-
4
-
-
0025740249
-
Current understanding of the etiology of obesity: Genetic and nongenetic factors
-
Bouchard C. Current understanding of the etiology of obesity: genetic and nongenetic factors. Am J Clin Nutr 1991; 53:1561S-1565S.
-
(1991)
Am J Clin Nutr
, vol.53
-
-
Bouchard, C.1
-
6
-
-
0029901391
-
The heritability of body mass index among an international sample of monozygotic twins reared apart
-
Allison DB, Kaprio J, Korkeila M, et al. The heritability of body mass index among an international sample of monozygotic twins reared apart. Int J Obes Relat Metab Disord 1996; 20:501-506.
-
(1996)
Int J Obes Relat Metab Disord
, vol.20
, pp. 501-506
-
-
Allison, D.B.1
Kaprio, J.2
Korkeila, M.3
-
8
-
-
0030843960
-
Genetic and environmental factors in relative body weight and human adiposity
-
Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet 1997; 27:325-351.
-
(1997)
Behav Genet
, vol.27
, pp. 325-351
-
-
Maes, H.H.1
Neale, M.C.2
Eaves, L.J.3
-
10
-
-
0026683993
-
Genetic and environmental contributions to the variance of body height in a sample of first and second degree relatives
-
Tambs K, Moum T, Eaves LJ, et al. Genetic and environmental contributions to the variance of body height in a sample of first and second degree relatives. Am J Phys Anthropol 1992; 88:285-294.
-
(1992)
Am J Phys Anthropol
, vol.88
, pp. 285-294
-
-
Tambs, K.1
Moum, T.2
Eaves, L.J.3
-
11
-
-
0023899628
-
Inheritance of the amount and distribution of human body fat
-
Bouchard C, Perusse L, Leblanc C, et al. Inheritance of the amount and distribution of human body fat. Int J Obes 1988; 12:205-215.
-
(1988)
Int J Obes
, vol.12
, pp. 205-215
-
-
Bouchard, C.1
Perusse, L.2
Leblanc, C.3
-
12
-
-
0028857453
-
Influences of genes and shared family environment on adult body mass index assessed in an adoption study by a comprehensive path model
-
Vogler GP, Sorensen TI, Stunkard AJ, et al. Influences of genes and shared family environment on adult body mass index assessed in an adoption study by a comprehensive path model. Int J Obes Relat Metab Disord 1995;19:40-45.
-
(1995)
Int J Obes Relat Metab Disord
, vol.19
, pp. 40-45
-
-
Vogler, G.P.1
Sorensen, T.I.2
Stunkard, A.J.3
-
13
-
-
0000581558
-
The response to exercise with constant energy intake in identical twins
-
Bouchard C, Tremblay A, Despres JP, et al. The response to exercise with constant energy intake in identical twins. Obes Res 1994; 2:400-410.
-
(1994)
Obes Res
, vol.2
, pp. 400-410
-
-
Bouchard, C.1
Tremblay, A.2
Despres, J.P.3
-
14
-
-
0242383401
-
Obesity: Is it a genetic disorder
-
Loos RJ, Bouchard C,Obesity: is it a genetic disorder? J Intern Med.2003.254:401-425.
-
(2003)
J Intern Med
, vol.254
, pp. 401-425
-
-
Loos, R.J.1
Bouchard, C.2
-
16
-
-
33749859790
-
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
-
Oh IS, Shimizu H, Satoh T, et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 2006; 443:709-712.
-
(2006)
Nature
, vol.443
, pp. 709-712
-
-
Oh, I.S.1
Shimizu, H.2
Satoh, T.3
-
17
-
-
77954615466
-
Identification of nesfatin-1 in human and murine adipose tissue: A novel depot-specific adipokine with increased levels in obesity
-
Ramanjaneya M, Chen J, Brown JE, et al. Identification of nesfatin-1 in human and murine adipose tissue: a novel depot-specific adipokine with increased levels in obesity. Endocrinology 2010; 151:3169-3180.
-
(2010)
Endocrinology
, vol.151
, pp. 3169-3180
-
-
Ramanjaneya, M.1
Chen, J.2
Brown, J.E.3
-
18
-
-
70350319523
-
Central nesfatin-1 reduces dark-phase food intake and gastric emptying in rats: Differential role of corticotropinreleasing factor2 receptor
-
Stengel A, Goebel M, Wang L, et al. Central nesfatin-1 reduces dark-phase food intake and gastric emptying in rats: differential role of corticotropinreleasing factor2 receptor. Endocrinology 2009; 150:4911-4919.
