Evaluation of a web-based intervention to reduce antibiotic prescribing for LRTI in six European countries: Quantitative process analysis of the GRACE/INTRO randomised controlled trial

Implementation Science

Volumn 8, Issue 1, 2013, Pages

  Yardley, Lucy ^a   Douglas, Elaine ^b   Anthierens, Sibyl ^c   Tonkin Crine, Sarah ^d   O'Reilly, Gilly ^d   Stuart, Beth ^d   Geraghty, Adam W A ^d   Arden Close, Emily ^a   van der Velden, Alike W ^e   Goosens, Herman ^c   Verheij, Theo J M ^e   Butler, Chris C ^f   Francis, Nick A ^f   Little, Paul ^d  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Antibiotics; Prescribing; Questionnaires; Resistance

Indexed keywords

ANTIINFECTIVE AGENT;

ACUTE DISEASE; ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; CLUSTER ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EDUCATION; EUROPE; FEMALE; GENERAL PRACTITIONER; HUMAN; INAPPROPRIATE PRESCRIBING; INTERNET; MALE; MIDDLE AGED; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION;

ACUTE DISEASE; ADULT; ANTI-BACTERIAL AGENTS; CLUSTER ANALYSIS; DRUG RESISTANCE, MICROBIAL; EUROPE; FEMALE; GENERAL PRACTITIONERS; HUMANS; INAPPROPRIATE PRESCRIBING; INTERNET; MALE; MIDDLE AGED; QUESTIONNAIRES; RESPIRATORY TRACT INFECTIONS;

EID: 84887548485     PISSN: None     EISSN: 17485908     Source Type: Journal    
DOI: 10.1186/1748-5908-8-134     Document Type: Article

References (42)

