Development of a procedure for the isolation and enrichment of modified nucleosides and nucleobases from urine prior to their determination by capillary electrophoresis-mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 489-496

  Rodríguez Gonzalo, Encarnación ^a   Hernández Prieto, Raquel ^a   García Gómez, Diego ^a   Carabias Martínez, Rita ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Capillary electrophoresis; Mass spectrometry; Nucleosides; Polymeric sorbents; Solid phase extraction; Urine

Indexed keywords

1 METHYLADENOSINE; 7 METHYLGUANINE; 7 METHYLGUANOSINE; 9 METHYLGUANINE; ADENOSINE; CYTIDINE; GUANINE; NUCLEIC ACID BASE; NUCLEOSIDE; POLYMER; SOLVENT; SORBENT; STYRENE;

ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; HUMAN; HYDROPHOBICITY; LIMIT OF DETECTION; NORMAL HUMAN; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; URINALYSIS;

CAPILLARY ELECTROPHORESIS; MASS SPECTROMETRY; NUCLEOSIDES; POLYMERIC SORBENTS; SOLID-PHASE EXTRACTION; URINE;

CALIBRATION; CHEMISTRY TECHNIQUES, ANALYTICAL; ELECTROPHORESIS, CAPILLARY; HEALTHY VOLUNTEERS; HUMANS; HYDROXYLATION; MASS SPECTROMETRY; NUCLEOSIDES; POLYMERS; POLYSTYRENES; REFERENCE STANDARDS; REGRESSION ANALYSIS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STYRENES; URINALYSIS;

EID: 84887010338     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.10.001     Document Type: Article

References (30)

