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Volumn 18, Issue 11, 2013, Pages 1214-1220

Chemotherapy with erlotinib or chemotherapy alone in advanced non-small cell lung cancer with acquired resistance to EGFR tyrosine kinase inhibitors

Author keywords

Drug resistance; Epidermal growth factor receptor; Non small cell lung cancer; Protein kinase inhibitor

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; PACLITAXEL;

EID: 84887434792     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2013-0168     Document Type: Article
Times cited : (111)

References (34)
  • 1
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Maemondo M, Inoue A, Kobayashi K et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;362: 2380-2388.
    • (2010) N Engl J Med , vol.362 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 2
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with nonsmall- cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
    • Mitsudomi T, Morita S, Yatabe Y et al. Gefitinib versus cisplatin plus docetaxel in patients with nonsmall- cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial. Lancet Oncol 2010;11:121-128.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3
  • 3
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 4
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
    • Rosell R, Carcereny E, Gervais R et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13:239-246.
    • (2012) Lancet Oncol , vol.13 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3
  • 5
    • 80052437758 scopus 로고    scopus 로고
    • New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer
    • Oxnard GR, Arcila ME, Chmielecki J et al. New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer. Clin Cancer Res 2011;17: 5530-5537.
    • (2011) Clin Cancer Res , vol.17 , pp. 5530-5537
    • Oxnard, G.R.1    Arcila, M.E.2    Chmielecki, J.3
  • 6
    • 79960085862 scopus 로고    scopus 로고
    • Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling
    • Chmielecki J, Foo J, Oxnard GR et al. Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling. Sci Transl Med 2011;3:90ra59.
    • (2011) Sci Transl Med , vol.3
    • Chmielecki, J.1    Foo, J.2    Oxnard, G.R.3
  • 7
    • 80053531654 scopus 로고    scopus 로고
    • Disease flare after tyrosine kinase inhibitor discontinuation in patients with EGFR-mutant lung cancer and acquired resistance to erlotinib or gefitinib: Implications for clinical trial design
    • Chaft JE, Oxnard GR, Sima CS et al. Disease flare after tyrosine kinase inhibitor discontinuation in patients with EGFR-mutant lung cancer and acquired resistance to erlotinib or gefitinib: Implications for clinical trial design. Clin Cancer Res 2011;17:6298-6303.
    • (2011) Clin Cancer Res , vol.17 , pp. 6298-6303
    • Chaft, J.E.1    Oxnard, G.R.2    Sima, C.S.3
  • 8
    • 34548853993 scopus 로고    scopus 로고
    • Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus
    • Riely GJ, Kris MG, Zhao B et al. Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus. Clin Cancer Res 2007;13: 5150-5155.
    • (2007) Clin Cancer Res , vol.13 , pp. 5150-5155
    • Riely, G.J.1    Kris, M.G.2    Zhao, B.3
  • 9
    • 77956793546 scopus 로고    scopus 로고
    • Efficacy of trastuzumab in routine clinical practice and after progression for metastatic breast cancer patients: The observational Hermine study
    • Extra JM, Antoine EC, Vincent-Salomon A et al. Efficacy of trastuzumab in routine clinical practice and after progression for metastatic breast cancer patients: The observational Hermine study. The Oncologist 2010;15:799-809.
    • (2010) The Oncologist , vol.15 , pp. 799-809
    • Extra, J.M.1    Antoine, E.C.2    Vincent-Salomon, A.3
  • 10
    • 65349110371 scopus 로고    scopus 로고
    • Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A german breast group 26/breast international group 03-05 study
    • von Minckwitz G, du Bois A, Schmidt M et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A german breast group 26/breast international group 03-05 study. J Clin Oncol 2009; 27:1999-2006.
    • (2009) J Clin Oncol , vol.27 , pp. 1999-2006
    • von Minckwitz, G.1    du Bois, A.2    Schmidt, M.3
  • 11
    • 84887459978 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network: Non-Small Cell Lung Cancer, Version 3. Available at, Accessed September 9
    • National Comprehensive Cancer Network: Non-Small Cell Lung Cancer, Version 3. Available at: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site. Accessed September 9, 2013.
