Verification of IL-17A and IL-17F in oral tissues and modulation of their expression pattern by steroid hormones

Cellular Immunology

Volumn 285, Issue 1-2, 2013, Pages 133-140

  Konermann, Anna ^a   Winter, Jochen ^b   Novak, Natalija ^a   Allam, Jean Pierre ^a   Jäger, Andreas ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Estradiol; IL 17; Immunomodulation; Periodontal tissues; Testosterone

Indexed keywords

ANDROGEN RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 17F; INTERLEUKIN 1BETA; TESTOSTERONE; IL17A PROTEIN, HUMAN; IL17F PROTEIN, HUMAN; INTERLEUKIN 17;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; FIBROBLAST; GENE EXPRESSION PROFILING; GINGIVA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; NORMAL HUMAN; PERIODONTAL LIGAMENT; PERIODONTIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; PERIODONTAL TISSUES;

ESTRADIOL; IL-17; IMMUNOMODULATION; PERIODONTAL TISSUES; TESTOSTERONE;

CELLS, CULTURED; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; GINGIVA; HUMANS; INFLAMMATION; INTERLEUKIN-17; MALE; PERIODONTAL LIGAMENT; PERIODONTIUM; TESTOSTERONE;

EID: 84886995235     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2013.10.004     Document Type: Article

References (41)

1. Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell mediated tissue damage. Nat. Med. 2007, 13:139-145.
2. Gaffen S.L. Structure and signalling in the IL-17 receptor family. Nat. Rev. Immunol. 2009, 9:556-567.
3. Sato K., Suematsu A., Okamoto K., Yamaguchi A., Morishita Y., Kadono Y., Tanaka S., Kodama T., Akira S., Iwakura Y., Cua D.J., Takayanagi H. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 2006, 203:2673-2682.
4. Ishigame H., Kakuta S., Nagai T., Kadoki M., Nambu A., Komiyama Y., Fujikado N., Tanahashi Y., Akitsu A., Kotaki H., Sudo K., Nakae S., Sasakawa C., Iwakura Y. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 2009, 30:108-119.
5. Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., Cua D.J., Littman D.R. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
6. Iwakura Y., Ishigame H., Saijo S., Nakae S. Functional specialization of interleukin-17 family members. Immunity 2011, 34:149-162.
7. Gaffen S.L. Recent advances in the IL-17 cytokine family. Curr. Opin. Immunol. 2011, 23:613-619.
8. Takahashi N., Vanlaere I., de Rycke R., Cauwels A., Joosten L.A., Lubberts E., van den Berg W.B., Libert C. IL-17 produced by paneth cells drives TNF-induced shock. J. Exp. Med. 2008, 205:1755-1761.
9. Cua D.J., Tato C.M. Innate IL-17-producing cells: the sentinels of the immune system. Nat. Rev. Immunol. 2010, 10:479-489.
10. Allam J.P., Duan Y., Heinemann F., Winter J., Götz W., Deschner J., Wenghoefer M., Bieber T., Jepsen S., Novak N. IL-23-producing CD68(+) macrophage-like cells predominate within an IL-17-polarized infiltrate in chronic periodontitis lesions. J. Clin. Periodontol. 2011, 38:879-886.
11. Cochran D.L. Inflammation and bone loss in periodontal disease. J. Periodontol. 2008, 79:1569-1576.
12. Coventry J., Griffiths G., Scully C., Tonetti M. ABC of oral health: periodontal disease. BMJ 2000, 321:36-39.
13. Honda T., Aoki Y., Takahashi N., Maekawa T., Nakajima T., Ito H., Tabeta K., Okui T., Kajita K., Domon H., Yamazaki K. Elevated expression of IL-17 and IL-12 genes in chronic inflammatory periodontal disease. Clin. Chim. Acta 2008, 395:137-141.
14. Lester S.R., Bain J.L., Johnson R.B., Serio F.G. Gingival concentrations of interleukin-23 and -17 at healthy sites and at sites of clinical attachment loss. J. Periodontol. 2007, 78:1545-1550.
15. Rizzoli R., Bonjour J.P., Ferrari S.L. Osteoporosis, genetics and hormones. J. Mol. Endocrinol. 2001, 26:79-94.
16. Mariotti A. Sex steroid hormones and cell dynamics in the periodontium. Crit. Rev. Oral Biol. Med. 1994, 5:27-53.
17. Beery T.A. Sex differences in infection and sepsis. Crit. Care Nurs. Clin. North Am. 2003, 15:55-62.
18. Marriott I., Huet-Hudson Y.M. Sexual dimorphism in innate immune responses to infectious organisms. Immunol. Res. 2006, 34:177-192.
19. Lapp C.A., Lapp D.F. Analysis of interleukin-activated human gingival fibroblasts: modulation of chemokine responses by female hormones. J. Periodontol. 2005, 76:803-812.
20. 2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells. Blood 2004, 104:1404-1410.
21. Beagley K.W., Gockel C.M. Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol. Med. Microbiol. 2003, 38:13-22.
22. Saika M., Inoue D., Kido S., Matsumoto T. 17beta-Estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-alpha. Endocrinology 2001, 142:2205-2212.
23. Angele M.K., Schwacha M.G., Ayala A., Chaudry I.H. Effect of gender and sex hormones on immune responses following shock. Shock 2000, 14:81-90.
24. Dane S., Timur H. Sex-related differences in tuberculin reaction, free and total testosterone concentrations in patients with autoimmune disorders and controls. Int. J. Neurosci. 2005, 115:911-916.
25. Wu C.H., Motohashi T., Abdel-Rahman H.A., Flickinger G.L., Mikhail G. Free and protein-bound plasma estradiol-17β during the menstrual cycle. J. Clin. Endocrinol. Metab. 1976, 43:436-445.
26. Khosla S., Melton L.J., Atkinson E.J., O'Fallon W.M. Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men. J. Clin. Endocrinol. Metab. 2001, 86:3555-3561.
27. Oh J.A., Shin H.S. Rapid determination of natural steroidal hormones in saliva for the clinical diagnoses. Chem. Cent. J. 2012, 6:22.
28. Asikainen P., Ruotsalainen T.J., Mikkonen J.J., Koistinen A., Ten Bruggenkate C., Kullaa A.M. The defence architecture of the superficial cells of the oral mucosa. Med. Hypotheses 2012, 78:790-792.
29. Nomura Y., Ishikawa M., Yashiro Y., Sanggarnjanavanich S., Yamaguchi T., Arai C., Noda K., Takano Y., Nakamura Y., Hanada N. Human periodontal ligament fibroblasts are the optimal cell source for induced pluripotent stem cells. Histochem. Cell Biol. 2012, 137:719-732.
30. Konermann A., Beyer M., Deschner J., Allam J.P., Novak N., Winter J., Jepsen S., Jäger A. Human periodontal ligament cells facilitate leukocyte recruitment and are influenced in their immunomodulatory function by Th17 cytokine release. Cell. Immunol. 2012, 272:137-143.
31. Konermann A., Deschner J., Allam J.P., Novak N., Winter J., Baader S.L., Jepsen S., Jäger A. Antigen-presenting cell marker expression and phagocytotic activity in periodontal ligament cells. J. Oral Pathol. Med. 2012, 41:340-347.
32. Krisanaprakornkit S., Weinberg A., Perez C.N., Dale B.A. Expression of the peptide antibiotic human β-defensin 1 in cultured gingival epithelial cells and gingival tissue. Infect. Immun. 1998, 66:4222-4228.
33. Lossdörfer S., Götz W., Jäger A. PTH(1-34) affects osteoprotegerin production in human PDL cells in vitro. J. Dent. Res. 2005, 84:634-638.
34. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
35. Tam S.P., Archer T.K., Deeley R.G. Biphasic effects of estrogen on apolipoprotein synthesis in human hepatoma cells: mechanism of antagonism by testosterone. Proc. Natl. Acad. Sci. USA 1986, 83:3111-3115.
36. Edmunds S.E., Stubbs A.P., Santos A.A., Wilkinson M.L. Estrogen and androgen regulation of sex hormone binding globulin secretion by a human liver cell line. J. Steroid Mol. Biol. 1990, 37:733-739.
37. Gornstein R.A., Lapp C.A., Bustos-Valdes S.M., Zamorano P. Androgens modulate interleukin-6 production by gingival fibroblasts in vitro. J. Periodontol. 1999, 70:604-609.
38. Oh J.A., Shin H.S. Rapid determination of natural steroidal hormones in saliva for the clinical diagnoses. Chem. Cent. J. 2012, 6:22.
39. Sutton C.E., Mielke L.A., Mills K.H. KH, IL-17-producing γδ T cells and innate lymphoid cells. Eur. J. Immunol. 2012, 42:2221-2231.
40. Li H., Reeves R.K. Functional perturbation of classical natural killer and innate lymphoid cells in the oral mucosa during SIV infection. Front. Immunol. 2012, 3:417.
41. Cella M., Otero K., Colonna M. Expansion of human NK-22 cells with IL-7 IL-2 and IL-1beta reveals intrinsic functional plasticity. Proc. Natl. Acad. Sci. USA 2010, 107:10961-10966.