A multi-centre, blinded, randomised, placebo-controlled, laboratory-based study of MQX-503, a novel topical gel formulation of nitroglycerine, in patients with Raynaud phenomenon

Annals of the Rheumatic Diseases

Volumn 72, Issue 12, 2013, Pages 1962-1967

  Hummers, Laura K ^a   Dugowson, Carin E ^b   Dechow, Frederick J ^c   Wise, Robert A ^a   Gregory, Jeffrey ^d   Michalek, Joel ^e   Yenokyan, Gayane ^f   McGready, John ^f   Wigley, Fredrick M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c MediQuest Therapeutics Inc   (United States)

^d Acucela Inc   (United States)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^f JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE; MQX 503; PLACEBO; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG FORMULATION; DRUG SCREENING; DRUG TOLERABILITY; FEMALE; GEL; HEADACHE; HUMAN; HYPERTENSION; LABORATORY TEST; LASER DOPPLER FLOWMETRY; MALE; MULTICENTER STUDY; PARESTHESIA; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RAYNAUD PHENOMENON; SKIN BLOOD FLOW; SKIN PAIN; SKIN TEMPERATURE; SKIN TINGLING; TREATMENT OUTCOME;

SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; TREATMENT;

ADMINISTRATION, CUTANEOUS; ADULT; AGED; CHEMISTRY, PHARMACEUTICAL; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; GELS; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NITROGLYCERIN; RAYNAUD DISEASE; REGIONAL BLOOD FLOW; SKIN; SKIN TEMPERATURE; TREATMENT OUTCOME; VASODILATOR AGENTS; YOUNG ADULT;

EID: 84887451338     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2012-201536     Document Type: Article

References (19)

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