-
(2009)
Endocrinology
, vol.150
, pp. 4911-4919
-
-
Stengel, A.1
Goebel, M.2
Wang, L.3
-
19
-
-
59649122740
-
Peripheral administration of nesfatin-1 reduces food intake in mice: The leptin-independent mechanism
-
Shimizu H, Oh IS, Hashimoto K, et al. Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism. Endocrinology.2009:150:662-671.
-
(2009)
Endocrinology
, vol.150
, pp. 662-671
-
-
Shimizu, H.1
Oh, I.S.2
Hashimoto, K.3
-
20
-
-
79958026391
-
Association between polymorphisms of the nesfatin gene, NUCB2, and obesity in men
-
Zegers D, Beckers S, Mertens IL, et al. Association between polymorphisms of the nesfatin gene, NUCB2, and obesity in men. Mol Genet Metab 2011;103:282-286.
-
(2011)
Mol Genet Metab
, vol.103
, pp. 282-286
-
-
Zegers, D.1
Beckers, S.2
Mertens, I.L.3
-
21
-
-
84873086131
-
The association of a nucleobindin 2 gene (NUCB2) variant with childhood adiposity
-
Chen YY, Chan RM, Tan KM, et al. The association of a nucleobindin 2 gene (NUCB2) variant with childhood adiposity. Gene 2013; 516:48-52.
-
(2013)
Gene
, vol.516
, pp. 48-52
-
-
Chen, Y.Y.1
Chan, R.M.2
Tan, K.M.3
-
22
-
-
84859575363
-
Genetic determinants of common obesity and their value in prediction
-
Loos RJ. Genetic determinants of common obesity and their value in prediction. Best Pract Res Clin Endocrinol Metab 2012; 26:211-226.
-
(2012)
Best Pract Res Clin Endocrinol Metab
, vol.26
, pp. 211-226
-
-
Loos, R.J.1
-
23
-
-
78049337953
-
Association analyses of 249 796 individuals reveal 18 new loci associated with body mass index
-
Speliotes EK, Willer CJ, Berndt SI, et al. Association analyses of 249 796 individuals reveal 18 new loci associated with body mass index. Nat Genet, 2010.42:937-948.
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
-
24
-
-
0030967953
-
Predicting obesity in young adulthood from childhood and parental obesity
-
Whitaker RC, Wright JA, Pepe MS, et al. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med 1997;337:869-873.
-
(1997)
N Engl J Med
, vol.337
, pp. 869-873
-
-
Whitaker, R.C.1
Wright, J.A.2
Pepe, M.S.3
-
25
-
-
84865323099
-
Obesity susceptibility loci on body mass index and weight loss in Spanish adolescents after a lifestyle intervention
-
e2
-
Moleres A, Rendo-Urteaga T, Zulet MA, et al. Obesity susceptibility loci on body mass index and weight loss in Spanish adolescents after a lifestyle intervention. J Pediatr 2012; 161:466-470; e2.
-
(2012)
J Pediatr
, vol.161
, pp. 466-470
-
-
Moleres, A.1
Rendo-Urteaga, T.2
Zulet, M.A.3
-
26
-
-
84859917347
-
Elements of 'missing heritability'
-
Marian AJ. Elements of 'missing heritability'. Curr Opin Cardiol 2012;27:197-201
-
(2012)
Curr Opin Cardiol
, vol.27
, pp. 197-201
-
-
Marian, A.J.1
-
27
-
-
84856405512
-
The mystery of missing heritability: Genetic interactions create phantom heritability
-
Zuk O, Hechter E, Sunyaev SR, Lander ES. The mystery of missing heritability: genetic interactions create phantom heritability. Proc Natl Acad Sci U S A.2012;109:1193-1198.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
Lander, E.S.4
-
28
-
-
34249337761
-
Perceptions of epigenetics
-
Bird A. Perceptions of epigenetics. Nature 2007; 447:396-398.
-
(2007)
Nature
, vol.447
, pp. 396-398
-
-
Bird, A.1
-
30
-
-
84856239588
-
Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint
-
Gu SG, Pak J, Guang S, et al. Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint. Nat Genet 2012; 44:157-164.
