-
2
-
-
84865274411
-
The neurobiology of sirtuins and their role in neurodegeneration
-
22749331 1:CAS:528:DC%2BC38XpsVOktrk%3D
-
Donmez G (2012) The neurobiology of sirtuins and their role in neurodegeneration. Trends Pharmacol Sci 33(9):494-501
-
(2012)
Trends Pharmacol Sci
, vol.33
, Issue.9
, pp. 494-501
-
-
Donmez, G.1
-
3
-
-
84863714863
-
Dietary polyphenols as modulators of brain functions: Biological actions and molecular mechanisms underpinning their beneficial effects
-
22701758
-
Vauzour D (2012) Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. Oxid Med Cell Longev 2012:914273
-
(2012)
Oxid Med Cell Longev.
, vol.2012
, pp. 914273
-
-
Vauzour, D.1
-
4
-
-
77955707062
-
Potential role of sirtuin as a therapeutic target for neurodegenerative diseases
-
19826562
-
Han SH (2009) Potential role of sirtuin as a therapeutic target for neurodegenerative diseases. J Clin Neurol 5(3):120-125
-
(2009)
J Clin Neurol.
, vol.5
, Issue.3
, pp. 120-125
-
-
Han, S.H.1
-
5
-
-
0031916984
-
The free radical theory of aging matures
-
9562038 1:CAS:528:DyaK1cXislakurg%3D
-
Beckman KB, Ames BN (1998) The free radical theory of aging matures. Physiol Rev 78(2):547-581
-
(1998)
Physiol Rev
, vol.78
, Issue.2
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
6
-
-
77955088481
-
Resveratrol as a therapeutic agent for neurodegenerative diseases
-
20306310 1:CAS:528:DC%2BC3cXmsFSru7c%3D
-
Sun AY, Wang Q, Simonyi A, Sun GY (2010) Resveratrol as a therapeutic agent for neurodegenerative diseases. Mol Neurobiol 41(2-3):375-383
-
(2010)
Mol Neurobiol
, vol.41
, Issue.2-3
, pp. 375-383
-
-
Sun, A.Y.1
Wang, Q.2
Simonyi, A.3
Sun, G.Y.4
-
7
-
-
0035077448
-
Problems of cell death in neurodegeneration and Alzheimer's disease
-
12214070 1:CAS:528:DC%2BD3MXjs1eju7g%3D
-
Jellinger KA, Stadelmann C (2001) Problems of cell death in neurodegeneration and Alzheimer's disease. J Alzheimers Dis 3(1):31-40
-
(2001)
J Alzheimers Dis.
, vol.3
, Issue.1
, pp. 31-40
-
-
Jellinger, K.A.1
Stadelmann, C.2
-
8
-
-
26844449402
-
Transgenic models of Alzheimer's disease: Learning from animals
-
16389306
-
Spires TL, Hyman BT (2005) Transgenic models of Alzheimer's disease: learning from animals. NeuroRx 2(3):423-437
-
(2005)
NeuroRx
, vol.2
, Issue.3
, pp. 423-437
-
-
Spires, T.L.1
Hyman, B.T.2
-
9
-
-
0023340731
-
Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
-
3297920 1:STN:280:DyaL2s3kvVSnsw%3D%3D
-
Rine J, Herskowitz I (1987) Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116(1):9-22
-
(1987)
Genetics
, vol.116
, Issue.1
, pp. 9-22
-
-
Rine, J.1
Herskowitz, I.2
-
10
-
-
77957975705
-
A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: Part 1
-
21155626
-
Kelly G (2010) A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1. Altern Med Rev 15(3):245-263
-
(2010)
Altern Med Rev.
, vol.15
, Issue.3
, pp. 245-263
-
-
Kelly, G.1
-
11
-
-
77957975705
-
A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: Part 2
-
21194247
-
Kelly GS (2010) A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 2. Altern Med Rev 15(4):313-328
-
(2010)
Altern Med Rev.
, vol.15
, Issue.4
, pp. 313-328
-
-
Kelly, G.S.1
-
12
-
-
33644875954
-
Neuronal protection by sirtuins in Alzheimer's disease
-
16219030 1:CAS:528:DC%2BD28XntVSjsg%3D%3D
-
Anekonda TS, Reddy PH (2006) Neuronal protection by sirtuins in Alzheimer's disease. J Neurochem 96(2):305-313
-
(2006)
J Neurochem
, vol.96
, Issue.2
, pp. 305-313
-
-
Anekonda, T.S.1
Reddy, P.H.2
-
13
-
-
41749088686
-
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases
-
1:CAS:528:DC%2BD1cXitF2ku78%3D
-
Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA et al (2007) Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS NeurolDisord Drug Targets 6(6):411-423
-
(2007)
CNS NeurolDisord Drug Targets
, vol.6
, Issue.6
, pp. 411-423
-
-
Nunomura, A.1
Moreira, P.I.2
Lee, H.G.3
Zhu, X.4
Castellani, R.J.5
Smith, M.A.6
-
14
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
10873683 1:CAS:528:DC%2BD3cXkt1Kmurg%3D
-
Frye RA (2000) Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273(2):793-798
-
(2000)
Biochem Biophys Res Commun
, vol.273
, Issue.2
, pp. 793-798
-
-
Frye, R.A.1
-
15
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
17447894 1:CAS:528:DC%2BD2sXks1ansr4%3D
-
Michan S, Sinclair D (2007) Sirtuins in mammals: insights into their biological function. Biochem J 404(1):1-13
-
(2007)
Biochem J
, vol.404
, Issue.1
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
16
-
-
77953166978
-
Distribution analysis of deacetylase SIRT1 in rodent and human nervous systems
-
20225204 1:CAS:528:DC%2BC3cXosFemtrY%3D
-
Zakhary SM, Ayubcha D, Dileo JN, Jose R, Leheste JR, Horowitz JM et al (2010) Distribution analysis of deacetylase SIRT1 in rodent and human nervous systems. Anat Rec (Hoboken) 293(6):1024-1032
-
(2010)
Anat Rec (Hoboken).
