-
1
-
-
0033617522
-
Notch signaling: cell fate control and signal integration in development
-
Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 1999, 284(5415):770-776.
-
(1999)
Science
, vol.284
, Issue.5415
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
2
-
-
1642382833
-
Notch signaling: control of cell communication and cell fate
-
Lai E.C. Notch signaling: control of cell communication and cell fate. Development 2004, 131(5):965-973.
-
(2004)
Development
, vol.131
, Issue.5
, pp. 965-973
-
-
Lai, E.C.1
-
3
-
-
33747623018
-
Notch signalling: a simple pathway becomes complex
-
Bray S.J. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 2006, 7(9):678-689.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.9
, pp. 678-689
-
-
Bray, S.J.1
-
4
-
-
64249172203
-
The canonical Notch signaling pathway: unfolding the activation mechanism
-
Kopan R., Ilagan M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009, 137(2):216-233.
-
(2009)
Cell
, vol.137
, Issue.2
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
5
-
-
68549115658
-
Notch signaling controls liver development by regulating biliary differentiation
-
Zong Y., Panikkar A., Xu J., Antoniou A., Raynaud P., Lemaigre F., et al. Notch signaling controls liver development by regulating biliary differentiation. Development 2009, 136(10):1727-1739.
-
(2009)
Development
, vol.136
, Issue.10
, pp. 1727-1739
-
-
Zong, Y.1
Panikkar, A.2
Xu, J.3
Antoniou, A.4
Raynaud, P.5
Lemaigre, F.6
-
6
-
-
9644307844
-
The role of notch signaling in the development of intrahepatic bile ducts
-
Kodama Y., Hijikata M., Kageyama R., Shimotohno K., Chiba T. The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology 2004, 127(6):1775-1786.
-
(2004)
Gastroenterology
, vol.127
, Issue.6
, pp. 1775-1786
-
-
Kodama, Y.1
Hijikata, M.2
Kageyama, R.3
Shimotohno, K.4
Chiba, T.5
-
7
-
-
49649111405
-
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice
-
Geisler F., Nagl F., Mazur P.K., Lee M., Zimber-Strobl U., Strobl L.J., et al. Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology 2008, 48(2):607-616.
-
(2008)
Hepatology
, vol.48
, Issue.2
, pp. 607-616
-
-
Geisler, F.1
Nagl, F.2
Mazur, P.K.3
Lee, M.4
Zimber-Strobl, U.5
Strobl, L.J.6
-
8
-
-
46649119289
-
Notch signaling regulates bile duct morphogenesis in mice
-
Lozier J., McCright B., Gridley T. Notch signaling regulates bile duct morphogenesis in mice. PLoS One 2008, 3(3):e1851.
-
(2008)
PLoS One
, vol.3
, Issue.3
-
-
Lozier, J.1
McCright, B.2
Gridley, T.3
-
9
-
-
0036339631
-
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency
-
McCright B., Lozier J., Gridley T. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 2002, 129(4):1075-1082.
-
(2002)
Development
, vol.129
, Issue.4
, pp. 1075-1082
-
-
McCright, B.1
Lozier, J.2
Gridley, T.3
-
10
-
-
77950609317
-
Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice
-
Sparks E.E., Huppert K.A., Brown M.A., Washington M.K., Huppert S.S. Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology 2010, 51(4):1391-1400.
-
(2010)
Hepatology
, vol.51
, Issue.4
, pp. 1391-1400
-
-
Sparks, E.E.1
Huppert, K.A.2
Brown, M.A.3
Washington, M.K.4
Huppert, S.S.5
-
11
-
-
4344567112
-
Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors
-
Tanimizu N., Miyajima A. Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors. J Cell Sci 2004, 117(Pt 15):3165-3174.
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 15
, pp. 3165-3174
-
-
Tanimizu, N.1
Miyajima, A.2
-
12
-
-
78649873560
-
Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome
-
Hofmann J.J., Zovein A.C., Koh H., Radtke F., Weinmaster G., Iruela-Arispe M.L. Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development 2010, 137(23):4061-4072.
