-
1
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
10.1016/j.cell.2010.06.011, 2914105, 20602996
-
Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2010, 141:1117-1134. 10.1016/j.cell.2010.06.011, 2914105, 20602996.
-
(2010)
Cell
, vol.141
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
2
-
-
84864367360
-
The ERBB network: at last, cancer therapy meets systems biology
-
Yarden Y, Pines G. The ERBB network: at last, cancer therapy meets systems biology. Nat Rev Cancer 2012, 12:553-563.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 553-563
-
-
Yarden, Y.1
Pines, G.2
-
3
-
-
78649663247
-
Triple-negative breast cancer: disease entity or title of convenience?
-
10.1038/nrclinonc.2010.154, 20877296
-
Carey L, Winer E, Viale G, Cameron D, Gianni L. Triple-negative breast cancer: disease entity or title of convenience?. Nat Rev Clin Oncol 2010, 7:683-692. 10.1038/nrclinonc.2010.154, 20877296.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 683-692
-
-
Carey, L.1
Winer, E.2
Viale, G.3
Cameron, D.4
Gianni, L.5
-
4
-
-
84867118148
-
Emerging targeted therapies in triple-negative breast cancer
-
10.1093/annonc/mds196, 23012305
-
Crown J, O'Shaughnessy J, Gullo G. Emerging targeted therapies in triple-negative breast cancer. Ann Oncol 2012, 23(Suppl 6):vi56-vi65. 10.1093/annonc/mds196, 23012305.
-
(2012)
Ann Oncol
, vol.23
, Issue.SUPPL. 6
-
-
Crown, J.1
O'Shaughnessy, J.2
Gullo, G.3
-
5
-
-
84884167635
-
The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells
-
10.1126/scisignal.2004155, 23921085
-
Meyer AS, Miller MA, Gertler FB, Lauffenburger DA. The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal 2013, 6:ra66. 10.1126/scisignal.2004155, 23921085.
-
(2013)
Sci Signal
, vol.6
-
-
Meyer, A.S.1
Miller, M.A.2
Gertler, F.B.3
Lauffenburger, D.A.4
-
6
-
-
79953060389
-
Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer
-
10.1038/onc.2010.509, 21057535
-
Vuoriluoto K, Haugen H, Kiviluoto S, Mpindi JP, Nevo J, Gjerdrum C, Tiron C, Lorens JB, Ivaska J. Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer. Oncogene 2011, 30:1436-1448. 10.1038/onc.2010.509, 21057535.
-
(2011)
Oncogene
, vol.30
, pp. 1436-1448
-
-
Vuoriluoto, K.1
Haugen, H.2
Kiviluoto, S.3
Mpindi, J.P.4
Nevo, J.5
Gjerdrum, C.6
Tiron, C.7
Lorens, J.B.8
Ivaska, J.9
-
7
-
-
84864402225
-
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
-
10.1038/ng.2330, 3408577, 22751098
-
Zhang Z, Lee JC, Lin L, Olivas V, Au V, LaFramboise T, Abdel-Rahman M, Wang X, Levine AD, Rho JK, Choi YJ, Choi CM, Kim SW, Jang SJ, Park YS, Kim WS, Lee DH, Lee JS, Miller VA, Arcila M, Ladanyi M, Moonsamy P, Sawyers C, Boggon TJ, Ma PC, Costa C, Taron M, Rosell R, Halmos B, Bivona TG. Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer. Nat Genet 2012, 44:852-860. 10.1038/ng.2330, 3408577, 22751098.
-
(2012)
Nat Genet
, vol.44
, pp. 852-860
-
-
Zhang, Z.1
Lee, J.C.2
Lin, L.3
Olivas, V.4
Au, V.5
LaFramboise, T.6
Abdel-Rahman, M.7
Wang, X.8
Levine, A.D.9
Rho, J.K.10
Choi, Y.J.11
Choi, C.M.12
Kim, S.W.13
Jang, S.J.14
Park, Y.S.15
Kim, W.S.16
Lee, D.H.17
Lee, J.S.18
Miller, V.A.19
Arcila, M.20
Ladanyi, M.21
Moonsamy, P.22
Sawyers, C.23
Boggon, T.J.24
Ma, P.C.25
Costa, C.26
Taron, M.27
Rosell, R.28
Halmos, B.29
Bivona, T.G.30
more..
-
8
-
-
84871998076
-
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
-
10.1158/1078-0432.CCR-12-1558, 23091115
-
Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res 2013, 19:279-290. 10.1158/1078-0432.CCR-12-1558, 23091115.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 279-290
-
-
Byers, L.A.1
Diao, L.2
Wang, J.3
Saintigny, P.4
Girard, L.5
Peyton, M.6
Shen, L.7
Fan, Y.8
Giri, U.9
Tumula, P.K.10
Nilsson, M.B.11
Gudikote, J.12
Tran, H.13
Cardnell, R.J.14
Bearss, D.J.15
Warner, S.L.16
Foulks, J.M.17
Kanner, S.B.18
Gandhi, V.19
Krett, N.20
Rosen, S.T.21
Kim, E.S.22
Herbst, R.S.23
Blumenschein, G.R.24
Lee, J.J.25
Lippman, S.M.26
Ang, K.K.27
Mills, G.B.28
Hong, W.K.29
Weinstein, J.N.30
Wistuba, I.I.31
Coombes, K.R.32
Minna, J.D.33
Heymach, J.V.34
more..
