PD-1, but not PD-L1, expressed by islet-Reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes

Diabetes

Volumn 62, Issue 8, 2013, Pages 2859-2869

  Pauken, Kristen E ^a   Jenkins, Marc K ^a   Azuma, Miyuki ^b   Fife, Brian T ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; LYMPHOCYTE ANTIGEN; PROGRAMMED DEATH 1; PROGRAMMED DEATH 1 LIGAND 1; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; CD274 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CELL TRANSFER; CONTROLLED STUDY; CYTOKINE PRODUCTION; HISTOPATHOLOGY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; LYMPH NODE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PANCREAS; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; T LYMPHOCYTE ACTIVATION; ANIMAL; CELL DIFFERENTIATION; CELL PROLIFERATION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PATHOLOGY; PHYSIOLOGY;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD274; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 1; ISLETS OF LANGERHANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NOD; PANCREAS; PROGRAMMED CELL DEATH 1 RECEPTOR;

EID: 84887445713     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1475     Document Type: Article

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