Golimumab, a human anti-tumor necrosis factor monoclonal antibody, injected subcutaneously every 4 weeks in patients with active rheumatoid arthritis who had never taken methotrexate: 1-year and 2-year clinical, radiologic, and physical function findings of a phase III, multicenter, randomized, double-blind, placebo-controlled study

Arthritis Care and Research

Volumn 65, Issue 11, 2013, Pages 1732-1742

  Emery, Paul ^a   Fleischmann, Roy M ^b   Doyle, Mittie K ^c   Strusberg, Ingrid ^d   Durez, Patrick ^e   Nash, Peter ^f,l   Amante, Eric ^g   Churchill, Melvin ^h   Park, Won ⁱ   Pons Estel, Bernardo ^j   Xu, Weichun ^c   Xu, Stephen ^c,l   Wu, Zhong ^c   Hsia, Elizabeth C ^k  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d Instituto Reumatológico Strusberg   (Argentina)

^e CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g UNIVERSITY OF THE PHILIPPINES MANILA   (Philippines)

^h Arthritis Center of Nebraska   (United States)

ⁱ Inha University Hospital   (South Korea)

^j Sanatorio Parque   (Argentina)

^k UNIVERSITY OF PENNSYLVANIA   (United States)

^l ALEXION PHARMACEUTICALS   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GOLIMUMAB; METHOTREXATE; PLACEBO;

ADULT; ADVERSE OUTCOME; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BRONCHITIS; CONTROLLED STUDY; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEALTH ASSESSMENT QUESTIONNAIRE; HUMAN; INJECTION SITE ERYTHEMA; INJECTION SITE REACTION; JOINT RADIOGRAPHY; JOINT SWELLING; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; SERUM SICKNESS; SIDE EFFECT; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, SUBCUTANEOUS; MALE; METHOTREXATE; MIDDLE AGED; MOTOR ACTIVITY; TIME FACTORS; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84887089482     PISSN: 2151464X     EISSN: 21514658     Source Type: Journal    
DOI: 10.1002/acr.22072     Document Type: Article

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