    • (2013)
  • 12
    • 79952711946 scopus 로고    scopus 로고
    • Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: Distinct natural history of patients with tumors harboring theT790Mmutation
    • Oxnard GR, Arcila ME, Sima CS et al. Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: Distinct natural history of patients with tumors harboring theT790Mmutation. Clin Cancer Res 2011;17:1616-1622.
    • (2011) Clin Cancer Res , vol.17 , pp. 1616-1622
    • Oxnard, G.R.1    Arcila, M.E.2    Sima, C.S.3
  • 13
    • 34548457234 scopus 로고    scopus 로고
    • The IASLCLungCancerStaging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
    • Goldstraw P, Crowley J, Chansky K et al. The IASLCLungCancerStaging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2007;2:706-714.
    • (2007) J Thorac Oncol , vol.2 , pp. 706-714
    • Goldstraw, P.1    Crowley, J.2    Chansky, K.3
  • 14
    • 74949110711 scopus 로고    scopus 로고
    • Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in nonsmall- cell lung cancer
    • Jackman D, Pao W, Riely GJ et al. Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in nonsmall- cell lung cancer. J Clin Oncol 2010;28:357-360.
    • (2010) J Clin Oncol , vol.28 , pp. 357-360
    • Jackman, D.1    Pao, W.2    Riely, G.J.3
  • 15
    • 80052485771 scopus 로고    scopus 로고
    • Maintained sensitivity to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer recurring after adjuvant erlotinib or gefitinib
    • Oxnard GR, Janjigian YY, Arcila ME et al. Maintained sensitivity to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer recurring after adjuvant erlotinib or gefitinib. Clin Cancer Res 2011;17: 6322-6328.
    • (2011) Clin Cancer Res , vol.17 , pp. 6322-6328
    • Oxnard, G.R.1    Janjigian, Y.Y.2    Arcila, M.E.3
  • 16
    • 79952259564 scopus 로고    scopus 로고
    • Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay
    • Arcila ME, Oxnard GR, Nafa K et al. Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay. Clin Cancer Res 2011;17:1169-1180.
    • (2011) Clin Cancer Res , vol.17 , pp. 1169-1180
    • Arcila, M.E.1    Oxnard, G.R.2    Nafa, K.3
  • 17
    • 79953118839 scopus 로고    scopus 로고
    • Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
    • 75ra26
    • Sequist LV, Waltman BA, Dias-Santagata D et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011;3:75ra26.
    • (2011) Sci Transl Med , vol.3
    • Sequist, L.V.1    Waltman, B.A.2    Dias-Santagata, D.3
  • 18
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. J Clin Oncol 1982;5:649-655.
    • (1982) J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 19
    • 77954566882 scopus 로고    scopus 로고
    • Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine
    • Dias-Santagata D, Akhavanfard S, David SS et al. Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine. EMBO Mol Med 2010;2: 146-158.
    • (2010) EMBO Mol Med , vol.2 , pp. 146-158
    • Dias-Santagata, D.1    Akhavanfard, S.2    David, S.S.3
  • 20
    • 33746877875 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutation testing in the care of lung cancer patients
    • Sequist LV, Joshi VA, Janne PA et al. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clin Cancer Res 2006;12: 4403s-4408s.
    • (2006) Clin Cancer Res , vol.12
    • Sequist, L.V.1    Joshi, V.A.2    Janne, P.A.3
  • 21
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
    • Eisenhauer EA, Therasse P, Bogaerts J et al. New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer 2009;45:228-247.
    • (2009) Eur J Cancer , vol.45 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 22
    • 33646888233 scopus 로고    scopus 로고
    • Wherenext for gefitinib in patients with lung cancer?
    • Blackhall F, Ranson M, Thatcher N. Wherenext for gefitinib in patients with lung cancer? LancetOncol 2006;7:499-507.
    • (2006) LancetOncol , vol.7 , pp. 499-507
    • Blackhall, F.1    Ranson, M.2    Thatcher, N.3
  • 23
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial
    • Gatzemeier U, Pluzanska A, Szczesna A et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial. J Clin Oncol 2007;25:1545-1552.
    • (2007) J Clin Oncol , vol.25 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 24
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 1
    • Giaccone G, Herbst RS, Manegold C et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 1. J Clin Oncol 2004;22:777-784.
    • (2004) J Clin Oncol , vol.22 , pp. 777-784
    • Giaccone, G.1    Herbst, R.S.2    Manegold, C.3
  • 25
