메뉴 건너뛰기




Volumn 7, Issue 10, 2013, Pages

Natural Terpenoids from Ambrosia Species Are Active In Vitro and In Vivo against Human Pathogenic Trypanosomatids

Author keywords

[No Author keywords available]

Indexed keywords

BENZNIDAZOLE; CORDILIN; CUMANIN; DAUCOSTEROL; PSILOSTACHYIN; TERPENOID; UNCLASSIFIED DRUG;

EID: 84887273049     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0002494     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 84892320313 scopus 로고    scopus 로고
    • Natural products and drug discovery
    • In: Zhang L, Demain A, editors New Jersey: Humana Press
    • Demain A, Zhang L (2005) Natural products and drug discovery. In: Zhang L, Demain A, editors. Natural Products. Drug Discovery and Therapeutic Medicine. New Jersey: Humana Press. pp. 3-29.
    • (2005) Natural Products. Drug Discovery and Therapeutic Medicine , pp. 3-29
    • Demain, A.1    Zhang, L.2
  • 2
    • 79952937652 scopus 로고    scopus 로고
    • World Health Organization Available:. Accessed in December 2012
    • World Health Organization (2010) First WHO report on neglected tropical diseases. Available: http://www.who.int/neglected_diseases/2010report/en/. Accessed in December 2012.
    • (2010) First WHO report on neglected tropical diseases
  • 3
    • 84889584672 scopus 로고    scopus 로고
    • Chagas disease (American trypanosomiasis)
    • World Health Organization
    • World Health Organization (2012) Chagas disease (American trypanosomiasis). Fact sheet pp. 340 Available: http://www.who.int/mediacentre/factsheets/fs340/en/index.html. Accessed in December 2012.
    • (2012) Fact Sheet , pp. 340
  • 4
    • 84887282424 scopus 로고    scopus 로고
    • Argentina: more action needed
    • Drugs for Neglected Diseases Initiative
    • Drugs for Neglected Diseases Initiative (2010) Argentina: more action needed. Newsletter 19: 5.
    • (2010) Newsletter , vol.19 , pp. 5
  • 5
    • 79251601146 scopus 로고    scopus 로고
    • Control of the Leishmaniases. Report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22-26 March 2010
    • World Health Organization
    • World Health Organization (2010) Control of the Leishmaniases. Report of a meeting of the WHO Expert Committee on the Control of Leishmaniases, Geneva, 22-26 March 2010. WHO Tech Rep Ser 949: 1-186.
    • (2010) WHO Tech Rep Ser , vol.949 , pp. 1-186
  • 6
    • 0344211515 scopus 로고    scopus 로고
    • Characterization of human infection by Leishmania spp. in the Northwest of Argentina: immune response, double infection with Trypanosoma cruzi and species of Leishmania involved
    • Frank FM, Fernandez MM, Taranto NJ, Cajal SP, Margni RA, et al. (2003) Characterization of human infection by Leishmania spp. in the Northwest of Argentina: immune response, double infection with Trypanosoma cruzi and species of Leishmania involved. Parasitology 126: 31-39.
    • (2003) Parasitology , vol.126 , pp. 31-39
    • Frank, F.M.1    Fernandez, M.M.2    Taranto, N.J.3    Cajal, S.P.4    Margni, R.A.5
  • 7
    • 56949087307 scopus 로고    scopus 로고
    • Epidemiological aspects of cutaneous leishmaniasis in the Iguazú falls area of Argentina
    • Salomón OD, Acardi SA, Liotta DJ, Fernández MS, Lestanic E, et al. (2009) Epidemiological aspects of cutaneous leishmaniasis in the Iguazú falls area of Argentina. Acta Trop 109: 5-11.
    • (2009) Acta Trop , vol.109 , pp. 5-11
    • Salomón, O.D.1    Acardi, S.A.2    Liotta, D.J.3    Fernández, M.S.4    Lestanic, E.5
  • 8
    • 77953082627 scopus 로고    scopus 로고
    • Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches
    • Urbina JA, (2010) Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches. Acta Trop 115: 55-68.
