VOLUME; CORE GLYCOSYLASE DOMAIN; CV; DNA DAMAGE; DNA GLYCOSYLASE; DOUBLE-STRANDED; DS; E. COLI ENDONUCLEASE VIII; E. COLI ENDONUCLEASE VIII-LIKE; ENDONUCLEASE III; ESCHERICHIA COLI FORMAMIDOPYRIMIDINE DNA GLYCOSYLASE; FAPY; FPG; GD; GH; GUANIDINOHYDANTOIN; H2TH; HELIX-TWO-TURN-HELIX; HUMAN NEIL3; MCS; MOUSE NEIL3; MULTIPLE CLONING SITE; NEI; NEIL; NTH; OXIDATION; REACTIVE OXYGEN SPECIES; ROS; SINGLE-STRANDED; SP; SPIROIMINODIHYDANTOIN; SS; UDG; URACIL DNA GLYCOSYLASE;

CATALYTIC DOMAIN; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA BREAKS, SINGLE-STRANDED; DNA GLYCOSYLASES; DNA REPAIR; GUANIDINES; GUANOSINE; HUMANS; HYDANTOINS; LYSINE; MUTATION; N-GLYCOSYL HYDROLASES; RECOMBINANT PROTEINS; SPIRO COMPOUNDS; SUBSTRATE SPECIFICITY;

EID: 84888129884     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.04.026     Document Type: Article

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