Impact of treatment exposures on cardiovascular risk and insulin resistance in childhood cancer survivors

Cancer Epidemiology Biomarkers and Prevention

Volumn 22, Issue 11, 2013, Pages 1954-1963

  Baker, K Scott ^a   Chow, Eric J ^a   Goodman, Pamela J ^a   Leisenring, Wendy M ^a   Dietz, Andrew C ^b   Perkins, Joanna L ^c   Chow, Lisa ^d   Sinaiko, Alan ^d   Moran, Antoinette ^d   Petryk, Anna ^d   Steinberger, Julia ^d  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Children's Hospitals   (United States)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE; DNA TOPOISOMERASE INHIBITOR; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; PLATINUM; STEROID; TRIACYLGLYCEROL;

ACUTE LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER SURVIVOR; CARDIOVASCULAR RISK; CHILD; CHILDHOOD CANCER; CHILDHOOD LEUKEMIA; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; EXPOSURE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHOOL CHILD; SIBLING; SOLID TUMOR; STEROID THERAPY; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE;

ADOLESCENT; ANTINEOPLASTIC AGENTS; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INSULIN RESISTANCE; LINEAR MODELS; MALE; NEOPLASMS; RADIATION INJURIES; RADIOTHERAPY; RISK FACTORS; SURVIVORS; TREATMENT OUTCOME;

EID: 84887293758     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-13-0610     Document Type: Article

References (30)

1. Armstrong GT, Liu Q, Yasui Y, Neglia JP, Leisenring W, Robison LL, et al. Late mortality among 5-year survivors of childhood cancer: A summary from the Childhood Cancer Survivor Study. J Clin Oncol 2009;27:2328-38.
2. Mertens AC, Liu Q, Neglia JP, Wasilewski K, Leisenring W, Armstrong GT, et al. Cause-specific late mortality among 5-year survivors of childhood cancer: The Childhood Cancer Survivor Study. J Natl Cancer Inst 2008;100:1368-79.
3. Reulen RC, Winter DL, Frobisher C, Lancashire ER, Stiller CA, Jenney ME, et al. Long-term cause-specific mortality among survivors of childhood cancer. JAMA 2010;304:172-9.
4. Mulrooney DA, Yeazel MW, Kawashima T, Mertens AC, Mitby P, Stovall M, et al. Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort. Bmj 2009;339:b4606.
5. Talvensaari KK, Lanning M, Tapanainen P, Knip M. Long-term survivors of childhood cancer have an increased risk of manifesting the metabolic syndrome. J Clin Endocrinol Metab 1996;81:3051-5.
6. Talvensaari K, Knip M. Childhood cancer and later development of the metabolic syndrome. Ann Med 1997;29:353-5.
7. Nuver J, Smit AJ, Postma A, Sleijfer DT, Gietema JA. Themetabolic syndrome in long-term cancer survivors, an important target for secondary preventive measures. Cancer Treat Rev 2002;28: 195-214.
8. Oeffinger KC, Mertens AC, Sklar CA, Yasui Y, Fears T, Stovall M, et al. Obesity in adult survivors of childhood acute lymphoblastic leukemia: A report from the childhood cancer survivor study. J Clin Oncol 2003;17:1359-65.
9. Gurney JG, Sibley SD, O'Leary M, Ness KK, Baker KS. Metabolic syndrome and growth hormone deficiency in adult survivors of childhood leukemia. Pediatr Blood Cancer 2005;44:565.
10. Farooki A, Schneider SH. Insulin resistance and cancer-related mortality. J Clin Oncol 2007;25:1628-9.
11. Steinberger J, Sinaiko AR, Kelly AS, Leisenring WM, Steffen LM, Goodman P, et al. Cardiovascular risk and insulin resistance in childhood cancer survivors. J Pediatr 2012;160:494-9.
12. Moran A, Jacobs DR, Steinberger J, Hong CP, Prineas R, Luepker R, et al. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999;48:2039-44.
13. Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediatr Adolesc Med 2003;157:821-7.
14. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002;287:356-9.
15. Breiman L, Friedman JH, Olshen RA, Stone CJ. Classification and regression trees. Belmont, CA: Wadsworth International Group; 1984.
16. Hudson MM, Neglia JP, Woods WG, Sandlund JT, Pui CH, Kun LE, et al. Lessons from the past: opportunities to improve childhood cancer survivor care through outcomes investigations of historical therapeutic approaches for pediatric hematological malignancies. Pediatr Blood Cancer 2012;58:334-43.
17. Green DM, Kun LE, Matthay KK, Meadows AT, Meyer WH, Meyers PA, et al. Relevance of historical therapeutic approaches to the contemporary treatment of pediatric solid tumors. Pediatr Blood Cancer 2013; 60:1083-94.
18. Gurney JG, Ness KK, Sibley SD, O'Leary M, Dengel DR, Lee JM, et al. Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia. Cancer 2006; 107:1303-12.
19. Feldman DR, Schaffer WL, Steingart RM. Late cardiovascular toxicity following chemotherapy for germ cell tumors. J Natl Compr Cancer Netw 2012;10:537-44.
20. Fung C, Vaughn DJ. Complications associated with chemotherapy in testicular cancer management. Nat Rev Urol 2011;8:213-22.
21. Gospodarowicz M. Testicular cancer patients: considerations in long-term follow-up. Hematol Oncol Clin North Am 2008;22: 245-55.
22. Haugnes HS, Aass N, Fossa SD, Dahl O, Klepp O, Wist EA, et al. Components of the metabolic syndrome in long-term survivors of testicular cancer. Ann Oncol 2007;18:241-8.
23. Ness KK, Wall MM, Oakes JM, Robison LL, Gurney JG. Physical performance limitations and participation restrictions among cancer survivors: A population-based study. Ann Epidemiol 2006;16: 197-205.
24. Ness KK, Bhatia S, Baker KS, Francisco L, Carter A, Forman SJ, et al. Performance limitations and participation restrictions among childhood cancer survivors treated with hematopoietic stem cell transplantation: The bone marrow transplant survivor study. Arch Pediatr Adolesc Med 2005;159:706-13.
25. Ness KK, Hudson MM, Pui CH, Green DM, Krull KR, Huang TT, et al. Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: Associations with physical performance and chemotherapy doses. Cancer 2012;118:828-38.
26. Ness KK, Baker KS, Dengel DR, Youngren N, Sibley S, Mertens AC, et al. Body composition, muscle strength deficits and mobility limitations in adult survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2007;49:975-81.
27. Ness KK, Morris EB, Nolan VG, Howell CR, Gilchrist LS, Stovall M, et al. Physical performance limitations among adult survivors of childhood brain tumors. Cancer 2010;116:3034-44.
28. Sinaiko AR, Steinberger J, Moran A, Hong CP, Prineas RJ, Jacobs DR Jr. Influence of insulin resistance and body mass index at age 13 on systolic blood pressure, triglycerides, and high-density lipoprotein cholesterol at age 19. Hypertension 2006;48:730-6.
29. Rock CL, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya KS, Schwartz AL, et al. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin 2012;62:243-74.
30. USDA Center for Nutrition Policy and Promotion. Dietary guidelines for Americans, 2010 [cited 2013May 30]; Available from: www.cnpp.usda.gov/dgas2010- policydocument.htm.