A plea to reduce or replace fetal bovine serum in cell culture media

Cytotechnology

Volumn 65, Issue 5, 2013, Pages 791-793

  Gstraunthaler, Gerhard ^a   Lindl, Toni ^b   Van Der Valk, Jan ^c  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b Institut für Angewandte Zellkultur   (Germany)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CELL PROTEIN; ENDOTOXIN; PRION PROTEIN; STABLE ISOTOPE; TISSUE CULTURE MEDIUM;

BEEF; BIOSAFETY; CATTLE FARMING; CELL ADHESION; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; COW; CULTURE MEDIUM; CYTOLOGY; DAIRY PRODUCT; DROUGHT; ENVIRONMENTAL FACTOR; FETAL BOVINE SERUM; FETUS; FOOT AND MOUTH DISEASE; HERD; HUMAN; LETTER; METABOLOMICS; MYCOPLASMA; NONHUMAN; PLURIPOTENT STEM CELL; SERUM; TISSUE CULTURE; VACCINE PRODUCTION;

BOVINAE;

EID: 84887062423     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-013-9633-8     Document Type: Letter

References (22)

1. Anderson NL, Anderson NG (2002) The human plasma proteome. History, character, and diagnostic prospects. Mol Cell Proteomics 1:845-867
2. Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, Conrads TP, Veenstra TD, Adkins JN, Pounds JG, Fagan R, Lobley A (2004) The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol Cell Proteomics 3:311-326 (Pubitemid 38702086)
3. Asher DM (1999) Bovine sera used in the manufacture of biologicals: current concerns and policies of the US Food and Drug Administration regarding the transmissible spongiform encephalopathies. Dev Biol Stand 99:41-44
4. Bohn B (1995) Fatal bovine serum. Nat Biotechnol 13:926-927
5. Brunner D, Frank J, Appl H, Schöffl H, Pfaller W, Gstraunthaler G (2010) Serum-free cell culture: the serum-free media interactive online database. ALTEX 27:53-62
6. Dormont D (1999) Transmissible spongiform encephalopathy agents and animal sera. Dev Biol Stand 99:25-34
7. Even MS, Sandusky CB, Barnard ND (2006) Serum-free hybridoma culture: ethical, scientific and safety considerations. Trends Biotechnol 24:105-108
8. FDA (2013) US Food and Drug Administration; http://www.accessdata.fda. gov/scripts/cdrh/cfdocs/cfRes/res.cfm?ID=117863
9. Fujimoto B (2002) Fetal bovine serum - supply vs. demand? Art Sci 21:1-4
10. Gstraunthaler G (2003) Alternatives to the use of fetal bovine serum: serum-free cell culture. ALTEX 20:275-281
11. Gstraunthaler G, Lindl T (2013) Zell- und Gewebekultur, 7th edn. Spektrum Springer Verlag, Heidelberg
12. Hodgson J (1991) Checking the sources: the serum supply secret. Nat Biotechnol 9:1320-1324
13. Hodgson J (1993) Fetal bovine serum revisited. Nat Biotechnol 11:49-53
14. Hodgson J (1995) To treat or not to treat: that is the question for serum. Nat Biotechnol 13:333-343
15. Jochems CE, van der Valk JBF, Stafleu FR, Baumans V (2002) The use of fetal bovine serum: ethical and scientific problem? ATLA 30:219-227 (Pubitemid 34534624)
16. Nielsen O (1995) Changing serum's mind-set. Nat Biotechnol 13:626
17. Psychogios N, Hau DD, Peng J, Guo AC, Mandal R, Bouatra S, Sinelnikov I, Krishnamurthy R, Eisner R, Gautam B, Young N, Xia J, Knox C, Dong E, Huang P, Hollander Z, Pedersen TL, Smith SR, Bamforth F, Greiner R, McManus B, Newman JW, Goodfriend T, Wishart DS (2011) The human serum metabolome. PLoS ONE 6:e16957
18. Rauch C, Feifel E, Amann E-M, Spötl HP, Schennach H, Pfaller W, Gstraunthaler G (2011) Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media. ALTEX 28:305-316
19. Shailer C, Corrin K (1999) Serum supply: policies and controls operating in New Zealand. Dev Biol Stand 99:71-77
20. van der Valk J, Mellor D, Brands R, Fischer R, Gruber F, Gstraunthaler G, Hellebrekers L, Hyllner J, Jonker FH, Prieto P, Thalen M, Baumans V (2004) The humane collection of fetal bovine serum and possibilities for serum-free cell and tissue culture. Toxicol In Vitro 18:1-12 (Pubitemid 37431045)
21. van der Valk J, Brunner D, De Smet K, Fex Svenningsen Å, Honegger P, Knudsen LE, Lindl T, Noraberg J, Price A, Scarino ML, Gstraunthaler G (2010) Optimization of chemically defined cell culture media - replacing fetal bovine serum in mammalian in vitro methods. Toxicol In Vitro 24:1053-1063
22. Wessmann SJ, Levings RL (1999) Benefits and risks due to animal serum used in cell culture production. Dev Biol Stand 99:3-8