메뉴 건너뛰기




Volumn 98, Issue 11, 2013, Pages 1732-1738

Lenalidomide plus cyclophosphamide, doxorubicin, vincristine, prednisone and rituximab is safe and effective in untreated, elderly patients with diffuse large B-cell lymphoma: A phase I study by the Fondazione Italiana Linfomi

(20)  Chiappella, Annalisa a   Tucci, Alessandra b   Castellino, Alessia a   Pavone, Vincenzo c   Baldi, Ileana d   Carella, Angelo Michele e   Orsucci, Lorella a   Zanni, Manuela f   Salvi, Flavia g   Liberati, Anna Marina h   Gaidano, Gianluca i   Bottelli, Chiara b   Rossini, Bernardo c   Perticone, Sonia j   De Masi, Pasqualina a   Ladetto, Marco f   Ciccone, Giovannino k   Palumbo, Antonio f   Rossi, Giuseppe b   Vitolo, Umberto a  


Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; DOXORUBICIN; LAMIVUDINE; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; METHOTREXATE; PENTAMIDINE; PREDNISONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RITUXIMAB; VINCRISTINE;

EID: 84887011781     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2013.085134     Document Type: Article
Times cited : (51)

References (40)
  • 1
    • 78649391451 scopus 로고    scopus 로고
    • Improving outcomes for patients with diffuse large Bcell lymphoma
    • Flowers CR, Sinha R, Vose JM. Improving outcomes for patients with diffuse large Bcell lymphoma. CA Cancer J Clin. 2010; 60(16): 393-408.
    • (2010) CA Cancer J Clin , vol.60 , Issue.16 , pp. 393-408
    • Flowers, C.R.1    Sinha, R.2    Vose, J.M.3
  • 2
    • 77957200763 scopus 로고    scopus 로고
    • Long-term outcome of patients in the LNH-98. 5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: A study by the Groupe d'Etudes des Lymphomes de l'Adulte
    • Coiffier B, Thieblemont C, Van Den Neste E, Lepeu G, Plantier I, Castaigne S, et al. Long-term outcome of patients in the LNH-98. 5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d'Etudes des Lymphomes de l'Adulte. Blood. 2010; 116(12): 2040-5.
    • (2010) Blood , vol.116 , Issue.12 , pp. 2040-2045
    • Coiffier, B.1    Thieblemont, C.2    Van Den Neste, E.3    Lepeu, G.4    Plantier, I.5    Castaigne, S.6
  • 3
    • 38549147027 scopus 로고    scopus 로고
    • Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: A randomised controlled trial (RICOVER-60)
    • Pfreundschuh M, Schubert J, Ziepert M, Schmits R, Mohren M, Lengfelder E, et al. Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60). Lancet Oncol. 2008; 9(2): 105-16.
    • (2008) Lancet Oncol , vol.9 , Issue.2 , pp. 105-116
    • Pfreundschuh, M.1    Schubert, J.2    Ziepert, M.3    Schmits, R.4    Mohren, M.5    Lengfelder, E.6
  • 4
    • 23044503407 scopus 로고    scopus 로고
    • Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the Groupe d'Etude des Lymphomes de l'Adulte
    • Feugier P, Van Hoof A, Sebban C, Solal-Celigny P, Bouabdallah R, Fermé C, et al. Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol. 2005; 23(18): 4117-26.
    • (2005) J Clin Oncol , vol.23 , Issue.18 , pp. 4117-4126
    • Feugier, P.1    Van Hoof, A.2    Sebban, C.3    Solal-Celigny, P.4    Bouabdallah, R.5    Fermé, C.6
  • 5
    • 33745982067 scopus 로고    scopus 로고
    • Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma
    • Habermann TM, Weller EA, Morrison VA, Gascoyne RD, Cassileth PA, Cohn JB, et al. Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma. J Clin Oncol. 2006; 24(19): 3121-7.
