Seeking for a way to revive erythropoietin production in chronic kidney disease

Journal of the Formosan Medical Association

Volumn 112, Issue 11, 2013, Pages 657-658

  Chang, Yu Ting ^a   Pan, Szu Yu ^b   Lin, Shuei Liong ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANEMIC AGENT; ERYTHROPOIETIN; FG 2216; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG;

ANEMIA; BLOOD LEVEL; CHRONIC KIDNEY DISEASE; ERYTHROPOIESIS; HEMATOCRIT; HEMODIALYSIS; HUMAN; INFLAMMATORY CELL; KIDNEY FIBROSIS; NONHUMAN; PERICYTE; RENAL ANEMIA; SHORT SURVEY;

ANEMIA; ANIMALS; DNA; ERYTHROPOIESIS; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; HUMANS; RENAL INSUFFICIENCY, CHRONIC;

EID: 84887022315     PISSN: None     EISSN: 09296646     Source Type: Journal    
DOI: 10.1016/j.jfma.2013.04.005     Document Type: Short Survey

References (8)

1. Chang F.C., Chou Y.H., Chen Y.T., Lin S.L. Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis. J Formos Med Assoc 2012, 111:589-598.
2. Pan S.Y., Chang Y.T., Lin S.L. The role of hypoxia-inducible factors in renal fibrosis. J Formos Med Assoc 2013, 112:587-588.
3. Solomon S.D., Uno H., Lewis E.F., Eckardt K.U., Lin J., Burdmann E.A., et al. Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med 2010, 363:1146-1155.
4. Bernhardt W.M., Wiesener M.S., Scigalla P., Chou J., Schmieder R.E., Gunzler V., et al. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. J Am Soc Nephrol 2010, 21:2151-2156.
5. Wenger R.H., Kvietikova I., Rolfs A., Camenisch G., Gassmann M. Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur J Biochem 1998, 253:771-777.
6. Yin H., Blanchard K.L. DNA methylation represses the expression of the human erythropoietin gene by two different mechanisms. Blood 2000, 95:111-119.
7. Steinmann K., Richter A.M., Dammann R.H. Epigenetic silencing of erythropoietin in human cancers. Genes Cancer 2011, 2:65-73.
8. Bechtel W., McGoohan S., Zeisberg E.M., Müller G.A., Kalbacher H., Salant D.J., et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med 2010, 16:544-550.