, vol.293
, Issue.6
, pp. 1024-1032
-
-
Zakhary, S.M.1
Ayubcha, D.2
Dileo, J.N.3
Jose, R.4
Leheste, J.R.5
Horowitz, J.M.6
-
17
-
-
79955661471
-
Mammalian Sirt1: Insights on its biological functions
-
21549004 1:CAS:528:DC%2BC3MXmsV2gsrg%3D
-
Rahman S, Islam R (2011) Mammalian Sirt1: insights on its biological functions. Cell Commun Signal 9:11
-
(2011)
Cell Commun Signal.
, vol.9
, pp. 11
-
-
Rahman, S.1
Islam, R.2
-
18
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
10693811 1:CAS:528:DC%2BD3cXhsVWiurY%3D
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403(6771):795-800
-
(2000)
Nature
, vol.403
, Issue.6771
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
19
-
-
16844385222
-
Sirtuins for healthy neurons
-
15800644 1:CAS:528:DC%2BD2MXislCmt7s%3D
-
Sinclair D (2005) Sirtuins for healthy neurons. Nat Genet 37(4):339-340
-
(2005)
Nat Genet
, vol.37
, Issue.4
, pp. 339-340
-
-
Sinclair, D.1
-
20
-
-
0346094379
-
Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain
-
14706864 1:CAS:528:DC%2BD2cXovVWg
-
Sakamoto J, Miura T, Shimamoto K, Horio Y (2004) Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett 556(1-3):281-286
-
(2004)
FEBS Lett
, vol.556
, Issue.1-3
, pp. 281-286
-
-
Sakamoto, J.1
Miura, T.2
Shimamoto, K.3
Horio, Y.4
-
21
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
16079181 1:CAS:528:DC%2BD2MXhtVygtL%2FP
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I (2005) Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16(10):4623-4635
-
(2005)
Mol Biol Cell.
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
22
-
-
84859367098
-
Circadian rhythms and memory formation: Regulation by chromatin remodeling
-
22470318 1:CAS:528:DC%2BC38XmtlajurY%3D
-
Sahar S, Sassone-Corsi P (2012) Circadian rhythms and memory formation: regulation by chromatin remodeling. Front Mol Neurosci 5:37
-
(2012)
Front Mol Neurosci
, vol.5
, pp. 37
-
-
Sahar, S.1
Sassone-Corsi, P.2
-
23
-
-
55749095213
-
Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
-
1:CAS:528:DC%2BD1cXht1GisbfI
-
Hisahara S, Chiba S, Matsumoto H, Tanno M, Yagi H, Shimohama S et al (2008) Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. Proc NatlAcadSci U S A 105(40):15599-15604
-
(2008)
Proc NatlAcadSci U S A.
, vol.105
, Issue.40
, pp. 15599-15604
-
-
Hisahara, S.1
Chiba, S.2
Matsumoto, H.3
Tanno, M.4
Yagi, H.5
Shimohama, S.6
-
24
-
-
54049158932
-
Brain SIRT1: Anatomical distribution and regulation by energy availability
-
18829956 1:CAS:528:DC%2BD1cXht1ChsLjF
-
Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J et al (2008) Brain SIRT1: anatomical distribution and regulation by energy availability. J Neurosci 28(40):9989-9996
-
(2008)
J Neurosci
, vol.28
, Issue.40
, pp. 9989-9996
-
-
Ramadori, G.1
Lee, C.E.2
Bookout, A.L.3
Lee, S.4
Williams, K.W.5
Anderson, J.6
-
25
-
-
47549109984
-
Beyond transcription factors: The role of chromatin modifying enzymes in regulating transcription required for memory
-
18583646 1:CAS:528:DC%2BD1MXhsV2ns70%3D
-
Barrett RM, Wood MA (2008) Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory. Learn Mem 15(7):460-467
-
(2008)
Learn Mem
, vol.15
, Issue.7
, pp. 460-467
-
-
Barrett, R.M.1
Wood, M.A.2
-
26
-
-
79953163655
-
Cognitive neuroepigenetics: A role for epigenetic mechanisms in learning and memory
-
21195202 1:CAS:528:DC%2BC3MXntlGmur0%3D
-
Day JJ, Sweatt JD (2011) Cognitive neuroepigenetics: a role for epigenetic mechanisms in learning and memory. Neurobiol Learn Mem 96(1):2-12
-
(2011)
Neurobiol Learn Mem
, vol.96
, Issue.1
, pp. 2-12
-
-
Day, J.J.1
Sweatt, J.D.2
-
27
-
-
77956649731
-
Joining the dots: From chromatin remodeling to neuronal plasticity
-
1:CAS:528:DC%2BC3cXhtFyiu7%2FL
-
Zocchi L, Sassone-Corsi P (2010) Joining the dots: from chromatin remodeling to neuronal plasticity. CurrOpinNeurobiol 20(4):432-440
-
(2010)
CurrOpinNeurobiol
, vol.20
, Issue.4
, pp. 432-440
-
-
Zocchi, L.1
Sassone-Corsi, P.2
-
28
-
-
41549136422
-
Paths of convergence: Sirtuins in aging and neurodegeneration
-
18400158 1:CAS:528:DC%2BD1cXltVOisrs%3D
-
Gan L, Mucke L (2008) Paths of convergence: sirtuins in aging and neurodegeneration. Neuron 58(1):10-14
-
(2008)
Neuron
, vol.58
, Issue.1
, pp. 10-14
-
-
Gan, L.1
Mucke, L.2
-
29
-
-
80054123174
-
Protective effects and mechanisms of sirtuins in the nervous system
-
1:CAS:528:DC%2BC3MXhsVSkt7rE
-
Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ et al (2011) Protective effects and mechanisms of sirtuins in the nervous system. ProgNeurobiol 95(3):373-395
-
(2011)
ProgNeurobiol
, vol.95
, Issue.3
, pp. 373-395
-
-
Zhang, F.1
Wang, S.2
Gan, L.3
Vosler, P.S.4
Gao, Y.5
Zigmond, M.J.6
-
30
-
-
45549096918
-
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
-
18590691
-
Li Y, Xu W, McBurney MW, Longo VD (2008) SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell Metab 8(1):38-48
-
(2008)
Cell Metab
, vol.8
, Issue.1
, pp. 38-48
-
-
Li, Y.1
Xu, W.2
McBurney, M.W.3
Longo, V.D.4
-
31
-
-
69949114938
-
Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats
-
19627456 1:CAS:528:DC%2BD1MXht1Squ7nK
-
Chang HM, Wu UI, Lan CT (2009) Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats. J Pineal Res 47(3):211-220
-
(2009)
J Pineal Res
, vol.47
, Issue.3
, pp. 211-220
-
-
Chang, H.M.1
Wu, U.I.2
Lan, C.T.3
-
32
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
11672522 1:CAS:528:DC%2BD3MXotVSntro%3D
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A et al (2001) Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107(2):137-148
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
-
33
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
-
15716268 1:CAS:528:DC%2BD2MXjtleiu7Y%3D
-
Nemoto S, Fergusson MM, Finkel T (2005) SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J Biol Chem 280(16):16456-16460
-
(2005)
J Biol Chem
, vol.280
, Issue.16
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
34
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
17936707
-
Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L (2007) SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell 28(1):91-106
-
(2007)
Mol Cell.