    • (2006) J Clin Oncol , vol.24 , Issue.19 , pp. 3121-3127
    • Habermann, T.M.1    Weller, E.A.2    Morrison, V.A.3    Gascoyne, R.D.4    Cassileth, P.A.5    Cohn, J.B.6
  • 6
    • 24644500086 scopus 로고    scopus 로고
    • Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia
    • Sehn LH, Donaldson J, Chhanabhai M, Fitzgerald C, Gill K, Klasa R, et al. Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia. J Clin Oncol. 2005; 23(22): 5027-33.
    • (2005) J Clin Oncol , vol.23 , Issue.22 , pp. 5027-5033
    • Sehn, L.H.1    Donaldson, J.2    Chhanabhai, M.3    Fitzgerald, C.4    Gill, K.5    Klasa, R.6
  • 7
    • 33646004738 scopus 로고    scopus 로고
    • CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: A randomised controlled trial by the MabThera International Trial (MInT) Group
    • Pfreundschuh M, Trümper L, Osterborg A, Pettengell R, Trneny M, Imrie K, et al. CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol. 2006; 7(5): 379-91.
    • (2006) Lancet Oncol , vol.7 , Issue.5 , pp. 379-391
    • Pfreundschuh, M.1    Trümper, L.2    Osterborg, A.3    Pettengell, R.4    Trneny, M.5    Imrie, K.6
  • 8
    • 84876987456 scopus 로고    scopus 로고
    • Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): A randomised phase 3 trial
    • Delarue R, Tilly H, Mounier N, Petrella T, Salles G, Thieblemont C, et al. Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): a randomised phase 3 trial. Lancet Oncol. 2013; 14(6): 525-33.
    • (2013) Lancet Oncol , vol.14 , Issue.6 , pp. 525-533
    • Delarue, R.1    Tilly, H.2    Mounier, N.3    Petrella, T.4    Salles, G.5    Thieblemont, C.6
  • 9
    • 70349128174 scopus 로고    scopus 로고
    • Dosedense and high-dose chemotherapy plus rituximab with autologous stem cell transplantation for primary treatment of diffuse large B-cell lymphoma with a poor prognosis: A phase II multicenter study
    • Vitolo U, Chiappella A, Angelucci E, Rossi G, Liberati AM, Cabras MG, et al. Dosedense and high-dose chemotherapy plus rituximab with autologous stem cell transplantation for primary treatment of diffuse large B-cell lymphoma with a poor prognosis: a phase II multicenter study. Haematologica. 2009; 94(9): 1250-8.
    • (2009) Haematologica , vol.94 , Issue.9 , pp. 1250-1258
    • Vitolo, U.1    Chiappella, A.2    Angelucci, E.3    Rossi, G.4    Liberati, A.M.5    Cabras, M.G.6
  • 10
    • 34249065628 scopus 로고    scopus 로고
    • High-dose chemotherapy with autologous stem cell support in first-line treatment of aggressive non-Hodgkin lymphoma-results of a comprehensive meta-analysis
    • Greb A, Bohlius J, Trelle S, Schiefer D, De Souza CA, Gisselbrecht C, et al. High-dose chemotherapy with autologous stem cell support in first-line treatment of aggressive non-Hodgkin lymphoma-results of a comprehensive meta-analysis. Cancer Treat Rev. 2007; 33(4): 338-46.
    • (2007) Cancer Treat Rev , vol.33 , Issue.4 , pp. 338-346
    • Greb, A.1    Bohlius, J.2    Trelle, S.3    Schiefer, D.4    De Souza, C.A.5    Gisselbrecht, C.6
  • 11
    • 79959722615 scopus 로고    scopus 로고
    • An international phase II trial of single-agent lenalidomide for relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma
    • Witzig TE, Vose JM, Zinzani PL, Reeder CB, Buckstein R, Polikoff JA, et al. An international phase II trial of single-agent lenalidomide for relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma. Ann Oncol. 2011; 22(7): 1622-7.
    • (2011) Ann Oncol , vol.22 , Issue.7 , pp. 1622-1627
    • Witzig, T.E.1    Vose, J.M.2    Zinzani, P.L.3    Reeder, C.B.4    Buckstein, R.5    Polikoff, J.A.6
  • 12
    • 34347378243 scopus 로고    scopus 로고
    • How I treat patients with diffuse large B-cell lymphoma
    • Armitage JO. How I treat patients with diffuse large B-cell lymphoma. Blood. 2007; 110(1): 29-36.
