Irreversible electroporation: Ready for prime time?

Techniques in Vascular and Interventional Radiology

Volumn 16, Issue 4, 2013, Pages 277-286

  Lu, David S K ^a   Kee, Stephen T ^a   Lee, Edward W ^a  

^a UCLA MEDICAL CENTER   (United States)

Author keywords

Image guided; Interventional oncology; Irreversible electroporation; Solid tumor; Tumor ablation

Indexed keywords

AMYLASE; CASPASE 3; TRIACYLGLYCEROL LIPASE;

ADVANCED CANCER; AMYLASE BLOOD LEVEL; APOPTOSIS; ARTERIAL LINE; AXONAL INJURY; BILE DUCT; BLOOD PRESSURE MONITORING; BLOOD VESSEL INJURY; BRONCHIOLE; BRONCHUS; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER MORTALITY; CANCER RECURRENCE; CANCER REGRESSION; CANCER SURGERY; CANCER SURVIVAL; CARDIAC SYNCHRONIZATION; CELL DEATH; CHEMOEMBOLIZATION; CHOLESTASIS; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONVALESCENCE; ELECTROCARDIOGRAM; ELECTRODE; ELECTROLYTE DISTURBANCE; ENDONEURIUM; ENZYME ACTIVATION; FOLLOW UP; GASTROINTESTINAL TRACT; GENERAL ANESTHESIA; HEAD AND NECK TUMOR; HEART ARRHYTHMIA; HEART CYCLE; HEART MUSCLE CONDUCTION DISTURBANCE; HEART RHYTHM; HEMODYNAMICS; HIGH INTENSITY FOCUSED ULTRASOUND; HISTOPATHOLOGY; HUMAN; HYPERPLASIA; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTESTINE PERFORATION; IRREVERSIBLE ELECTROPORATION; KIDNEY CARCINOMA; KIDNEY TUMOR; LAPAROTOMY; LIVER BLOOD VESSEL; LIVER CELL CARCINOMA; LIVER METASTASIS; LIVER TUMOR; LIVER VEIN; LUNG TUMOR; METASTASIS; MICROWAVE THERAPY; MINIMALLY INVASIVE SURGERY; MUSCLE CONTRACTION; MUSCLE TWITCH; MYELIN SHEATH; NECROSIS; NERVE FIBER REGENERATION; NERVE PARALYSIS; NEUROMUSCULAR BLOCKING; NONHUMAN; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PANCREAS CARCINOMA; PANCREAS DUCT; PANCREATITIS; PORTAL VEIN; PORTAL VEIN THROMBOSIS; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PROGRESSION FREE SURVIVAL; PROTEIN DENATURATION; RECURRENCE RISK; REFRACTORY PERIOD; REVIEW; ROBOTICS; SAFETY; SCHWANN CELL; SCIATIC NERVE; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; STEM CELL; SUPRAVENTRICULAR TACHYCARDIA; SURVIVAL TIME; THERAPY EFFECT; THERMAL INJURY; THROMBOSIS; TISSUE INJURY; TISSUE STRUCTURE; TRACHEA; TREATMENT DURATION; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; TUMOR ABLATION; TUMOR VOLUME; VASCULAR THROMBOSIS; XENOGRAFT;

IMAGE GUIDED; INTERVENTIONAL ONCOLOGY; IRREVERSIBLE ELECTROPORATION; SOLID TUMOR; TUMOR ABLATION;

ABLATION TECHNIQUES; ANIMALS; ELECTROPORATION; HUMANS; NEOPLASMS; SURGERY, COMPUTER-ASSISTED; TREATMENT OUTCOME;

EID: 84887579067     PISSN: 10892516     EISSN: 15579808     Source Type: Journal    
DOI: 10.1053/j.tvir.2013.08.010     Document Type: Review

References (48)