-
(2012)
Nat Genet
, vol.44
, pp. 157-164
-
-
Gu, S.G.1
Pak, J.2
Guang, S.3
-
31
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
Heijmans BT, Tobi EW, Stein AD, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A 2008; 105:17046-17049.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
Tobi, E.W.2
Stein, A.D.3
-
32
-
-
79955594736
-
Child health, developmental plasticity, and epigenetic programming
-
Hochberg Z, Feil R, Constancia M, et al. Child health, developmental plasticity, and epigenetic programming. Endocr Rev 2011; 32:159-224.
-
(2011)
Endocr Rev
, vol.32
, pp. 159-224
-
-
Hochberg, Z.1
Feil, R.2
Constancia, M.3
-
33
-
-
0017305263
-
Obesity in young men after famine exposure in utero and early infancy
-
Ravelli GP, Stein ZA, Susser MW. Obesity in young men after famine exposure in utero and early infancy. N Engl J Med 1976; 295:349-353.
-
(1976)
N Engl J Med
, vol.295
, pp. 349-353
-
-
Ravelli, G.P.1
Stein, Z.A.2
Susser, M.W.3
-
34
-
-
0032716565
-
Obesity at the age of 50 y in men and women exposed to famine prenatally
-
Ravelli AC, van Der Meulen JH, Osmond C, et al. Obesity at the age of 50 y in men and women exposed to famine prenatally. Am J Clin Nutr 1999; 70:811-816.
-
(1999)
Am J Clin Nutr
, vol.70
, pp. 811-816
-
-
Ravelli, A.C.1
Van Der Meulen, J.H.2
Osmond, C.3
-
35
-
-
79957834770
-
Epigenetic gene promoter methylation at birth is associated with child's later adiposity
-
Godfrey KM, Sheppard A, Gluckman PD, et al. Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes 2011;60:1528-1534
-
(2011)
Diabetes
, vol.60
, pp. 1528-1534
-
-
Godfrey, K.M.1
Sheppard, A.2
Gluckman, P.D.3
-
36
-
-
84859586172
-
DNA methylation patterns in cord blood DNA and body size in childhood
-
Relton CL, Groom A, St Pourcain B, et al. DNA methylation patterns in cord blood DNA and body size in childhood. PloS One 2012; 7:e31821.
-
(2012)
PloS One
, vol.7
-
-
Relton, C.L.1
Groom, A.2
St Pourcain, B.3
-
37
-
-
84878769670
-
Differential DNA methylation patterns between high and low responders to a weight loss intervention in overweight or obese adolescents: The EVASYON study
-
Moleres A, Campion J, Milagro FI, et al. Differential DNA methylation patterns between high and low responders to a weight loss intervention in overweight or obese adolescents: the EVASYON study. FASEB J 2013; 27:2504-2512
-
(2013)
FASEB J
, vol.27
, pp. 2504-2512
-
-
Moleres, A.1
Campion, J.2
Milagro, F.I.3
-
38
-
-
60049085382
-
The role of leptin-melanocortin system and human weight regulation: Lessons from experiments of nature
-
Lee YS. The role of leptin-melanocortin system and human weight regulation: lessons from experiments of nature. Ann Acad Med 2009; 38:34-44.
-
(2009)
Ann Acad Med
, vol.38
, pp. 34-44
-
-
Lee, Y.S.1
-
39
-
-
0028134706
-
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain
-
Mountjoy KG, Mortrud MT, Low MJ, et al. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 1994; 8:1298-1308.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 1298-1308
-
-
Mountjoy, K.G.1
Mortrud, M.T.2
Low, M.J.3
-
40
-
-
0032524392
-
Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems
-
Mountjoy KG, Wild JM. Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems. Brain Res Dev Brain Res. 1998;107:309-314.
-
(1998)
Brain Res Dev Brain Res
, vol.107
, pp. 309-314
-
-
Mountjoy, K.G.1
Wild, J.M.2
-
41
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997; 88:131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
-
42
-
-
0033927916
-
Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
-
Vaisse C, Clement K, Durand E, et al. Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 2000;106:253-262.
-
(2000)
J Clin Invest
, vol.106
, pp. 253-262
-
-
Vaisse, C.1
Clement, K.2
Durand, E.3
-
43
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
Farooqi IS, Keogh JM, Yeo GS, et al. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 2003;348:1085-1095.