    • (2007) Blood , vol.110 , Issue.1 , pp. 29-36
    • Armitage, J.O.1
  • 14
    • 84859413755 scopus 로고    scopus 로고
    • Relapsed/refractory diffuse large B-cell lymphoma
    • Friedberg JW. Relapsed/refractory diffuse large B-cell lymphoma. Hematology Am Soc Hematol Educ Program. 2011; 2011: 498-505.
    • (2011) Hematology Am Soc Hematol Educ Program , vol.2011 , pp. 498-505
    • Friedberg, J.W.1
  • 15
    • 0037444106 scopus 로고    scopus 로고
    • Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro
    • Haslett PA, Hanekom WA, Muller G, Kaplan G. Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro. J Infect Dis. 2003; 187(6): 946-55.
    • (2003) J Infect Dis , vol.187 , Issue.6 , pp. 946-955
    • Haslett, P.A.1    Hanekom, W.A.2    Muller, G.3    Kaplan, G.4
  • 16
    • 20144388765 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells in multiple myeloma: Implications and significance
    • Zhang H, Vakil V, Braunstein M, Smith EL, Maroney J, Chen L, et al. Circulating endothelial progenitor cells in multiple myeloma: implications and significance. Blood. 2005; 105(8): 3286-94.
    • (2005) Blood , vol.105 , Issue.8 , pp. 3286-3294
    • Zhang, H.1    Vakil, V.2    Braunstein, M.3    Smith, E.L.4    Maroney, J.5    Chen, L.6
  • 17
    • 81855205481 scopus 로고    scopus 로고
    • Lenalidomide induces capping of CD20 and cytoskeleton proteins to enhance rituximab immune recognition of malignant Bcells
    • abstract 2845
    • Gaidarova S, Mendy D, Heise C, Aukerman SL, Daniel T, Chopra R, et al. Lenalidomide induces capping of CD20 and cytoskeleton proteins to enhance rituximab immune recognition of malignant Bcells. Blood. 2010; 116: abstract 2845.
    • (2010) Blood , vol.116
    • Gaidarova, S.1    Mendy, D.2    Heise, C.3    Aukerman, S.L.4    Daniel, T.5    Chopra, R.6
  • 18
    • 34547474047 scopus 로고    scopus 로고
    • Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q-syndrome patients
    • Pellagatti A, Jadersten M, Forsblom AM, Cattan H, Christensson B, Emanuelsson EK, et al. Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q-syndrome patients. Proc Natl Acad Sci USA. 2007; 104(27): 11406-11.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.27 , pp. 11406-11411
    • Pellagatti, A.1    Jadersten, M.2    Forsblom, A.M.3    Cattan, H.4    Christensson, B.5    Emanuelsson, E.K.6
  • 19
    • 54449095901 scopus 로고    scopus 로고
    • Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma
    • Wiernik PH, Lossos IS, Tuscano JM, Justice G, Vose JM, Cole CE, et al. Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma. J Clin Oncol. 2008; 26(30): 4952-7.
    • (2008) J Clin Oncol , vol.26 , Issue.30 , pp. 4952-4957
    • Wiernik, P.H.1    Lossos, I.S.2    Tuscano, J.M.3    Justice, G.4    Vose, J.M.5    Cole, C.E.6
  • 20
    • 64149112784 scopus 로고    scopus 로고
    • Lenalidomide oral monotherapy produces a high response rate in patients with relapsed or refractory mantle cell lymphoma
    • Habermann TM, Lossos IS, Justice G, Vose JM, Wiernik PH, McBride K, et al. Lenalidomide oral monotherapy produces a high response rate in patients with relapsed or refractory mantle cell lymphoma. Br J Haematol. 2009; 145(3): 344-9.