1. Ahmed M, Brace CL, Lee FT Jr, et al: Principles of and advances in percutaneous ablation. Radiology 258:351-369.
2. Cirocchi R, Trastulli S, Boselli C, et al: Radiofrequency ablation in the treatment of liver metastases from colorectal cancer. Cochrane Database Syst Rev 6:CD006317, 2012.
3. Gamblin TC, Christians K, Pappas SG: Radiofrequency ablation of neuroendocrine hepatic metastasis. Surg Oncol Clin N Am 20:273-279, vii-viii, 2011.
4. Lencioni R, Crocetti L: Image-guided ablation for hepatocellular carcinoma. Recent Results Cancer Res 190:181-194, 2013.
5. Sharma A, Abtin F, Shepard JA: Image-guided ablative therapies for lung cancer. Radiol Clin North Am 50:975-999, 2012.
6. Venkatesan AM, Wood BJ, Gervais DA Percutaneous ablation in the kidney. Radiology 261:375-391, 2011.
7. Lu D.S., Raman S.S., Limanond P., et al. Influence of large peritumoral vessels on outcome of radiofrequency ablation of liver tumors. J Vasc Interv Radiol 2003, 14:1267-1274.
8. Raman S.S., Aziz D., Chang X., et al. Minimizing central bile duct injury during radiofrequency ablation: use of intraductal chilled saline perfusion-Initial observations from a study in pigs. Radiology 2004, 232:154-159.
9. Yu N.C., Raman S.S., Kim Y.J., et al. Microwave liver ablation: Influence of hepatic vein size on heat-sink effect in a porcine model. J Vasc Interv Radiol 2008, 19:1087-1092.
10. Rubinsky B. Irreversible electroporation in medicine. Technol Cancer Res Treat 2007, 6:255-260.
11. Gehl J. Electroporation: Theory and methods, perspectives for drug delivery, gene therapy and research. Acta Physiol Scand 2003, 177:437-447.
12. Chang D.C., Reese T.S. Changes in membrane structure induced by electroporation as revealed by rapid-freezing electron microscopy. Biophys J 1990, 58:1-12.
13. Lee E.W., Wong D., Prikhodko S.V., et al. Electron microscopic demonstration and evaluation of irreversible electroporation-induced nanopores on hepatocyte membranes. J Vasc Interv Radiol 2012, 23:107-113.
14. Lee E.W., Wong D., Tafti B.A., et al. Irreversible Electroporation in Eradication of Rabbit VX2 Liver Tumor. J Vasc Interv Radiol 2012, 23:833-840.
15. Lee E.W., Chen C., Prieto V.E., et al. Advanced hepatic ablation technique for creating complete cell death: Irreversible electroporation. Radiology 2010, 255:426-433.
16. Lee E.W., Loh C.T., Kee S.T. Imaging guided percutaneous irreversible electroporation: ultrasound and immunohistological correlation. Technol Cancer Res Treat 2007, 6:287-294.
17. Livraghi T., Meloni F., Solbiati L., et al. Complications of microwave ablation for liver tumors: Results of a multicenter study. Cardiovasc Intervent Radiol 2012, 35:868-874.
18. Deodhar A., Dickfeld T., Single G.W., et al. Irreversible electroporation near the heart: ventricular arrhythmias can be prevented with ECG synchronization. Am J Roentgenol 2011, 196:W330-W335.
19. Charpentier KP, Wolf F, Noble L, et al: Irreversible electroporation of the liver and liver hilum in swine. HPB (Oxford) 13:168-173, 2011.
20. Lee YJ, Lu DS, Osuagwu F, et al: Irreversible electroporation in porcine liver: short- and long-term effect on the hepatic veins and adjacent tissue by CT with pathological correlation. Invest Radiol 47:671-675, 2012.
21. Choi J, Lu DS, Osuagwu F, et al: Chronological effects of IRE on hilar bile ducts in a porcine model. Paper presented at: Society of Interventional Radiology Annual Meeting; 03/2011, 2011, San Francisco.
22. Charpentier KP, Wolf F, Noble L, et al: Irreversible electroporation of the pancreas in swine: a pilot study. HPB (Oxford) 12:348-351, 2010.
23. Choi J, Lu DS, Osuagwu F, et al: Irreversible electroporation of pancreatic tissue: Short and long term safety evaluation in a porcine model. Paper presented at: Radiological Society of North America scientific assembly and annual meeting program; 11/2011, 2011, Chicago.
24. Deodhar A, Monette S, Single GW, Jr, et al: Percutaneous irreversible electroporation lung ablation: Preliminary results in a porcine model. Cardiovasc Intervent Radiol 34:1278-1287, 2011.
