Increased mTORC1 activity contributes to atherosclerosis in apolipoprotein e knockout mice and in vascular smooth muscle cells

International Journal of Cardiology

Volumn 168, Issue 6, 2013, Pages 5450-5453

  Ma, Kun Ling ^a   Liu, Jing ^a   Wang, Chang Xian ^a   Ni, Jie ^a   Zhang, Yang ^a   Wu, Yu ^a   Lv, Lin Li ^a   Ruan, Xiong Zhong ^b   Liu, Bi Cheng ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Atherosclerosis; Inflammation; LDL receptor pathway; Mammalian target of rapamycin

Indexed keywords

APOLIPOPROTEIN E; INITIATION FACTOR 4E BINDING PROTEIN 1; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN; RETINOBLASTOMA BINDING PROTEIN; S6 KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ATHEROSCLEROSIS; CELL CYCLE S PHASE; CONTROLLED STUDY; DISEASE COURSE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME REGULATION; GENE TRANSLOCATION; INFLAMMATION; LETTER; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ATHEROSCLEROSIS; INFLAMMATION; LDL RECEPTOR PATHWAY; MAMMALIAN TARGET OF RAPAMYCIN;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; MICE; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; TOR SERINE-THREONINE KINASES;

EID: 84887185665     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.03.152     Document Type: Article

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