    • (2010) Acta Trop , vol.115 , pp. 55-68
    • Urbina, J.A.1
  • 9
    • 0003961250 scopus 로고    scopus 로고
    • Drugs for Neglected Diseases Initiative Current treatments. Available:. Accessed in April
    • Drugs for Neglected Diseases Initiative. Leishmaniasis. Current treatments. Available: http://www.dndi.org/diseases-projects/diseases/vl/current-treatment.html. Accessed in April 2013.
    • (2013) Leishmaniasis
  • 10
    • 34250697565 scopus 로고    scopus 로고
    • Modern synthesis efforts toward biologically active terpenes
    • Maimone TJ, Baran PS, (2007) Modern synthesis efforts toward biologically active terpenes. Nat Chem Biol 3: 396-407.
    • (2007) Nat Chem Biol , vol.3 , pp. 396-407
    • Maimone, T.J.1    Baran, P.S.2
  • 11
    • 84892352172 scopus 로고    scopus 로고
    • Terpenoids as therapeutic drugs and pharmaceutical agents
    • In: Zhang L, Demain A, editors. Natural Products New Jersey: Humana Press
    • Wang G, Tang W, Bidigare R (2005) Terpenoids as therapeutic drugs and pharmaceutical agents. In: Zhang L, Demain A, editors. Natural Products. Drug Discovery and Therapeutic Medicine. New Jersey: Humana Press. pp. 197-227.
    • (2005) Drug Discovery and Therapeutic Medicine , pp. 197-227
    • Wang, G.1    Tang, W.2    Bidigare, R.3
  • 12
    • 84865957532 scopus 로고    scopus 로고
    • In vitro and in vivo studies of the trypanocidal activity of four terpenoid derivatives against Trypanosoma cruzi
    • Ramírez-Macías I, Marín C, Chahboun R, Messouri I, Olmo F, et al. (2012) In vitro and in vivo studies of the trypanocidal activity of four terpenoid derivatives against Trypanosoma cruzi. Am J Trop Med Hyg 87: 481-488.
    • (2012) Am J Trop Med Hyg , vol.87 , pp. 481-488
    • Ramírez-Macías, I.1    Marín, C.2    Chahboun, R.3    Messouri, I.4    Olmo, F.5
  • 13
    • 84859781734 scopus 로고    scopus 로고
    • Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum D.C
    • Ganfon H, Bero J, Tchinda AT, Gbaguidi F, Gbenou J, et al. (2012) Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum D.C. J Ethnopharmacol 141: 411-417.
    • (2012) J Ethnopharmacol , vol.141 , pp. 411-417
    • Ganfon, H.1    Bero, J.2    Tchinda, A.T.3    Gbaguidi, F.4    Gbenou, J.5
  • 14
    • 84859789562 scopus 로고    scopus 로고
    • Terpenes from Copaifera demonstrated in vitro antiparasitic and synergic activity
    • Izumi E, Ueda-Nakamura T, Veiga VF Jr, Pinto AC, Nakamura CV, (2012) Terpenes from Copaifera demonstrated in vitro antiparasitic and synergic activity. J Med Chem 55: 2994-3001.
    • (2012) J Med Chem , vol.55 , pp. 2994-3001
    • Izumi, E.1    Ueda-Nakamura, T.2    Veiga Jr., V.F.3    Pinto, A.C.4    Nakamura, C.V.5
  • 15
    • 80052031355 scopus 로고    scopus 로고
    • Antileishmanial sesquiterpene lactones from Pseudelephantopus spicatus, a traditional remedy from the Chayahuita Amerindians (Peru) Part III
    • Odonne G, Herbette G, Eparvier V, Bourdy G, Rojas R, et al. (2011) Antileishmanial sesquiterpene lactones from Pseudelephantopus spicatus, a traditional remedy from the Chayahuita Amerindians (Peru) Part III. J Ethnopharmacol 137: 875-879.
