Obese-derived ASCs show impaired migration and angiogenesis properties

Archives of Physiology and Biochemistry

Volumn 119, Issue 5, 2013, Pages 195-201

  Pérez, Laura M ^a   Bernal, Aurora ^a   San Martín, Nuria ^a   Gálvez, Beatriz G ^a  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

Adipose stem cells; Migration and angiogenesis; Obesity

Indexed keywords

ADIPOSE TISSUE; ADULT; ANGIOGENESIS; ANIMAL; ARTICLE; C57BL MOUSE; CELL MOTION; CELL SEPARATION; DRUG EFFECT; FEMALE; HUMAN; MIDDLE AGED; MOUSE; PATHOLOGY; STEM CELL;

ADIPOSE TISSUE; ADULT; ANIMALS; CELL MOVEMENT; CELL SEPARATION; FEMALE; HUMANS; MICE; MICE, INBRED C57BL; MIDDLE AGED; NEOVASCULARIZATION, PHYSIOLOGIC; STEM CELLS;

EID: 84887863573     PISSN: 13813455     EISSN: 17444160     Source Type: Journal    
DOI: 10.3109/13813455.2013.784339     Document Type: Article

References (30)

1. Ahima RS. (2009). Connecting obesity, aging and diabetes. Nat Med, 15: 996-7.
2. Baek SJ, Kang SK, Ra JC. (2011). In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors. Exp Mol Med, 43:596-603.
3. Bernal A, San Martin N, Fernandez M, et al. (2012). L-selectin and SDF-1 enhance the migration of mouse and human cardiac mesoangioblasts. Cell Death Differ, 19:345-55.
4. Chamberlain G, Fox J, Ashton B, Middleton, J. (2007). Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells, 25: 2739-49. (Pubitemid 350127858)
5. Cheng NC, Estes BT, Awad HA, Guilak F. (2009). Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix. Tissue Eng Part A, 15:231-41.
6. Chung HY, Cesari M, Anton S, et al. (2009). Molecular inflammation: Underpinnings of aging and age-related diseases. Ageing Res Rev, 8: 18-30.
7. Correia C, Grayson W, Eton R, et al. (2012). Human adipose-derived cells can serve as a single-cell source for the in vitro cultivation of vascularized bone grafts. J Tissue Eng Regen Med, [Epub ahead of print]. doi: 10.1002/term.1564.
8. Efimenko A, Starostina E, Kalinina N, Stolzing A. (2011). Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. J Transl Med, 9:10-15.
9. Galvez BG, Matias-Roman S, Albar JP, et al. (2001). Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodeling. J Biol Chem, 276:37491-500.
10. Galvez BG, Sampaolesi M, Brunelli S, et al. (2006). Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability. J Cell Biol, 174:231-43. (Pubitemid 44079858)
11. Galvez BG, San Martin N, Rodriguez C. (2009). TNF-alpha is required for the attraction of mesenchymal precursors to white adipose tissue in Ob/ob mice. PLoS One, 4:e4444. doi: 10.1371/journal. pone.0004444.
12. Herreros MD, Garcia-Arranz M, Guadalajara H, et al. (2012). Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: A phase III randomized clinical trial (FATT 1: Fistula Advanced Therapy Trial 1) and longterm evaluation. Dis Colon Rectum, 55:762-72.
13. Kern S, Eichler H, Stoeve J, et al. (2006). Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells, 24:1294-301. (Pubitemid 44464698)
14. Kim M, Kim I, Lee SK, et al. (2011). Clinical trial of autologous differentiated adipocytes from stem cells derived from human adipose tissue. Dermatol Surg, 37:750-9.
15. Konno M, Hamazaki TS, Fukuda S, et al. (2010). Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture. Biochem Biophys Res Commun, 400:461-5.
16. Krampera M, Marconi S, Pasini A, et al. (2007). Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus. Bone, 40:382-90. (Pubitemid 46054564)
17. Lee HC, An SG, Lee HW, et al. (2012). Safety and effect of adipose tissue-derived stem cell implantation in patients with critical limb ischemia. Circ J, 76:1750-60.
18. Lin G, Garcia M, Ning H, et al. (2008). Defining stem and progenitor cells within adipose tissue. Stem Cells Dev, 17:1053-63.
19. Madonna R, Renna FV, Cellini C, et al. (2011). Age-dependent impairment of number and angiogenic potential of adipose tissuederived progenitor cells. Eur J Clin Invest, 41:126-33.
20. Onate B, Vilahur G, Ferrer-Lorente R, et al. (2012). The subcutaneous adipose tissue reservoir of functionally active stem cells is reduced in obese patients. FASEB J, 26:4327-36.
21. Oswald J, Boxberger S, Jorgensen B, et al. (2004). Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells, 22:377-84. (Pubitemid 38736621)
22. Rehman J, Traktuev D, Li J, et al. (2004). Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells. Circulation, 109:1292-8. (Pubitemid 38372789)
23. Rodeheffer MS, Birsoy K, Friedman JM. (2008). Identification of white adipocyte progenitor cells in vivo. Cell, 135:240-9.
24. Rodriguez AM, Elabd C, Delteil F, et al. (2004). Adipocyte differentiation of multipotent cells established from human adipose tissue. Biochem Biophys Res Commun, 315:255-63. (Pubitemid 38183102)
25. Schmidt A, Ladage D, Steingen C, et al. (2006). Mesenchymal stem cells transmigrate over the endothelial barrier. Eur J Cell Biol, 85: 1179-88. (Pubitemid 44524624)
26. Shu W, Shu YT, Dai CY, Zhen QZ. (2012). Comparing the biological characteristics of adipose tissue-derived stem cells of different persons. J Cell Biochem, 113:2020-6.
27. Steingen C, Brenig F, Baumgartner L, et al. (2008). Characterization of key mechanisms in transmigration and invasion of mesenchymal stem cells. J Mol Cell Cardiol, 44:1072-84.
28. Teo GS, Ankrum JA, Martinelli R, et al. (2012). Mesenchymal stem cells transmigrate between and directly through TNF-alpha-activated endothelial cells. Stem Cells, 30:2472-86.
29. Zhu M, Kohan E, Bradley J, et al. (2009). The effect of age on osteogenic, adipogenic and proliferative potential of female adiposederived stem cells. J Tissue Eng Regen Med, 3:290-301.
30. Zuk PA, Zhu M, Ashjian P, et al. (2002). Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell, 13: 4279-95. (Pubitemid 35471185)