    • (2009) Br J Haematol , vol.145 , Issue.3 , pp. 344-349
    • Habermann, T.M.1    Lossos, I.S.2    Justice, G.3    Vose, J.M.4    Wiernik, P.H.5    McBride, K.6
  • 21
    • 77956321373 scopus 로고    scopus 로고
    • Rituximab-lenalidomide-dexamethasone induces complete and durable remission in relapsed refractory diffuse large B-cell non-Hodgkin lymphoma
    • Ivanov V, Tabouret E, Chuto G, Chetaille B, Fezoui H, Coso D, et al. Rituximab-lenalidomide-dexamethasone induces complete and durable remission in relapsed refractory diffuse large B-cell non-Hodgkin lymphoma. Leuk Lymphoma. 2010; 51(9): 1758-60.
    • (2010) Leuk Lymphoma , vol.51 , Issue.9 , pp. 1758-1760
    • Ivanov, V.1    Tabouret, E.2    Chuto, G.3    Chetaille, B.4    Fezoui, H.5    Coso, D.6
  • 22
    • 79960431409 scopus 로고    scopus 로고
    • Lenalidomide for relapsed/refractory peripheral T-cell lymphoma not otherwise specified
    • Zinzani PL, Pellegrini C, Broccoli A, Stefoni V, Gandolfi L, Quirini F, et al. Lenalidomide for relapsed/refractory peripheral T-cell lymphoma not otherwise specified. Leuk Lymphoma. 2011; 52(8): 1585-8.
    • (2011) Leuk Lymphoma , vol.52 , Issue.8 , pp. 1585-1588
    • Zinzani, P.L.1    Pellegrini, C.2    Broccoli, A.3    Stefoni, V.4    Gandolfi, L.5    Quirini, F.6
  • 23
    • 69549116054 scopus 로고    scopus 로고
    • Synergistic antitumor effects of lenalidomide and rituximab on mantle cell lymphoma in vitro and in vivo
    • Zhang L, Qian Z, Cai Z, Sun L, Wang H, Bartlett JB, et al. Synergistic antitumor effects of lenalidomide and rituximab on mantle cell lymphoma in vitro and in vivo. Am J Hematol. 2009; 84(9): 553-9.
    • (2009) Am J Hematol , vol.84 , Issue.9 , pp. 553-559
    • Zhang, L.1    Qian, Z.2    Cai, Z.3    Sun, L.4    Wang, H.5    Bartlett, J.B.6
  • 24
    • 23844435619 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model
    • Hernandez-Ilizaliturri FJ, Reddy N, Holkova B, Ottman E, Czuczman MS. Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model. Clin Cancer Res. 2005; 11(16): 5984-92.
    • (2005) Clin Cancer Res , vol.11 , Issue.16 , pp. 5984-5992
    • Hernandez-Ilizaliturri, F.J.1    Reddy, N.2    Holkova, B.3    Ottman, E.4    Czuczman, M.S.5
  • 25
    • 83555173455 scopus 로고    scopus 로고
    • Lenalidomide can be safely combined with R-CHOP (R2CHOP) in the initial chemotherapy for aggressive B-cell lymphomas: Phase I study
    • Nowakowski GS, LaPlant B, Habermann TM, Rivera CE, Macon WR, Inwards DJ, et al. Lenalidomide can be safely combined with R-CHOP (R2CHOP) in the initial chemotherapy for aggressive B-cell lymphomas: phase I study. Leukemia. 2011; 25(12): 1877-81.
    • (2011) Leukemia , vol.25 , Issue.12 , pp. 1877-1881
    • Nowakowski, G.S.1    LaPlant, B.2    Habermann, T.M.3    Rivera, C.E.4    Macon, W.R.5    Inwards, D.J.6
  • 26
    • 84873571469 scopus 로고    scopus 로고
    • Phase 1b study of lenalidomide in combination with rituximab-CHOP (R2-CHOP) in patients with B-cell lymphoma
    • Tilly H, Morschhauser F, Salles G, Casasnovas RO, Feugier P, Molina TJ, et al. Phase 1b study of lenalidomide in combination with rituximab-CHOP (R2-CHOP) in patients with B-cell lymphoma. Leukemia. 2013; 27(1): 252-5.
    • (2013) Leukemia , vol.27 , Issue.1 , pp. 252-255
    • Tilly, H.1    Morschhauser, F.2    Salles, G.3    Casasnovas, R.O.4    Feugier, P.5    Molina, T.J.6
  • 27
    • 33748974393 scopus 로고    scopus 로고
    • EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphomas and solid tumours
    • Aapro MS, Cameron DA, Pettengell R, Bohlius J, Creawford J, Ellis M, et al. EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphomas and solid tumours. Eur J Cancer. 2006; 42(15): 2433-53.
