Efficacy of actovegin in the treatment of elderly patients with vascular mild cognitive impairment

Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova

Volumn 2013, Issue 7, 2013, Pages 69-76

  Mikhailova, N M ^a   Selezneva, N D ^a   Kalyn, Ya B ^a   Roshchina, I F ^a   Gavrilova, S I ^a  

^a MENTAL HEALTH RESEARCH CENTER   (Russian Federation)

Author keywords

Actovegin; Cerebrovascular disease; Mild cognitive impairment

Indexed keywords

ACTOVEGIN; CENTRAL STIMULANT AGENT; DRUG DERIVATIVE; HEME;

AGED; ARTICLE; ASTHENIA; BOSTON NAMING TEST; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL GLOBAL IMPRESSION SCALE; CLOCK DRAWING TEST; DEPRESSION; DISEASE ASSESSMENT; DRUG EFFICACY; FEMALE; HAMILTON DEPRESSION RATING SCALE; HUMAN; MALE; MATTIS DEMENTIA SCALE; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; PERSONALITY TEST; WORD LIST RECALL; COGNITION; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FOLLOW UP; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PSYCHOLOGICAL RATING SCALE; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CENTRAL NERVOUS SYSTEM STIMULANTS; CEREBROVASCULAR DISORDERS; COGNITION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLOW-UP STUDIES; HEME; HUMANS; MALE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME;

EID: 84887374253     PISSN: 19977298     EISSN: 23094729     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Kanowsky S., Kinzler E., Lehman E. et al. Confirmed clinical efficacy of actovegin in elderly patients with organic brain syndrome. Pharmacopsychiatry 1995; 28: 125-133.
2. Lopez O., Jagust W., De Cosky S. et al. Prevalence and Classification of Mild Cognitive Impairment in the Cardiovascular Health Study. Arch Neurol 2003; 60: 10: 1385-1389.
3. Meyer A. Is Mild Cognitive Impairement Prodromal for Vascular Dementia Like Alzheimer's Disease? Stroke 2002; 33: 1981-1985.
4. Oswald W.D., Steger W., Oswald B., Kuntz G. Die Verbesserung fluider Kognitiver Leistungen mit Actovegin-Infusionen bei Alterpatienten mit leichtem bis mittelschwerem organischem Psychosyndrom. Z Gerontopsychol- Psychiatr 1992; 5: 251-266.
5. Reisberg B., Ferris S.H., de Leon M.J., Crook T. The global deterioration scale for assessment of primary degenerative dementia. Fm J Psychiatry 1982; 139: 1136-1139.
6. Saletu B., Gruenberger J., Linzmayer L. et al. EEG brain mapping and psychometry in age-associated memory impairment after 2 weeks infusions with the hemoderivative Actovegin: double blind placebo controlled trials. Neuropsychobiology 1991; 24: 135-145.