Microfluidic chip capillary electrophoresis coupled with electrochemiluminescence for enantioseparation of racemic drugs using central composite design optimization

Electrophoresis

Volumn 34, Issue 20-21, 2013, Pages 2962-2969

  Guo, Wen Peng ^a,b   Rong, Zhi Bin ^a,c   Li, Ying Hong ^a   Fung, Ying Sing ^b   Gao, Guo Quan ^a   Cai, Zhi Ming ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c Shijiazhuang Maternal and Child Health Care Hospital   (China)

Author keywords

Central composite design; Enantioseparation; Ferrofluid valve; Microchip CE; Spiral channel

Indexed keywords

BODY FLUIDS; CAPILLARY ELECTROPHORESIS; CHIRALITY; INTEGRATED CIRCUIT DESIGN; MICROFLUIDICS; MICROPROCESSOR CHIPS;

ANISODAMINE; ATENOLOL; CENTRAL COMPOSITE DESIGNS; ENANTIOSEPARATIONS; FERROFLUID VALVE; HUMAN URINE; METOPROLOL; MICROCHIP-CE; MICROFLUIDIC-CHIPS; SPIRAL CHANNEL;

MICROFLUIDIC CHIPS;

ANISODAMINE; ATENOLOL; METOPROLOL; POLY(METHYL METHACRYLATE);

ANALYTICAL EQUIPMENT; ARTICLE; CAPILLARY ELECTROPHORESIS; CHEMOLUMINESCENCE; CHIRALITY; CONTROLLED STUDY; DILUTION; ELECTROCHEMILUMINESCENCE; ENANTIOMER; EQUIPMENT DESIGN; HUMAN; LIMIT OF DETECTION; MICROCHIP; MICROFLUIDIC CHIP CAPILLARY ELECTROPHORESIS; MICROTECHNOLOGY; PROCESS OPTIMIZATION; PRODUCT RECOVERY; REPRODUCIBILITY; URINALYSIS;

CENTRAL COMPOSITE DESIGN; ENANTIOSEPARATION; FERROFLUID VALVE; MICROCHIP-CE; SPIRAL CHANNEL;

ANTI-ARRHYTHMIA AGENTS; ATENOLOL; ELECTROPHORESIS, MICROCHIP; EQUIPMENT DESIGN; HUMANS; LIMIT OF DETECTION; LUMINESCENT MEASUREMENTS; METOPROLOL; REPRODUCIBILITY OF RESULTS; SOLANACEOUS ALKALOIDS; STEREOISOMERISM;

EID: 84887403003     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201300238     Document Type: Article

References (27)

1. Legido-Quigley, C., Marlin, N., Melin, V., Manz, A., Smith, N., Electrophoresis 2003, 24, 917-944.
2. Tsioupi, D., Stefan-vanStaden, R., Kapnissi-Christodoulou, C. P., Electrophoresis 2013, 34, 178-204.
3. Kahle, K. A., Foley, J. P., Electrophoresis 2007, 28, 2503-2526.
4. Zaidi, S. A., Han, K., Hwang, D. G., Cheong, W. J., Electrophoresis 2010, 31, 1019-1028.
5. Gong, Y. X., Li, S. P., Li, P., Liu, J. J., Wang, Y. T., J. Chromatogr. A 2004, 1055, 215-221.
6. Suntornsuk, L., Anal. Bioanal. Chem. 2010, 398, 29-52.
7. Rudaz, S., Cherkaoui, S., Gauvrit, J. Y., Lantéri, P., Veuthey, J. L., Electrophoresis 2001, 22, 3316-3326.
8. Mangelings, D., Heyden, Y. V., J. Sep. Sci. 2008, 31, 1252-1273.
9. Schlabach, T. D., Excoffier, J. L., J. Chromatogr. A 1988, 439, 173-184.
10. Capella-Peiró, M. E., Font-Rubert, M., Àlvarez-Rodríguez, L., Esteve-Romero, J., Durgbanshi, A., Bose, D., J. Liq. Chromatogr. Related Technol. 2007, 30, 2975-2988.
11. Li, X., Zhu, D., You, T., Electrophoresis 2011, 32, 2139-2147.
12. Hu, X., Xu, D., Liu, S., Liu, Z., Liu, S., Luminescence 2009, 24, 79-83.
13. Peng, X., Wang, Z., Li, J., Le, G., Shi, Y., Anal. Lett. 2008, 41, 1184-1199.
14. Bhushan, R., Agarwal, C., J. Planar. Chromatogr. 2010, 23, 7-13.
15. Bosch, M. P., Reijenga, J. C., Global J. Anal. Chem. 2010, 3, 189-195.
16. Yang, H., Li, X., Yang, F., Feng, J., Lin, M., Chen, Z., Microchim. Acta 2011, 175, 193-199.
17. Nagl, S., Schulze, P., Ohla, S., Beyreiss, R., Gitlin, L., Belder, D., Anal. Chem. 2011, 83, 3232-3238.
18. Chen, J., Yung, R. J., Electrophoresis 2007, 28, 975-980.
19. Qiu, H., Yin, X., Yan, J., Zhao, X., Yang, X., Wang, E., Electrophoresis 2005, 26, 687-693.
20. Kriikku, P., Grass, B., Hokkanen, A., Stuns, I., Siren, H., Electrophoresis 2004, 25, 1687-1694.
21. Guo, W. P., Lau, K. M., Fung, Y. S., Electrophoresis 2010, 31, 3044-3052.
22. Guo, W. P., Fung, Y. S., Electrophoresis 2011, 32, 3437-3445.
23. Gao, Y., Shen, Z., Dai, Z., Lin, B. C., Electrophoresis 2005, 26, 4774-4779.
24. Weibel, D. B., Kruithof, M., Potenta, S., Sia, S. K., Lee, A., Whitesides, G. M., Anal. Chem. 2005, 77, 4726-4733.
25. Wang, J. W., Zhang, X. J., Pi, F. F., Wang, X. X., Yang, N. J., Electrochim. Acta 2009, 54, 2379-2384.
26. Sanchez-Hernandez, L., Castro, M., Marina, M., Crego, A., Electrophoresis 2012, 33, 228-242.
27. Miyake, O., Yoshimura, K., Tsujihata, M., Yoshioka, T., Urology 1999, 53, 1229-1234.