-
(2010)
Development
, vol.137
, Issue.23
, pp. 4061-4072
-
-
Hofmann, J.J.1
Zovein, A.C.2
Koh, H.3
Radtke, F.4
Weinmaster, G.5
Iruela-Arispe, M.L.6
-
13
-
-
33847729533
-
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage
-
Loomes K.M., Russo P., Ryan M., Nelson A., Underkoffler L., Glover C., et al. Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage. Hepatology 2007, 45(2):323-330.
-
(2007)
Hepatology
, vol.45
, Issue.2
, pp. 323-330
-
-
Loomes, K.M.1
Russo, P.2
Ryan, M.3
Nelson, A.4
Underkoffler, L.5
Glover, C.6
-
14
-
-
66149104013
-
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9
-
Antoniou A., Raynaud P., Cordi S., Zong Y., Tronche F., Stanger B.Z., et al. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology 2009, 136(7):2325-2333.
-
(2009)
Gastroenterology
, vol.136
, Issue.7
, pp. 2325-2333
-
-
Antoniou, A.1
Raynaud, P.2
Cordi, S.3
Zong, Y.4
Tronche, F.5
Stanger, B.Z.6
-
15
-
-
0036336513
-
Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta
-
Coffinier C., Gresh L., Fiette L., Tronche F., Schutz G., Babinet C., et al. Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta. Development 2002, 129(8):1829-1838.
-
(2002)
Development
, vol.129
, Issue.8
, pp. 1829-1838
-
-
Coffinier, C.1
Gresh, L.2
Fiette, L.3
Tronche, F.4
Schutz, G.5
Babinet, C.6
-
16
-
-
0038875342
-
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
-
Li L., Krantz I.D., Deng Y., Genin A., Banta A.B., Collins C.C., et al. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet 1997, 16(3):243-251.
-
(1997)
Nat Genet
, vol.16
, Issue.3
, pp. 243-251
-
-
Li, L.1
Krantz, I.D.2
Deng, Y.3
Genin, A.4
Banta, A.B.5
Collins, C.C.6
-
17
-
-
0030914459
-
Mutations in the human Jagged1 gene are responsible for Alagille syndrome
-
Oda T., Elkahloun A.G., Pike B.L., Okajima K., Krantz I.D., Genin A., et al. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat Genet 1997, 16(3):235-242.
-
(1997)
Nat Genet
, vol.16
, Issue.3
, pp. 235-242
-
-
Oda, T.1
Elkahloun, A.G.2
Pike, B.L.3
Okajima, K.4
Krantz, I.D.5
Genin, A.6
-
18
-
-
33745232796
-
NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway
-
McDaniell R., Warthen D.M., Sanchez-Lara P.A., Pai A., Krantz I.D., Piccoli D.A., et al. NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway. Am J Hum Genet 2006, 79(1):169-173.
-
(2006)
Am J Hum Genet
, vol.79
, Issue.1
, pp. 169-173
-
-
McDaniell, R.1
Warthen, D.M.2
Sanchez-Lara, P.A.3
Pai, A.4
Krantz, I.D.5
Piccoli, D.A.6
-
19
-
-
0034877469
-
Outcome of liver disease in children with Alagille syndrome: a study of 163 patients
-
Lykavieris P., Hadchouel M., Chardot C., Bernard O. Outcome of liver disease in children with Alagille syndrome: a study of 163 patients. Gut 2001, 49(3):431-435.
-
(2001)
Gut
, vol.49
, Issue.3
, pp. 431-435
-
-
Lykavieris, P.1
Hadchouel, M.2
Chardot, C.3
Bernard, O.4
-
20
-
-
34548324268
-
Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling
-
Fabris L., Cadamuro M., Guido M., Spirli C., Fiorotto R., Colledan M., et al. Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling. Am J Pathol 2007, 171(2):641-653.
