Umbilical cord mesenchymal stem cell transplantation ameliorates burn-induced acute kidney injury in rats

International Journal of Lower Extremity Wounds

Volumn 12, Issue 3, 2013, Pages 205-211

  Lu, Gang ^a   Huang, Sha ^a,b   Chen, Yongbin ^a   Ma, Kui ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

acute kidney injury (AKI); burn; mesenchymal stromal cells (MSCs); transplantation; umbilical cord (UC)

Indexed keywords

PROTEIN BCL 2; ULINASTATIN;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BURN; KIDNEY CELL; KIDNEY FUNCTION; KIDNEY STRUCTURE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; SURVIVAL; THERAPY EFFECT; THERMAL INJURY; UMBILICAL CORD; UPREGULATION;

ACUTE KIDNEY INJURY (AKI); BURN; MESENCHYMAL STROMAL CELLS (MSCS); TRANSPLANTATION; UMBILICAL CORD (UC);

ACUTE KIDNEY INJURY; ANIMALS; BURNS; DISEASE MODELS, ANIMAL; FOLLOW-UP STUDIES; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME; UMBILICAL CORD;

EID: 84887581875     PISSN: 15347346     EISSN: 15526941     Source Type: Journal    
DOI: 10.1177/1534734613502041     Document Type: Article

References (17)

1. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999 ; 284: 143-147
2. Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem. 2006 ; 98: 1076-1084
3. Morigi M, Introna M, Imberti B, et al. Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells. 2008 ; 26: 2075-2082
4. Furuichi K, Shintani H, Sakai Y, et al. Effects of adipose-derived mesenchymal cells on ischemia-reperfusion injury in kidney. Clin Exp Nephrol. 2012 ; 16: 679-689
5. Westenfelder C, Togel FE. Protective actions of administered mesenchymal stem cells in acute kidney injury: relevance to clinical trials. Kidney Int Supplements. 2011 ; 1: 103-106
6. Patel J, Pancholi N, Gudehithlu KP, et al. Stem cells from foreign body granulation tissue accelerate recovery from acute kidney injury. Nephrol Dial Transplant. 2012 ; 27: 1780-1786
7. Ricci Z, Cruz D, Ronco C. The RIFLE criteria and mortality in acute kidney injury: a systematic review. Kidney Int. 2008 ; 73: 538-546
8. Hoste EA, Clermont G, Kersten A, et al. RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care. 2006 ; 10: R73 - R82
9. Palmieri T, Lavrentieva A, Greenhalgh DG. Acute kidney injury in critically ill burn patients. Risk factors, progression and impact on mortality. Burns. 2010 ; 36: 205-211
10. Qiao C, Xu W, Zhu W, et al. Human mesenchymal stem cells isolated from the umbilical cord. Cell Biol Int. 2008 ; 32: 8-15
11. Baksh D, Yao R, Tuan RS. Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow. Stem Cells. 2007 ; 25: 1384-1392
12. Coca SG, Bauling P, Schifftner T, Howard CS, Teitelbaum I, Parikh CR. Contribution of acute kidney injury toward morbidity and mortality in burns: a contemporary analysis. Am J Kidney Dis. 2007 ; 49: 517-523
13. Parker RA, Himmelfarb J, Tolkoff-Rubin N, Chandran P, Wingard RL, Hakim RM. Prognosis of patients with acute renal failure requiring dialysis: results of a multicenter study. Am J Kidney Dis. 1998 ; 32: 432-443
14. Doorn J, Moll G, Le Blanc K, van Blitterswijk C, de Boer J. Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements. Tissue Eng Part B Rev. 2012 ; 18: 101-115
15. Friedman R, Betancur M, Boissel L, Tuncer H, Cetrulo C, Klingemann H. Umbilical cord mesenchymal stem cells: adjuvants for human cell transplantation. Biol Blood Marrow Transplant. 2007 ; 13: 1477-1486
16. Bruno S, Grange C, Collino F, et al. Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. PLoS One. 2012 ; 7: e33115
17. Chipuk JE, Moldoveanu T, Llambi F, Parsons MJ, Green DR. The BCL-2 family reunion. Mol Cell. 2010 ; 37: 299-310