Cooperation of endothelial and smooth muscle cells derived from human induced pluripotent stem cells enhances neovascularization in dermal wounds

Tissue Engineering - Part A

Volumn 19, Issue 21-22, 2013, Pages 2478-2485

  Kim, Koung Li ^a   Song, Sun Hwa ^a   Choi, Kyu Sil ^b   Suh, Wonhee ^a  

^a Ajou University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL CELLS; STEM CELLS; TISSUE REGENERATION;

AUTOLOGOUS CELL SOURCE; CO-IMPLANTATION; DIFFERENTIATED CELLS; HUMAN-INDUCED PLURIPOTENT STEM CELLS; NEO-VASCULARIZATION; PHOSPHATE-BUFFERED SALINES; SMOOTH MUSCLE CELLS; TUBULAR NETWORKS;

CYTOLOGY;

CYTOKINE; GROWTH FACTOR; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL CULTURE; CELL DIFFERENTIATION; CELL THERAPY; CONFERENCE PAPER; CONTROLLED STUDY; DERMIS; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NUDE MOUSE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; TISSUE INJURY; TISSUE REPAIR; VASCULAR DISEASE; VASCULARIZATION; WOUND; WOUND HEALING;

MURINAE; MUS MUSCULUS;

ANIMALS; ENDOTHELIAL CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, NUDE; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; SKIN; TISSUE ENGINEERING;

EID: 84887072804     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0768     Document Type: Conference Paper

References (15)

1. Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861, 2007
2. Park, S.W., Jun Koh, Y., Jeon, J., Cho, Y.H., Jang, M.J., Kang, Y., et al. Efficient differentiation of human pluripotent stem cells into functional CD34 + progenitor cells by combined modulation of the MEK/ERK and BMP4 signaling pathways. Blood 116, 5762, 2010
3. Rufaihah, A.J., Huang, N.F., Jame, S., Lee, J.C., Nguyen, H.N., Byers, B., et al. Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol 31, e72, 2011
4. Harder, Y., Amon, M., Erni, D., and Menger, M.D. Evolution of ischemic tissue injury in a random pattern flap: A new mouse model using intravital microscopy. J Surg Res 121, 197, 2004
5. Straino, S., Germani, A., Di Carlo, A., Porcelli, D., De Mori, R., Mangoni, A., et al. Enhanced arteriogenesis and wound repair in dystrophin-deficient mdx mice. Circulation 110, 3341, 2004
6. Kim, J.Y., Song, S.H., Kim, K.L., Ko, J.J., Im, J.E., Yie, S.W., et al. Human cord blood-derived endothelial progenitor cells and their conditioned media exhibit therapeutic equivalence for diabetic wound healing. Cell Transplant 19, 1635, 2010
7. Lee, T.H., Song, S.H., Kim, K.L., Yi, J.Y., Shin, G.H., Kim, J.Y., et al. Functional recapitulation of smooth muscle cells via induced pluripotent stem cells from human aortic smooth muscle cells. Circ Res 106, 120, 2010
8. van Cruijsen, H., Giaccone, G., and Hoekman, K. Epidermal growth factor receptor and angiogenesis: Opportunities for combined anticancer strategies. Int J Cancer 117, 883, 2005
9. Jazwa, A., Kucharzewska, P., Leja, J., Zagorska, A., Sierpniowska, A., Stepniewski, J., et al. Combined vascular endothelial growth factor-A and fibroblast growth factor 4 gene transfer improves wound healing in diabetic mice. Genet Vaccines Ther 8, 6, 2010
10. Poling, J., Szibor, M., Schimanski, S., Ingelmann, M.E., Rees, W., Gajawada, P., et al. Induction of smooth muscle cell migration during arteriogenesis is mediated by Rap2. Arterioscler Thromb Vasc Biol 31, 2297, 2011
11. Melero-Martin, J.M., Khan, Z.A., Picard, A., Wu, X., Paruchuri, S., and Bischoff, J. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 109, 4761, 2007
12. Foubert, P., Matrone, G., Souttou, B., Lere-Dean, C., Barateau, V., Plouet, J., et al. Coadministration of endothelial and smooth muscle progenitor cells enhances the efficiency of proangiogenic cell-based therapy. Circ Res 103, 751, 2008
13. Melero-Martin, J.M., De Obaldia, M.E., Kang, S.Y., Khan, Z.A., Yuan, L., Oettgen, P., et al. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res 103, 194, 2008
14. Traktuev, D.O., Prater, D.N., Merfeld-Clauss, S., Sanjeevaiah, A.R., Saadatzadeh, M.R., Murphy, M., et al. Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells. Circ Res 104, 1410, 2009
15. Zhao, T., Zhang, Z.N., Rong, Z., and Xu, Y. Immunogenicity of induced pluripotent stem cells. Nature 474, 212, 2011