Acute pulmonary embolism: External validation of an integrated risk stratification model

Chest

Volumn 144, Issue 5, 2013, Pages 1539-1545

  Becattini, Cecilia ^a   Casazza, Franco ^b   Forgione, Chiara ^c   Porro, Fernando ^d   Fadin, Bianca Maria ^e   Stucchi, Alessandra ^f   Lignani, Alessandra ^a   Conte, Luca ^g   Imperadore, Ferdinando ^h   Bongarzoni, Amedeo ^b   Agnelli, Giancarlo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b SAN CARLO BORROMEO HOSPITAL   (Italy)

^c Fondazione Poliambulanza   (Italy)

^d FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^e CREMONA HOSPITAL   (Italy)

^f Nuovo Ospedale S Agostino   (Italy)

^g Ospedale S Maria della Misericordia   (Italy)

^h Ospedale S Maria del Carmine   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOLAMINE; TROPONIN;

ADULT; AGED; ARTICLE; CARDIOGENIC SHOCK; CAUSE OF DEATH; ECHOCARDIOGRAPHY; FEMALE; HAZARD RATIO; HEART LEFT VENTRICLE FAILURE; HEART VENTRICLE PRESSURE; HOSPITALIZATION; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; RISK STRATIFICATION MODEL; STATISTICAL MODEL; SUDDEN DEATH; TISSUE PERFUSION;

EID: 84887434148     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.12-2938     Document Type: Article

References (27)

1. Lloyd-Jones D, Adams RJ, Brown TM, et al; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2010 update: a report from the American Heart Association [published corrections appear in Circulation. 2010;121(12):e260
2. and Circulation. 2011;124(16):e425].
3. Circulation. 2010;121(7):e46-e215.
4. Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet. 1999;353(9162):1386-1389.
5. Laporte S, Mismetti P, Décousus H, et al; RIETE Investigators. Clinical predictors for fatal pulmonary embolism in 15, 520 patients with venous thromboembolism: findings from the Registro Informatizado de la Enfermedad Trom bo-Embo lica venosa (RIETE) Registry. Circulation. 2008;117(13):1711-1716.
6. Lobo JL, Zorrilla V, Aizpuru F, et al. Clinical syndromes and clinical outcome in patients with pulmonary embolism: findings from the RIETE registry. Chest. 2006;130(6):1817-1822.
7. Pollack CV, Schreiber D, Goldhaber SZ, et al. Clinical characteristics, management, and outcomes of patients diagnosed with acute pulmonary embolism in the emergency department: initial report of EMPEROR (Multicenter Emergency Medicine Pulmonary Embolism in the Real World Registry). J Am Coll Cardiol. 2011;57(6):700-706.
8. Agnelli G, Becattini C. Acute pulmonary embolism. N Engl J Med. 2010;363(3):266-274.
9. Jaff MR, McMurtry MS, Archer SL, et al; American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; American Heart Association Council on Peripheral Vascular Disease; American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation 2011;123(16):1788- 1830.
10. Torbicki A, Perrier A, Konstantinides S, et al; ESC Committee for Practice Guidelines (CPG). Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J. 2008;29(18):2276-2315.
11. Konstantinides S, Goldhaber SZ. Pulmonary embolism: risk assessment and management. Eur Heart J. 2012;33(24):3014-3022.
12. Kucher N, Rossi E, De Rosa M, Goldhaber SZ. Prognostic role of echocardiography among patients with acute pulmonary embolism and a systolic arterial pressure of 90 mm Hg or higher. Arch Intern Med. 2005;165(15):1777- 1781.
13. Jiménez D, Díaz G, Molina J, et al. Troponin I and risk stratification of patients with acute nonmassive pulmonary embolism. Eur Respir J. 2008;31(4):847-853.
14. Scridon T, Scridon C, Skali H, Alvarez A, Goldhaber SZ, Solomon SD. Prognostic significance of troponin elevation and right ventricular enlargement in acute pulmonary embolism. Am J Cardiol. 2005;96(2):303-305.
15. Binder L, Pieske B, Olschewski M, et al. N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation. 2005;112(11):1573-1579.
16. Casazza F, Becattini C, Bongarzoni A, et al. Clinical features and short term outcomes of patients with acute pulmonary embolism. The Italian Pulmonary Embolism Registry (IPER). Thromb Res. 2012;130(6):847-852.
17. Douketis JD, Gu CS, Schulman S, Ghirarduzzi A, Pengo V, Prandoni P. The risk for fatal pulmonary embolism after discontinuing anticoagulant therapy for venous thromboembolism. Ann Intern Med. 2007;147(11):766-774.
18. Konstantinides S, Geibel A, Heusel G, Heinrich F, Kasper W; Management Strategies and Prognosis of Pulmonary Embolism-3 Trial Investigators. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. N Engl J Med. 2002;347(15):1143-1150.
19. Steyerberg EW, Vickers AJ, Cook NR, et al. Assessing the performance of prediction models: a framework for traditional and novel measures. Epidemiology. 2010;21(1):128-138.
20. Assistance Publique-Hôpitaux de Paris. PEITHO pulmonary embolism thrombolysis study. NCT00639743. ClinicalTrials. gov. Bethesda, MD: National Institutes of Health; 2008. http://clinicaltrials.gov/ct2/show/NCT00639743. Updated February 6, 2013.
21. Aujesky D, Roy PM, Verschuren F, et al. Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial. Lancet. 2011;378(9785):41-48.
22. Zondag W, Mos IC, Creemers-Schild D, et al; Hestia Study Investigators. Outpatient treatment in patients with acute pulmonary embolism: the Hestia Study. J Thromb Haemost 2011;9(8):1500-1507.
23. Sanchez O, Trinquart L, Colombet I, et al. Prognostic value of right ventricular dysfunction in patients with haemodynamically stable pulmonary embolism: a systematic review. Eur Heart J. 2008;29(12):1569-1577.
24. Becattini C, Vedovati MC, Agnelli G. Prognostic value of troponins in acute pulmonary embolism: a meta-analysis. Circulation. 2007;116(4):427-433.
25. Righini M, Roy PM, Meyer G, Verschuren F, Aujesky D, Le Gal G. The Simplified Pulmonary Embolism Severity Index (PESI): validation of a clinical prognostic model for pulmonary embolism. J Thromb Haemost. 2011;9(10):2115-2117.
26. Becattini C, Agnelli G, Vedovati MC, et al. Multidetector computed tomography for acute pulmonary embolism: diagnosis and risk stratification in a single test. Eur Heart J. 2011;32(13):1657-1663.
27. Klok FA, Mos I C M, Huisman MV. Brain-type natriuretic peptide levels in the prediction of adverse outcome in patients with pulmonary embolism: a systematic review and metaanalysis. Am J Respir Crit Care Med. 2008;178(4):425-430.