Absence of a robust innate immune response in rat neurons facilitates persistent infection of Borna disease virus in neuronal tissue

Cellular and Molecular Life Sciences

Volumn 70, Issue 22, 2013, Pages 4399-4410

  Lin, Chia Ching ^a   Wu, Yuan Ju ^a   Heimrich, Bernd ^a   Schwemmle, Martin ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Hippocampus; Innate immunity; Neurotropic viruses; Viral persistence

Indexed keywords

ALPHA INTERFERON; MYXOVIRUS RESISTANCE PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BORNA DISEASE VIRUS; BRAIN SLICE; CELL NUCLEUS; CELL TYPE; CONTROLLED STUDY; CYTOKINE RELEASE; FACILITATION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; INFECTION SENSITIVITY; INNATE IMMUNITY; MICROGLIA; MOUSE; NERVE CELL; NERVOUS TISSUE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PERSISTENT VIRUS INFECTION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; RNA VIRUS INFECTION; TISSUE CULTURE; UPREGULATION; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS TRANSMISSION; ANIMAL; BAGG ALBINO MOUSE; BORNA DISEASE; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; HIPPOCAMPUS; IMMUNOLOGY; LEWIS RAT; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VIROLOGY;

BORNA DISEASE VIRUS; MUS; RATTUS;

ANIMALS; ASTROCYTES; BORNA DISEASE; BORNA DISEASE VIRUS; HIPPOCAMPUS; IMMUNITY, INNATE; INTERFERON-ALPHA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROGLIA; MYXOVIRUS RESISTANCE PROTEINS; NEURONS; PHOSPHORYLATION; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; UP-REGULATION; VIRUS REPLICATION;

EID: 84887125513     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1402-5     Document Type: Article

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