-
(2007)
Am J Pathol
, vol.171
, Issue.2
, pp. 641-653
-
-
Fabris, L.1
Cadamuro, M.2
Guido, M.3
Spirli, C.4
Fiorotto, R.5
Colledan, M.6
-
21
-
-
84859614232
-
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
-
Boulter L., Govaere O., Bird T.G., Radulescu S., Ramachandran P., Pellicoro A., et al. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med 2012, 18(4):572-579.
-
(2012)
Nat Med
, vol.18
, Issue.4
, pp. 572-579
-
-
Boulter, L.1
Govaere, O.2
Bird, T.G.3
Radulescu, S.4
Ramachandran, P.5
Pellicoro, A.6
-
22
-
-
84879174086
-
Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice
-
[PMID 23500150, in press]
-
Fiorotto R., Raizner A., Morell C.M., Torsello B., Scirpo R., Fabris L., et al. Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice. J Hepatol 2013, [PMID 23500150, in press].
-
(2013)
J Hepatol
-
-
Fiorotto, R.1
Raizner, A.2
Morell, C.M.3
Torsello, B.4
Scirpo, R.5
Fabris, L.6
-
23
-
-
84871205953
-
The balance between Notch/Wnt signaling regulates progenitor cells' commitment during liver repair: mystery solved?
-
Strazzabosco M., Fabris L. The balance between Notch/Wnt signaling regulates progenitor cells' commitment during liver repair: mystery solved?. J Hepatol 2012, 58(1):181-183.
-
(2012)
J Hepatol
, vol.58
, Issue.1
, pp. 181-183
-
-
Strazzabosco, M.1
Fabris, L.2
-
24
-
-
84876145364
-
Constitutive Notch2 signaling induces hepatic tumors in mice
-
Dill M.T., Tornillo L., Fritzius T., Terracciano L., Semela D., Bettler B., et al. Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology 2013, 58(4):1607-1619.
-
(2013)
Hepatology
, vol.58
, Issue.4
, pp. 1607-1619
-
-
Dill, M.T.1
Tornillo, L.2
Fritzius, T.3
Terracciano, L.4
Semela, D.5
Bettler, B.6
-
25
-
-
84864773126
-
Cholangiocarcinomas can originate from hepatocytes in mice
-
Fan B., Malato Y., Calvisi D.F., Naqvi S., Razumilava N., Ribback S., et al. Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest 2012, 122(8):2911-2915.
-
(2012)
J Clin Invest
, vol.122
, Issue.8
, pp. 2911-2915
-
-
Fan, B.1
Malato, Y.2
Calvisi, D.F.3
Naqvi, S.4
Razumilava, N.5
Ribback, S.6
-
26
-
-
84868625552
-
Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes
-
Sekiya S., Suzuki A. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest 2012, 122(11):3914-3918.
-
(2012)
J Clin Invest
, vol.122
, Issue.11
, pp. 3914-3918
-
-
Sekiya, S.1
Suzuki, A.2
-
27
-
-
84869765074
-
Notch signaling in hepatocellular carcinoma: guilty in association!
-
Strazzabosco M., Fabris L. Notch signaling in hepatocellular carcinoma: guilty in association!. Gastroenterology 2012, 143(6):1430-1434.
-
(2012)
Gastroenterology
, vol.143
, Issue.6
, pp. 1430-1434
-
-
Strazzabosco, M.1
Fabris, L.2
-
28
-
-
84869774410
-
Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice
-
[e1667]
-
Villanueva A., Alsinet C., Yanger K., Hoshida Y., Zong Y., Toffanin S., et al. Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice. Gastroenterology 2012, 143(6):1660-1669. [e1667].
-
(2012)
Gastroenterology
, vol.143
, Issue.6
, pp. 1660-1669
-
-
Villanueva, A.1
Alsinet, C.2
Yanger, K.3
Hoshida, Y.4
Zong, Y.5
Toffanin, S.6
-
29
-
-
84877921803
-
Notch driven carcinogenesis: the merging of hepatocellular cancer and cholangiocarcinoma into a common molecular liver cancer subtype
-
Razumilava N., Gores G.J. Notch driven carcinogenesis: the merging of hepatocellular cancer and cholangiocarcinoma into a common molecular liver cancer subtype. J Hepatol 2013, 58(6):1244-1245.
