Essential hypertension as a result of neurochemical changes at the rostral ventrolateral medulla

Journal of Clinical Neuroscience

Volumn 20, Issue 12, 2013, Pages 1682-1687

  Thomas, Ajith J ^a   Gross, Bradley A ^b   Jacob, Anila ^c   Easwer, Easwer ^d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD VANGUARD MEDICAL ASSOCIATES   (United States)

^d SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Angiotensin; Atherosclerosis; Hypertension; Ischemia; Rostral ventrolateral medulla

Indexed keywords

ADRENERGIC ACTIVITY; ARTICLE; BRAIN; BRAIN ATHEROSCLEROSIS; BRAIN BLOOD FLOW; BRAIN DEPTH STIMULATION; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN REGION; CHRONIC DISEASE; DECOMPRESSION SURGERY; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE PREDISPOSITION; ESSENTIAL HYPERTENSION; HUMAN; NERVE CELL INHIBITION; NERVE CELL STIMULATION; NEUROCHEMISTRY; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; ROSTRAL VENTROLATERAL MEDULLA; VASOCONSTRICTION;

ANGIOTENSIN; ATHEROSCLEROSIS; HYPERTENSION; ISCHEMIA; ROSTRAL VENTROLATERAL MEDULLA;

BRAIN ISCHEMIA; HUMANS; HYPERTENSION; MEDULLA OBLONGATA;

EID: 84887432815     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2013.02.040     Document Type: Article

References (73)