, vol.28
, Issue.1
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Tse, J.G.4
Krieger, M.5
Guarente, L.6
-
35
-
-
84855428749
-
Translating cell survival and cell longevity into treatment strategies with SIRT1
-
1:STN:280:DC%2BC387gsVGntQ%3D%3D
-
Maiese K, Chong ZZ, Shang YC, Wang S (2011) Translating cell survival and cell longevity into treatment strategies with SIRT1. Rom J MorpholEmbryol 52(4):1173-1185
-
(2011)
Rom J MorpholEmbryol.
, vol.52
, Issue.4
, pp. 1173-1185
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
Wang, S.4
-
36
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
11672523 1:CAS:528:DC%2BD3MXotVSntrs%3D
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK et al (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107(2):149-159
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
-
37
-
-
24344509883
-
The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammals
-
15964060 1:CAS:528:DC%2BD2MXpvFeit74%3D
-
Lemieux ME, Yang X, Jardine K, He X, Jacobsen KX, Staines WA et al (2005) The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammals. Mech Ageing Dev 126(10):1097-1105
-
(2005)
Mech Ageing Dev
, vol.126
, Issue.10
, pp. 1097-1105
-
-
Lemieux, M.E.1
Yang, X.2
Jardine, K.3
He, X.4
Jacobsen, K.X.5
Staines, W.A.6
-
38
-
-
45849137875
-
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts
-
18320031
-
Huang J, Gan Q, Han L, Li J, Zhang H, Sun Y et al (2008) SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. PLoS One 3(3):e1710
-
(2008)
PLoS One
, vol.3
, Issue.3
, pp. 1710
-
-
Huang, J.1
Gan, Q.2
Han, L.3
Li, J.4
Zhang, H.5
Sun, Y.6
-
39
-
-
36348974168
-
The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation
-
17901049 1:CAS:528:DC%2BD2sXhtlSltrfI
-
Zhang J (2007) The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. J Biol Chem 282(47):34356-34364
-
(2007)
J Biol Chem
, vol.282
, Issue.47
, pp. 34356-34364
-
-
Zhang, J.1
-
40
-
-
3042631024
-
Gene regulation and DNA damage in the ageing human brain
-
15190254 1:CAS:528:DC%2BD2cXltVKltLY%3D
-
Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J et al (2004) Gene regulation and DNA damage in the ageing human brain. Nature 429(6994):883-891
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 883-891
-
-
Lu, T.1
Pan, Y.2
Kao, S.Y.3
Li, C.4
Kohane, I.5
Chan, J.6
-
41
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
12524534 1:CAS:528:DC%2BD3sXotlSgsw%3D%3D
-
Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P (2003) Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 9(2):213-219
-
(2003)
Nat Med
, vol.9
, Issue.2
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
42
-
-
0042346382
-
Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion
-
12754201 1:CAS:528:DC%2BD3sXlsFKktL4%3D
-
Sun Y, Yao J, Kim TW, Tall AR (2003) Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion. J Biol Chem 278(30):27688-27694
-
(2003)
J Biol Chem
, vol.278
, Issue.30
, pp. 27688-27694
-
-
Sun, Y.1
Yao, J.2
Kim, T.W.3
Tall, A.R.4
-
43
-
-
34547531201
-
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors
-
1:CAS:528:DC%2BD2sXnt1Oisrs%3D
-
Zelcer N, Khanlou N, Clare R, Jiang Q, Reed-Geaghan EG, Landreth GE et al (2007) Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc NatlAcadSci U S A 104(25):10601-10606
-
(2007)
Proc NatlAcadSci U S A
, vol.104
, Issue.25
, pp. 10601-10606
-
-
Zelcer, N.1
Khanlou, N.2
Clare, R.3
Jiang, Q.4
Reed-Geaghan, E.G.5
Landreth, G.E.6
-
44
-
-
14044277556
-
Redox regulation of NF-kappaB activation: Distinct redox regulation between the cytoplasm and the nucleus
-
15706086 1:CAS:528:DC%2BD2MXht1agsb8%3D
-
Kabe Y, Ando K, Hirao S, Yoshida M, Handa H (2005) Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus. Antioxid Redox Signal 7(3-4):395-403
-
(2005)
Antioxid Redox Signal
, vol.7
, Issue.3-4
, pp. 395-403
-
-
Kabe, Y.1
Ando, K.2
Hirao, S.3
Yoshida, M.4
Handa, H.5
-
45
-
-
33646010041
-
Roles for NF-kappaB in nerve cell survival, plasticity, and disease
-
16397579 1:CAS:528:DC%2BD28XjsFWisLc%3D
-
Mattson MP, Meffert MK (2006) Roles for NF-kappaB in nerve cell survival, plasticity, and disease. Cell Death Differ 13(5):852-860
-
(2006)
Cell Death Differ
, vol.13
, Issue.5
, pp. 852-860
-
-
Mattson, M.P.1
Meffert, M.K.2
-
46
-
-
0035845492
-
Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice
-
1:CAS:528:DC%2BD3MXntVGnu70%3D
-
Cao SX, Dhahbi JM, Mote PL, Spindler SR (2001) Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice. Proc NatlAcadSci U S A 98(19):10630-10635