-
(2013)
J Hepatol
, vol.58
, Issue.6
, pp. 1244-1245
-
-
Razumilava, N.1
Gores, G.J.2
-
30
-
-
0037213389
-
The role of hepatocytes and oval cells in liver regeneration and repopulation
-
Fausto N., Campbell J.S. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech Dev 2003, 120(1):117-130.
-
(2003)
Mech Dev
, vol.120
, Issue.1
, pp. 117-130
-
-
Fausto, N.1
Campbell, J.S.2
-
31
-
-
78651447817
-
Liver regeneration: alternative epithelial pathways
-
Michalopoulos G.K. Liver regeneration: alternative epithelial pathways. Int J Biochem Cell Biol 2011, 43(2):173-179.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, Issue.2
, pp. 173-179
-
-
Michalopoulos, G.K.1
-
33
-
-
2542595537
-
Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers
-
Roskams T.A., Theise N.D., Balabaud C., Bhagat G., Bhathal P.S., Bioulac-Sage P., et al. Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers. Hepatology 2004, 39(6):1739-1745.
-
(2004)
Hepatology
, vol.39
, Issue.6
, pp. 1739-1745
-
-
Roskams, T.A.1
Theise, N.D.2
Balabaud, C.3
Bhagat, G.4
Bhathal, P.S.5
Bioulac-Sage, P.6
-
34
-
-
66449086571
-
Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism
-
[e2311-3]
-
Burke Z.D., Reed K.R., Phesse T.J., Sansom O.J., Clarke A.R., Tosh D. Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism. Gastroenterology 2009, 136(7):2316-2324. [e2311-3].
-
(2009)
Gastroenterology
, vol.136
, Issue.7
, pp. 2316-2324
-
-
Burke, Z.D.1
Reed, K.R.2
Phesse, T.J.3
Sansom, O.J.4
Clarke, A.R.5
Tosh, D.6
-
35
-
-
0031730816
-
Ductular reaction and its diagnostic significance
-
Roskams T., Desmet V. Ductular reaction and its diagnostic significance. Semin Diagn Pathol 1998, 15(4):259-269.
-
(1998)
Semin Diagn Pathol
, vol.15
, Issue.4
, pp. 259-269
-
-
Roskams, T.1
Desmet, V.2
-
36
-
-
84859718543
-
Development of the bile ducts: essentials for the clinical hepatologist
-
Strazzabosco M., Fabris L. Development of the bile ducts: essentials for the clinical hepatologist. J Hepatol 2012, 56(5):1159-1170.
-
(2012)
J Hepatol
, vol.56
, Issue.5
, pp. 1159-1170
-
-
Strazzabosco, M.1
Fabris, L.2
-
37
-
-
79951900204
-
Epithelial-mesenchymal interactions in biliary diseases
-
Fabris L., Strazzabosco M. Epithelial-mesenchymal interactions in biliary diseases. Semin Liver Dis 2011, 31(1):11-32.
-
(2011)
Semin Liver Dis
, vol.31
, Issue.1
, pp. 11-32
-
-
Fabris, L.1
Strazzabosco, M.2
-
40
-
-
0035185449
-
Notch receptor expression in adult human liver: a possible role in bile duct formation and hepatic neovascularization
-
Nijjar S.S., Crosby H.A., Wallace L., Hubscher S.G., Strain A.J. Notch receptor expression in adult human liver: a possible role in bile duct formation and hepatic neovascularization. Hepatology 2001, 34(6):1184-1192.
-
(2001)
Hepatology
, vol.34
, Issue.6
, pp. 1184-1192
-
-
Nijjar, S.S.1
Crosby, H.A.2
Wallace, L.3
Hubscher, S.G.4
Strain, A.J.5
-
41
-
-
77149158796
-
Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling
-
Spee B., Carpino G., Schotanus B.A., Katoonizadeh A., Vander Borght S., Gaudio E., et al. Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling. Gut 2010, 59(2):247-257.