1. J. Conway, N. Boon, and C. Davies Neural and humoral mechanisms involved in blood pressure variability J Hypertens 2 1984 203 208
2. D.J. Reis The brain and hypertension: reflections on 35 years of inquiry into the neurobiology of the circulation Circulation 70 1984 III31 III45
3. J. Ciriello, M.M. Caverson, and C. Polosa Function of the ventrolateral medulla in the control of the circulation Brain Res 396 1986 359 391
4. P.G. Guyenet Role of the ventral medulla oblongata in blood pressure regulation in central regulation of autonomic functions A.D. Loewy, K. Spyer, Central regulation of autonomic functions 1990 Oxford University Press New York 145
5. W.T. Talman Cardiovascular regulation and lesions of the central nervous system Ann Neurol 18 1985 1 13
6. C.A. Ross, D.A. Ruggiero, and D.H. Park Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin J Neurosci 4 1984 474 494
7. P.G. Guyenet, M.K. Sun, and D. Brown Role of GABA and excitatory aminoacids in medullary baroreflex pathways F.R. Calaresu, J. Ciriello, C. Polosa, P. Renaud, Organisation of the autonomic nervous system 1987 Liss New York 215 225
8. S.M. Hilton, and W.S. Redfern A search for brain stem cell groups integrating the defence reaction in the rat J Physiol 378 1986 213 228
9. R.A. Dampney, and E.A. Moon Role of ventrolateral medulla in vasomotor response to cerebral ischemia Am J Physiol 239 1980 H349 H358
10. R.M. McAllen, and R.A. Dampney Vasomotor neurons in the rostral ventrolateral medulla are organized topographically with respect to type of vascular bed but not body region Neurosci Lett 110 1990 91 96
11. C.A. Ross, D.A. Ruggiero, and T.H. Joh Adrenaline synthesizing neurons in the rostral ventrolateral medulla: a possible role in tonic vasomotor control Brain Res 273 1983 356 361
12. S.F. Morrison, P. Ernsberger, and T.A. Milner A glutamate mechanism in the intermediolateral nucleus mediates sympathoexcitatory responses to stimulation of the rostral ventrolateral medulla Prog Brain Res 81 1989 159 169
13. M.K. Sun, J.T. Hackett, and P.G. Guyenet Sympathoexcitatory neurons of rostral ventrolateral medulla exhibit pacemaker properties in the presence of a glutamate-receptor antagonist Brain Res 438 1988 23 40
14. Y.W. Li, Z.Q. Ding, and S.L. Wesselingh Renal and adrenal sympathetic preganglionic neurons in rabbit spinal cord: tracing with herpes simplex virus Brain Res 573 1992 147 152
15. L.W. Swanson Biochemical switching in hypothalamic circuits mediating responses to stress Prog Brain Res 87 1991 181 200
16. R.L. Stornetta, S.F. Morrison, and D.A. Ruggiero Neurons of rostral ventrolateral medulla mediate somatic pressor reflex Am J Physiol 256 1989 R448 R462
17. D.A. Ruggiero, S.L. Cravo, and V. Arango Central control of the circulation by the rostral ventrolateral reticular nucleus: anatomical substrates Prog Brain Res 81 1989 49 79
18. P.G. Guyenet, J.R. Haselton, and M.K. Sun Sympathoexcitatory neurons of the rostroventrolateral medulla and the origin of the sympathetic vasomotor tone Prog Brain Res 81 1989 105 116
19. M.K. Sun, and D.J. Reis Central neural mechanisms mediating excitation of sympathetic neurons by hypoxia Prog Neurobiol 44 1994 197 219
20. N.S. Cherniack, E.M. Adams, and N.R. Prabhakar Integration of cardiorespiratory responses in the ventrolateral medulla Prog Brain Res 81 1989 215 220
21. K. Sagawa, J.M. Ross, and A.C. Guyton Quantitation of cerebral ischemic pressor response in dogs Am J Physiol 200 1961 1164 1168
22. H. Cushing Some experimental and clinical observations concerning states of increased intracranial tension Am J Med Sci 124 1902 374 400
23. C. Dickenson Reappraisal of the Cushing reflex: the most powerful neural blood pressure stabilizing system Clin Sci 79 1990 543 550
24. M. Kumada, R.A. Dampney, and D.J. Reis Profound hypotension and abolition of the vasomotor component of the cerebral ischemic response produced by restricted lesions of medulla oblongata in rabbit. Relationship to the so-called tonic vasomotor center Circ Res 45 1979 63 70
25. B.M. Montgomery The basilar artery hypertensive syndrome Arch Intern Med 108 1961 559 569