-
(2003)
N Engl J Med
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.3
-
44
-
-
0036257961
-
Low frequency of melanocortin-4 receptor (MC4R) mutations in a Mediterranean population with earlyonset obesity
-
Miraglia Del Giudice E, Cirillo G, Nigro V, et al.Low frequency of melanocortin-4 receptor (MC4R) mutations in a Mediterranean population with earlyonset obesity. Int J Obes Relat Metab Disord. 2002;26:647-651.
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 647-651
-
-
Miraglia Del Giudice, E.1
Cirillo, G.2
Nigro, V.3
-
45
-
-
18644363563
-
Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: The swedish obese subjects, the heritage family study, and a memphis cohort
-
Jacobson P, Ukkola O, Rankinen T, et al. Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: the Swedish Obese Subjects, the HERITAGE Family Study, and a Memphis cohort. J Clin Endocrinol Metab 2002; 87:4442-4446.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 4442-4446
-
-
Jacobson, P.1
Ukkola, O.2
Rankinen, T.3
-
46
-
-
0141564582
-
Melanocortin-4 receptor gene: Casecontrol study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity
-
Hinney A, Hohmann S, Geller F, et al. Melanocortin-4 receptor gene: casecontrol study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity. J Clin Endocrinol Metab 2003; 88:4258-4267.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4258-4267
-
-
Hinney, A.1
Hohmann, S.2
Geller, F.3
-
47
-
-
0033495921
-
Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese
-
Ohshiro Y, Sanke T, Ueda K, et al. Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese. Ann Hum Genet.1999;63:483-487.
-
(1999)
Ann Hum Genet
, vol.63
, pp. 483-487
-
-
Ohshiro, Y.1
Sanke, T.2
Ueda, K.3
-
48
-
-
12244281827
-
Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity
-
Larsen LH, Echwald SM, Sorensen TI, et al. Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity. J Clin Endocrinol Metab 2005; 90:219-224.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 219-224
-
-
Larsen, L.H.1
Echwald, S.M.2
Sorensen, T.I.3
-
49
-
-
34347406987
-
The relationship between body mass index and per cent body fat in the severely obese
-
Adams TD, Heath EM, LaMonte MJ, et al. The relationship between body mass index and per cent body fat in the severely obese. Diabetes Obes Metab.2007;9:498-505.
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 498-505
-
-
Adams, T.D.1
Heath, E.M.2
Lamonte, M.J.3
-
50
-
-
33746040561
-
Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population
-
Rong R, Tao YX, Cheung BM, et al. Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population. Clin Endocrinol (Oxf) 2006; 65:198-205.
-
(2006)
Clin Endocrinol (Oxf)
, vol.65
, pp. 198-205
-
-
Rong, R.1
Tao, Y.X.2
Cheung, B.M.3
-
51
-
-
33846489214
-
Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents
-
Wang CL, Liang L, Wang HJ, et al. Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents. J Endocrinol Invest 2006; 29:894-898.
-
(2006)
J Endocrinol Invest
, vol.29
, pp. 894-898
-
-
Wang, C.L.1
Liang, L.2
Wang, H.J.3
-
52
-
-
40749107004
-
Novel melanocortin 4 receptor gene mutations in severely obese children
-
Lee YS, Poh LK, Kek BL, Loke KY. Novel melanocortin 4 receptor gene mutations in severely obese children. Clin Endocrinol (Oxf) 2008; 68:529-535.
-
(2008)
Clin Endocrinol (Oxf)
, vol.68
, pp. 529-535
-
-
Lee, Y.S.1
Poh, L.K.2
Kek, B.L.3
Loke, K.Y.4
-
53
-
-
84861982757
-
Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery
-
Hatoum IJ, Stylopoulos N, Vanhoose AM, et al. Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. J Clin Endocrinol Metab 2012; 97:E1023-1031.
-
(2012)
J Clin Endocrinol Metab
, vol.97
-
-
Hatoum, I.J.1
Stylopoulos, N.2
Vanhoose, A.M.3
-
54
-
-
84888082251
-
Weight loss after bariatric surgery in morbidly obese adolescents with MC4R mutations
-
Censani M, Conroy R, Deng L, et al. Weight loss after bariatric surgery in morbidly obese adolescents with MC4R mutations. Obesity (Silver Spring).2013
-
(2013)
Obesity (Silver Spring)
-
-
Censani, M.1
Conroy, R.2
Deng, L.3
-
55
-
-
84869816034
-
Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery
-
Valette M, Poitou C, Le Beyec J, et al. Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery. PloS One. 2012;7:e48221.