1. Oerlemans F., Lange F. Major and modified nucleosides as markers in ovarian cancer: a pilot study. Gynecol. Obstet. Invest. 1986, 22:212-217.
2. Rasmuson T., Bjork G.R., Damber L., Jacobsson L., Jeppsson A., Stigbrand T., Westman G. Tumor markers in mammary carcinoma. Acta Oncol. 1987, 26:261-267.
3. Rasmuson T., Bjork G.R. Urinary excretion of pseudouridine and prognosis of patients with malignant lymphoma. Acta Oncol. 1995, 34:61-67.
4. McEntire J.E., Kuo K.C., Smith M.E., Stalling D.L., Richens J.W., Zumwalt R.W., Gehrke C.W., Papermaster B.W. Classification of lung cancer patients and controls by chromatography of modified nucleosides in serum. Cancer Res. 1989, 49:1057-1062.
5. Kvist E., Sjolin K.E., Iversen J., Nyholm K. Urinary excretion patterns of pseudouridine and beta-aminoisobutyric acid in patients with tumours of the urinary bladder. Urol. Nephrol. 1993, 27:45-53.
6. Nakano K., Nakao T., Schram K.H., Hammargren W.M., McClure T.D., Petersen E. Urinary excretion of modified nucleosides as biological marker of RNA turnover in patients with cancer and AIDS. Clin. Chim. Acta 1993, 218:169-183.
7. Xu G., Schmid H.R., Liebich H.M., Lu P. Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method. Biomed. Chromatogr. 2000, 14:459-463.
8. Yang J., Xu G.W., Zheng Y.F., Kong H., Pang T., Lv S., Yang Q. Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases. J. Chromatogr. B 2004, 813:59-65.
9. Chen M.L., Wei S-S., Yuan B.-F., Feng Y-Q. Preparation of methacrylate-based monolith for capillary hydrophilic interaction chromatography and its application in determination of nucleosides in urine. J. Chromatogr. A 2012, 1228:183-192.
10. Dudley E., Lemiere F., VanDongen W.R., Tuytten R.S., El-Sharkawi S., Brenton A.G., Esmans L., Newton R.P. Analysis of urinary nucleosides. IV. Identification of urinary purine nucleosides by liquid chromatography/electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 2004, 18:2730-2738.
11. Lee S.H., Jung B.H., Kim S.Y., Chung B.C. A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun. Mass Spectrom. 2004, 18:973-977.
12. Rodríguez-Gonzalo E., García-Gómez D., Carabias-Martínez R. Development and validation of a hydrophilic interaction chromatography-tandem mass spectrometry method with on-line polar extraction for the analysis of urinary nucleosides. Potential application in clinical diagnosis. J. Chromatogr. A 2011, 1218:9055-9063.
13. Studzinska S., Buszewski B. A new way to fast and high resolution determination of modified nucleosides. J. Chromatogr. B 2012, 887-888:93-101.
14. Struck W., Siluk D., Yumba-Mpanga A., Markuszewski M., Kaliszan R., Jan Markuszewski M. Liquid chromatography tandem mass spectrometry study of urinary nucleosides as potential cancer markers. J. Chromatogr. A 2013, 1283:122-131.
15. Zhao R.G., Xu G.B., Yue B., Liebich H.M., Zhang Y. Artificial neural network classification based on capillary electrophoresis of urinary nucleosides for the clinical diagnosis of tumours. J. Chromatogr. A 1998, 828:489-496.
16. Zheng Y.F., Kong H.W., Xiong J.H., Lv S., Xu G.W. Clinical significance and prognostic value of urinary nucleosides in breast cancer patients. Clin. Biochem. 2005, 38:24-30.
17. Zheng Y.F., Xu G.W., Liu D.Y., Xiong J.H., Zhang P.D., Zhang C., Yang Q., Lv S. Study of urinary nucleosides as biological marker in cancer patients analyzed by micellar electrokinetic capillary chromatography. Electrophoresis 2002, 23:4104-4109.
18. Liebich H.M., Xu G., Stefano C.D., Lehmann R. Capillary electrophoresis of urinary normal and modified nucleosides of cancer patients. J. Chromatogr. A 1998, 793:341-347.
19. Liebich H.M., Lehmann R., Xu G., Wahl H.G., Häring H.-U. Application of capillary electrophoresis in clinical chemistry: the clinical value of urinary modified nucleosides. J. Chromatogr. B 2000, 745:189-196.
20. La S., Cho J.H., Kim J.-H., Kim K.-R. Capillary electrophoretic profiling and pattern recognition analysis of urinary nucleosides from thyroid cancer patients. Anal. Chim. Acta 2003, 486:171-182.
21. Jiang Y., Ma Y. A fast capillary electrophoresis method for separation and quantification of modified nucleosides in urinary samples. Anal. Chem. 2009, 81:6474-6480.
22. Hernández-Prieto R., García-Gómez D., Rodríguez-Gonzalo E., Carabias-Martínez R. Capillary electrophoresis with mass spectrometric detection for the determination of urinary levels of modified nucleoside. Communication Presented at Euroanalysis XVI 2012.
23. Liebich H.M., Müller-Hagedorn S., Klaus F., Meziane K., Kimb K.-R., Frickenschmidt A., Kammerer B. Chromatographic, capillary electrophoretic and matrix-assisted laser desorption ionization time-of-flight mass spectrometry analysis of urinary modified nucleosides as tumor markers. J. Chromatogr. A 2005, 1071:271-275.
24. Szymanska E., Markuszewski M.J., Bodzioch K., Kaliszan R. Development and validation of urinary nucleosides and creatinine assay by capillary electrophoresis with solid phase extraction. J. Pharm. Biomed. Anal. 2007, 44:1118-1126.
25. Mao Y., Zhao X., Wang S., Cheng Y. Urinary nucleosides based potential biomarker selection by support vector machine for bladder cancer recognition. Anal. Chim. Acta 2007, 598:34-40.
26. Tuytten R., Lemière F., Esmans E.L., Herrebout W.A., van der Veken B.J., Maes B.U.W., Witters E., Newton R.P., Dudley E. Role of nitrogen Lewis basicity in boronate affinity chromatography of nucleosides. Anal. Chem. 2007, 79:6662-6669.
27. Wang S., Zhaob X., Mao Y., Cheng Y. Novel approach for developing urinary nucleosides profile by capillary electrophoresis-mass spectrometry. J. Chromatogr. A 2007, 1147:254-260.
28. Weiss D.J., Lunte C.E. Detection of a urinary biomaker for oxidative DNA damage 8-hydroxydeoxyguanosine by capillary electrophoresis with electrochemical detection. Electrophoresis 2000, 21:2080-2085.
29. Jeng L.-B., Lo W.-Y., Hsu W.-Y., Lin W.-D., Lin C.-T., Lai C.-C., Tsai F.-J. Analysis of urinary nucleosides as helper tumor markers in hepatocellular carcinoma diagnosis. Rapid Commun. Mass Spectrom. 2009, 23:1543-1549.
30. van de Merbel N.C. Quantitative determination of endogenous compounds in biological samples using chromatographic techniques. Trends Anal. Chem. 2008, 27:924-933.