26. P. Janetta, R. Segal, and S. Wolfson Jr. Neurogenic hypertension; etiology and surgical treatment. I. Observations in 53 patients Ann Surg 201 1985 391 398
27. D.J. Reis, and N. Doba Hypertension as a localizing sign of mass lesions of brainstem N Engl J Med 287 1972 1355 1356
28. Australian National Health and Medical Research Council Dietary Salt Study Management Committee. Fall in blood pressure with modest reduction in dietary salt intake in mild hypertension. Lancet 1 1989 399 402
29. P.R. Howe, P.F. Rogers, and G.A. Head Limited baroreflex control of heart rate in young stroke-prone spontaneously hypertensive rats J Hypertens 7 1989 69 75
30. E.A. Wilczynski, and F.H. Leenen Dietary sodium intake and age in spontaneously hypertensive rats: effects on blood pressure and sympathetic activity Life Sci 41 1987 707 715
31. E.A. Anderson, C.A. Sinkey, and W.J. Lawton Elevated sympathetic nerve activity in borderline hypertensive humans. Evidence from direct intraneural recordings Hypertension 14 1989 177 183
32. H. Okudera, S. Kobayashi, and K. Kyoshima Remission of essential hypertension following decompression of a giant aneurysm of the right vertebral artery J Clin Neurosci 1 1994 277 279
33. E.C. Vasquez, S.J. Lewis, and K.J. Varner Chronic lesion of rostral ventrolateral medulla in spontaneously hypertensive rats Hypertension 19 1992 II154 II158
34. T. Kagawa, R. Horie, and K. Moritake Effects of long-term cerebral ischemia caused by bilateral carotid artery ligation on the acceleration or the development of hypertension in spontaneously hypertensive rats (SHR) or Wistar-Kyoto rats (WKY) Clin Exp Hypertens A 13 1991 1043 1049
35. F.C. Barone, W.J. Price, and R.F. White Genetic hypertension and increased susceptibility to cerebral ischemia Neurosci Biobehav Rev 16 1992 219 233
36. C. Dickenson, and A. Thoson Vertebral and internal carotid arteries in relation to hypertension and cerebrovascular diseases Lancet 2 1959 46 48
37. J.M. Fein, and W. Frishman Neurogenic hypertension related to vascular compression of the lateral medulla Neurosurgery 6 1980 615 622
38. L.R. Caplan Bilateral distal vertebral artery occlusion Neurology 33 1983 552 558
39. F. Nobili, G. Rodriguez, and S. Marenco Regional cerebral blood flow in chronic hypertension. A correlative study Stroke 24 1993 1148 1153
40. D.W. Droste, M.A. Ritter, and R. Dittrich Arterial hypertension and ischaemic stroke Acta Neurol Scand 107 2003 241 251
41. C. Li, G. Engstrom, and B. Hedblad Blood pressure control and risk of stroke: a population-based prospective cohort study Stroke 36 2005 725 730
42. H.P. Mattle, L. Kappeler, and M. Arnold Blood pressure and vessel recanalization in the first hours after ischemic stroke Stroke 36 2005 264 268
43. T.G. Shaw, K.F. Mortel, and J.S. Meyer Cerebral blood flow changes in benign aging and cerebrovascular disease Neurology 34 1984 855 862
44. L.L. Beason-Held, A. Moghekar, and A.B. Zonderman Longitudinal changes in cerebral blood flow in the older hypertensive brain Stroke 38 2007 1766 1773
45. K.F. Mortel, M.A. Pavol, and S. Wood Prospective studies of cerebral perfusion and cognitive testing among elderly normal volunteers and patients with ischemic vascular dementia and Alzheimer's disease Angiology 45 1994 171 180
46. R. Giuliano, D.A. Ruggiero, and S. Morrison Cholinergic regulation of arterial pressure by the C1 area of the rostral ventrolateral medulla J Neurosci 9 1989 923 942
47. M.I. Phillips Functions of angiotensin in the central nervous system Annu Rev Physiol 49 1987 413 435
48. R.E. Gomez, M.A. Cannata, and T.A. Milner Vasopressinergic mechanisms in the nucleus reticularis lateralis in blood pressure control Brain Res 604 1993 90 105
49. R. Mosqueda-Garcia, T. Inagami, and M. Appalsamy Endothelin as a neuropeptide. Cardiovascular effects in the brainstem of normotensive rats Circ Res 72 1993 20 35
50. R.N. Willette, P.P. Barcas, and A.J. Krieger Endogenous GABAergic mechanisms in the medulla and the regulation of blood pressure J Pharmacol Exp Ther 230 1984 34 39
51. D.I. Lewis, and J.H. Coote Mediation of baroreceptor inhibition of sympathetic nerve activity via both a brainstem and spinal site in rats J Physiol 481 1994 197 205
