A worldwide survey to assess the current approach to the treatment of patients with cancer and venous thromboembolism

Thrombosis and Haemostasis

Volumn 110, Issue 5, 2013, Pages 959-965

  Kleinjan, Ankie ^a   Aggarwal, Anita ^c,d   van de Geer, Annemarie ^a   Faselis, Charles ^c,d   Büller, Harry R ^a   Di Nisio, Marcello ^a,b   Rickles, Frederick R ^c,d   Kamphuisen, Pieter Willem ^e  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF CHIETI   (Italy)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Anticoagulant treatment; Malignancy; Venous thrombosis

Indexed keywords

ANTICOAGULANT AGENT; ANTIVITAMIN K; FONDAPARINUX; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

ARTICLE; BLEEDING; BLOOD CLOT LYSIS; CLINICAL PRACTICE; COMPLIANCE (PHYSICAL); COMPUTER ASSISTED TOMOGRAPHY; DEEP VEIN THROMBOSIS; DRUG MEGADOSE; DRUG WITHDRAWAL; GENERAL PRACTITIONER; HEALTH CARE COST; HEMATOLOGY; HUMAN; INTERNAL MEDICINE; KIDNEY DISEASE; META ANALYSIS (TOPIC); MULTICENTER STUDY (TOPIC); NEOPLASM; ONCOLOGY; PRACTICE GUIDELINE; PRIMARY HEALTH CARE; PRIORITY JOURNAL; PULMONOLOGY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENT DISEASE; REIMBURSEMENT; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOSIS; VENOUS THROMBOEMBOLISM;

ANTICOAGULANT TREATMENT; MALIGNANCY; VENOUS THROMBOSIS;

ANTICOAGULANTS; DATA COLLECTION; DRUG DOSAGE CALCULATIONS; EUROPE; HEMATOLOGY; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; MEDICAL ONCOLOGY; NEOPLASMS; TIME FACTORS; UNITED STATES; VENOUS THROMBOEMBOLISM;

EID: 84887011419     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-05-0414     Document Type: Article

References (34)

