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Volumn 74, Issue 12, 2013, Pages 879-889

Worldwide population variation and haplotype analysis at the serotonin transporter gene SLC6A4 and implications for association studies

Author keywords

Depression; genetics; haplotype; serotonin; serotonin transporter; SLC6A4

Indexed keywords

SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

EID: 84888017505     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.02.006     Document Type: Article
Times cited : (51)

References (38)
  • 1
    • 0027405191 scopus 로고
    • Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization
    • S. Ramamoorthy, A.L. Bauman, K.R. Moore, H. Han, T. Yang-Feng, and A.S. Chang Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization Proc Natl Acad Sci U S A 90 1993 2542 2546
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 2542-2546
    • Ramamoorthy, S.1    Bauman, A.L.2    Moore, K.R.3    Han, H.4    Yang-Feng, T.5    Chang, A.S.6
  • 3
    • 0033974338 scopus 로고    scopus 로고
    • The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants
    • M. Nakamura, S. Ueno, A. Sano, and H. Tanabe The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants Mol Psychiatry 5 2000 32 38
    • (2000) Mol Psychiatry , vol.5 , pp. 32-38
    • Nakamura, M.1    Ueno, S.2    Sano, A.3    Tanabe, H.4
  • 5
    • 0029939169 scopus 로고    scopus 로고
    • Polymorphism in serotonin transporter gene associated with susceptibility to major depression
    • A.D. Ogilvie, S. Battersby, V.J. Bubb, G. Fink, A.J. Harmar, and G.M. Goodwim Polymorphism in serotonin transporter gene associated with susceptibility to major depression Lancet 347 1996 731 733
    • (1996) Lancet , vol.347 , pp. 731-733
    • Ogilvie, A.D.1    Battersby, S.2    Bubb, V.J.3    Fink, G.4    Harmar, A.J.5    Goodwim, G.M.6
  • 7
    • 24044520963 scopus 로고    scopus 로고
    • Sequence analysis of the serotonin transporter and associations with antidepressant response
    • J.B. Kraft, S.L. Slager, P.J. McGrath, and S.P. Hamilton Sequence analysis of the serotonin transporter and associations with antidepressant response Biol Psychiatry 58 2005 374 381
    • (2005) Biol Psychiatry , vol.58 , pp. 374-381
    • Kraft, J.B.1    Slager, S.L.2    McGrath, P.J.3    Hamilton, S.P.4
  • 8
    • 30044439732 scopus 로고    scopus 로고
    • Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain
    • R.V. Parsey, R.S. Hastings, M.A. Oquendo, X. Hu, D. Goldman, and Y.Y. Huang Effect of a triallelic functional polymorphism of the serotonin- transporter-linked promoter region on expression of serotonin transporter in the human brain Am J Psychiatry 163 2006 48 51
    • (2006) Am J Psychiatry , vol.163 , pp. 48-51
    • Parsey, R.V.1    Hastings, R.S.2    Oquendo, M.A.3    Hu, X.4    Goldman, D.5    Huang, Y.Y.6
  • 9
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • X.Z. Hu, R.H. Lipsky, G. Zhu, L.A. Akhtar, J. Taubman, and B.D. Greenberg Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder Am J Hum Genet 78 2006 815 826
    • (2006) Am J Hum Genet , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3    Akhtar, L.A.4    Taubman, J.5    Greenberg, B.D.6
  • 10
  • 12
    • 51449089163 scopus 로고    scopus 로고
    • Autism and serotonin transporter gene polymorphisms: A systematic review and meta-analysis
    • C.H. Huang, and S.L. Santangelo Autism and serotonin transporter gene polymorphisms: A systematic review and meta-analysis Am J Med Genet B Neuropsychiatr Genet 147B 2008 903 913
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 903-913
    • Huang, C.H.1    Santangelo, S.L.2
  • 13
    • 0041346384 scopus 로고    scopus 로고
    • A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders
    • M. Anguelova, C. Benkelfat, and G. Turecki A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders Mol Psychiatry 8 2003 574 591
