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1
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84872749270
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Molecular remission after bortezomib-thalidomide-dexamethasone compared with thalidomide-dexamethasone as consolidation therapy following double autologous transplantation for multiple myeloma: Results of a qualitative and quantitative analysis
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Abstract P224
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Terragna C, Zamagni E, Petrucci MT=, et al. Molecular remission after bortezomib-thalidomide-dexamethasone compared with thalidomide-dexamethasone as consolidation therapy following double autologous transplantation for multiple myeloma: results of a qualitative and quantitative analysis. Haematologica 2011;96(s1):S96. Abstract P224.
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Terragna, C.1
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2
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84860741191
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Lenalidomide after stem-cell transplantation for multiple myeloma
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McCarthy PL, Owzar K, Hofmeister CC, et al. Lenalidomide after stem-cell transplantation for multiple myeloma. N Engl J Med 2012;366:1770-1781.
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McCarthy, P.L.1
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Hofmeister, C.C.3
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3
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84884703339
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Pomalidomide with low-dose dexamethasone in patients with relapsed and refractory multiple myeloma who have received prior therapy with lenalidomide and bortezomib: Updated phase 2 results and age subgroup analysis [abstract]
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Jagannath S, Hofmeister CC, Siegel DS, et al. Pomalidomide with low-dose dexamethasone in patients with relapsed and refractory multiple myeloma who have received prior therapy with lenalidomide and bortezomib: updated phase 2 results and age subgroup analysis [abstract]. Blood 2012;120: Abstract 450.
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Blood
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Jagannath, S.1
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84884702342
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Pomalidomide plus low-dose dexamethasone in relapsed myeloma: Long term follow-up and factors predicting outcome in 345 patients [abstract]
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Lacy MQ, Kumar S, LaPlant B, et al. Pomalidomide plus low-dose dexamethasone in relapsed myeloma: long term follow-up and factors predicting outcome in 345 patients [abstract]. Blood 2012;120: Abstract 201.
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Blood
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Lacy, M.Q.1
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5
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84874908368
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Pomalidomide in combination with low-dose dexamethasone demonstrates a significant progression-free survival and overall survival advantage in relapsed/refractory multiple myeloma: A phase 3, multicenter, randomized, open-label study [abstract]
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Dimopoulos MA, Lacy MQ, Moreau P, et al. Pomalidomide in combination with low-dose dexamethasone demonstrates a significant progression-free survival and overall survival advantage in relapsed/refractory multiple myeloma: a phase 3, multicenter, randomized, open-label study [abstract]. Blood 2012;120: Abstract 6.
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Blood
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Dimopoulos, M.A.1
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84884701276
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MM-005: A phase 1, multicenter, open-label, dose-escalation study to determine the maximum tolerated dose for the combination of pomalidomide, bortezomib, and low-dose dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma [abstract]
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Richardson PG, Hofmeister CC, Siegel D, et al. MM-005: A phase 1, multicenter, open-label, dose-escalation study to determine the maximum tolerated dose for the combination of pomalidomide, bortezomib, and low-dose dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma [abstract]. Blood 2012;120: Abstract 727.
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Richardson, P.G.1
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7
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A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
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Siegel DS, Martin T, Wang M, et al. A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma. Blood 2012;120:2817-2825.
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Siegel, D.S.1
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8
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84862688138
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Interim results from PX-171-006, a phase II multicenter dose-expansion study of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed and/or refractory multiple myeloma [abstract]
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Wang W, Bensinger W, Martin T, et al. Interim results from PX-171-006, a phase II multicenter dose-expansion study of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed and/or refractory multiple myeloma [abstract]. J Clin Oncol 2011;29(Suppl 15): Abstract 8025.
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A phase 1b/2 study of prolonged infusion carfilzomib in patients with relapsed and/or refractory multiple myeloma: Updated efficacy and tolerability from the completed 20/56 mg/m2 expansion cohort of PX-171-007 [abstract]
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Papadopoulos KP, Lee P, Singhal S, et al. A phase 1b/2 study of prolonged infusion carfilzomib in patients with relapsed and/or refractory multiple myeloma: updated efficacy and tolerability from the completed 20/56 mg/m2 expansion cohort of PX-171-007 [abstract]. Blood 2011;118: Abstract 2930.
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Papadopoulos, K.P.1
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A phase 2 study of elotuzumab in combination with lenalidomide and low-dose dexamethasone in patients with relapsed/refractory multiple myeloma: Updated rresults [abstract]
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Richardson PG, Jagannath S, Moreau P, et al. A phase 2 study of elotuzumab in combination with lenalidomide and low-dose dexamethasone in patients with relapsed/refractory multiple myeloma: updated rresults [abstract]. Blood 2012;120: Abstract 202.
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Richardson, P.G.1
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11
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84878159958
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Daratumumab, a CD38 monoclonal antibody in patients with multiple myeloma: Data from a dose-escalation phase I/II study [abstract]
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Plesner T, Lokhorst H, Gimsing P, et al. Daratumumab, a CD38 monoclonal antibody in patients with multiple myeloma: data from a dose-escalation phase I/II study [abstract]. Blood 2012;120: Abstract 73.
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Plesner, T.1
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A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance
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Chauhan D, Tian Z, Nicholson B, et al. A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell 2012;22:345-358.
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84862644984
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Investigational agent MLN9708, an oral proteasome inhibitor, in patients with relapsed and/or refractory multiple myeloma: Results from the expansion cohorts of phase 1 dose-escalation study [abstract]
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Richardson PG, Baz R, Wang L, et al. Investigational agent MLN9708, an oral proteasome inhibitor, in patients with relapsed and/or refractory multiple myeloma: results from the expansion cohorts of phase 1 dose-escalation study [abstract]. Blood 2011;118: Abstract 301.
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Richardson, P.G.1
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BET bromodomain inhibition as a therapeutic strategy to target c-Myc
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15
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84887495310
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Vantage 088: Vorinostat in combination with bortezomib in patients with relapsed/refractory multiple myeloma: Results of a global, randomized phase 3 trial
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Presented, Abstract 811
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Dimopoulos ME, Jagannath S, Yoon S-S, et al. Vantage 088: vorinostat in combination with bortezomib in patients with relapsed/refractory multiple myeloma: results of a global, randomized phase 3 trial. Presented at the 2011 American Society of Hematology Annual Meeting. Abstract 811.
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The 2011 American Society of Hematology Annual Meeting
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Dimopoulos, M.E.1
Jagannath, S.2
Yoon, S.-S.3
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16
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84858640254
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Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
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Santo L, Hideshima T, Kung AL, et al. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma. Blood 2012;119:2579-2589.
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