-
(2010)
Gut
, vol.59
, Issue.2
, pp. 247-257
-
-
Spee, B.1
Carpino, G.2
Schotanus, B.A.3
Katoonizadeh, A.4
Vander Borght, S.5
Gaudio, E.6
-
42
-
-
70349515743
-
The niche of stellate cells within rat liver
-
Sawitza I., Kordes C., Reister S., Haussinger D. The niche of stellate cells within rat liver. Hepatology 2009, 50(5):1617-1624.
-
(2009)
Hepatology
, vol.50
, Issue.5
, pp. 1617-1624
-
-
Sawitza, I.1
Kordes, C.2
Reister, S.3
Haussinger, D.4
-
43
-
-
84867068023
-
Inhibition of Notch signaling by a gamma-secretase inhibitor attenuates hepatic fibrosis in rats
-
Chen Y., Zheng S., Qi D., Zheng S., Guo J., Zhang S., et al. Inhibition of Notch signaling by a gamma-secretase inhibitor attenuates hepatic fibrosis in rats. PLoS One 2012, 7(10):e46512.
-
(2012)
PLoS One
, vol.7
, Issue.10
-
-
Chen, Y.1
Zheng, S.2
Qi, D.3
Zheng, S.4
Guo, J.5
Zhang, S.6
-
44
-
-
0036094234
-
Altered Notch ligand expression in human liver disease: further evidence for a role of the Notch signaling pathway in hepatic neovascularization and biliary ductular defects
-
Nijjar S.S., Wallace L., Crosby H.A., Hubscher S.G., Strain A.J. Altered Notch ligand expression in human liver disease: further evidence for a role of the Notch signaling pathway in hepatic neovascularization and biliary ductular defects. Am J Pathol 2002, 160(5):1695-1703.
-
(2002)
Am J Pathol
, vol.160
, Issue.5
, pp. 1695-1703
-
-
Nijjar, S.S.1
Wallace, L.2
Crosby, H.A.3
Hubscher, S.G.4
Strain, A.J.5
-
45
-
-
78149358943
-
Management of large hepatocellular carcinoma in adult patients with Alagille syndrome: a case report and review of literature
-
Tsai S., Gurakar A., Anders R., Lam-Himlin D., Boitnott J., Pawlik T.M. Management of large hepatocellular carcinoma in adult patients with Alagille syndrome: a case report and review of literature. Dig Dis Sci 2010, 55(11):3052-3058.
-
(2010)
Dig Dis Sci
, vol.55
, Issue.11
, pp. 3052-3058
-
-
Tsai, S.1
Gurakar, A.2
Anders, R.3
Lam-Himlin, D.4
Boitnott, J.5
Pawlik, T.M.6
-
46
-
-
84879073587
-
Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1
-
[PMID 23315998, in press]
-
Jeliazkova P., Jors S., Lee M., Zimber-Strobl U., Ferrer J., Schmid R.M., et al. Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1. Hepatology 2013, [PMID 23315998, in press].
-
(2013)
Hepatology
-
-
Jeliazkova, P.1
Jors, S.2
Lee, M.3
Zimber-Strobl, U.4
Ferrer, J.5
Schmid, R.M.6
-
47
-
-
70349230969
-
Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice
-
Tchorz J.S., Kinter J., Muller M., Tornillo L., Heim M.H., Bettler B. Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology 2009, 50(3):871-879.
-
(2009)
Hepatology
, vol.50
, Issue.3
, pp. 871-879
-
-
Tchorz, J.S.1
Kinter, J.2
Muller, M.3
Tornillo, L.4
Heim, M.H.5
Bettler, B.6
-
48
-
-
84869751765
-
Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice
-
[e1567]
-
Espanol-Suner R., Carpentier R., Van Hul N., Legry V., Achouri Y., Cordi S., et al. Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice. Gastroenterology 2012, 143(6):1564-1575. [e1567].
