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Volumn 27, Issue 12, 2013, Pages 1767-1774

Identification of the metabolites of anti-inflammatory compound clematichinenoside AR in rat intestinal microflora

Author keywords

Clematichinenoside AR; Intestinal microflora; LC Q TOF MS; Metabolite identification

Indexed keywords

BIOMOLECULES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINE; RATS;

EID: 84887135193     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2991     Document Type: Article
Times cited : (13)

References (15)
  • 1
    • 0032421318 scopus 로고    scopus 로고
    • Antimetastatic efficacy of orally administered ginsenoside Rb1 in dependence on intestinal bacterial hydrolyzing potential and significance of treatment with an active bacterial metabolite
    • Hasegawa H and Uchiyama M. Antimetastatic efficacy of orally administered ginsenoside Rb1 in dependence on intestinal bacterial hydrolyzing potential and significance of treatment with an active bacterial metabolite. Planta Medica 1998; 64: 696-700.
    • (1998) Planta Medica , vol.64 , pp. 696-700
    • Hasegawa, H.1    Uchiyama, M.2
  • 2
    • 34447552680 scopus 로고    scopus 로고
    • Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats
    • He JX, Goto E, Akao T and Tani T. Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats. Phytomedicine 2007; 14: 452-459.
    • (2007) Phytomedicine , vol.14 , pp. 452-459
    • He, J.X.1    Goto, E.2    Akao, T.3    Tani, T.4
  • 3
    • 53149089114 scopus 로고    scopus 로고
    • Biotransformation of ginsenoside Rb1, crocin, amygdalin, geniposide, puerarin, ginsenoside Re, hesperidin, poncirin, glycyrrhizin, and baicalin by human fecal microflora and its relation to cytotoxicity against tumor cells
    • Kim YS, Kim JJ, Cho KH, Jung WS, Moon SK, Park EK and Kim DH. Biotransformation of ginsenoside Rb1, crocin, amygdalin, geniposide, puerarin, ginsenoside Re, hesperidin, poncirin, glycyrrhizin, and baicalin by human fecal microflora and its relation to cytotoxicity against tumor cells. Journal of Microbiology and Biotechnology 2008; 18: 1109-1114.
    • (2008) Journal of Microbiology and Biotechnology , vol.18 , pp. 1109-1114
    • Kim, Y.S.1    Kim, J.J.2    Cho, K.H.3    Jung, W.S.4    Moon, S.K.5    Park, E.K.6    Kim, D.H.7
  • 7
    • 78049257884 scopus 로고    scopus 로고
    • Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract
    • Lu XY, Sun DL, Chen ZJ, Chen T, Li LP, Xu ZH, Jiang HD and Zeng S. Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract. Journal of Agriculture and Food Chemistry 2010; 58: 10661-10667.
    • (2010) Journal of Agriculture and Food Chemistry , vol.58 , pp. 10661-10667
    • Lu, X.Y.1    Sun, D.L.2    Chen, Z.J.3    Chen, T.4    Li, L.P.5    Xu, Z.H.6    Jiang, H.D.7    Zeng, S.8
  • 8
  • 9
    • 0020530970 scopus 로고
    • Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. III. The absorption, distribution and excretion of ginsenoside Rb1 in the rat
    • Odani T, Tanizawa H and Takino Y. Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. III. The absorption, distribution and excretion of ginsenoside Rb1 in the rat. Chemical & Pharmaceutical Bulletin (Tokyo) 1983; 31: 1059-1066.
    • (1983) Chemical & Pharmaceutical Bulletin (Tokyo) , vol.31 , pp. 1059-1066
    • Odani, T.1    Tanizawa, H.2    Takino, Y.3
  • 10
    • 84867855784 scopus 로고    scopus 로고
    • Anti-inflammatory effects of Clematis chinensis Osbeck extract(AR-6) may be associated with NF-kappaB, TNF-alpha, and COX-2 in collagen-induced arthritis in rat
    • Peng C, Perera PK, Li YM, Fang WR, Liu LF and Li FW. Anti-inflammatory effects of Clematis chinensis Osbeck extract(AR-6) may be associated with NF-kappaB, TNF-alpha, and COX-2 in collagen-induced arthritis in rat. Rheumatology International 2011; 32: 3119-3125.
    • (2011) Rheumatology International , vol.32 , pp. 3119-3125
    • Peng, C.1    Perera, P.K.2    Li, Y.M.3    Fang, W.R.4    Liu, L.F.5    Li, F.W.6
  • 13
    • 84887204733 scopus 로고    scopus 로고
    • The State Pharmacopoeia Committee of P. R. China. China Medical Science Press: Beijing
    • The State Pharmacopoeia Committee of P. R. China. Chinese Pharmacopoeia, Vol. 1. China Medical Science Press: Beijing, 2010; 234-235 .
    • (2010) Chinese Pharmacopoeia, Vol. 1 , pp. 234-235
  • 14
    • 84865754719 scopus 로고    scopus 로고
    • Validated LC-MS/MS assay for the quantitative determination of clematichinenoside AR in rat plasma and its application to a pharmacokinetic study
    • Wang D, Li F, Li P, Zhang J, Liu L, Xu P, Zhou L and Liu X. Validated LC-MS/MS assay for the quantitative determination of clematichinenoside AR in rat plasma and its application to a pharmacokinetic study. Biomedical Chromatography 2012; 26: 1282-1285.
    • (2012) Biomedical Chromatography , vol.26 , pp. 1282-1285
    • Wang, D.1    Li, F.2    Li, P.3    Zhang, J.4    Liu, L.5    Xu, P.6    Zhou, L.7    Liu, X.8
  • 15
    • 77449089475 scopus 로고    scopus 로고
    • Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies
    • Yu Y, Liu L, Wang X, Liu X, Xie L and Wang G. Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies. Biochemical Pharmacology 2010; 79: 1000-1006.
    • (2010) Biochemical Pharmacology , vol.79 , pp. 1000-1006
    • Yu, Y.1    Liu, L.2    Wang, X.3    Liu, X.4    Xie, L.5    Wang, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.