Urban air pollutants reduce synaptic function of CA1 neurons via an NMDA/NÈ® pathway in vitro

Journal of Neurochemistry

Volumn 127, Issue 4, 2013, Pages 509-519

  Davis, David A ^a   Akopian, Garnik ^a   Walsh, John P ^a   Sioutas, Constantinos ^b   Morgan, Todd E ^a   Finch, Caleb E ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE   (United States)

Author keywords

air pollution; CA1 neurons; glutamate; nitric oxide; nitrosylation; NMDA

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AMPA SUBUNIT 1; GLUTAMATE RECEPTOR AMPA SUBUNIT 2; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITRIC OXIDE; POSTSYNAPTIC DENSITY PROTEIN 95; SPINOPHILIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

AIR POLLUTANT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN SLICE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DENTATE GYRUS; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPAL CA1 REGION; IMMUNOCHEMISTRY; IN VITRO STUDY; LONG TERM EXPOSURE; MALE; MOUSE; NITROSYLATION; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; URBAN AREA;

RODENTIA;

EID: 84887093222     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12395     Document Type: Article

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