    • (2003) Mol Psychiatry , vol.8 , pp. 574-591
    • Anguelova, M.1    Benkelfat, C.2    Turecki, G.3
  • 15
    • 0031423428 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms: Ethnic difference and possible association with bipolar affective disorder
    • H. Kunugi, M. Hattori, T. Kato, M. Tatsumi, T. Sakai, and T. Sasaki Serotonin transporter gene polymorphisms: Ethnic difference and possible association with bipolar affective disorder Mol Psychiatry 2 1997 457 462
    • (1997) Mol Psychiatry , vol.2 , pp. 457-462
    • Kunugi, H.1    Hattori, M.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Sasaki, T.6
  • 16
    • 84856214870 scopus 로고    scopus 로고
    • Identification and functional characterization of three novel alleles for the serotonin transporter-linked polymorphic region
    • E.A. Ehli, Y. Hu, T. Lengyel-Nelson, J.J. Hudziak, and G.E. Davies Identification and functional characterization of three novel alleles for the serotonin transporter-linked polymorphic region Mol Psychiatry 17 2012 185 192
    • (2012) Mol Psychiatry , vol.17 , pp. 185-192
    • Ehli, E.A.1    Hu, Y.2    Lengyel-Nelson, T.3    Hudziak, J.J.4    Davies, G.E.5
  • 17
    • 0034457001 scopus 로고    scopus 로고
    • A rare short allele of the serotonin transporter promoter region (5-HTTLPR) found in an aggressive schizophrenic patient of Jewish Libyan origin
    • A. Frisch, B. Finkel, E. Michaelovsky, M. Sigal, N. Laor, and R. Weizman A rare short allele of the serotonin transporter promoter region (5-HTTLPR) found in an aggressive schizophrenic patient of Jewish Libyan origin Psychiatr Genet 10 2000 179 183
    • (2000) Psychiatr Genet , vol.10 , pp. 179-183
    • Frisch, A.1    Finkel, B.2    Michaelovsky, E.3    Sigal, M.4    Laor, N.5    Weizman, R.6
  • 18
    • 78851471110 scopus 로고    scopus 로고
    • European Research Consortium for Suicide (EURECA) (2010): Rare genotype combination of the serotonin transporter gene associated with treatment response in severe personality disorder
    • Perroud N, Salzmann A, Saiz PA, Baca-Garcia E, Sarchiapone M, Garcia-Portilla MP, et al.; European Research Consortium for Suicide (EURECA) (2010): Rare genotype combination of the serotonin transporter gene associated with treatment response in severe personality disorder. Am J Med Genet B Neuropsychiatr Genet 153B:1494-1497.
    • Am J Med Genet B Neuropsychiatr Genet , vol.153 , pp. 1494-1497
    • Perroud, N.1    Salzmann, A.2    Saiz, P.A.3    Baca-Garcia, E.4    Sarchiapone, M.5    Garcia-Portilla, M.P.6
  • 19
    • 22544446444 scopus 로고    scopus 로고
    • Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors
    • J.S. Sutcliffe, R.J. Delahanty, H.C. Prasad, J.L. McCauley, Q. Han, and L. Jiang Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors Am J Hum Genet 77 2005 265 279
    • (2005) Am J Hum Genet , vol.77 , pp. 265-279
    • Sutcliffe, J.S.1    Delahanty, R.J.2    Prasad, H.C.3    McCauley, J.L.4    Han, Q.5    Jiang, L.6
  • 20
    • 23844454012 scopus 로고    scopus 로고
    • Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase
    • H.C. Prasad, C.B. Zhu, J.L. McCauley, D.J. Samuvel, S. Ramamoorthy, and R.C. Shelton Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase Proc Natl Acad Sci U S A 102 2005 11545 11550
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11545-11550
    • Prasad, H.C.1    Zhu, C.B.2    McCauley, J.L.3    Samuvel, D.J.4    Ramamoorthy, S.5    Shelton, R.C.6
  • 21
  • 22
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • M. Stephens, N.J. Smith, and P. Donnelly A new statistical method for haplotype reconstruction from population data Am J Hum Genet 68 2001 978 989
    • (2001) Am J Hum Genet , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 23
    • 13844270527 scopus 로고    scopus 로고
    • Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation
    • M. Stephens, and P. Scheet Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation Am J Hum Genet 76 2005 449 462
    • (2005) Am J Hum Genet , vol.76 , pp. 449-462
    • Stephens, M.1    Scheet, P.2
  • 24
    • 27544435123 scopus 로고    scopus 로고
    • HAPLOT: A graphical comparison of haplotype blocks, tagSNP sets and SNP variation for multiple populations
    • S. Gu, A.J. Pakstis, and K.K. Kidd HAPLOT: a graphical comparison of haplotype blocks, tagSNP sets and SNP variation for multiple populations Bioinformatics 21 2005 3938 3939
    • (2005) Bioinformatics , vol.21 , pp. 3938-3939
    • Gu, S.1    Pakstis, A.J.2    Kidd, K.K.3
  • 28
    • 0035377613 scopus 로고    scopus 로고
    • Identification of an additional allelic variant (XLS) of the human serotonin transporter gene (SLC6A4): -1201Cins66
    • S.J. Delbrück, K.K. Kidd, and M.R. Hoehe Identification of an additional allelic variant (XLS) of the human serotonin transporter gene (SLC6A4): -1201Cins66 Hum Mutat 17 2001 524
    • (2001) Hum Mutat , vol.17 , pp. 524
    • Delbrück, S.J.1    Kidd, K.K.2    Hoehe, M.R.3
  • 29
    • 0032841176 scopus 로고    scopus 로고
    • An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells
    • C.E. Fiskerstrand, E.A. Lovejoy, and J.P. Quinn An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells FEBS Lett 458 1999 171 174
    • (1999) FEBS Lett , vol.458 , pp. 171-174
    • Fiskerstrand, C.E.1    Lovejoy, E.A.2    Quinn, J.P.3
  • 32
    • 79952012111 scopus 로고    scopus 로고
    • Looking on the bright side of serotonin transporter gene variation
    • J.R. Homberg, and K.P. Lesch Looking on the bright side of serotonin transporter gene variation Biol Psychiatry 69 2011 513 519
    • (2011) Biol Psychiatry , vol.69 , pp. 513-519
    • Homberg, J.R.1    Lesch, K.P.2
  • 34
    • 54249117763 scopus 로고    scopus 로고
    • A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk
    • L.J. Chin, E. Ratner, S. Leng, R. Zhai, S. Nallur, and I. Babar A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk Cancer Res 68 2008 8535 8540
    • (2008) Cancer Res , vol.68 , pp. 8535-8540
    • Chin, L.J.1    Ratner, E.2    Leng, S.3    Zhai, R.4    Nallur, S.5    Babar, I.6
  • 35
    • 33745599585 scopus 로고    scopus 로고
    • Allelic expression of serotonin transporter (SERT) mRNA in human pons: Lack of correlation 2 with the polymorphism SERTLPR
    • J.E. Lim, A. Papp, J. Pinsonneault, W. Sadée, and D. Saffen Allelic expression of serotonin transporter (SERT) mRNA in human pons: Lack of correlation 2 with the polymorphism SERTLPR Mol Psychiatry 11 2006 649 662
    • (2006) Mol Psychiatry , vol.11 , pp. 649-662
    • Lim, J.E.1    Papp, A.2    Pinsonneault, J.3    Sadée, W.4    Saffen, D.5
  • 36
    • 84863455522 scopus 로고    scopus 로고
    • Prediction of serotonin transporter promoter polymorphism genotypes from single nucleotide polymorphism arrays using machine learning methods
    • A.T. Lu, S. Bakker, E. Janson, S. Cichon, R.M. Cantor, and R.A. Ophoff Prediction of serotonin transporter promoter polymorphism genotypes from single nucleotide polymorphism arrays using machine learning methods Psychiatr Genet 22 2012 182 188
    • (2012) Psychiatr Genet , vol.22 , pp. 182-188
    • Lu, A.T.1    Bakker, S.2    Janson, E.3    Cichon, S.4    Cantor, R.M.5    Ophoff, R.A.6
  • 38
    • 84876724772 scopus 로고    scopus 로고
    • Gene: SLC6A4. 1000 Genomes Accessed February 27
    • Gene: SLC6A4. 1000 Genomes. A Deep Catalog of Human Genetic Variation. Available at: http://browser.1000genomes.org/Homo-sapiens/Gene/Variation-Gene/ Table?db=core;g=ENSG00000108576;r=17:28521337-28562954#ALL. Accessed February 27, 2013.
    • (2013) A Deep Catalog of Human Genetic Variation


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