Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g)

FEBS Letters

Volumn 587, Issue 22, 2013, Pages 3668-3674

  Kim, Jong Tae ^a   Lee, Seon Jin ^a   Kim, Bo Yeon ^a   Lee, Chul Ho ^a   Yeom, Young Il ^a   Choe, Yong Kyung ^a   Yoon, Do Young ^b   Chae, Suhn Kee ^c   Kim, Jung Woo ^c   Yang, Young ^d   Lim, Jong Seok ^d   Lee, Hee Gu ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Konkuk University   (South Korea)

^c PaiChai University   (South Korea)

^d Sookmyung Women's University   (South Korea)

Author keywords

Apoptosis; Caspase; DNase; eIF3g; Translation initiation factor

Indexed keywords

CASPASE; CISPLATIN; DEOXYRIBONUCLEASE; INITIATION FACTOR 3; PROTEIN EIF3G; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; TRANSLATION INITIATION;

APOPTOSIS; CASPASE; DNASE; EIF3G; TRANSLATION INITIATION FACTOR;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID MOTIFS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL NUCLEUS; DEOXYRIBONUCLEASES; DNA CLEAVAGE; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-3; HUMANS; PEPTIDE FRAGMENTS; PROTEOLYSIS;

EUKARYOTA;

EID: 84887408732     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.09.027     Document Type: Article

References (21)

1. E.M. Hannig Protein synthesis in eukaryotic organisms: new insights into the function of translation initiation factor eIF-3 Bioessays 17 1995 915 919
2. A.G. Hinnebusch EIF3: a versatile scaffold for translation initiation complexes Trends Biochem. Sci. 31 2006 553 562
3. J.W. Hershey, K. Asano, T. Naranda, H.P. Vornlocher, P. Hanachi, and W.C. Merrick Conservation and diversity in the structure of translation initiation factor EIF3 from humans and yeast Biochimie 78 1996 903 907
4. L. Cuchalova, T. Kouba, A. Herrmannova, I. Danyi, W.L. Chiu, and L. Valasek The RNA recognition motif of eukaryotic translation initiation factor 3g (eIF3g) is required for resumption of scanning of posttermination ribosomes for reinitiation on GCN4 and together with eIF3i stimulates linear scanning Mol. Cell. Biol. 30 2010 4671 4686
5. K.S. Browning, D.R. Gallie, J.W. Hershey, A.G. Hinnebusch, U. Maitra, W.C. Merrick, and C. Norbury Unified nomenclature for the subunits of eukaryotic initiation factor 3 Trends Biochem. Sci. 26 2001 284
6. G.L. Mayeur, C.S. Fraser, F. Peiretti, K.L. Block, and J.W. Hershey Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 Eur. J. Biochem. 270 2003 4133 4139
7. C. Zhou, F. Arslan, S. Wee, S. Krishnan, A.R. Ivanov, A. Oliva, J. Leatherwood, and D.A. Wolf PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes BMC Biol. 3 2005 14
8. L. Phan, X. Zhang, K. Asano, J. Anderson, H.P. Vornlocher, J.R. Greenberg, J. Qin, and A.G. Hinnebusch Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5 Mol. Cell. Biol. 18 1998 4935 4946
9. M.J. Clemens, M. Bushell, I.W. Jeffrey, V.M. Pain, and S.J. Morley Translation initiation factor modifications and the regulation of protein synthesis in apoptotic cells Cell Death Differ. 7 2000 603 615
10. M. Bushell, D. Poncet, W.E. Marissen, H. Flotow, R.E. Lloyd, M.J. Clemens, and S.J. Morley Cleavage of polypeptide chain initiation factor eIF4GI during apoptosis in lymphoma cells: characterisation of an internal fragment generated by caspase-3-mediated cleavage Cell Death Differ. 7 2000 628 636
11. W.E. Marissen, and R.E. Lloyd Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells Mol. Cell. Biol. 18 1998 7565 7574
12. A. Gradi, Y.V. Svitkin, H. Imataka, and N. Sonenberg Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection Proc. Natl. Acad. Sci. USA 95 1998 11089 11094
13. M. Bushell, W. Wood, M.J. Clemens, and S.J. Morley Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis Eur. J. Biochem. 267 2000 1083 1091
14. S. Satoh, M. Hijikata, H. Handa, and K. Shimotohno Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alpha Biochem. J. 342 Pt 1 1999 65 70
15. J.T. Kim Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g) FEBS Lett. 580 2006 6375 6383
16. U. Fischer, R.U. Janicke, and K. Schulze-Osthoff Many cuts to ruin: a comprehensive update of caspase substrates Cell Death Differ. 10 2003 76 100
17. W.C. Earnshaw, L.M. Martins, and S.H. Kaufmann Mammalian caspases: structure, activation, substrates, and functions during apoptosis Annu. Rev. Biochem. 68 1999 383 424
18. L. ElAntak, A.G. Tzakos, N. Locker, and P.J. Lukavsky Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40S ribosomal subunit J. Biol. Chem. 282 2007 8165 8174
19. C.S. Fraser, J.Y. Lee, G.L. Mayeur, M. Bushell, J.A. Doudna, and J.W. Hershey The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40S ribosomal subunits in vitro J. Biol. Chem. 279 2004 8946 8956
20. N. Machuy, B. Thiede, K. Rajalingam, C. Dimmler, O. Thieck, T.F. Meyer, and T. Rudel A global approach combining proteome analysis and phenotypic screening with RNA interference yields novel apoptosis regulators Mol. Cell. Proteomics 4 2005 44 55
21. A. Herrmannova Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly Nucleic Acids Res. 40 2012 2294 2311