25. Dupuy DE, Aswad B, Ng T Irreversible electroporation in a Swine lung model. Cardiovasc Intervent Radiol 34:391-395, 2011.
26. Deodhar A, Monette S, Single GW, Jr, et al: Renal tissue ablation with irreversible electroporation: preliminary results in a porcine model. Urology 77:754-760, 2011.
27. Phillips MA, Narayan R, Padath T, et al: Irreversible electroporation on the small intestine. Br J Cancer; 106:490-495, 2012.
28. Schoellnast H, Monette S, Ezell PC, et al: Irreversible electroporation adjacent to the rectum: evaluation of pathological effects in a pig model. Cardiovasc Intervent Radiol 36:213-220, 2013.
29. Li W, Fan Q, Ji Z, et al: The effects of irreversible electroporation (IRE) on nerves. PLoS One 6:e18831, 2011.
30. Schoellnast H, Monette S, Ezell PC, et al: Acute and subacute effects of irreversible electroporation on nerves: experimental study in a pig model. Radiology 260:421-427, 2011.
31. Schoellnast H, Monette S, Ezell PC, et al: The delayed effects of irreversible electroporation ablation on nerves. Eur Radiol 23:375-380, 2013.
32. Faroja M, Ahmed M, Appelbaum L, et al: Irreversible electroporation ablation: is all the damage nonthermal? Radiology 266:462-470, 2013.
33. Lee YJ, Lu DS, Osuagwu F, et al: Irreversible electroporation in porcine liver: acute computed tomography appearance of ablation zone with histopathologic correlation. J Comput Assist Tomogr 37:154-158, 2013.
34. Olweny EO, Kapur P, Tan YK, et al: Irreversible electroporation: Evaluation of nonthermal and thermal ablative capabilities in the porcine kidney. Urology 81:679-684, 2013.
35. Al-Sakere B., Andre F., Bernat C., et al. Tumor ablation with irreversible electroporation. PLoS One 2007, 2:e1135.
36. Wong D, Lee EW, Prieto V, et al: Evaluating the effects of IRE on VX2 rabbit head and neck tumor model: A preliminary results. Paper presented at: Society of Interventional Radiology Annual Meeting 03/2013, 2011, Chicago.
37. Jose A, Sobrevals L, Ivorra A, et al: Irreversible electroporation shows efficacy against pancreatic carcinoma without systemic toxicity in mouse models. Cancer Lett 317:16-23, 2012.
38. Thomson K.R., Cheung W., Ellis S.J., et al. Investigation of the safety of irreversible electroporation in humans. J Vasc Interv Radiol 2011, 22:611-621.
39. Pech M, Janitzky A, Wendler JJ, et al: Irreversible electroporation of renal cell carcinoma: a first-in-man phase I clinical study. Cardiovasc Intervent Radiol 34:132-138, 2011.
40. Cheung W, Kavnoudias H, Roberts S, et al: Irreversible electroporation for unresectable hepatocellular carcinoma: Initial experience and review of safety and outcomes. Technol Cancer Res Treat 12:233-241, 2013.
41. Kingham TP, Karkar AM, D'Angelica MI, et al: Ablation of perivascular hepatic malignant tumors with irreversible electroporation. J Am Coll Surg 215:379-387, 2012.
42. Cannon R, Ellis S, Hayes D, et al:. Safety and early efficacy of irreversible electroporation for hepatic tumors in proximity to vital structures. J Surg Oncol 107:544-549, 2013.
43. Narayanan G, Hosein PJ, Arora G, et al: Percutaneous irreversible electroporation for downstaging and control of unresectable pancreatic adenocarcinoma. J Vasc Interv Radiol 23:1613-1621, 2012.
44. Martin RC, 2nd, McFarland K, Ellis S, et al: Irreversible electroporation in locally advanced pancreatic cancer: Potential improved overall survival. Ann Surg Oncol 44:e-pub, nov 2012.
45. Ball C., Thomson K.R., Kavnoudias H. Irreversible electroporation: a new challenge in "out of operating theater" anesthesia. Anesth Analg 2010, 110:1305-1309.
46. Ben-David E, Appelbaum L, Sosna J, et al: Characterization of irreversible electroporation ablation in in vivo porcine liver. Am J Roentgenol 198:W62-W68, 2012.
47. Raman S.S., Lu D.S., Vodopich D.J., et al. Creation of radiofrequency lesions in a porcine model: correlation with sonography, CT, and histopathology. Am J Roentgenol 2000, 175:1253-1258.
48. Appelbaum L, Ben-David E, Sosna J, et al: US findings after irreversible electroporation ablation: radiologic-pathologic correlation. Radiology 262:117-125, 2012.