    • 1542713370 scopus 로고    scopus 로고
    • Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 2
    • Herbst RS, Giaccone G, Schiller JH et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial-INTACT 2. J Clin Oncol 2004;22:785-794.
    • (2004) J Clin Oncol , vol.22 , pp. 785-794
    • Herbst, R.S.1    Giaccone, G.2    Schiller, J.H.3
  • 26
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
    • Herbst RS, Prager D, Hermann R et al. TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005;23:5892-5899.
    • (2005) J Clin Oncol , vol.23 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3
  • 27
    • 84863892117 scopus 로고    scopus 로고
    • Randomized phase II trial of erlotinib alone or with carboplatinandpaclitaxel in patientswhowerenever or light former smokers with advanced lung adenocarcinoma: CALGB 30406 Trial
    • Jänne PA, Wang X, Socinski MA et al. Randomized phase II trial of erlotinib alone or with carboplatinandpaclitaxel in patientswhowerenever or light former smokers with advanced lung adenocarcinoma: CALGB 30406 Trial. J Clin Oncol 2012;30:2063-2069.
    • (2012) J Clin Oncol , vol.30 , pp. 2063-2069
    • Jänne, P.A.1    Wang, X.2    Socinski, M.A.3
  • 28
    • 80052972204 scopus 로고    scopus 로고
    • A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer
    • Hirsch FR, Kabbinavar F, Eisen T et al. A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer. J Clin Oncol 2011;29: 3567-3573.
    • (2011) J Clin Oncol , vol.29 , pp. 3567-3573
    • Hirsch, F.R.1    Kabbinavar, F.2    Eisen, T.3
  • 29
    • 58249092152 scopus 로고    scopus 로고
    • Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer
    • Riely GJ, Rizvi NA, Kris MG et al. Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer. J Clin Oncol 2009;27:264-270.
    • (2009) J Clin Oncol , vol.27 , pp. 264-270
    • Riely, G.J.1    Rizvi, N.A.2    Kris, M.G.3
  • 30
    • 84879784343 scopus 로고    scopus 로고
    • Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): A randomised, doubleblind trial
    • Wu Y-L, Lee JS, Thongprasert S et al. Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): A randomised, doubleblind trial. Lancet Oncol 2013;14:777-786.
    • (2013) Lancet Oncol , vol.14 , pp. 777-786
    • Wu, Y.-L.1    Lee, J.S.2    Thongprasert, S.3
  • 31
    • 84887033779 scopus 로고    scopus 로고
    • A randomized phase II study comparing erlotinib (E) versus E alternating with chemotherapy in relapsed non-small cell lung cancer (NSCLC) patients. The NVALT10 study
    • August 28 [Epub ahead of print]
    • Aerts JG, Codrington H, Burgers S et al. A randomized phase II study comparing erlotinib (E) versus E alternating with chemotherapy in relapsed non-small cell lung cancer (NSCLC) patients. The NVALT10 study. Ann Oncol 2013 August 28 [Epub ahead of print].
    • (2013) Ann Oncol
    • Aerts, J.G.1    Codrington, H.2    Burgers, S.3
  • 32
    • 84871955487 scopus 로고    scopus 로고
    • Prospective assessment of continuation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of pemetrexed
    • Yoshimura N, Okishio K, Mitsuoka S et al. Prospective assessment of continuation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of pemetrexed. J Thorac Oncol 2013;8:96-101.
    • (2013) J Thorac Oncol , vol.8 , pp. 96-101
    • Yoshimura, N.1    Okishio, K.2    Mitsuoka, S.3
  • 33
    • 84884955771 scopus 로고    scopus 로고
    • Erlotinib beyond progression study: Randomized phase II study comparing chemotherapy plus erlotinib with chemotherapy alone in EGFR tyrosine kinase inhibitor (TKI)-responsive, non-small cell lung cancer (NSCLC) that subsequently progresses
    • abstr 8114
    • Halmos B, Pennell NA, Otterson GA et al. Erlotinib beyond progression study: Randomized phase II study comparing chemotherapy plus erlotinib with chemotherapy alone in EGFR tyrosine kinase inhibitor (TKI)-responsive, non-small cell lung cancer (NSCLC) that subsequently progresses. J Clin Oncol 2013;31 (suppl):abstr 8114.
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL.
    • Halmos, B.1    Pennell, N.A.2    Otterson, G.A.3
  • 34
    • 73449123757 scopus 로고    scopus 로고
    • Second-line treatments after first-line gefitinib therapy in advanced nonsmall cell lung cancer
    • Wu JY, Shih JY, Yang CH et al. Second-line treatments after first-line gefitinib therapy in advanced nonsmall cell lung cancer. Int J Cancer 2010;126:247-255.
    • (2010) Int J Cancer , vol.126 , pp. 247-255
    • Wu, J.Y.1    Shih, J.Y.2    Yang, C.H.3


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