-
(2001)
Proc NatlAcadSci U S A
, vol.98
, Issue.19
, pp. 10630-10635
-
-
Cao, S.X.1
Dhahbi, J.M.2
Mote, P.L.3
Spindler, S.R.4
-
47
-
-
0036752830
-
Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: Modification by genes, diet and behavior
-
12392775 1:CAS:528:DC%2BD38XotVCitbw%3D
-
Mattson MP, Duan W, Chan SL, Cheng A, Haughey N, Gary DS et al (2002) Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior. Neurobiol Aging 23(5):695-705
-
(2002)
Neurobiol Aging
, vol.23
, Issue.5
, pp. 695-705
-
-
Mattson, M.P.1
Duan, W.2
Chan, S.L.3
Cheng, A.4
Haughey, N.5
Gary, D.S.6
-
48
-
-
11144243412
-
Modulation of neurodegeneration by molecular chaperones
-
15611723 1:CAS:528:DC%2BD2cXhtVyqt77N
-
Muchowski PJ, Wacker JL (2005) Modulation of neurodegeneration by molecular chaperones. Nat Rev Neurosci 6(1):11-22
-
(2005)
Nat Rev Neurosci
, vol.6
, Issue.1
, pp. 11-22
-
-
Muchowski, P.J.1
Wacker, J.L.2
-
49
-
-
77953667076
-
Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms
-
20049741
-
Van Ham TJ, Breitling R, Swertz MA, Nollen EA (2009) Neurodegenerative diseases: lessons from genome-wide screens in small model organisms. EMBO Mol Med 1:360-370
-
(2009)
EMBO Mol Med
, vol.1
, pp. 360-370
-
-
Van Ham, T.J.1
Breitling, R.2
Swertz, M.A.3
Nollen, E.A.4
-
50
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
12130773 1:CAS:528:DC%2BD38Xls1Cju7s%3D
-
Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297(5580):353-356
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
51
-
-
0035081475
-
Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
-
12214075 1:CAS:528:DC%2BD3MXjs1eisr4%3D
-
Selkoe DJ (2001) Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J Alzheimers Dis 3:75-80
-
(2001)
J Alzheimers Dis
, vol.3
, pp. 75-80
-
-
Selkoe, D.J.1
-
52
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
15734686 1:CAS:528:DC%2BD2MXitVWnu7k%3D
-
Tanzi RE, Bertram L (2005) Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120:545-555
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
53
-
-
34248190279
-
A beta oligomers - A decade of discovery
-
17286590 1:CAS:528:DC%2BD2sXmsFensrc%3D
-
Walsh DM, Selkoe DJ (2007) A beta oligomers - a decade of discovery. J Neurochem 101:1172-1184
-
(2007)
J Neurochem
, vol.101
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
54
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
15734681 1:CAS:528:DC%2BD2MXitVWnurg%3D
-
Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120(4):483-495
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
55
-
-
25444474703
-
Mitochondria take center stage in aging and neurodegeneration
-
16178023 1:CAS:528:DC%2BD2MXhtFGrs7fE
-
Beal MF (2005) Mitochondria take center stage in aging and neurodegeneration. Ann Neurol 58(4):495-505
-
(2005)
Ann Neurol
, vol.58
, Issue.4
, pp. 495-505
-
-
Beal, M.F.1
-
56
-
-
23244435445
-
The alpha-ketoglutarate-dehydrogenase complex: A mediator between mitochondria and oxidative stress in neurodegeneration
-
15953811 1:CAS:528:DC%2BD2MXmtFKltb4%3D
-
Gibson GE, Blass JP, Beal MF, Bunik V (2005) The alpha-ketoglutarate- dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration. Mol Neurobiol 31(1-3):43-63
-
(2005)
Mol Neurobiol
, vol.31
, Issue.1-3
, pp. 43-63
-
-
Gibson, G.E.1
Blass, J.P.2
Beal, M.F.3
Bunik, V.4
-
57
-
-
84880190006
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism: A reprise
-
16914855 1:CAS:528:DC%2BD28XotFKksbY%3D
-
Selkoe DJ (2006) Amyloid beta-peptide is produced by cultured cells during normal metabolism: a reprise. J Alzheimers Dis 9(3 Suppl):163-168
-
(2006)
J Alzheimers Dis
, vol.9
, Issue.3 SUPPL.
, pp. 163-168
-
-
Selkoe, D.J.1
-
58
-
-
0347506014
-
Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease
-
14657791
-
Gandy S, Martins RN, Buxbaum J (2003) Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease. Alzheimer Dis Assoc Disord 17(4):259-266
-
(2003)
Alzheimer Dis Assoc Disord
, vol.17
, Issue.4
, pp. 259-266
-
-
Gandy, S.1
Martins, R.N.2
Buxbaum, J.3
-
59
-
-
0036403702
-
Deciphering the genetic basis of Alzheimer's disease
-
12142353 1:CAS:528:DC%2BD3sXktlCktg%3D%3D
-
Selkoe DJ, Podlisny MB (2002) Deciphering the genetic basis of Alzheimer's disease. Annu Rev Genomics Hum Genet 3:67-99
-
(2002)
Annu Rev Genomics Hum Genet
, vol.3
, pp. 67-99
-
-
Selkoe, D.J.1
Podlisny, M.B.2
-
60
-
-
24144468208
-
ADAM proteases: Protective role in Alzheimer's and prion diseases?