-
(2012)
Gastroenterology
, vol.143
, Issue.6
, pp. 1564-1575
-
-
Espanol-Suner, R.1
Carpentier, R.2
Van Hul, N.3
Legry, V.4
Achouri, Y.5
Cordi, S.6
-
49
-
-
84859609848
-
Neighborhood watch orchestrates liver regeneration
-
Diehl A.M. Neighborhood watch orchestrates liver regeneration. Nat Med 2012, 18(4):497-499.
-
(2012)
Nat Med
, vol.18
, Issue.4
, pp. 497-499
-
-
Diehl, A.M.1
-
50
-
-
78751585439
-
Hedgehog signaling in the liver
-
Omenetti A., Choi S., Michelotti G., Diehl A.M. Hedgehog signaling in the liver. J Hepatol 2011, 54(2):366-373.
-
(2011)
J Hepatol
, vol.54
, Issue.2
, pp. 366-373
-
-
Omenetti, A.1
Choi, S.2
Michelotti, G.3
Diehl, A.M.4
-
51
-
-
78649971678
-
Cholangiocarcinoma in Italy: a national survey on clinical characteristics, diagnostic modalities and treatment. Results from the "Cholangiocarcinoma" committee of the Italian Association for the Study of Liver disease
-
Alvaro D., Bragazzi M.C., Benedetti A., Fabris L., Fava G., Invernizzi P., et al. Cholangiocarcinoma in Italy: a national survey on clinical characteristics, diagnostic modalities and treatment. Results from the "Cholangiocarcinoma" committee of the Italian Association for the Study of Liver disease. Dig Liver Dis 2011, 43(1):60-65.
-
(2011)
Dig Liver Dis
, vol.43
, Issue.1
, pp. 60-65
-
-
Alvaro, D.1
Bragazzi, M.C.2
Benedetti, A.3
Fabris, L.4
Fava, G.5
Invernizzi, P.6
-
52
-
-
84862660912
-
Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma
-
Palmer W.C., Patel T. Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma. J Hepatol 2012, 57(1):69-76.
-
(2012)
J Hepatol
, vol.57
, Issue.1
, pp. 69-76
-
-
Palmer, W.C.1
Patel, T.2
-
53
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Lee J.S., Heo J., Libbrecht L., Chu I.S., Kaposi-Novak P., Calvisi D.F., et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006, 12(4):410-416.
-
(2006)
Nat Med
, vol.12
, Issue.4
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
Chu, I.S.4
Kaposi-Novak, P.5
Calvisi, D.F.6
-
54
-
-
84861534766
-
Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes
-
Komuta M., Govaere O., Vandecaveye V., Akiba J., Van Steenbergen W., Verslype C., et al. Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes. Hepatology 2012, 55(6):1876-1888.
-
(2012)
Hepatology
, vol.55
, Issue.6
, pp. 1876-1888
-
-
Komuta, M.1
Govaere, O.2
Vandecaveye, V.3
Akiba, J.4
Van Steenbergen, W.5
Verslype, C.6
-
55
-
-
84871191893
-
Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma
-
Chan I.S., Guy C.D., Chen Y., Lu J., Swiderska-Syn M., Michelotti G.A., et al. Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma. Cancer Res 2012, 72(24):6344-6350.
-
(2012)
Cancer Res
, vol.72
, Issue.24
, pp. 6344-6350
-
-
Chan, I.S.1
Guy, C.D.2
Chen, Y.3
Lu, J.4
Swiderska-Syn, M.5
Michelotti, G.A.6
-
56
-
-
80052420490
-
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer
-
Philips G.M., Chan I.S., Swiderska M., Schroder V.T., Guy C., Karaca G.F., et al. Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. PLoS One 2011, 6(9):e23943.
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Philips, G.M.1
Chan, I.S.2
Swiderska, M.3
Schroder, V.T.4
Guy, C.5
Karaca, G.F.6
-
57
-
-
84856527774
-
Oncogenic beta-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice
-
Anson M., Crain-Denoyelle A.M., Baud V., Chereau F., Gougelet A., Terris B., et al. Oncogenic beta-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice. J Clin Invest 2012, 122(2):586-599.
