Gestational hypoxia induces sex-differential methylation of Crhr1 linked to anxiety-like behavior

Molecular Neurobiology

Volumn 48, Issue 3, 2013, Pages 544-555

  Wang, Xi ^a   Meng, Fan Sen ^a   Liu, Zong Yun ^b   Fan, Jun Ming ^a   Hao, Ke ^a   Chen, Xue Qun ^a,b,c   Du, Ji Zeng ^a,b,c  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BEIJING HOSPITAL   (China)

^c Key Lab Bioinfo Zhejiang Prov   (China)

Author keywords

Anxiety like behavior; Corticotropin releasing hormone receptor 1; DNA methylation; Gestation; Hypoxia

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; DNA METHYLTRANSFERASE 3B; MESSENGER RNA;

ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; BRAIN TISSUE; CONTROLLED STUDY; CPG ISLAND; CRHR1 GENE; DEMETHYLATION; DNA METHYLATION; DNA MODIFICATION; EMBRYO; EPIGENETICS; FEMALE; GENE; GENE ACTIVATION; GENETIC TRANSFECTION; GESTATIONAL INTERMITTENT HYPOXIA; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; HYPOXIA; MALE; MAZE TEST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENATAL STRESS; PROGENY; PROMOTER REGION; RAT; REVIEW; SEX DIFFERENCE;

AMYGDALA; ANIMALS; ANOXIA; ANXIETY; BEHAVIOR, ANIMAL; CORTICOTROPIN-RELEASING HORMONE; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA MUTATIONAL ANALYSIS; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LUCIFERASES; MALE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PREGNANCY; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RNA, MESSENGER; SEX CHARACTERISTICS;

EID: 84888011462     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8444-4     Document Type: Review

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