Viscoelastic properties of the P17 and adult rat brain from indentation in the coronal plane

Journal of Biomechanical Engineering

Volumn 135, Issue 11, 2013, Pages

  Elkin, Benjamin S ^a,b   Morrison, Barclay ^a  

^a Department of Earth and Environmental Sciences   (United States)

^b MEA Forensic Engineers and Scientists   (Canada)

Author keywords

age dependence; heterogeneous mechanical properties; indentation; neurosurgery; rat brain; TBI; viscoelasticity

Indexed keywords

AGE DEPENDENCE; LEAST SQUARES FITTING; MICRO-INDENTATION TESTS; RAT BRAIN; TBI; TRAUMATIC BRAIN INJURIES; VISCOELASTIC CHARACTERIZATION; VISCOELASTIC PROPERTIES;

BRAIN; INDENTATION; NEUROSURGERY; RATS; SAMPLING; TIME MEASUREMENT; VISCOELASTICITY;

STIFFNESS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN REGION; CEREBELLUM; DEVICES; FINITE ELEMENT ANALYSIS; GENERAL DEVICE; GROUND REACTION FORCE; HIPPOCAMPUS; NONHUMAN; RAT; RATING SCALE; SHEAR STRESS; TRAUMATIC BRAIN INJURY; VISCOELASTICITY; WHITE MATTER; ANIMAL; ELASTICITY; EQUIPMENT; MATERIALS TESTING; METHODOLOGY; MICROTECHNOLOGY; TIME; VISCOSITY; PROCEDURES;

ANIMALS; BRAIN; ELASTICITY; MATERIALS TESTING; MICROTECHNOLOGY; RATS; TIME FACTORS; VISCOSITY;

EID: 84887829799     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4025386     Document Type: Article

References (29)