    • (2006) Eur J Cancer , vol.42 , Issue.15 , pp. 2433-2453
    • Aapro, M.S.1    Cameron, D.A.2    Pettengell, R.3    Bohlius, J.4    Creawford, J.5    Ellis, M.6
  • 28
    • 32544438620 scopus 로고    scopus 로고
    • Management of nodal diffuse large B-cell lymphomas: Practice guidelines from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation
    • Barosi G, Carella A, Lazzarino M, Marchetti M, Martelli M, Rambaldi A, et al. Management of nodal diffuse large B-cell lymphomas: practice guidelines from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation. Haematologica. 2006; 91 (1): 96-103.
    • (2006) Haematologica , vol.91 , Issue.1 , pp. 96-103
    • Barosi, G.1    Carella, A.2    Lazzarino, M.3    Marchetti, M.4    Martelli, M.5    Rambaldi, A.6
  • 29
    • 33644840022 scopus 로고    scopus 로고
    • Experimental designs for phase I and phase I/II dose-finding studies
    • O'Quigley J, Zohar S. Experimental designs for phase I and phase I/II dose-finding studies. Br J Cancer. 2006; 94(5): 609-13.
    • (2006) Br J Cancer , vol.94 , Issue.5 , pp. 609-613
    • O'Quigley, J.1    Zohar, S.2
  • 30
    • 0035888182 scopus 로고    scopus 로고
    • The continual reassessment method: Comparison of Bayesian stopping rules for dose-ranging studies
    • Zohar S, Chevret S. The continual reassessment method: comparison of Bayesian stopping rules for dose-ranging studies. Stat Med. 2001; 20(19): 2827-43.
    • (2001) Stat Med , vol.20 , Issue.19 , pp. 2827-2843
    • Zohar, S.1    Chevret, S.2
  • 31
    • 0042162006 scopus 로고    scopus 로고
    • Software to compute and conduct sequential Bayesian phase I or II dose-ranging clinical trials with stopping rules
    • Zohar S, Latouche A, Taconnet M, Chevret S. Software to compute and conduct sequential Bayesian phase I or II dose-ranging clinical trials with stopping rules. Comput Methods Programs Biomed. 2003; 72(2): 117-25.
    • (2003) Comput Methods Programs Biomed , vol.72 , Issue.2 , pp. 117-125
    • Zohar, S.1    Latouche, A.2    Taconnet, M.3    Chevret, S.4
  • 32
    • 0024536437 scopus 로고
    • Optimal two-stage designs for phase II clinical trials
    • Simon R. Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989; 10(1): 1-10.
    • (1989) Control Clin Trials , vol.10 , Issue.1 , pp. 1-10
    • Simon, R.1
  • 33
    • 84859094786 scopus 로고    scopus 로고
    • Cyclo-phosphamide, doxorubicin, vincristine, prednisone and rituximab versus epirubicin, cyclophosphamide, vinblastine, prednisone and rituximab for the initial treatment of elderly "fit" patients with diffuse large B-cell lymphoma: Results from the ANZINTER3 trial of the Intergruppo Italiano Linfomi
    • Merli F, Luminari S, Rossi G, Mammi C, Marcheselli L, Tucci A, et al. Cyclo-phosphamide, doxorubicin, vincristine, prednisone and rituximab versus epirubicin, cyclophosphamide, vinblastine, prednisone and rituximab for the initial treatment of elderly "fit" patients with diffuse large B-cell lymphoma: results from the ANZINTER3 trial of the Intergruppo Italiano Linfomi. Leuk Lymphoma. 2012; 53(4): 581-8.
    • (2012) Leuk Lymphoma , vol.53 , Issue.4 , pp. 581-588
    • Merli, F.1    Luminari, S.2    Rossi, G.3    Mammi, C.4    Marcheselli, L.5    Tucci, A.6
  • 34
    • 0037165261 scopus 로고    scopus 로고
    • CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma
    • Coiffier B, Lepage E, Brière J, Herbrecht R, Tilly H, Bouabdallah R, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 2002; 346(4): 235-42.
