Ultra-high-performance liquid chromatography-tandem mass spectrometry measurement of climbazole deposition from hair care products onto artificial skin and human scalp

Journal of Chromatography A

Volumn 1317, Issue , 2013, Pages 155-158

  Chen, Guoqiang ^a,b   Hoptroff, Michael ^a   Fei, Xiaoqing ^a   Su, Ya ^a   Janssen, Hans Gerd ^b,c  

^a Unilever R and D   (China)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

Author keywords

Artificial skin; Climbazole; Deposition; Human scalp; MS MS; UHPLC

Indexed keywords

ARTIFICIAL SKIN; CLIMBAZOLE; HUMAN SCALP; MS/MS; UHPLC;

ATMOSPHERIC PRESSURE; CHEMICAL DETECTION; CHROMATOGRAPHY; DEPOSITION; DEUTERIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SOLVENT EXTRACTION;

ARTIFICIAL ORGANS;

ANTIFUNGAL AGENT; CLIMBAZOLE; DERMATOLOGICAL AGENT; DEUTERATED CLIMBAZOLE; HAIR CARE PRODUCT; PHOSPHATE BUFFERED SALINE; SURFACTANT; UNCLASSIFIED DRUG; IMIDAZOLE DERIVATIVE; METHANOL; SOAP;

ARTICLE; ARTIFICIAL SKIN; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; CHEMICAL PARAMETERS; CHEMICAL REACTION; CONTROLLED STUDY; DRUG DEPOSITION; DRUG STRUCTURE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; NORMAL HUMAN; PERFORMANCE; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; SAMPLING; SCALP; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY; BIOLOGICAL MODEL; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; PHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; SKIN ABSORPTION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; IMIDAZOLES; MALE; METHANOL; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; SCALP; SKIN ABSORPTION; SKIN, ARTIFICIAL; SOAPS; TANDEM MASS SPECTROMETRY;

EID: 84887163780     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.08.032     Document Type: Article

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