-
9
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
Sharma SV, Bell DW, Settleman J, Haber DA. Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 2007, 7:169-181.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 169-181
-
-
Sharma, S.V.1
Bell, D.W.2
Settleman, J.3
Haber, D.A.4
-
10
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
-
10.1126/scitranslmed.3002003, 3132801, 21430269
-
Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, Lynch TJ, Vernovsky K, Mark EJ, Lanuti M, Iafrate AJ, Mino-Kenudson M, Engelman JA. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011, 3:75ra26. 10.1126/scitranslmed.3002003, 3132801, 21430269.
-
(2011)
Sci Transl Med
, vol.3
-
-
Sequist, L.V.1
Waltman, B.A.2
Dias-Santagata, D.3
Digumarthy, S.4
Turke, A.B.5
Fidias, P.6
Bergethon, K.7
Shaw, A.T.8
Gettinger, S.9
Cosper, A.K.10
Akhavanfard, S.11
Heist, R.S.12
Temel, J.13
Christensen, J.G.14
Wain, J.C.15
Lynch, T.J.16
Vernovsky, K.17
Mark, E.J.18
Lanuti, M.19
Iafrate, A.J.20
Mino-Kenudson, M.21
Engelman, J.A.22
more..
-
11
-
-
84878243037
-
Signalling change: signal transduction through the decades
-
10.1038/nrm3581, 23636498
-
Hynes NE, Ingham PW, Lim WA, Marshall CJ, Massague J, Pawson T. Signalling change: signal transduction through the decades. Nat Rev Mol Cell Biol 2013, 14:393-398. 10.1038/nrm3581, 23636498.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 393-398
-
-
Hynes, N.E.1
Ingham, P.W.2
Lim, W.A.3
Marshall, C.J.4
Massague, J.5
Pawson, T.6
-
12
-
-
84860389233
-
Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy
-
10.1186/bcr2857, 3219198, 21457545
-
Teng YH, Tan WJ, Thike AA, Cheok PY, Tse GM, Wong NS, Yip GW, Bay BH, Tan PH. Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy. Breast Cancer Res 2011, 13:R35. 10.1186/bcr2857, 3219198, 21457545.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Teng, Y.H.1
Tan, W.J.2
Thike, A.A.3
Cheok, P.Y.4
Tse, G.M.5
Wong, N.S.6
Yip, G.W.7
Bay, B.H.8
Tan, P.H.9
-
13
-
-
33746911642
-
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
-
10.1002/path.2004, 16739104
-
Reis-Filho JS, Pinheiro C, Lambros MB, Milanezi F, Carvalho S, Savage K, Simpson PT, Jones C, Swift S, Mackay A, Reis RM, Hornick JL, Pereira EM, Baltazar F, Fletcher CD, Ashworth A, Lakhani SR, Schmitt FC. EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J Pathol 2006, 209:445-453. 10.1002/path.2004, 16739104.
-
(2006)
J Pathol
, vol.209
, pp. 445-453
-
-
Reis-Filho, J.S.1
Pinheiro, C.2
Lambros, M.B.3
Milanezi, F.4
Carvalho, S.5
Savage, K.6
Simpson, P.T.7
Jones, C.8
Swift, S.9
Mackay, A.10
Reis, R.M.11
Hornick, J.L.12
Pereira, E.M.13
Baltazar, F.14
Fletcher, C.D.15
Ashworth, A.16
Lakhani, S.R.17
Schmitt, F.C.18
-
14
-
-
22244473343
-
The fallacy of epithelial mesenchymal transition in neoplasia
-
discussion 6000-6001, 10.1158/0008-5472.CAN-05-0699, 16024596
-
Tarin D, Thompson EW, Newgreen DF. The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 2005, 65:5996-6000. discussion 6000-6001, 10.1158/0008-5472.CAN-05-0699, 16024596.
-
(2005)
Cancer Res
, vol.65
, pp. 5996-6000
-
-
Tarin, D.1
Thompson, E.W.2
Newgreen, D.F.3
-
15
-
-
84867984708
-
Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer
-
10.1007/s10555-012-9377-5, 22729277
-
Gunasinghe NP, Wells A, Thompson EW, Hugo HJ. Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer. Cancer Metastasis Rev 2012, 31:469-478. 10.1007/s10555-012-9377-5, 22729277.
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 469-478
-
-
Gunasinghe, N.P.1
Wells, A.2
Thompson, E.W.3
Hugo, H.J.4
|