Point-of-care and over-thecounter qualitative human chorionic gonadotropin (hcg) devices remain susceptible to false-negative results caused by excess HCG β core fragment

Clinical Chemistry

Volumn 59, Issue 11, 2013, Pages 1672-1674

  Nerenz, Robert D ^a   Gronowski, Ann M ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; CHORIONIC GONADOTROPIN; DIAGNOSTIC KIT;

FALSE NEGATIVE RESULT; GYNECOLOGICAL AND OBSTETRIC GENERAL EQUIPMENT; HUMAN; LETTER; OVER THE COUNTER DEVICE; POINT OF CARE DEVICE; POINT OF CARE TESTING; PREGNANCY RAPID TEST; PREGNANCY TEST; PRENATAL CARE; URINALYSIS; DEVICES; DIAGNOSTIC KIT; FEMALE; HOSPITAL INFORMATION SYSTEM; LABORATORY DIAGNOSIS; STANDARDS; URINE; EQUIPMENT; STANDARD;

CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FALSE NEGATIVE REACTIONS; FEMALE; HUMANS; POINT-OF-CARE SYSTEMS; PREGNANCY TESTS; REAGENT KITS, DIAGNOSTIC;

EID: 84887057082     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2013.212795     Document Type: Letter

References (4)

1. Gronowski AM, Cervinski M, Stenman UH, Woodworth A, Ashby L, Scott MG. False-negative results in point-of-care qualitative human chorionic gonadotropin (hCG) devices due to excess hCG- core fragment. Clin Chem 2009;55:1389-94.
2. Gronowski AM, Powers M, Stenman UH, Ashby L, Scott MG. False-negative results from pointof- care qualitative human chorionic gonadotropin (hCG) devices caused by excess hCG- core fragment vary with device lot number. Clin Chem 2009;55:1885- 6.
3. Butler SA, Khanlian SA, Cole LA. Detection of early pregnancy forms of human chorionic gonadotropin by home pregnancy test devices. Clin Chem 2001;47:2131- 6. (Pubitemid 33108877)
4. Sigel CS, Grenache DG. Detection of unexpected isoforms of human chorionic gonadotropin by qualitative tests. Clin Chem 2007; 53:989 -90. (Pubitemid 46744260)