Highly efficient targeted mutagenesis in mice using TALENs

Genetics

Volumn 195, Issue 3, 2013, Pages 703-713

  Panda, Sudeepta Kumar ^a,b   Wefers, Benedikt ^a   Ortiz, Oskar ^a   Floss, Thomas ^a   Schmid, Bettina ^c,d   Haass, Christian ^c,d   Wurst, Wolfgang ^a,b,c,e   Kühn, Ralf ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; NUCLEASE; OLIGODEOXYNUCLEOTIDE; POLYADENYLIC ACID; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG;

ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CODON; CONTROLLED STUDY; EMBRYO; FRAMESHIFT MUTATION; FRONTOTEMPORAL DEMENTIA; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENETIC ANALYSIS; GENETIC ENGINEERING; GENOME; GENOTYPE; HIGH RESOLUTION MELTING ANALYSIS; MISSENSE MUTATION; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

C9ORF72; DISEASE MODEL; FUS; MOUSE MUTANT; NUCLEASE; ONE-CELL EMBRYO; TALENS;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BASE SEQUENCE; DEOXYRIBONUCLEASES; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PREGNANCY; RNA, MESSENGER; RNA-BINDING PROTEIN FUS; TRANSCRIPTIONAL ACTIVATION;

EID: 84887061001     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.113.156570     Document Type: Article

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