1. Costelloe C, Metcalfe C, Lovering A, Mant D, Hay AD. Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis. BMJ 2010, 340:c2096. 10.1136/bmj.c2096, 20483949.
2. Goossens H, Ferech M, Vander Stichele R, Elseviers M. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005, 365:579-587. 10.1016/S0140-6736(05)17907-0, 15708101.
3. Butler CC, Dunstan F, Heginbothom M, Mason B, Roberts Z, Hillier S, Howe R, Palmer S, Howard A. Containing antibiotic resistance: decreased antibiotic-resistant coliform urinary tract infections with reduction in antibiotic prescribing by general practices. Br J Gen Pract 2007, 57:785-792. 2151810, 17925135.
4. Smith SM, Fahey T, Smucny J, Becker LA. Antibiotics for acute bronchitis. Cochrane Database Syst Rev 2004, 4:CD000245.
5. Butler CC, Hood K, Verheij T, Little P, Melbye H, Nuttall J, Kelly MJ, Mölstad S, Godycki-Cwirko M, Almirall J, et al. Variation in antibiotic prescribing and its impact on recovery in patients with acute cough in primary care: prospective study in 13 countries. BMJ 2009, 338:B2242. 10.1136/bmj.b2242, 3272656, 19549995.
6. Little P, Stuart B, Francis N, Douglas E, Tonkin-Crine S, Anthierens S, Cals JWL, Melbye H, Santer M, Moore M, Coenen S, Butler C, Hood K, Kelly M, Godycki-Cwirko M, Mierzecki A, Torres A, Llor C, Davies M, Mullee M, O'Reilly G, van der Velden A, Geraghty AWA, Goosens H, Verheij T, Yardley L, on behalf of the GRACE consortium The effect of web-based training in communication skills and an interactive patient booklet and the use of a CRP point of care test in acute respiratory tract infection (RTI): a multi-national cluster randomised factorial controlled trial. Lancet 2013, 1175-1182. on behalf of the GRACE consortium.
7. Tonkin-Crine S, Yardley L, Little P. Antibiotic prescribing for acute respiratory tract infections in primary care: a systematic review and meta-ethnography. J Antimicrob Chemother 2011, 66:2215-2223. 10.1093/jac/dkr279, 21764827.
8. Walker AE, Grimshaw J, Armstrong E. Salient beliefs and intentions to prescribe antibiotics for patients with a sore throat. Br J Health Psychol 2001, 6:347-360. 10.1348/135910701169250, 12614509.
9. Björnsdóttir I, Hansen EH. Intentions, strategies and uncertainty inherent in antibiotic prescribing. Eur J Gen Pract 2002, 8:18-24.
10. Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: qualitative study of general practitioners' and patients' perceptions of antibiotics for sore throat. Br Med J 1998, 317:637-642.
11. Simpson SA, Wood F, Butler CC. General practitioners' perceptions of antimicrobial resistance: a qualitative study. J Antimicrob Chemother 2007, 59:292-296.
12. Akkerman AE, Kuyvenhoven MM, van der Wouden JC, Verheij TJ. Prescribing antibiotics for respiratory tract infections by GPs: management and prescriber characteristics. Br J Gen Pract 2005, 55:114-118. 1463185, 15720932.
13. Kumar S, Little P, Britten N. Why do general practitioners prescribe antibiotics for sore throat? Grounded interview study. Br Med J 2003, 326:138.
14. Tonkin-Crine S, Yardley L, Coenen S, Fernandez-Vandellos P, Krawczyk J, Touboul P, Verheij T, Little P. GPs' views in five European countries of interventions to promote prudent antibiotic use. Br J Gen Pract 2011, 61:e252-e261. 10.3399/bjgp11X572445, 3080230, 21619749.
15. Brookes-Howell L, Hood K, Cooper L, Coenen S, Little P, Verheij T, Godycki-Cwirko M, Melbye H, Krawczyk J, Borras-Santos A, et al. Clinical influences on antibiotic prescribing decisions for lower respiratory tract infection: a nine country qualitative study of variation in care. BMJ Open 2012, 2:e000795. 3364454, 22619265.
16. Arnold SR, Straus SE. Interventions to improve antibiotic prescribing practices in ambulatory care. Cochrane Database Syst Rev 2005, CD003539.
17. Butler CC, Simpson SA, Dunstan F, Rollnick S, Cohen D, Gillespie D, Evans MR, Alam MF, et al. Effectiveness of multifaceted educational programme to reduce antibiotic dispensing in primary care: practice based randomised controlled trial. BMJ 2012, 344:d8173. 10.1136/bmj.d8173, 3270575, 22302780.
18. Francis NA, Butler CC, Hood K, Simpson S, Wood F, Nuttall J. Effect of using an interactive booklet about childhood respiratory tract infections in primary care consultations on reconsulting and antibiotic prescribing: a cluster randomised controlled trial. BMJ 2009, 339:b2885. 10.1136/bmj.b2885, 2718088, 19640941.
19. Cals JW, Butler CC, Hopstaken RM, Hood K, Dinant GJ. Effect of point of care testing for C reactive protein and training in communication skills on antibiotic use in lower respiratory tract infections: cluster randomised trial. BMJ 2009, 338:b1374. 10.1136/bmj.b1374, 2677640, 19416992.
20. Ajzen I. The theory of planned behavior. Organ Behav Hum Decis Process 1991, 50:179-211.
21. Eccles MP, Grimshaw JM, Johnston M, Steen N, Pitts NB, Thomas R, Glidewell E, Maclennan G, Bonetti D, Walker A. Applying psychological theories to evidence-based clinical practice: identifying factors predictive of managing upper respiratory tract infections without antibiotics. Implement Sci 2007, 2:26. 10.1186/1748-5908-2-26, 2042498, 17683558.
22. Hrisos S, Eccles M, Johnston M, Francis J, Kaner EFS, Steen N, Grimshaw J. An intervention modelling experiment to change GP's intentions to implement evidence-based practice: using theory-based interventions to promote GP management of upper respiratory tract infection without prescribing anti-biotics. BMC Health Serv Res 2008, 8:10. 10.1186/1472-6963-8-10, 2262061, 18194526.