52. J.M. Wyss, S. Oparil, and W. Sripairojthikoon Neuronal control of the kidney: contribution to hypertension Can J Physiol Pharmacol 70 1992 759 770
53. J. Zanzinger, J. Czachurski, and H. Seller Inhibition of basal and reflex-mediated sympathetic activity in the RVLM by nitric oxide Am J Physiol 268 1995 R958 R962
54. A.M. Allen, S.Y. Chai, and J. Clevers Localization and characterization of angiotensin II receptor binding and angiotensin converting enzyme in the human medulla oblongata J Comp Neurol 269 1988 249 264
55. K.G. Baker, G.M. Halliday, and J.P. Hornung Distribution, morphology and number of monoamine-synthesizing and substance P-containing neurons in the human dorsal raphe nucleus Neuroscience 42 1991 757 775
56. B.K. Siesjo, Q. Zhao, and K. Pahlmark Glutamate, calcium, and free radicals as mediators of ischemic brain damage Ann Thorac Surg 59 1995 1316 1320
57. F.C. Barone, M.Y. Globus, and W.J. Price Endothelin levels increase in rat focal and global ischemia J Cereb Blood Flow Metab 14 1994 337 342
58. M.P. Printz Regulation of the brain angiotensin system: a thesis of multicellular involvement Clin Exp Hypertens A 10 1988 17 35
59. A.M. Allen, G. Paxinos, and M.J. McKinley Localization and characterization of angiotensin II receptor binding sites in the human basal ganglia, thalamus, midbrain pons, and cerebellum J Comp Neurol 312 1991 291 298
60. A.V. Ferguson, and K.M. Wall Central actions of angiotensin in cardiovascular control: multiple roles for a single peptide Can J Physiol Pharmacol 70 1992 779 785
61. S.J. Fluharty, and A.N. Epstein Sodium appetite elicited by intracerebroventricular infusion of angiotensin II in the rat: II. Synergistic interaction with systemic mineralocorticoids Behav Neurosci 97 1983 746 758
62. M.I. Phillips Angiotensin in the brain Neuroendocrinology 25 1978 354 377
63. J.M. Saavedra, L.M. Plunkett, and I.M.A. Correa Quantitative autoradiography of angiotensin and natriuretic factor binding sites in brain nuclei of spontnaeously hypertensive rats J.P. Buckley, C.M. Ferrario, Brain peptides and catecholamines in cardiovascular regulation 1987 Raven Press New York 245
64. M. Remiszewska, Z. Jastrzebski, and H. Czyzewska-Szafran Increased activity of the GABAergic system in selected brain areas after chronic propranolol treatment in spontaneously hypertensive rats Biochem Pharmacol 44 1992 465 470
65. F.C. Luft Angiotensin, inflammation, hypertension, and cardiovascular disease Curr Hypertens Rep 3 2001 61 67
66. S. Sasaki, and R.A. Dampney Tonic cardiovascular effects of angiotensin II in the ventrolateral medulla Hypertension 15 1990 274 283
67. K. Kumagai, and I.A. Reid Losartan inhibits sympathetic and cardiovascular responses to carotid occlusion Hypertension 23 1994 827 831
68. J.J. Buccafusco, C.A. Lapp, and K.L. Westbrooks Role of medullary I1-imidazoline and alpha 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine analogs in conscious spontaneously hypertensive rats J Pharmacol Exp Ther 273 1995 1162 1171
69. W.Z. Wang, W.J. Yuan, and D.F. Su Blockade of N-methyl-D-aspartate receptors within the rostral ventrolateral medulla antagonizes clonidine-induced cardiovascular effects Auton Neurosci 109 2003 21 28
70. A.K. Mandal, P.Y. Zhong, and K.J. Kellar Ventrolateral medulla: an important site of action for the hypotensive effect of drugs that activate serotonin-1A receptors J Cardiovasc Pharmacol 15 1990 S49 S60
71. A.K. Mandal, K.J. Kellar, and R.A. Gillis The role of serotonin-1A receptor activation and alpha-1 adrenoceptor blockade in the hypotensive effect of 5-methyl-urapidil J Pharmacol Exp Ther 257 1991 861 869
72. D.B. Averill, T. Tsuchihashi, and M.C. Khosla Losartan, nonpeptide angiotensin II-type 1 (AT1) receptor antagonist, attenuates pressor and sympathoexcitatory responses evoked by angiotensin II and L-glutamate in rostral ventrolateral medulla Brain Res 665 1994 245 252
73. A.M. Strack, W.B. Sawyer, and K.B. Platt CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labeling with pseudorabies virus Brain Res 491 1989 274 296