-
15975064 1:CAS:528:DC%2BD2cXlslWkt70%3D
-
Vincent B (2004) ADAM proteases: protective role in Alzheimer's and prion diseases? Curr Alzheimer Res 1(3):165-174
-
(2004)
Curr Alzheimer Res
, vol.1
, Issue.3
, pp. 165-174
-
-
Vincent, B.1
-
61
-
-
0033616716
-
Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
-
1:CAS:528:DyaK1MXjslChsLY%3D
-
Lammich S, Kojro E, Postina R, Gilbert S, Pfeiffer R, Jasionowski M et al (1999) Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease. Proc NatlAcadSci U S A 96(7):3922-3927
-
(1999)
Proc NatlAcadSci U S A
, vol.96
, Issue.7
, pp. 3922-3927
-
-
Lammich, S.1
Kojro, E.2
Postina, R.3
Gilbert, S.4
Pfeiffer, R.5
Jasionowski, M.6
-
62
-
-
0028178837
-
Beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: Implications to Alzheimer's disease
-
8179604 1:CAS:528:DyaK2cXivFGrtL8%3D
-
Butterfield DA, Hensley K, Harris M, Mattson M, Carney J (1994) beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem Biophys Res Commun 200(2):710-715
-
(1994)
Biochem Biophys Res Commun
, vol.200
, Issue.2
, pp. 710-715
-
-
Butterfield, D.A.1
Hensley, K.2
Harris, M.3
Mattson, M.4
Carney, J.5
-
63
-
-
0028180518
-
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
-
1:CAS:528:DyaK2cXivFGrt7s%3D
-
Hensley K, Carney JM, Mattson MP, Aksenova M, Harris M, Wu JF et al (1994) A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc NatlAcadSci U S A 91(8):3270-3274
-
(1994)
Proc NatlAcadSci U S A
, vol.91
, Issue.8
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
-
64
-
-
0033601338
-
Cu(II) potentiation of Alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction
-
10601271 1:CAS:528:DC%2BD3cXpsFSi
-
Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR et al (1999) Cu(II) potentiation of Alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. J Biol Chem 274(52):37111-37116
-
(1999)
J Biol Chem
, vol.274
, Issue.52
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
Hartshorn, M.A.4
Tyndall, J.D.5
Hanson, G.R.6
-
65
-
-
0029610011
-
The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
-
8866675 1:STN:280:DyaK2s%2FitVaqsg%3D%3D
-
McGeer PL, McGeer EG (1995) The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Brain Res Rev 21(2):195-218
-
(1995)
Brain Res Brain Res Rev
, vol.21
, Issue.2
, pp. 195-218
-
-
McGeer, P.L.1
McGeer, E.G.2
-
66
-
-
0242268945
-
Immunotherapeutic approaches to Alzheimer's disease
-
14593170 1:CAS:528:DC%2BD3sXos1Cmt7g%3D
-
Monsonego A, Weiner HL (2003) Immunotherapeutic approaches to Alzheimer's disease. Science 302(5646):834-838
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 834-838
-
-
Monsonego, A.1
Weiner, H.L.2
-
67
-
-
33846959101
-
Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in squirrel monkeys (Saimiri sciureus)
-
17183154 1:CAS:528:DC%2BD28Xhtlansr7K
-
Qin W, Chachich M, Lane M, Roth G, Bryant M, de Cabo R et al (2006) Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in squirrel monkeys (Saimiri sciureus). J Alzheimers Dis 10(4):417-422
-
(2006)
J Alzheimers Dis
, vol.10
, Issue.4
, pp. 417-422
-
-
Qin, W.1
Chachich, M.2
Lane, M.3
Roth, G.4
Bryant, M.5
De Cabo, R.6
-
68
-
-
41549138483
-
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
1:CAS:528:DC%2BD1cXjtlKkt78%3D
-
Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE et al (2008) A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc NatlAcadSci U S A 105(9):3374-3379
-
(2008)
Proc NatlAcadSci U S A
, vol.105
, Issue.9
, pp. 3374-3379
-
-
Lee, I.H.1
Cao, L.2
Mostoslavsky, R.3
Lombard, D.B.4
Liu, J.5
Bruns, N.E.6
-
69
-
-
52249112474
-
Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-beta peptide (1-42)
-
1:CAS:528:DC%2BD1cXhtFersb7P
-
Qin Z, Sun Z, Huang J, Hu Y, Wu Z, Mei B (2008) Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-beta peptide (1-42). NeurosciLett 444(3):217-221
-
(2008)
NeurosciLett
, vol.444
, Issue.3
, pp. 217-221
-
-
Qin, Z.1
Sun, Z.2
Huang, J.3
Hu, Y.4
Wu, Z.5
Mei, B.6
-
70
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
15310905 1:CAS:528:DC%2BD2cXmsVGmsbc%3D
-
Araki T, Sasaki Y, Milbrandt J (2004) Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305(5686):1010-1013
-
(2004)
Science
, vol.305
, Issue.5686
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
71
-
-
4243098426
-
Neuroscience. NAD to the rescue
-
15310883 1:CAS:528:DC%2BD2cXmslWqsLk%3D
-
Bedalov A, Simon JA (2004) Neuroscience. NAD to the rescue. Science 305(5686):954-955
-
(2004)
Science
, vol.305
, Issue.5686
, pp. 954-955
-
-
Bedalov, A.1
Simon, J.A.2
-
72
-
-
14644421534
-
Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models
-
15748777 1:CAS:528:DC%2BD2MXhvVektbw%3D
-
Patel NV, Gordon MN, Connor KE, Good RA, Engelman RW, Mason J et al (2005) Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiol Aging 26(7):995-1000
-
(2005)
Neurobiol Aging
, vol.26
, Issue.7
, pp. 995-1000
-
-
Patel, N.V.1
Gordon, M.N.2
Connor, K.E.3
Good, R.A.4
Engelman, R.W.5
Mason, J.6
-
73
-
-
20144386977
-
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
-
15650008
-
Wang J, Ho L, Qin W, Rocher AB, Seror I, Humala N et al (2005) Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J 19(6):659-661
-
(2005)
FASEB J
, vol.19
, Issue.6
, pp. 659-661
-
-
Wang, J.1
Ho, L.2
Qin, W.3
Rocher, A.B.4
Seror, I.5
Humala, N.6
-
74
-
-
0033566286
-
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
-
10398297 1:CAS:528:DyaK1MXksFSntL4%3D
-
Duan W, Mattson MP (1999) Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J Neurosci Res 57:195-206
-
(1999)
J Neurosci Res
, vol.57
, pp. 195-206
-
-
Duan, W.1
Mattson, M.P.2
-
75
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
-
16183991 1:CAS:528:DC%2BD2MXht1Gjs7vF
-
Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S et al (2005) SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J Biol Chem 280(48):40364-40374
-
(2005)
J Biol Chem
, vol.280
, Issue.48
, pp. 40364-40374
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.F.4
Kwon, H.5
Yi, S.6
-
76
-
-
33645461302
-
NF-kappaB pathway: A target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production
-
16623827
-
Valerio A, Boroni F, Benarese M, Sarnico I, Ghisi V, Bresciani LG et al (2006) NF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production. Eur J Neurosci 23(7):1711-1720
-
(2006)
Eur J Neurosci
, vol.23
, Issue.7
, pp. 1711-1720
-
-
Valerio, A.1
Boroni, F.2
Benarese, M.3
Sarnico, I.4
Ghisi, V.5
Bresciani, L.G.6
-
77
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
15152190 1:CAS:528:DC%2BD2cXkvVeku7Y%3D
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA et al (2004) Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23(12):2369-2380
-
(2004)
EMBO J
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
-
78
-
-
0037465541
-
Will caloric restriction and folate protect against AD and PD?
