Fatal oxaliplatin-induced thrombotic thrombocytopenic purpura: A case report

Clinical Colorectal Cancer

Volumn 12, Issue 4, 2013, Pages 294-296

  Baretta, Zora ^a   Falci, Cristina ^a   Piva, Elisa ^b   Conte, Pierfranco ^a,b  

^a VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Colon cancer; Oxaliplatin; TTP

Indexed keywords

ANTIHISTAMINIC AGENT; BENZODIAZEPINE DERIVATIVE; CAPECITABINE; FLUOROURACIL; FOLINIC ACID; FRESH FROZEN PLASMA; HEMOGLOBIN; IMMUNOGLOBULIN G; IRINOTECAN; METHYLPREDNISOLONE; OXALIPLATIN; PARACETAMOL; STEROID; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

AGED; ARTICLE; AUTOPSY; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER STAGING; CANCER SURGERY; CASE REPORT; COLON ADENOCARCINOMA; COLON METASTASIS; COLON RESECTION; COMPUTER ASSISTED TOMOGRAPHY; DRUG FATALITY; DRUG MEGADOSE; DYSPNEA; ERYTHROCYTE TRANSFUSION; FEVER; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; LUNG METASTASIS; LYMPH NODE METASTASIS; MALE; MULTIPLE CYCLE TREATMENT; PLASMA TRANSFUSION; PLASMAPHERESIS; SEIZURE; THROMBOCYTE COUNT; THROMBOTIC THROMBOCYTOPENIC PURPURA;

COLON CANCER; OXALIPLATIN; TTP;

AGED; ANTINEOPLASTIC AGENTS; COLONIC NEOPLASMS; FATAL OUTCOME; HUMANS; MALE; ORGANOPLATINUM COMPOUNDS; PURPURA, THROMBOTIC THROMBOCYTOPENIC;

EID: 84887275923     PISSN: 15330028     EISSN: 19380674     Source Type: Journal    
DOI: 10.1016/j.clcc.2013.09.002     Document Type: Article

References (12)

1. J.N. George How I treat patients with thrombotic thrombocytopenic purpura: 2010 Blood 116 2010 4060 4069
2. J. Moake Thrombotic thrombocytopenia purpura (TTP) and other thrombotic microangiopathies Best Pract Res Clin Haematol 22 2009 567 576
3. A.C. Regierer, D. Kuehnhardt, and C.O. Schulz Breast cancer-associated thrombotic microangiopathy Breast Care (Basel) 6 2011 441 445
4. R. El-Ghazal, N. Podoltsev, and P. Marks Mitomycin-C-induced thrombotic thrombocytopenic purpura/hemolytic uremic syndrome: cumulative toxicity of an old drug in a new era Clin Colorectal Cancer 10 2011 142 145
5. M. Zupancic, P.C. Shah, and F. Shah-Khan Gemcitabine-associated thrombotic thrombocytopenic purpura Lancet Oncol 8 2007 634 641
6. J.A. Blake-Haskins, R.J. Lechleider, and R.J. Kreitman Thrombotic microangiopathy with targeted cancer agents Clin Cancer Res 17 2011 5858 5866
7. I. Dahabreh, G. Tsoutsos, and D. Tseligas Hemolytic uremic syndrome following the infusion of oxaliplatin: case report BMC Clin Pharmacol 6 2006 5
8. J. Niu, and M.P. Mims Oxaliplatin-induced thrombotic thrombocytopenic purpura: case report and literature review J Clin Oncol 30 2012 e312 e314
9. J. Thachil Causes of thrombotic thrombocytopenic purpura Lancet Oncol 8 2007 757 758
10. G.A. Rock, K.H. Shumak, and N.A. Buskard Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group N Engl J Med 325 1991 393 397
11. M.A. Elliott, L. Letendre, and D.A. Gastineau Cancer-associated microangiopathic hemolytic anemia with thrombocytopenia: an important diagnostic consideration Eur J Haematol 85 2010 43 50
12. M.A. Howard, L.A. Williams, and D.R. Terrell Complications of plasma exchange in patients treated for clinically suspected thrombotic thrombocytopenic purpura-hemolytic uremic syndrome Transfusion 46 2006 154 156