    • (2002) N Engl J Med , vol.346 , Issue.4 , pp. 235-242
    • Coiffier, B.1    Lepage, E.2    Brière, J.3    Herbrecht, R.4    Tilly, H.5    Bouabdallah, R.6
  • 35
    • 33750607347 scopus 로고    scopus 로고
    • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • Richardson PG, Blood E, Mitsiades CS, Jagannath S, Zeldenrust SR, Alsina M, et al. A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood. 2006; 108(10): 3458-64.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3458-3464
    • Richardson, P.G.1    Blood, E.2    Mitsiades, C.S.3    Jagannath, S.4    Zeldenrust, S.R.5    Alsina, M.6
  • 36
    • 45949100928 scopus 로고    scopus 로고
    • Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
    • Ferrajoli A, Lee BN, Schlette EJ, O'Brien SM, Gao H, Wen S, et al. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood. 2008; 111(11): 5291-7.
    • (2008) Blood , vol.111 , Issue.11 , pp. 5291-5297
    • Ferrajoli, A.1    Lee, B.N.2    Schlette, E.J.3    O'Brien, S.M.4    Gao, H.5    Wen, S.6
  • 37
    • 84857654592 scopus 로고    scopus 로고
    • Combination of lenalidomide and rituximab in elderly patients with relapsed or refractory diffuse large B-cell lymphoma: A phase 2 trial
    • Zinzani PL, Pellegrini C, Gandolfi L, Stefoni V, Quirini F, Derenzini E, et al. Combination of lenalidomide and rituximab in elderly patients with relapsed or refractory diffuse large B-cell lymphoma: a phase 2 trial. Clin Lymphoma Myeloma Leuk. 2011; 11(6): 462-6.
    • (2011) Clin Lymphoma Myeloma Leuk , vol.11 , Issue.6 , pp. 462-466
    • Zinzani, P.L.1    Pellegrini, C.2    Gandolfi, L.3    Stefoni, V.4    Quirini, F.5    Derenzini, E.6
  • 38
    • 0036839013 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
    • Richardson PG, Schlossman RL, Weller E, Hideshima T, Mitsiades C, Davies F, et al. Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood. 2002; 100(9): 3063-7.
    • (2002) Blood , vol.100 , Issue.9 , pp. 3063-3067
    • Richardson, P.G.1    Schlossman, R.L.2    Weller, E.3    Hideshima, T.4    Mitsiades, C.5    Davies, F.6
  • 39
    • 80053502780 scopus 로고    scopus 로고
    • Higher response to lenalidomide in relapsed/refractory diffuse large B-cell lymphoma in nongerminal center B-cell-like than in germinal center B-cell-like phenotype
    • Hernandez-Ilizaliturri FJ, Deeb G, Zinzani PL, Pileri SA, Malik F, Macon WR, et al. Higher response to lenalidomide in relapsed/refractory diffuse large B-cell lymphoma in nongerminal center B-cell-like than in germinal center B-cell-like phenotype. Cancer. 2011; 117(22): 5058-66.
    • (2011) Cancer , vol.117 , Issue.22 , pp. 5058-5066
    • Hernandez-Ilizaliturri, F.J.1    Deeb, G.2    Zinzani, P.L.3    Pileri, S.A.4    Malik, F.5    Macon, W.R.6
  • 40
    • 78649594306 scopus 로고    scopus 로고
    • Phase 1 trial of bortezomib plus R-CHOP in previously untreated patients with aggressive non-Hodgkin lymphoma
    • Furman RR, Martin P, Ruan J, Cheung YK, Vose JM, LaCasce AS, et al. Phase 1 trial of bortezomib plus R-CHOP in previously untreated patients with aggressive non-Hodgkin lymphoma. Cancer. 2010; 116(23): 5432-9.
    • (2010) Cancer , vol.116 , Issue.23 , pp. 5432-5439
    • Furman, R.R.1    Martin, P.2    Ruan, J.3    Cheung, Y.K.4    Vose, J.M.5    LaCasce, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.