23. Godin G, Kok G. The theory of planned behavior: a review of its applications to health-related behaviors. Am J Health Promot 1996, 11:87-98. 10.4278/0890-1171-11.2.87, 10163601.
24. Armitage CJ, Conner M. Efficacy of the theory of planned behaviour: A meta-analytic review. Br J Soc Psychol 2001, 40:471-499. 10.1348/014466601164939, 11795063.
25. Bjerrum L, Munck A, Gahrn-Hansen B, Hansen MP, Jarbol DE, Cordoba G, Llor C, Cots JM, Hernandez S, Lopez-Valcarcel BG, et al. Health Alliance for prudent antibiotic prescribing in patients with respiratory tract infections (HAPPY AUDIT) -impact of a non-randomised multifaceted intervention programme. BMC Fam Pract 2011, 12:52. 10.1186/1471-2296-12-52, 3146837, 21689406.
26. Huttner B, Goossens H, Verheij T, Harbarth S. Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries. Lancet Infect Dis 2010, 10:17-31. 10.1016/S1473-3099(09)70305-6, 20129146.
27. Yardley L, Osmond A, Hare J, Wills G, Weal M, de Roure D, Michie S. Introduction to the LifeGuide: software facilitating the development of interactive behaviour change internet interventions Edinburgh: Proceedings of the AISB Convention.
28. Yardley L, Joseph J, Michie S, Weal M, Wills G, Little P. Evaluation of a Web-based intervention providing tailored advice for self-management of minor respiratory symptoms: exploratory randomized controlled trial. J Med Internet Res 2010, 12:e66. 10.2196/jmir.1599, 3056528, 21159599.
29. Horne R. Treatment perceptions and self-regulation. The self-regulation of health and illness behaviour 2003, 138-153. London: Routledge, Leventhal H, Cameron LD.
30. Leventhal HA, Brissette I, Leventhal EA. The common-sense model of self-regulation of health and illness. The self-regulation of health and illness behaviour 2003, 42-65. London: Routledge, Cameron LD, Leventhal H.
31. Anthierens S, Tonkin-Crine S, Douglas E, Fernandez-Vandellos P, Krawczyk J, Llor C, Cals JW, Francis NA, Yardley L, Coenen S, et al. General practitioners' views on the acceptability and applicability of a web-based intervention to reduce antibiotic prescribing for acute cough in multiple European countries: a qualitative study prior to a randomised trial. BMC Fam Pract 2012, 13:101. 10.1186/1471-2296-13-101, 3533906, 23110756.
32. Howie JG, Heaney DJ, Maxwell M, Walker JJ. A comparison of a Patient Enablement Instrument (PEI) against two established satisfaction scales as an outcome measure of primary care consultations. Fam Pract 1998, 15:165-171. 10.1093/fampra/15.2.165, 9613486.
33. Cals JW, Butler CC, Dinant GJ. 'Experience talks': physician prioritisation of contrasting interventions to optimise management of acute cough in general practice. Implement Sci 2009, 4:57. 10.1186/1748-5908-4-57, 2742510, 19737382.
34. Butler CC, Simpson S, Wood F. General practitioners' perceptions of introducing near-patient testing for common infections into routine primary care: a qualitative study. Scand J Prim Health Care 2008, 26:17-21. 10.1080/02813430701726285, 3406622, 18297558.
35. Wood F, Brookes-Howell L, Hood K, Cooper L, Verheij T, Goossens H, Little P, Godycki-Cwirko M, Adriaenssens N, Jakobsen K, Butler CC. A multi-country qualitative study of clinicians' and patients' views on point of care tests for lower respiratory tract infection. Fam Pract 2011, 28:661-669. 10.1093/fampra/cmr031, 21653924.
36. Cals JW, Chappin FH, Hopstaken RM, van Leeuwen ME, Hood K, Butler CC, Dinant GJ. C-reactive protein point-of-care testing for lower respiratory tract infections: a qualitative evaluation of experiences by GPs. Fam Pract 2010, 27:212-218. 10.1093/fampra/cmp088, 20022909.
37. Francis N, Wood F, Simpson S, Hood K, Butler CC. Developing an 'interactive' booklet on respiratory tract infections in children for use in primary care consultations. Patient Educ Couns 2008, 73:286-293. 10.1016/j.pec.2008.07.020, 18723306.
38. Bekkers MJ, Simpson SA, Dunstan F, Hood K, Hare M, Evans J, Butler CC. Enhancing the quality of antibiotic prescribing in primary care: qualitative evaluation of a blended learning intervention. BMC Fam Pract 2010, 11:34. 10.1186/1471-2296-11-34, 2881907, 20459655.
39. McDermott L, Yardley L, Little P, Ashworth M, Gulliford M. Developing a computer delivered, theory based intervention for guideline implementation in general practice. BMC Fam Pract 2010, 11:90. 10.1186/1471-2296-11-90, 2995485, 21087469.
40. Brookes-Howell L, Hood K, Cooper L, Little P, Verheij T, Coenen S, Godycki-Cwirko M, Melbye H, Borras-Santos A, Worby P, et al. Understanding variation in primary medical care: a nine-country qualitative study of clinicians' accounts of the non-clinical factors that shape antibiotic prescribing decisions for lower respiratory tract infection. BMJ Open 2012, 2:e000796.
41. Little P, Somerville J, Williamson I, Warner G, Moore M, Wiles R, George S, Smith A, Peveler R. Randomised controlled trial of self management leaflets and booklets for minor illness provided by post. BMJ 2001, 322:1214-1217. 10.1136/bmj.322.7296.1214, 31621, 11358775.
42. Cals JWL, De Bock L, Beckers P-JHW, Francis NA, Hopstaken RM, Hood K, De Bont EGPM, Butler CC, Dinant G-J. Enhanced communication skills and C-reactive protein point-of-care testing for respiratory tract Infection: 3.5-year follow-up of a cluster randomized trial. Ann Fam Med 2013, 11:157-164. 10.1370/afm.1477, 3601394, 23508603.