-
(2012)
PloS One
, vol.7
-
-
Valette, M.1
Poitou, C.2
Le Beyec, J.3
-
56
-
-
33646423288
-
Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany
-
Hinney A, Bettecken T, Tarnow P, et al. Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany. J Clin Endocrinol Metab 2006; 91:1761-1769.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1761-1769
-
-
Hinney, A.1
Bettecken, T.2
Tarnow, P.3
-
57
-
-
0015464898
-
Protein requirements of man: Variations in obligatory urinary and fecal nitrogen losses in young men
-
Scrimshaw NS, Hussein MA, Murray E, et al. Protein requirements of man: variations in obligatory urinary and fecal nitrogen losses in young men. J Nutr.1972;102:1595-1604.
-
(1972)
J Nutr
, vol.102
, pp. 1595-1604
-
-
Scrimshaw, N.S.1
Hussein, M.A.2
Murray, E.3
-
58
-
-
33745036725
-
Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist
-
Xiang Z, Litherland SA, Sorensen NB, et al. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist. Biochemistry 2006; 45:7277-7288.
-
(2006)
Biochemistry
, vol.45
, pp. 7277-7288
-
-
Xiang, Z.1
Litherland, S.A.2
Sorensen, N.B.3
-
59
-
-
34547839796
-
Nonsynonymous polymorphisms in melanocortin-4 receptor protect against obesity: The two facets of a Janus obesity gene
-
Stutzmann F, Vatin V, Cauchi S, et al. Nonsynonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene. Hum Mol Genet 2007; 16:1837-1844.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1837-1844
-
-
Stutzmann, F.1
Vatin, V.2
Cauchi, S.3
-
60
-
-
34547831224
-
The V103I polymorphism of the MC4R gene and obesity: Population based studies and meta-analysis of the MC4R gene and obesity: Population based studies and meta-analysis of 29 563 individuals
-
Young EH, Wareham NJ, Farooqi S, et al.The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals. Int J Obes (Lond).2007;31:1437-1441.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 1437-1441
-
-
Young, E.H.1
Wareham, N.J.2
Farooqi, S.3
-
61
-
-
77249140993
-
Association of the MC4R V103I polymorphism with obesity: A Chinese case-control study and meta-analysis in 55 195 individuals
-
Wang D, Ma J, Zhang S, et al. Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55 195 individuals. Obesity (Silver Spring) 2010; 18:573-579.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 573-579
-
-
Wang, D.1
Ma, J.2
Zhang, S.3
-
62
-
-
0027456619
-
Molecular cloning of a novel melanocortin receptor
-
Gantz I, Konda Y, Tashiro T, et al. Molecular cloning of a novel melanocortin receptor. J Biol Chem 1993; 268:8246-8250.
-
(1993)
J Biol Chem
, vol.268
, pp. 8246-8250
-
-
Gantz, I.1
Konda, Y.2
Tashiro, T.3
-
63
-
-
0027436690
-
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
Roselli-Rehfuss L, Mountjoy KG, Robbins LS, et al. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc Natl Acad Sci U S A 1993; 90: 8856-8860.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8856-8860
-
-
Roselli-Rehfuss, L.1
Mountjoy, K.G.2
Robbins, L.S.3
-
64
-
-
0033818103
-
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass
-
Chen AS, Marsh DJ, Trumbauer ME, et al. Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass.Nat Genet.2000;26:97-102
-
(2000)
Nat Genet
, vol.26
, pp. 97-102
-
-
Chen, A.S.1
Marsh, D.J.2
Trumbauer, M.E.3
-
65
-
-
0034456398
-
A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
-
Butler AA, Kesterson RA, Khong K, et al. A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse. Endocrinology.2000;141:3518-3521.
-
(2000)
Endocrinology
, vol.141
, pp. 3518-3521
-
-
Butler, A.A.1
Kesterson, R.A.2
Khong, K.3
-
66
-
-
84991847410
-
The role of melanocortin 3 receptor gene in childhood obesity
-
Lee YS, Poh LK, Kek BL, Loke KY. The role of melanocortin 3 receptor gene in childhood obesity. Diabetes 2007; 56:2622-2630.
