Genome-wide binding of the basic helix-loop-helix myogenic inhibitor musculin has substantial overlap with MyoD: Implications for buffering activity

Skeletal Muscle

Volumn 3, Issue 1, 2013, Pages

  MacQuarrie, Kyle L ^a,b   Yao, Zizhen ^a   Fong, Abraham P ^a,c   Tapscott, Stephen J ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

musculin; MyoD; myogenic inhibitor; Rhabdomyosarcoma

Indexed keywords

EID: 84887530162     PISSN: None     EISSN: 20445040     Source Type: Journal    
DOI: 10.1186/2044-5040-3-26     Document Type: Article

References (27)

1. MacQuarrie KL, Fong AP, Morse RH, Tapscott SJ. Genome-wide transcription factor binding: beyond direct target regulation. Trends Genet 2011, 27:141-148. 10.1016/j.tig.2011.01.001, 3068217, 21295369.
2. Davis RL, Weintraub H, Lassar AB. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 1987, 51:987-1000. 10.1016/0092-8674(87)90585-X, 3690668.
3. Cao Y, Yao Z, Sarkar D, Lawrence M, Sanchez GJ, Parker MH, MacQuarrie KL, Davison J, Morgan MT, Ruzzo WL, Gentleman RC, Tapscott SJ. Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming. Dev Cell 2010, 18:662-674. 10.1016/j.devcel.2010.02.014, 2910615, 20412780.
4. Berkes CA, Tapscott SJ. MyoD and the transcriptional control of myogenesis. Semin Cell Dev Biol 2005, 16:585-595. 10.1016/j.semcdb.2005.07.006, 16099183.
5. Benezra R, Davis RL, Lockshon D, Turner DL, Weintraub H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 1990, 61:49-59. 10.1016/0092-8674(90)90214-Y, 2156629.
6. Spicer DB, Rhee J, Cheung WL, Lassar AB. Inhibition of myogenic bHLH and MEF2 transcription factors by the bHLH protein Twist. Science 1996, 272:1476-1480. 10.1126/science.272.5267.1476, 8633239.
7. St-Pierre B, Flock G, Zacksenhaus E, Egan SE. Stra13 homodimers repress transcription through class B E-box elements. J biol chem 2002, 277:46544-46551. 10.1074/jbc.M111652200, 12297495.
8. Lemercier C, To RQ, Carrasco RA, Konieczny SF. The basic helix-loop-helix transcription factor Mist1 functions as a transcriptional repressor of myoD. EMBO J 1998, 17:1412-1422. 10.1093/emboj/17.5.1412, 1170489, 9482738.
9. Hamamori Y, Wu HY, Sartorelli V, Kedes L. The basic domain of myogenic basic helix-loop-helix (bHLH) proteins is the novel target for direct inhibition by another bHLH protein, Twist. Mol Cell Biol 1997, 17:6563-6573. 232510, 9343420.
10. Lu J, Webb R, Richardson JA, Olson EN. MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. Proc Natl Acad Sci USA 1999, 96:552-557. 10.1073/pnas.96.2.552, 15174, 9892671.
11. Lu J-R, Bassel-Duby R, Hawkins A, Chang P, Valdez R, Wu H, Gan L, Shelton JM, Richardson JA, Olson EN. Control of facial muscle development by MyoR and capsulin. Science 2002, 298:2378-2381. 10.1126/science.1078273, 12493912.
12. Moncaut N, Cross JW, Siligan C, Keith A, Taylor K, Rigby PW, Carvajal JJ. Musculin and TCF21 coordinate the maintenance of myogenic regulatory factor expression levels during mouse craniofacial development. Development 2012, 139:958-967. 10.1242/dev.068015, 3274357, 22318627.
13. Lee GH, Chang MY, Hsu CH, Chen YH. Essential roles of basic helix-loop-helix transcription factors, capsulin and musculin, during craniofacial myogenesis of zebrafish. Cell Mol Life Sci 2011, 68:4065-4078. 10.1007/s00018-011-0637-2, 21347725.
14. Ismat A, Schaub C, Reim I, Kirchner K, Schultheis D, Frasch M. HLH54F is required for the specification and migration of longitudinal gut muscle founders from the caudal mesoderm of Drosophila. Development 2010, 137:3107-3117. 10.1242/dev.046573, 2926959, 20736287.
15. Hishikawa K, Marumo T, Miura S, Nakanishi A, Matsuzaki Y, Shibata K, Ichiyanagi T, Kohike H, Komori T, Takahashi I, Takase O, Imai N, Yoshikawa M, Inowa T, Hayashi M, Nakaki T, Nakauchi H, Okano H, Fujita T. Musculin/MyoR is expressed in kidney side population cells and can regulate their function. J Cell Biol 2005, 169:921-928. 10.1083/jcb.200412167, 2171631, 15967813.
16. Yu L, Sangster N, Perez A, McCormick PJ. The bHLH protein MyoR inhibits the differentiation of early embryonic endoderm. Differentiation 2004, 72:341-347. 10.1111/j.1432-0436.2004.07207005.x, 15554945.
17. Yu L, Mikloucich J, Sangster N, Perez A, McCormick PJ. MyoR is expressed in nonmyogenic cells and can inhibit their differentiation. Exp Cell Res 2003, 289:162-173. 10.1016/S0014-4827(03)00252-0, 12941614.
18. Yang Z, MacQuarrie KL, Analau E, Tyler AE, Dilworth FJ, Cao Y, Diede SJ, Tapscott SJ. MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state. Genes Dev 2009, 23:694-707. 10.1101/gad.1765109, 2661613, 19299559.
19. MacQuarrie KL, Yao Z, Young JM, Cao Y, Tapscott SJ. miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells. Skeletal Muscle 2012, 2:7. 10.1186/2044-5040-2-7, 3417070, 22541669.
20. Saab R, Spunt SL, Skapek SX. Chapter 7 - myogenesis and rhabdomyosarcoma: the Jekyll and Hyde of skeletal muscle. Current Top Dev Biol Cancer Dev 2010, 94:197-234.
21. MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJ. Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of pro-myogenic transcription factors. Mol Cell Biol 2013, 33:773-784. 10.1128/MCB.00916-12, 3571334, 23230269.
22. Tapscott SJ, Davis RL, Thayer MJ, Cheng PF, Weintraub H, Lassar AB. MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts. Science 1988, 242:405-411. 10.1126/science.3175662, 3175662.
23. Davis RL, Cheng PF, Lassar AB, Weintraub H. The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation. Cell 1990, 60:733-746. 10.1016/0092-8674(90)90088-V, 2155707.
24. Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell 2012, 22:721-735. 10.1016/j.devcel.2012.01.015, 3331915, 22445365.
25. Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth FJ, Gentleman R, Tapscott SJ, Brand M. Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages. EMBO J 2011, 30:494-509. 10.1038/emboj.2010.342, 3034015, 21179004.
26. Genetta T, Ruezinsky D, Kadesch T. Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer. Mol Cell Biol 1994, 14:6153-6163. 10.1128/MCB.14.9.6153, 359142, 8065348.
27. Soleimani VD, Yin H, Jahani-Asl A, Ming H, Kockx CE, van Ijcken WF, Grosveld F, Rudnicki MA. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Mol Cell 2012, 47:457-468. 10.1016/j.molcel.2012.05.046, 22771117.