1. Xiong, Y., Mahmood, A., and Chopp, M., 2013, "Animal Models of Traumatic Brain Injury, " Nat. Rev. Neurosci., 14, pp. 128-142.
2. Li, Y., Zhang, L., Kallakuri, S., Zhou, R., and Cavanaugh, J. M., 2011, "Quantitative Relationship Between Axonal Injury and Mechanical Response in a Rodent Head Impact Acceleration Model, " J. Neurotrauma, 28, pp. 1767-1782.
3. Takhounts, E. G., Ridella, S. A., Hasija, V., Tannous, R. E., Campbell, J. Q., Malone, D., and Duma, S., 2008, "Investigation of Traumatic Brain Injuries Using the Next Generation of Simulated Injury Monitor (SIMon) Finite Element Head Model, " Stapp Car Crash J., 52, pp. 1-31. Available at: http://www.simbex.com/BRP/links/Takhouts-EG-2008-InvestigationOfTraumatic- BrainInjuriesUsingNextGenSIMon-StappCCJ.pdf
4. Mao, H., Guan, F., Han, X., and Yang, K. H., 2011, "Strain-Based Regional Traumatic Brain Injury Intensity in Controlled Cortical Impact: A Systematic Numerical Analysis, " J. Neurotrauma, 28, pp. 2263-2276.
5. Elkin, B. S., Azeloglu, E. U., Costa, K. D., and Morrison, B. III, 2007, "Mechanical Heterogeneity of the Rat Hippocampus Measured by Atomic Force Microscope Indentation, " J. Neurotrauma, 24, pp. 812-822. (Pubitemid 46799273)
6. Elkin, B. S., Ilankovan, A., and Morrison, B. III, 2010, "Age-Dependent Regional Mechanical Properties of the Rat Hippocampus and Cortex, " ASME J. Biomech. Eng., 132(1), p. 011010.
7. Gefen, A., Gefen, N., Zhu, Q., Raghupathi, R., and Margulies, S. S., 2003, "Age-Dependent Changes in Material Properties of the Brain and Braincase of the Rat, " J. Neurotrauma, 20, pp. 1163-1177. (Pubitemid 37467280)
8. Elias, P. Z., and Spector, M., 2012, "Viscoelastic Characterization of Rat Cerebral Cortex and Type I Collagen Scaffolds for Central Nervous System Tissue Engineering, " J. Mech. Behav. Biomed. Mater., 12, pp. 63-73.
9. Vappou, J., Breton, E., Choquet, P., Willinger, R., Goetz, C., and Constanti-nesco, A., 2007, "Magnetic Resonance Elastography Compared With Rotational Rheometry for in Vitro Brain Tissue Viscoelasticity Measurement, " MAGMA (N.Y.), 20, pp. 273-278.
10. Vappou, J., Breton, E., Choquet, P., Willinger, R., and Constantinesco, A., 2008, "Assessment of in Vivo and Post-Mortem Mechanical Behavior of Brain Tissue Using Magnetic Resonance Elastography, " J. Biomech., 41, pp. 2954-2959.
11. Christ, A. F., Franze, K., Gautier, H., Moshayedi, P., Fawcett, J., Franklin, R. J. M., Karadottir, R. T., and Guck, J., 2010, "Mechanical Difference Between White and Gray Matter in the Rat Cerebellum Measured by Scanning Force Microscopy, " J. Biomech., 43, pp. 2986-2992.
12. Lee, S. J., Sun, J., Flint, J. J., Guo, S., Xie, H. K., King, M. A., and Sarntinora-nont, M., 2011, "Optically Based-Indentation Technique for Acute Rat Brain Tissue Slices and Thin Biomaterials, " J. Biomed. Mater. Res., Part B: Appl. Biomater., 97, pp. 84-95.
13. Shulyakov, A. V., Cenkowski, S. S., Buist, R. J., and Del Bigio, M. R., 2011, "Age-Dependence of Intracranial Viscoelastic Properties in Living Rats, " J. Mech. Behav. Biomed. Mater., 4, pp. 484-497.
14. Clayton, E. H., Garbow, J. R., and Bayly, P. V., 2011, "Frequency-Dependent Viscoelastic Parameters of Mouse Brain Tissue Estimated by MR Elastography, " Phys. Med. Biol., 56, pp. 2391-2406.
15. Cheng, L., Xia, X., Yu, W., Scriven, L. E., and Gerberich, W.W., 2000, "Flat-Punch Indentation of Viscoelastic Material, " J. Polym. Sci., Part B: Polym. Phys., 38, pp. 10-22. (Pubitemid 30519015)
16. Zamir, E. A., and Taber, L.A., 2004, "On the Effects of Residual Stress in Microindentation Tests of Soft Tissue Structures, " ASME J. Biomech. Eng., 126(2), pp. 276-283. (Pubitemid 38621141)
17. Elkin, B. S., Ilankovan, A. I., and Morrison, B. III, 2011, "A Detailed Visco-elastic Characterization of the P17 and Adult Rat Brain, " J. Neurotrauma, 28, pp. 2235-2244.
18. Finan, J. D., Elkin, B. S., Pearson, E. M., Kalbian, I. L., and Morrison, B. III, 2012, "Viscoelastic Properties of the Rat Brain in the Sagittal Plane: Effects of Anatomical Structure and Age, " Ann. Biomed. Eng., 40, pp. 70-78.
19. Finan, J. D., Pearson, E. M., and Morrison, B. III, 2012, "Viscoelastic Properties of the Rat Brain in the Horizontal Plane, " Proceedings of the IRCOBI Conference, Paper No. IRC-12-57.
20. Elkin, B. S., Ilankovan, A., and Morrison, B. III, 2011, "Dynamic, Regional Mechanical Properties of the Porcine Brain: Indentation in the Coronal Plane, " ASME J. Biomech. Eng., 133(7), p. 071009.
21. Hayes, W. C., Herrmann, G., Mockros, L. F., and Keer, L. M. 1972, "A Mathematical Analysis for Indentation Tests of Articular Cartilage, " J. Biomech, 5, pp. 541-551.
22. Radok, J. R. M., and Lee, E. H., 1960, "The Contact Problem for Viscoelastic Bodies, " ASME J. Appl. Mech., 27(3), pp. 438-444.
23. Allen, M. P., 1997, "Testing Hypotheses in Nested Regression Models, " Understanding Regression Analysis, Plenum, New York, pp. 113-115.
24. Massey, F. J., 1951, "The Kolmogorov-Smirnov Test for Goodness of Fit, " J. Am. Stat. Assoc., 46, pp. 68-78.
25. Bonferroni, C. E., 1935, "Il Calcolo Delle Assicurazioni su Gruppi di Teste, " Tipografia del Senato, Studi in Onore del Professore Salvatore Ortu Carboni, Bardi, Rome, Italy, pp. 13-60.
26. Sakai, M., 2002, "Time-Dependent Viscoelastic Relation Between Load and Penetration for an Axisymmetric Indenter, " Philos. Mag. A, 82, pp. 1841-1849. (Pubitemid 35393304)
27. Arbogast, K. B., and Margulies, S. S., 1999, "A Fiber-Reinforced Composite Model of the Viscoelastic Behavior of the Brainstem in Shear, " J. Biomech., 32, pp. 865-870. (Pubitemid 29287110)
28. Cater, H. L., Sundstrom, L. E., and Morrison, B. III, 2006, "Temporal Development of Hippocampal Cell Death is Dependent on Tissue Strain but not Strain Rate, " J. Biomech., 39, pp. 2810-2818. (Pubitemid 44637144)
29. Elkin, B. S., and Morrison, B. III, 2007, "Region-Specific Tolerance Criteria for the Living Brain, " Stapp Car Crash J., 51, pp. 127-138. Available at: http://papers.sae.org/2007-22-0005/