1. Heit JA, O'Fallon WM, Petterson TM, et al. Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a population-based study. Arch Intern Med 2002; 162: 1245-1248.
2. Heit JA, Silverstein MD, Mohr DN, et al. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med 2000; 160: 809-815.
3. Levitan N, Dowlati A, Remick SC, et al. Rates of initial and recurrent thromboembolic disease among patients with malignancy versus those without malignancy. Risk analysis using Medicare claims data. Medicine 1999; 78: 285-291.
4. Otten HM, Mathijssen J, ten Cate H, et al. Symptomatic venous thromboembolism in cancer patients treated with chemotherapy: an underestimated phenomenon. Arch Intern Med 2004; 164: 190-194.
5. Büller HR, van Doormaal FF, van Sluis GL, et al. Cancer and thrombosis: from molecular mechanisms to clinical presentations. J Thromb Haemost 2007; 5 (Suppl 1): 246-254.
6. Khorana AA, Francis CW, Culakova E, et al. Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy. J Thromb Haemost 2007; 5: 632-634.
7. Walshe LJ, Malak SF, Eagan J, et al. Complication rates among cancer patients with peripherally inserted central catheters. J Clin Oncol 2002; 20: 3276-3281.
8. Ambrus JL, Ambrus CM, Mink IB, et al. Causes of death in cancer patients. J Med 1975; 6: 61-64.
9. Prandoni P, Lensing AW, Piccioli A, et al. Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. Blood 2002; 100: 3484-3488.
10. Lee AY, Levine MN, Baker RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 2003; 349: 146-153.
11. Meyer G, Marjanovic Z, Valcke J, et al. Comparison of low-molecular-weight heparin and warfarin for the secondary prevention of venous thromboembolism in patients with cancer: a randomized controlled study. Arch Intern Med 2002; 162: 1729-1735.
12. Deitcher SR, Kessler CM, Merli G, et al. Secondary prevention of venous thromboembolic events in patients with active cancer: enoxaparin alone versus initial enoxaparin followed by warfarin for a 180-day period. Clin Appl Thromb Hemost 2006; 12: 389-396.
13. Hull RD, Pineo GF, Brant RF, et al. Long-term low-molecular-weight heparin versus usual care in proximal-vein thrombosis patients with cancer. Am J Med 2006; 119: 1062-1072.
14. Akl EA, Labedi N, Barba M, et al. Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer. Cochrane Database Syst Rev 2011; 6: CD006650.
15. Hutten BA, Prins MH, Gent M, et al. Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved international normalized ratio: a retrospective analysis. J Clin Oncol 2000; 18: 3078-3083.
16. Lyman GH, Khorana AA, Falanga A, et al. American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J Clin Oncol 2007; 25: 5490-5505.
17. Kearon C, Akl EA, Comerota AJ, et al. Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141 (2 Suppl): e419S-e494S.
18. Prandoni P. How I treat venous thromboembolism in patients with cancer. Blood 2005; 106: 4027-4033.
19. den Exter PL, Hooijer J, Dekkers OM, et al. Risk of recurrent venous thromboembolism and mortality in patients with cancer incidentally diagnosed with pulmonary embolism: a comparison with symptomatic patients. J Clin Oncol 2011; 29: 2405-2409.
20. Gardner MJ, Altman DG. Statistics with confidence-Confidence intervals and statistical guidelines. Br Med J 1989; 17.
21. Kakkar AK, Levine M, Pinedo HM, et al. Venous thrombosis in cancer patients: insights from the FRONTLINE survey. Oncologist 2003; 8: 381-388.
22. Kirwan CC, Nath E, Byrne GJ, et al. Prophylaxis for venous thromboembolism during treatment for cancer: questionnaire survey. Br Med J 2003; 327: 597-598.
23. Johnson TP, Wislar JS. Response rates and nonresponse errors in surveys. J Am Med Assoc 2012; 307: 1805-1806.
24. Palareti G, Legnani C, Lee A, et al. A comparison of the safety and efficacy of oral anticoagulation for the treatment of venous thromboembolic disease in patients with or without malignancy. Thromb Haemost 2000; 84: 805-810.
25. Kamphuisen P. Longheva study. Available at: http://clinicaltrials. gov/ct2/show/NCT01164046. 2012. Accessed July 16, 2012.
26. Schulman S. Registry on recurrent VTE in cancer. Available at: http://www. isth. org/default/index. cfm/publications/registries-databases/recurrent-venousthromboembolism/2012. Accessed July 16, 2012.
27. van Doormaal FF, Raskob GE, Davidson BL, et al. Treatment of venous thromboembolism in patients with cancer: subgroup analysis of the Matisse clinical trials. Thromb Haemost 2009; 101: 762-769.
28. van Doormaal FF, Cohen AT, Davidson BL, et al. Idraparinux versus standard therapy in the treatment of deep venous thrombosis in cancer patients: a subgroup analysis of the Van Gogh DVT trial. Thromb Haemost 2010; 104: 86-91.
29. Sponsor Daiichi Sankyo Inc. Hokusai trial registration record. Available at: http://clinicaltrials. gov/ct2/show/NCT00986154. 2012. Accessed July 16, 2012.
30. Kovacs MJ, Kahn SR, Rodger M, et al. A pilot study of central venous catheter survival in cancer patients using low-molecular-weight heparin (dalteparin) and warfarin without catheter removal for the treatment of upper extremity deep vein thrombosis (The Catheter Study). J Thromb Haemost 2007; 5: 1650-1653.
31. Savage KJ, Wells PS, Schulz V, et al. Outpatient use of low molecular weight heparin (Dalteparin) for the treatment of deep vein thrombosis of the upper extremity. Thromb Haemost 1999; 82: 1008-1010.
32. Rathbun SW, Stoner JA, Whitsett TL. Treatment of upper-extremity deep vein thrombosis. J Thromb Haemost 2011; 9: 1924-1930.
33. Cronin CG, Lohan DG, Keane M, et al. Prevalence and significance of asymptomatic venous thromboembolic disease found on oncologic staging CT. AJR Am J Roentgenol 2007; 189: 162-170.
34. Di Nisio M, Ferrante N, De Tursi M, et al. Incidental venous thromboembolism in ambulatory cancer patients receiving chemotherapy. Thromb Haemost 2010; 104: 1049-1054.