    • (2011) J Ethnopharmacol , vol.137 , pp. 875-879
    • Odonne, G.1    Herbette, G.2    Eparvier, V.3    Bourdy, G.4    Rojas, R.5
  • 16
    • 53049090855 scopus 로고    scopus 로고
    • Leishmaniasis: drug resistance and natural products
    • Polonio T, Efferth T, (2008) Leishmaniasis: drug resistance and natural products. Int J Mol Med 22: 277-286.
    • (2008) Int J Mol Med , vol.22 , pp. 277-286
    • Polonio, T.1    Efferth, T.2
  • 17
    • 79953052697 scopus 로고    scopus 로고
    • Natural products and Chagas disease: a review of plant compounds studied for activity against Trypanosoma cruzi
    • Izumi E, Ueda-Nakamura T, Dias Filho BP, Veiga Junior VF, Nakamura CV, (2011) Natural products and Chagas disease: a review of plant compounds studied for activity against Trypanosoma cruzi. Nat Prod Rep 28: 809-823.
    • (2011) Nat Prod Rep , vol.28 , pp. 809-823
    • Izumi, E.1    Ueda-Nakamura, T.2    Dias Filho, B.P.3    Veiga Junior, V.F.4    Nakamura, C.V.5
  • 18
    • 84860676070 scopus 로고    scopus 로고
    • The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I
    • Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, et al. (2012) The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases- part I. Curr Med Chem 19: 2128-2175.
    • (2012) Curr Med Chem , vol.19 , pp. 2128-2175
    • Schmidt, T.J.1    Khalid, S.A.2    Romanha, A.J.3    Alves, T.M.4    Biavatti, M.W.5
  • 19
    • 79954624904 scopus 로고    scopus 로고
    • Antitrypanosomal agents from higher plants
    • In: Williams L, editor Kerala: Research Signpost
    • Setzer W, Setzer M (2006) Antitrypanosomal agents from higher plants. In: Williams L, editor. Biologically Active Natural Products for the 21st Century. Kerala: Research Signpost. pp. 47-95.
    • (2006) Biologically Active Natural Products for the 21st Century , pp. 47-95
    • Setzer, W.1    Setzer, M.2
  • 20
    • 46249091160 scopus 로고    scopus 로고
    • Trypanocidal and leishmanicidal activities of sesquiterpene lactones from Ambrosia tenuifolia Sprengel (Asteraceae)
    • Sülsen VP, Frank FM, Cazorla SI, Anesini CA, Malchiodi EL, et al. (2008) Trypanocidal and leishmanicidal activities of sesquiterpene lactones from Ambrosia tenuifolia Sprengel (Asteraceae). Antimicrob Agents Chemother 52: 2415-2419.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2415-2419
    • Sülsen, V.P.1    Frank, F.M.2    Cazorla, S.I.3    Anesini, C.A.4    Malchiodi, E.L.5
  • 21
    • 75749087595 scopus 로고    scopus 로고
    • Antiproliferative effect and ultrastructural alterations induced by psilostachyin on Trypanosoma cruzi
    • Sülsen VP, Barrera P, Muschietti L, Martino V, Sosa M, (2010) Antiproliferative effect and ultrastructural alterations induced by psilostachyin on Trypanosoma cruzi. Molecules 15: 515 545-553.
    • (2010) Molecules , vol.15 , pp. 545-553
    • Sülsen, V.P.1    Barrera, P.2    Muschietti, L.3    Martino, V.4    Sosa, M.5
  • 24
    • 0037369744 scopus 로고    scopus 로고
    • Trypanosoma cruzi infection modulates in vivo expression of major histocompatibility complex class II molecules on antigen-presenting cells and T-cell stimulatory activity of dendritic cells in a strain-dependent manner
    • Alba Soto CD, Mirkin GA, Solana ME, González Cappa SM, (2003) Trypanosoma cruzi infection modulates in vivo expression of major histocompatibility complex class II molecules on antigen-presenting cells and T-cell stimulatory activity of dendritic cells in a strain-dependent manner. Infect Immun 71: 1194-1199.