-
12601113 1:CAS:528:DC%2BD3sXptFKktw%3D%3D
-
Mattson MP (2003) Will caloric restriction and folate protect against AD and PD? Neurology 60(4):690-695
-
(2003)
Neurology
, vol.60
, Issue.4
, pp. 690-695
-
-
Mattson, M.P.1
-
79
-
-
27744495494
-
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase
-
16260491 1:CAS:528:DC%2BD2MXht1Sntr7E
-
Nathan C, Calingasan N, Nezezon J, Ding A, Lucia MS, La Perle K et al (2005) Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase. J Exp Med 202(9):1163-1169
-
(2005)
J Exp Med
, vol.202
, Issue.9
, pp. 1163-1169
-
-
Nathan, C.1
Calingasan, N.2
Nezezon, J.3
Ding, A.4
Lucia, M.S.5
La Perle, K.6
-
80
-
-
77955046461
-
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
-
20655472 1:CAS:528:DC%2BC3cXpsVahsrw%3D
-
Donmez G, Wang D, Cohen DE, Guarente L (2010) SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 142(2):320-332
-
(2010)
Cell
, vol.142
, Issue.2
, pp. 320-332
-
-
Donmez, G.1
Wang, D.2
Cohen, D.E.3
Guarente, L.4
-
81
-
-
35349011726
-
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
-
17964266 1:CAS:528:DC%2BD2sXhtlShtr7N
-
Kim EJ, Kho JH, Kang MR, Um SJ (2007) Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Mol Cell 28(2):277-290
-
(2007)
Mol Cell
, vol.28
, Issue.2
, pp. 277-290
-
-
Kim, E.J.1
Kho, J.H.2
Kang, M.R.3
Um, S.J.4
-
82
-
-
77957001697
-
Acetylation of tau inhibits its degradation and contributes to tauopathy
-
20869593 1:CAS:528:DC%2BC3cXht1Wisr3K
-
Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW et al (2010) Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron 67(6):953-966
-
(2010)
Neuron
, vol.67
, Issue.6
, pp. 953-966
-
-
Min, S.W.1
Cho, S.H.2
Zhou, Y.3
Schroeder, S.4
Haroutunian, V.5
Seeley, W.W.6
-
83
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
16751189 1:CAS:528:DC%2BD28XnsVOntLc%3D
-
Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L et al (2006) Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem 281(31):21745-21754
-
(2006)
J Biol Chem
, vol.281
, Issue.31
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
Zhao, Z.4
Wang, J.5
Chen, L.6
-
84
-
-
22844438667
-
Crosstalk between p53 and FOXO transcription factors
-
15611669 1:CAS:528:DC%2BD28XjtVert7c%3D
-
You H, Mak TW (2005) Crosstalk between p53 and FOXO transcription factors. Cell Cycle 4(1):37-38
-
(2005)
Cell Cycle
, vol.4
, Issue.1
, pp. 37-38
-
-
You, H.1
Mak, T.W.2
-
85
-
-
0042477712
-
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
-
12913110 1:CAS:528:DC%2BD3sXms1SqtrY%3D
-
Gilley J, Coffer PJ, Ham J (2003) FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 162(4):613-622
-
(2003)
J Cell Biol
, vol.162
, Issue.4
, pp. 613-622
-
-
Gilley, J.1
Coffer, P.J.2
Ham, J.3
-
86
-
-
80055082804
-
Parkinson's disease and alpha-synuclein expression
-
21887711
-
Devine MJ, Gwinn K, Singleton A, Hardy J (2011) Parkinson's disease and alpha-synuclein expression. Mov Disord 26(12):2160-2168
-
(2011)
Mov Disord
, vol.26
, Issue.12
, pp. 2160-2168
-
-
Devine, M.J.1
Gwinn, K.2
Singleton, A.3
Hardy, J.4
-
87
-
-
84862300236
-
Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease
-
22613205 1:CAS:528:DC%2BC38Xot12nurg%3D
-
Zhang A, Wang H, Qin X, Pang S, Yan B (2012) Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease. Biochem Biophys Res Commun 422(4):693-696
-
(2012)
Biochem Biophys Res Commun
, vol.422
, Issue.4
, pp. 693-696
-
-
Zhang, A.1
Wang, H.2
Qin, X.3
Pang, S.4
Yan, B.5
-
88
-
-
84855929223
-
SIRT1 protects against alpha-synuclein aggregation by activating molecular chaperones
-
22219275 1:CAS:528:DC%2BC38XovV2nuw%3D%3D
-
Donmez G, Arun A, Chung CY, McLean PJ, Lindquist S, Guarente L (2012) SIRT1 protects against alpha-synuclein aggregation by activating molecular chaperones. J Neurosci 32(1):124-132
-
(2012)
J Neurosci
, vol.32
, Issue.1
, pp. 124-132
-
-
Donmez, G.1
Arun, A.2
Chung, C.Y.3
McLean, P.J.4
Lindquist, S.5
Guarente, L.6
-
89
-
-
68949206606
-
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide
-
19558452 1:CAS:528:DC%2BD1MXhtVyntbzJ
-
Albani D, Polito L, Batelli S, De Mauro S, Fracasso C, Martelli G et al (2009) The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. J Neurochem 110(5):1445-1456
-
(2009)
J Neurochem
, vol.110
, Issue.5
, pp. 1445-1456
-
-
Albani, D.1
Polito, L.2
Batelli, S.3
De Mauro, S.4
Fracasso, C.5
Martelli, G.6
-
90
-
-
82455212997
-
Sirtuins in neurodegenerative diseases: A biological-chemical perspective
-
22041967 1:CAS:528:DC%2BC3MXhsFKjsLrO
-
Raghavan A, Shah ZA (2012) Sirtuins in neurodegenerative diseases: a biological-chemical perspective. Neurodegener Dis 9(1):1-10