-
(2012)
J Clin Invest
, vol.122
, Issue.2
, pp. 586-599
-
-
Anson, M.1
Crain-Denoyelle, A.M.2
Baud, V.3
Chereau, F.4
Gougelet, A.5
Terris, B.6
-
58
-
-
73949099275
-
Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence
-
Zulehner G., Mikula M., Schneller D., van Zijl F., Huber H., Sieghart W., et al. Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. Am J Pathology 2010, 176(1):472-481.
-
(2010)
Am J Pathology
, vol.176
, Issue.1
, pp. 472-481
-
-
Zulehner, G.1
Mikula, M.2
Schneller, D.3
van Zijl, F.4
Huber, H.5
Sieghart, W.6
-
59
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen L.W., Bird J., West D.C., Soreng A.L., Reynolds T.C., Smith S.D., et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991, 66(4):649-661.
-
(1991)
Cell
, vol.66
, Issue.4
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
-
60
-
-
5044225888
-
Activating mutations of Notch1 in human T cell acute lymphoblastic leukemia
-
Weng A.P., Ferrando A.A., Lee W., Morris JPt, Silverman L.B., Sanchez-Irizarry C., et al. Activating mutations of Notch1 in human T cell acute lymphoblastic leukemia. Science 2004, 306(5694):269-271.
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.P.T.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
-
61
-
-
79955460636
-
Notch signalling in solid tumours: a little bit of everything but not all the time
-
Ranganathan P., Weaver K.L., Capobianco A.J. Notch signalling in solid tumours: a little bit of everything but not all the time. Nat Rev Cancer 2011, 11(5):338-351.
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.5
, pp. 338-351
-
-
Ranganathan, P.1
Weaver, K.L.2
Capobianco, A.J.3
-
62
-
-
14244266581
-
Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice
-
Croquelois A., Blindenbacher A., Terracciano L., Wang X., Langer I., Radtke F., et al. Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice. Hepatology 2005, 41(3):487-496.
-
(2005)
Hepatology
, vol.41
, Issue.3
, pp. 487-496
-
-
Croquelois, A.1
Blindenbacher, A.2
Terracciano, L.3
Wang, X.4
Langer, I.5
Radtke, F.6
-
63
-
-
0346365362
-
Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis
-
Qi R., An H., Yu Y., Zhang M., Liu S., Xu H., et al. Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res 2003, 63(23):8323-8329.
-
(2003)
Cancer Res
, vol.63
, Issue.23
, pp. 8323-8329
-
-
Qi, R.1
An, H.2
Yu, Y.3
Zhang, M.4
Liu, S.5
Xu, H.6
-
64
-
-
80555154065
-
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
-
Viatour P., Ehmer U., Saddic L.A., Dorrell C., Andersen J.B., Lin C., et al. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med 2011, 208(10):1963-1976.
-
(2011)
J Exp Med
, vol.208
, Issue.10
, pp. 1963-1976
-
-
Viatour, P.1
Ehmer, U.2
Saddic, L.A.3
Dorrell, C.4
Andersen, J.B.5
Lin, C.6
-
65
-
-
67650236862
-
Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression
-
Wang C., Qi R., Li N., Wang Z., An H., Zhang Q., et al. Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression. J Biol Chem 2009, 284(24):16183-16190.
-
(2009)
J Biol Chem
, vol.284
, Issue.24
, pp. 16183-16190
-
-
Wang, C.1
Qi, R.2
Li, N.3
Wang, Z.4
An, H.5
Zhang, Q.6
-
66
-
-
64549091858
-
Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism
-
Giovannini C., Gramantieri L., Chieco P., Minguzzi M., Lago F., Pianetti S., et al. Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism. J Hepatol 2009, 50(5):969-979.