    • (2003) Infect Immun , vol.71 , pp. 1194-1199
    • Alba Soto, C.D.1    Mirkin, G.A.2    Solana, M.E.3    González Cappa, S.M.4
  • 25
    • 0344683235 scopus 로고    scopus 로고
    • National Research Council Eighth Edition.Washington DC: National Academy Press
    • National Research Council (2011) Guide for the care and use of laboratory animals. Eighth Edition.Washington DC: National Academy Press.
    • (2011) Guide for the care and use of laboratory animals
  • 26
    • 0029861640 scopus 로고    scopus 로고
    • Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing β- galactosidase
    • Buckner FS, Verlinde CL, La Flamme AA, Van Voorhis WC, (1996) Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing β- galactosidase. Antimicrob Agents Chemother 40: 2592-2597.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2592-2597
    • Buckner, F.S.1    Verlinde, C.L.2    La Flamme, A.A.3    Van Voorhis, W.C.4
  • 28
    • 0009481239 scopus 로고
    • Sesquiterpene lactones. Constituents of Ambrosia artemisiifolia L. (Compositae)
    • Porter T, Mabry T, (1969) Sesquiterpene lactones. Constituents of Ambrosia artemisiifolia L. (Compositae). Phytochemistry 8: 793-794.
    • (1969) Phytochemistry , vol.8 , pp. 793-794
    • Porter, T.1    Mabry, T.2
  • 29
    • 0040616004 scopus 로고
    • The structure of cumanin, a constituent of Ambrosia cumanensis
    • Romo J, Joseph-Nathan P, Siade G, (1966) The structure of cumanin, a constituent of Ambrosia cumanensis. Tetrahedron 22: 1499-1506.
    • (1966) Tetrahedron , vol.22 , pp. 1499-1506
    • Romo, J.1    Joseph-Nathan, P.2    Siade, G.3
  • 30
    • 84857655347 scopus 로고    scopus 로고
    • The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications
    • Zingales B, Miles MA, Campbell DA, Tibayrenc M, Macedo AM, et al. (2012) The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infect Genet Evol 12: 240-253.
    • (2012) Infect Genet Evol , vol.12 , pp. 240-253
    • Zingales, B.1    Miles, M.A.2    Campbell, D.A.3    Tibayrenc, M.4    Macedo, A.M.5
  • 31
    • 2942568100 scopus 로고    scopus 로고
    • Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages
    • Risso MG, Garbarino GB, Mocetti E, Campetella O, Gonzalez Cappa SM, et al. (2004) Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages. J Infect Dis 189 (12) (): 2250-2259.
    • (2004) J Infect Dis , vol.189 , Issue.12 , pp. 2250-2259
    • Risso, M.G.1    Garbarino, G.B.2    Mocetti, E.3    Campetella, O.4    Gonzalez Cappa, S.M.5
  • 34
    • 0028100860 scopus 로고
    • Cross reactivity studies and differential serodiagnosis of human infections caused by Trypanosoma cruzi and Leishmania spp: use of immunoblotting and ELISA with a purified antigen (Ag 163B6)
    • Malchiodi EL, Chiaramonte MG, Taranto NJ, Zwirner NW, Margni RA, (1994) Cross reactivity studies and differential serodiagnosis of human infections caused by Trypanosoma cruzi and Leishmania spp: use of immunoblotting and ELISA with a purified antigen (Ag 163B6). Clin Exp Immunol 97: 417-423.