-
(2007)
Diabetes
, vol.56
, pp. 2622-2630
-
-
Lee, Y.S.1
Poh, L.K.2
Kek, B.L.3
Loke, K.Y.4
-
67
-
-
78650553919
-
Rare melanocortin-3 receptor mutations with in vitro functional consequences are associated with human obesity
-
Mencarelli M, Dubern B, Alili R, et al. Rare melanocortin-3 receptor mutations with in vitro functional consequences are associated with human obesity. Hum Mol Genet 2011; 20:392-399.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 392-399
-
-
Mencarelli, M.1
Dubern, B.2
Alili, R.3
-
68
-
-
61849161252
-
Association of functionally significant melanocortin-4 but not melanocortin-3 receptor mutations with severe adult obesity in a large north american case-control study
-
Calton MA, Ersoy BA, Zhang S, et al. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum Mol Genet 2009;18:1140-1147.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1140-1147
-
-
Calton, M.A.1
Ersoy, B.A.2
Zhang, S.3
-
69
-
-
24144443764
-
Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity
-
Feng N, Young SF, Aguilera G, et al. Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity. Diabetes 2005; 54:2663-2667.
-
(2005)
Diabetes
, vol.54
, pp. 2663-2667
-
-
Feng, N.1
Young, S.F.2
Aguilera, G.3
-
70
-
-
70349785440
-
Energy intake and energy expenditure among children with polymorphisms of the melanocortin-3 receptor
-
Savastano DM, Tanofsky-Kraff M, Han JC, et al. Energy intake and energy expenditure among children with polymorphisms of the melanocortin-3 receptor. Am J Clin Nutr 2009; 90:912-920.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 912-920
-
-
Savastano, D.M.1
Tanofsky-Kraff, M.2
Han, J.C.3
-
71
-
-
84857398069
-
Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents
-
Santoro N, Zhang CK, Zhao H, et al. Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents. Hepatology 2012; 55:781-789.
-
(2012)
Hepatology
, vol.55
, pp. 781-789
-
-
Santoro, N.1
Zhang, C.K.2
Zhao, H.3
-
72
-
-
84876814186
-
The association between hepatic fat content and liver injury in obese children and adolescents: Effects of ethnicity, insulin resistance, and common gene variants
-
Santoro N, Feldstein AE, Enoksson E, et al. The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance, and common gene variants. Diabetes Care 2013;36:1353-1360
-
(2013)
Diabetes Care
, vol.36
, pp. 1353-1360
-
-
Santoro, N.1
Feldstein, A.E.2
Enoksson, E.3
-
73
-
-
79954421951
-
A common variant in the PNPLA3 gene is a risk factor for nonalcoholic fatty liver disease in obese Taiwanese children
-
Lin YC, Chang PF, Hu FC, et al. A common variant in the PNPLA3 gene is a risk factor for nonalcoholic fatty liver disease in obese Taiwanese children. J Pediatr 2011; 158:740-744.
-
(2011)
J Pediatr
, vol.158
, pp. 740-744
-
-
Lin, Y.C.1
Chang, P.F.2
Hu, F.C.3
-
74
-
-
84873378669
-
A common variant in the peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene is associated with nonalcoholic fatty liver disease in obese children
-
Lin YC, Chang PF, Chang MH, Ni YH. A common variant in the peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene is associated with nonalcoholic fatty liver disease in obese children. Am J Clin Nutr 2013;97:326-331
-
(2013)
Am J Clin Nutr
, vol.97
, pp. 326-331
-
-
Lin, Y.C.1
Chang, P.F.2
Chang, M.H.3
Ni, Y.H.4
-
75
-
-
84888124128
-
Visfatin and its genetic variants are associated with obesity-related morbidities and cardiometabolic risk in severely obese children
-
Ooi SQ, Chan RM, Poh LK, et al. Visfatin and its genetic variants are associated with obesity-related morbidities and cardiometabolic risk in severely obese children. Pediatr Obes 2013. [Epub ahead of print] Study about the discovery of susceptibility genetic variants to adverse cardiometabolic parameters in obese children.
-
(2013)
Pediatr Obes
-
-
Ooi, S.Q.1
Chan, R.M.2
Poh, L.K.3
|