-
(2012)
Neurodegener Dis
, vol.9
, Issue.1
, pp. 1-10
-
-
Raghavan, A.1
Shah, Z.A.2
-
91
-
-
69249084890
-
PGC-1{alpha} andPGC-1{beta} regulate mitochondrial density in neurons
-
19542216 1:CAS:528:DC%2BD1MXpt1Wisr0%3D
-
Wareski P, Vaarmann A, Choubey V, Safiulina D, Liiv J, Kuum M, Kaasik A (2009) PGC-1{alpha} andPGC-1{beta} regulate mitochondrial density in neurons. J Biol Chem 284:21379-21385
-
(2009)
J Biol Chem
, vol.284
, pp. 21379-21385
-
-
Wareski, P.1
Vaarmann, A.2
Choubey, V.3
Safiulina, D.4
Liiv, J.5
Kuum, M.6
Kaasik, A.7
-
92
-
-
51549098145
-
Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity
-
18675900 1:CAS:528:DC%2BD1cXhtFamsbbN
-
Chao J, Yu MS, Ho YS, Wang M, Chang RC (2008) Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity. Free Radic Biol Med 45:1019-1026
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1019-1026
-
-
Chao, J.1
Yu, M.S.2
Ho, Y.S.3
Wang, M.4
Chang, R.C.5
-
93
-
-
33845942205
-
Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults
-
17147953 1:CAS:528:DC%2BD2sXisVSnsQ%3D%3D
-
Okawara M, Katsuki H, Kurimoto E, Shibata H, Kume T, Akaike A (2007) Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults. Biochem Pharmacol 73:550-560
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 550-560
-
-
Okawara, M.1
Katsuki, H.2
Kurimoto, E.3
Shibata, H.4
Kume, T.5
Akaike, A.6
-
94
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
17051205 1:CAS:528:DC%2BD28XhtVyktbbO
-
Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443(7113):787-795
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
95
-
-
0021799202
-
The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
-
2581135 1:STN:280:DyaL2M7ovVWntA%3D%3D
-
Burns RS, LeWitt PA, Ebert MH, Pakkenberg H, Kopin IJ (1985) The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). N Engl J Med 312(22):1418-1421
-
(1985)
N Engl J Med
, vol.312
, Issue.22
, pp. 1418-1421
-
-
Burns, R.S.1
Lewitt, P.A.2
Ebert, M.H.3
Pakkenberg, H.4
Kopin, I.J.5
-
96
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
6823561 1:STN:280:DyaL3s7hvF2mtg%3D%3D
-
Langston JW, Ballard P, Tetrud JW, Irwin I (1983) Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219(4587):979-980
-
(1983)
Science
, vol.219
, Issue.4587
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
97
-
-
66249144714
-
Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells
-
19114014
-
Borland MK, Trimmer PA, Rubinstein JD, Keeney PM, Mohanakumar K, Liu L et al (2008) Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells. Mol Neurodegener 3:21
-
(2008)
Mol Neurodegener
, vol.3
, pp. 21
-
-
Borland, M.K.1
Trimmer, P.A.2
Rubinstein, J.D.3
Keeney, P.M.4
Mohanakumar, K.5
Liu, L.6
-
98
-
-
34249788747
-
Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome
-
17127363 1:CAS:528:DC%2BD28Xht1WgsLfP
-
Gomez C, Bandez MJ, Navarro A (2007) Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome. Front Biosci 12:1079-1093
-
(2007)
Front Biosci
, vol.12
, pp. 1079-1093
-
-
Gomez, C.1
Bandez, M.J.2
Navarro, A.3
-
99
-
-
38949185264
-
Modulation of sirtuins: New targets for antiageing
-
18221243 1:CAS:528:DC%2BD1cXitVCrs7c%3D
-
Pallas M, Verdaguer E, Tajes M, Gutierrez-Cuesta J, Camins A (2008) Modulation of sirtuins: new targets for antiageing. Recent Pat CNS Drug Discov 3(1):61-69
-
(2008)
Recent Pat CNS Drug Discov
, vol.3
, Issue.1
, pp. 61-69
-
-
Pallas, M.1
Verdaguer, E.2
Tajes, M.3
Gutierrez-Cuesta, J.4
Camins, A.5
-
100
-
-
25844487226
-
Diseases of unstable repeat expansion: Mechanisms and common principles
-
16205714 1:CAS:528:DC%2BD2MXhtVGru77J
-
Gatchel JR, Zoghbi HY (2005) Diseases of unstable repeat expansion: mechanisms and common principles. Nat Rev Genet 6(10):743-755
-
(2005)
Nat Rev Genet
, vol.6
, Issue.10
, pp. 743-755
-
-
Gatchel, J.R.1
Zoghbi, H.Y.2
-
101
-
-
79958265915
-
After the grape rush: Sirtuins as epigenetic drug targets in neurodegenerative disorders
-
21306906 1:CAS:528:DC%2BC3MXnsVyjtbo%3D
-
Huber K, Superti-Furga G (2011) After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders. Bioorg Med Chem 19(12):3616-3624
-
(2011)
Bioorg Med Chem
, vol.19
, Issue.12
, pp. 3616-3624
-
-
Huber, K.1
Superti-Furga, G.2
-
102
-
-
0027480960
-
-
Anonymous (1993) The Huntington's Disease Collaborative Research Group
-
Anonymous (1993) The Huntington's Disease Collaborative Research Group. Cell 72:971-983
-
Cell
, vol.72
, pp. 971-983
-
-
-
103
-
-
16844375290
-
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
-
15793589 1:CAS:528:DC%2BD2MXislCmu7w%3D
-