    • (1994) Clin Exp Immunol , vol.97 , pp. 417-423
    • Malchiodi, E.L.1    Chiaramonte, M.G.2    Taranto, N.J.3    Zwirner, N.W.4    Margni, R.A.5
  • 36
    • 0032912333 scopus 로고    scopus 로고
    • Polymerase chain reaction reveals T. cruzi infection suspected by serology in cutaneous and mucocutaneous leishmaniasis patients
    • Chiaramonte MG, Frank FM, Furer GM, Taranto NJ, Margni RA, et al. (1999) Polymerase chain reaction reveals T. cruzi infection suspected by serology in cutaneous and mucocutaneous leishmaniasis patients. Acta Trop 72: 295-308.
    • (1999) Acta Trop , vol.72 , pp. 295-308
    • Chiaramonte, M.G.1    Frank, F.M.2    Furer, G.M.3    Taranto, N.J.4    Margni, R.A.5
  • 37
    • 77952076256 scopus 로고    scopus 로고
    • Cytotoxic and anti infective sesquiterpenes present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae)
    • Aponte JC, Yang H, Vaisberg AJ, Castillo D, Malaga E, et al. (2010) Cytotoxic and anti infective sesquiterpenes present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae). Planta Med 76: 705-707.
    • (2010) Planta Med , vol.76 , pp. 705-707
    • Aponte, J.C.1    Yang, H.2    Vaisberg, A.J.3    Castillo, D.4    Malaga, E.5
  • 38
    • 0036676714 scopus 로고    scopus 로고
    • Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones
    • Schmidt TJ, Brun R, Willuhn G, Khalid SA, (2002) Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones. Planta Med 68: 750-751.
    • (2002) Planta Med , vol.68 , pp. 750-751
    • Schmidt, T.J.1    Brun, R.2    Willuhn, G.3    Khalid, S.A.4
  • 39
    • 7044247321 scopus 로고    scopus 로고
    • The ambrosanolide cumanin inhibits macrophage nitric oxide synthesis: some structural considerations
    • Lastra AL, Ramírez TO, Salazar L, Martínez M, Trujillo-Ferrara J, (2004) The ambrosanolide cumanin inhibits macrophage nitric oxide synthesis: some structural considerations. J Ethnopharmacol 95: 221-227.
    • (2004) J Ethnopharmacol , vol.95 , pp. 221-227
    • Lastra, A.L.1    Ramírez, T.O.2    Salazar, L.3    Martínez, M.4    Trujillo-Ferrara, J.5
  • 40
    • 84865991815 scopus 로고    scopus 로고
    • Sesquiterpene lactones and the diterpene 5-epi-icetexone affect the intracellular and extracellular stages of Trypanosoma cruzi
    • Lozano E, Barrera P, Salinas R, Vega I, Nieto M, et al. (2012) Sesquiterpene lactones and the diterpene 5-epi-icetexone affect the intracellular and extracellular stages of Trypanosoma cruzi. Parasitol Int 61: 628-633.
    • (2012) Parasitol Int , vol.61 , pp. 628-633
    • Lozano, E.1    Barrera, P.2    Salinas, R.3    Vega, I.4    Nieto, M.5
  • 42
    • 38849099709 scopus 로고    scopus 로고
    • Trypanosoma cruzi: antiprotozoal activity of parthenolide obtained from Tanacetum parthenium (L.) Schultz Bip. (Asteraceae, Compositae) against epimastigote and amastigote forms
    • Izumi E, Morello LG, Ueda-Nakamura T, Yamada-Ogatta SF, Filho BP, et al. (2008) Trypanosoma cruzi: antiprotozoal activity of parthenolide obtained from Tanacetum parthenium (L.) Schultz Bip. (Asteraceae, Compositae) against epimastigote and amastigote forms. Exp Parasitol 118: 324-330.
    • (2008) Exp Parasitol , vol.118 , pp. 324-330
    • Izumi, E.1    Morello, L.G.2    Ueda-Nakamura, T.3    Yamada-Ogatta, S.F.4    Filho, B.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.