-
(2009)
J Hepatol
, vol.50
, Issue.5
, pp. 969-979
-
-
Giovannini, C.1
Gramantieri, L.2
Chieco, P.3
Minguzzi, M.4
Lago, F.5
Pianetti, S.6
-
67
-
-
79953760895
-
Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma
-
Lim S.O., Park Y.M., Kim H.S., Quan X., Yoo J.E., Park Y.N., et al. Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma. Hepatology 2011, 53(4):1352-1362.
-
(2011)
Hepatology
, vol.53
, Issue.4
, pp. 1352-1362
-
-
Lim, S.O.1
Park, Y.M.2
Kim, H.S.3
Quan, X.4
Yoo, J.E.5
Park, Y.N.6
-
68
-
-
84856264859
-
IKKalpha activation of Notch links tumorigenesis via FOXA2 suppression
-
Liu M., Lee D.F., Chen C.T., Yen C.J., Li L.Y., Lee H.J., et al. IKKalpha activation of Notch links tumorigenesis via FOXA2 suppression. Mol Cell 2012, 45(2):171-184.
-
(2012)
Mol Cell
, vol.45
, Issue.2
, pp. 171-184
-
-
Liu, M.1
Lee, D.F.2
Chen, C.T.3
Yen, C.J.4
Li, L.Y.5
Lee, H.J.6
-
69
-
-
84865124257
-
Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma
-
Guo X., Xiong L., Sun T., Peng R., Zou L., Zhu H., et al. Expression features of SOX9 associate with tumor progression and poor prognosis of hepatocellular carcinoma. Diagn Pathol 2012, 7:44.
-
(2012)
Diagn Pathol
, vol.7
, pp. 44
-
-
Guo, X.1
Xiong, L.2
Sun, T.3
Peng, R.4
Zou, L.5
Zhu, H.6
-
70
-
-
19044383947
-
Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis
-
Ishimura N., Bronk S.F., Gores G.J. Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis. Gastroenterology 2005, 128(5):1354-1368.
-
(2005)
Gastroenterology
, vol.128
, Issue.5
, pp. 1354-1368
-
-
Ishimura, N.1
Bronk, S.F.2
Gores, G.J.3
-
71
-
-
79951902341
-
Intrahepatic cholangiocarcinoma: new insights in pathology
-
Sempoux C., Jibara G., Ward S.C., Fan C., Qin L., Roayaie S., et al. Intrahepatic cholangiocarcinoma: new insights in pathology. Semin Liver Dis 2011, 31(1):49-60.
-
(2011)
Semin Liver Dis
, vol.31
, Issue.1
, pp. 49-60
-
-
Sempoux, C.1
Jibara, G.2
Ward, S.C.3
Fan, C.4
Qin, L.5
Roayaie, S.6
-
72
-
-
84859418538
-
Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice
-
[e962]
-
Dill M.T., Rothweiler S., Djonov V., Hlushchuk R., Tornillo L., Terracciano L., et al. Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology 2011, 142(4):967-977. [e962].
-
(2011)
Gastroenterology
, vol.142
, Issue.4
, pp. 967-977
-
-
Dill, M.T.1
Rothweiler, S.2
Djonov, V.3
Hlushchuk, R.4
Tornillo, L.5
Terracciano, L.6
-
73
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es J.H., van Gijn M.E., Riccio O., van den Born M., Vooijs M., Begthel H., et al. Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 2005, 435(7044):959-963.
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 959-963
-
-
van Es, J.H.1
van Gijn, M.E.2
Riccio, O.3
van den Born, M.4
Vooijs, M.5
Begthel, H.6
-
74
-
-
76749157186
-
Chronic DLL4 blockade induces vascular neoplasms
-
Yan M., Callahan C.A., Beyer J.C., Allamneni K.P., Zhang G., Ridgway J.B., et al. Chronic DLL4 blockade induces vascular neoplasms. Nature 2010, 463(7282):E6-E7.
-
(2010)
Nature
, vol.463
, Issue.7282
-
-
Yan, M.1
Callahan, C.A.2
Beyer, J.C.3
Allamneni, K.P.4
Zhang, G.5
Ridgway, J.B.6
|