Parker JA, Arango M, Abderrahmane S, Lambert E, Tourette C, Catoire H et al (2005) Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat Genet 37(4):349-350
-
(2005)
Nat Genet
, vol.37
, Issue.4
, pp. 349-350
-
-
Parker, J.A.1
Arango, M.2
Abderrahmane, S.3
Lambert, E.4
Tourette, C.5
Catoire, H.6
-
104
-
-
33751282353
-
Huntington's disease: From huntingtin function and dysfunction to therapeutic strategies
-
17041811 1:CAS:528:DC%2BD28XhtlWqtrzN
-
Borrell-Pages M, Zala D, Humbert S, Saudou F (2006) Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies. Cell Mol Life Sci 63(22):2642-2660
-
(2006)
Cell Mol Life Sci
, vol.63
, Issue.22
, pp. 2642-2660
-
-
Borrell-Pages, M.1
Zala, D.2
Humbert, S.3
Saudou, F.4
-
105
-
-
33749042331
-
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
17018277 1:CAS:528:DC%2BD28XhtFSitr%2FP
-
Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D (2006) Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 127(1):59-69
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
106
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
15744310 1:CAS:528:DC%2BD2MXhslClsb0%3D
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434(7029):113-118
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
107
-
-
84855563516
-
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
-
1:CAS:528:DC%2BC3MXhs1eisb3M
-
Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR et al (2012) Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nat Med 18(1):159-165
-
(2012)
Nat Med
, vol.18
, Issue.1
, pp. 159-165
-
-
Jeong, H.1
Cohen, D.E.2
Cui, L.3
Supinski, A.4
Savas, J.N.5
Mazzulli, J.R.6
-
108
-
-
42949125477
-
SIRT1 and neuronal diseases
-
17397914 1:CAS:528:DC%2BD1cXlvVWiu74%3D
-
Tang BL, Chua CE (2008) SIRT1 and neuronal diseases. Mol Aspects Med 29(3):187-200
-
(2008)
Mol Aspects Med
, vol.29
, Issue.3
, pp. 187-200
-
-
Tang, B.L.1
Chua, C.E.2
-
109
-
-
0034633627
-
A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse
-
1:CAS:528:DC%2BD3cXnsF2ru7g%3D
-
Conforti L, Tarlton A, Mack TG, Mi W, Buckmaster EA, Wagner D et al (2000) A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse. Proc NatlAcadSci U S A 97(21):11377-11382
-
(2000)
Proc NatlAcadSci U S A
, vol.97
, Issue.21
, pp. 11377-11382
-
-
Conforti, L.1
Tarlton, A.2
Mack, T.G.3
Mi, W.4
Buckmaster, E.A.5
Wagner, D.6
-
110
-
-
0035195636
-
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene
-
11770485 1:CAS:528:DC%2BD3MXovVCqurc%3D
-
Mack TG, Reiner M, Beirowski B, Mi W, Emanuelli M, Wagner D et al (2001) Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat Neurosci 4(12):1199-1206
-
(2001)
Nat Neurosci
, vol.4
, Issue.12
, pp. 1199-1206
-
-
Mack, T.G.1
Reiner, M.2
Beirowski, B.3
Mi, W.4
Emanuelli, M.5
Wagner, D.6
-
111
-
-
77953290752
-
SIRT1-dependent regulation of chromatin and transcription: Linking NAD(+) metabolism and signaling to the control of cellular functions
-
19879981 1:CAS:528:DC%2BC3cXntlaltbg%3D
-
Zhang T, Kraus WL (2010) SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions. Biochim Biophys Acta 1804(8):1666-1675
-
(2010)
Biochim Biophys Acta
, vol.1804
, Issue.8
, pp. 1666-1675
-
-
Zhang, T.1
Kraus, W.L.2
-
112
-
-
79953274024
-
Pathways for ischemic cytoprotection: Role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning
-
21224864 1:CAS:528:DC%2BC3MXktFGjtrc%3D
-
Morris KC, Lin HW, Thompson JW, Perez-Pinzon MA (2011) Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning. J Cereb Blood Flow Metab 31(4):1003-1019
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, Issue.4
, pp. 1003-1019
-
-
Morris, K.C.1
Lin, H.W.2
Thompson, J.W.3
Perez-Pinzon, M.A.4
-
113
-
-
33747587373
-
Resveratrol mimics ischemic preconditioning in the brain
-
16395277 1:CAS:528:DC%2BD28XptlCitrY%3D
-
Raval AP, Dave KR, Perez-Pinzon MA (2006) Resveratrol mimics ischemic preconditioning in the brain. J Cereb Blood Flow Metab 26(9):1141-1147
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, Issue.9
, pp. 1141-1147
-
-
Raval, A.P.1
Dave, K.R.2
Perez-Pinzon, M.A.3
-
114
-
-
0027164824
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
8332197 1:CAS:528:DyaK3sXkvFaqtbg%3D
-
Rosen DR (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 364:362
-
(1993)
Nature
, vol.364
, pp. 362
-
-
Rosen, D.R.1
-
115
-
-
44049091481
-
Peroxisome proliferator-activated receptor-gamma in amyotrophic lateral sclerosis and Huntington's disease
-
18464922
-
Kiaei M (2008) Peroxisome proliferator-activated receptor-gamma in amyotrophic lateral sclerosis and Huntington's disease. PPAR Res 2008:418765
-
(2008)
PPAR Res
, vol.2008
, pp. 418765
-
-
Kiaei, M.1
|