Antibody-dependent enhancement of PRRSV infection down-modulates TNF-α and IFN-β transcription in macrophages

Veterinary Immunology and Immunopathology

Volumn 156, Issue 1-2, 2013, Pages 128-134

  Bao, Dengke ^a,b   Wang, Rui ^b   Qiao, Songlin ^b   Wan, Bo ^a,b   Wang, Yinbiao ^a,b   Liu, Mingyang ^b   Shi, Xibao ^b   Guo, Juiqing ^b   Zhang, Gaiping ^a,b  

^a JILIN UNIVERSITY   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Antibody dependent enhancement (ADE); Down modulate; Fc RIIb; Interferon; Porcine reproductive and respiratory syndrome virus (PRRSV)

Indexed keywords

BETA INTERFERON; FC RECEPTOR IIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ANTIBODY DEPENDENT ENHANCEMENT; ANTIGEN ANTIBODY COMPLEX; ANTIVIRAL ACTIVITY; ARTERIVIRUS; ARTICLE; IMMUNE RESPONSE; MACROPHAGE; MOLECULAR MECHANICS; NONHUMAN; PATHOGENESIS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; VIRUS REPLICATION;

PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SUIDAE; SUS;

ANTIBODY-DEPENDENT ENHANCEMENT (ADE); DOWN-MODULATE; FCΓRIIB; INTERFERON; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV);

ANIMALS; ANTIBODY-DEPENDENT ENHANCEMENT; DOWN-REGULATION; INTERFERON-BETA; MACROPHAGES; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; SWINE; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84887083206     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2013.09.006     Document Type: Article

References (25)

1. Cancel-Tirado S.M., Evans R.B., Yoon K.J. Monoclonal antibody analysis of porcine reproductive and respiratory syndrome virus epitopes associated with antibody-dependent enhancement and neutralization of virus infection. Vet. Immunol. Immunopathol. 2004, 102:249-262.
2. Christianson W.T., Choi C.S., Collins J.E., Molitor T.W., Morrison R.B., Joo H.S. Pathogenesis of porcine reproductive and respiratory syndrome virus infection in mid-gestation sows and fetuses. Can. J. Vet. Res. 1993, 57:262-268.
3. Collins J.E., Benfield D.A., Christianson W.T., Harris L., Hennings J.C., Shaw D.P., Goyal S.M., McCullough S., Morrison R.B., Joo H.S.et al. Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs. J. Vet. Diagn. Invest. 1992, 4:117-126.
4. Duan X., Nauwynck H.J., Pensaert M.B. Virus quantification and identification of cellular targets in the lungs and lymphoid tissues of pigs at different time intervals after inoculation with porcine reproductive and respiratory syndrome virus (PRRSV). Vet. Microbiol. 1997, 56:9-19.
5. Halstead S.B., O'Rourke E.J. Antibody-enhanced dengue virus infection in primate leukocytes. Nature 1977, 265:739-741.
6. Halstead S.B., Mahalingam S., Marovich M.A., Ubol S., Mosser D.M. Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes. Lancet Infect. Dis. 2010, 10:712-722.
7. Karniychuk U.U., Saha D., Vanhee M., Geldhof M., Cornillie P., Caij A.B., De Regge N., Nauwynck H.J. Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge. Theriogenology 2012, 78:1527-1537.
8. Lee S.M., Kleiboeker S.B. Porcine arterivirus activates the NF-kappaB pathway through IkappaB degradation. Virology 2005, 342:47-59.
9. Lidbury B.A., Mahalingam S. Specific ablation of antiviral gene expression in macrophages by antibody-dependent enhancement of Ross River virus infection. J. Virol. 2000, 74:8376-8381.
10. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
11. Mahalingam S., Lidbury B.A. Suppression of lipopolysaccharide-induced antiviral transcription factor (STAT-1 and NF-kappa B) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:13819-13824.
12. Meulenberg J.J., Hulst M.M., de Meijer E.J., Moonen P.L., den Besten A., de Kluyver E.P., Wensvoort G., Moormann R.J. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology 1993, 192:62-72.
13. Meyer K., Ait-Goughoulte M., Keck Z.Y., Foung S., Ray R. Antibody-dependent enhancement of hepatitis C virus infection. J. Virol. 2008, 82:2140-2149.
14. Murtaugh M.P., Xiao Z., Zuckermann F. Immunological responses of swine to porcine reproductive and respiratory syndrome virus infection. Viral Immunol. 2002, 15:533-547.
15. Qiao S., Zhang G., Xia C., Zhang H., Zhang Y., Xi J., Song H., Li X. Cloning and characterization of porcine Fc gamma receptor II (FcgammaRII). Vet. Immunol. Immunopathol. 2006, 114:178-184.
16. Qiao S., Feng L., Bao D., Guo J., Wan B., Xiao Z., Yang S., Zhang G. Porcine reproductive and respiratory syndrome virus and bacterial endotoxin act in synergy to amplify the inflammatory response of infected macrophages. Vet. Microbiol. 2011, 149:8.
17. Qiao S., Jiang Z., Tian X., Wang R., Xing G., Wan B., Bao D., Liu Y., Hao H., Guo J., Zhang G. Porcine FcgammaRIIb mediates enhancement of porcine reproductive and respiratory syndrome virus (PRRSV) infection. PLoS ONE 2011, 6:e28721.
18. Shibata I., Mori M., Uruno K. Experimental infection of maternally immune pigs with porcine reproductive and respiratory syndrome (PRRS) virus. J. Vet. Med. Sci. 1998, 60:1285-1291.
19. Tirado S.M., Yoon K.J. Antibody-dependent enhancement of virus infection and disease. Viral Immunol. 2003, 16:69-86.
20. Ubol S., Halstead S.B. How innate immune mechanisms contribute to antibody-enhanced viral infections. Clin. Vaccine Immunol. 2010, 17:1829-1835.
21. Ubol S., Phuklia W., Kalayanarooj S., Modhiran N. Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies. J. Infect. Dis. 2010, 201:923-935.
22. Wensvoort G., Terpstra C., Pol J.M., ter Laak E.A., Bloemraad M., de Kluyver E.P., Kragten C., van Buiten L., den Besten A., Wagenaar F., et al. Mystery swine disease in The Netherlands: the isolation of Lelystad virus. Vet. Q. 1991, 13:121-130.
23. Yoon K.J., Wu L.L., Zimmerman J.J., Hill H.T., Platt K.B. Antibody-dependent enhancement (ADE) of porcine reproductive and respiratory syndrome virus (PRRSV) infection in pigs. Viral Immunol. 1996, 9:51-63.
24. Yoon K.J., Wu L.L., Zimmerman J.J., Platt K.B. Field isolates of porcine reproductive and respiratory syndrome virus (PRRSV) vary in their susceptibility to antibody dependent enhancement (ADE) of infection. Vet. Microbiol. 1997, 55:277-287.
25. Zhang Y., Zhou Y., Yang Q., Mu C., Duan E., Chen J., Yang M., Xia P., Cui B. Ligation of Fc gamma receptor IIB enhances levels of antiviral cytokine in response to PRRSV infection in vitro. Vet. Microbiol. 2012, (in press).