Living with advanced but stable multiple myeloma: A study of the symptom burden and cumulative effects of disease and intensive (hematopoietic stem cell transplant-based) treatment on health-related quality of life

Journal of Pain and Symptom Management

Volumn 46, Issue 5, 2013, Pages 671-680

  Boland, Elaine ^a   Eiser, Christine ^a   Ezaydi, Yousef ^b   Greenfield, Diana M ^c,d   Ahmedzai, Sam H ^a   Snowden, John A ^b,d  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c WESTON PARK HOSPITAL   (United Kingdom)

^d Late Effects Group   (United Kingdom)

Author keywords

fatigue; late effects; Multiple myeloma; neuropathy; pain; psychosocial; quality of life; symptom burden

Indexed keywords

ALPHA INTERFERON; BISPHOSPHONIC ACID DERIVATIVE; BORTEZOMIB; CODEINE; DEXAMETHASONE; DOXORUBICIN; FENTANYL; GABAPENTIN; INTERLEUKIN 6; LENALIDOMIDE; M PROTEIN; MELPHALAN; OXYCODONE; PREGABALIN; STEROID; THALIDOMIDE; TRAMADOL; TUMOR NECROSIS FACTOR ALPHA; VINCRISTINE;

ADULT; ADVANCED CANCER; AGED; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BRIEF PAIN INVENTORY SHORT FORM; CANCER COMBINATION CHEMOTHERAPY; CANCER FATIGUE; CANCER GROWTH; CANCER PAIN; CANCER PATIENT; CLINICAL ARTICLE; CONSTIPATION; CROSS-SECTIONAL STUDY; DIARRHEA; DRUG MEGADOSE; DYSPNEA; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; INDEPENDENCE; INDUCTION CHEMOTHERAPY; INSOMNIA; INTENSIVE CARE; LOSS OF APPETITE; MALE; MULTIMODALITY CANCER THERAPY; MULTIPLE MYELOMA; MULTIPLE MYELOMA MODULE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NAUSEA AND VOMITING; PAIN ASSESSMENT; PATIENT ASSESSMENT; PERIPHERAL NEUROPATHY; PROTEIN BLOOD LEVEL; QUALITY OF LIFE; QUALITY OF LIFE QUESTIONNAIRE CORE 30; SELF REPORT LEEDS ASSESSMENT OF NEUROPATHIC SYMPTOMS AND SIGN; SHORT FORM 12; STEROID THERAPY; SYMPTOM ASSESSMENT; TUMOR VOLUME; WORK DISABILITY;

FATIGUE; LATE EFFECTS; MULTIPLE MYELOMA; NEUROPATHY; PAIN; PSYCHOSOCIAL; QUALITY OF LIFE; SYMPTOM BURDEN;

ADULT; AGED; COMORBIDITY; FEMALE; GREAT BRITAIN; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIPLE MYELOMA; NEURALGIA; PREVALENCE; QUALITY OF LIFE; RISK FACTORS; SURVIVAL RATE; SURVIVORS; SYMPTOM ASSESSMENT;

EID: 84886950454     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2012.11.003     Document Type: Article

References (41)

1. S.K. Kumar, S.V. Rajkumar, and A. Dispenzieri Improved survival in multiple myeloma and the impact of novel therapies Blood 111 2008 2516 2520
2. D. Pulte, A. Gondos, and H. Brenner Improvement in survival of older adults with multiple myeloma: results of an updated period analysis of SEER data Oncologist 16 2011 1600 1603
3. A.T. Johnsen, D. Tholstrup, M.A. Petersen, L. Pedersen, and M. Groenvold Health-related quality of life in a nationally representative sample of haematological patients Eur J Haematol 83 2009 139 148
4. J.M. Bird, R.G. Owen, and S. D'Sa Guidelines for the diagnosis and management of multiple myeloma 2011 Br J Haematol 154 2011 32 75
5. H. Brenner, A. Gondos, and D. Pulte Expected long-term survival of patients diagnosed with multiple myeloma in 2006-2010 Haematologica 94 2009 270 275
6. J.A. Snowden, S.H. Ahmedzai, and J. Ashcroft Guidelines for supportive care in multiple myeloma 2011 Br J Haematol 154 2011 76 103
7. A.C. Sherman, S. Simonton, U. Latif, R. Spohn, and G. Tricot Psychosocial adjustment and quality of life among multiple myeloma patients undergoing evaluation for autologous stem cell transplantation Bone Marrow Transplant 33 2004 955 962
8. J. Larsen, G. Nordstrom, B. Bjorkstrand, P. Ljungman, and A. Gardulf Symptom distress, functional status and health-related quality of life before high-dose chemotherapy with stem-cell transplantation Eur J Cancer Care (Engl) 12 2003 71 80
9. D.J. Straus, M.A. Testa, and B.J. Sarokhan Quality-of-life and health benefits of early treatment of mild anemia: a randomized trial of epoetin alfa in patients receiving chemotherapy for hematologic malignancies Cancer 107 2006 1909 1917
10. N. Gulbrandsen, M.J. Hjermstad, and F. Wisloff Interpretation of quality of life scores in multiple myeloma by comparison with a reference population and assessment of the clinical importance of score differences Eur J Haematol 72 2004 172 180
11. A. Molassiotis, B. Wilson, S. Blair, T. Howe, and J. Cavet Living with multiple myeloma: experiences of patients and their informal caregivers Support Care Cancer 19 2011 101 111
12. U. Frodin, S. Borjeson, J. Lyth, and K. Lotfi A prospective evaluation of patients' health-related quality of life during auto-SCT: a 3-year follow-up Bone Marrow Transplant 46 2011 1345 1352
13. F. Mols, A.J.J.M. Vingerhoets, J.W. Coebergh, and L.V. van de Poll-Franse Quality of life among long-term breast cancer survivors: a systematic review Eur J Cancer 41 2005 2613 2619
14. A. Collado-Hidalgo, J.E. Bower, P.A. Ganz, S.W. Cole, and M.R. Irwin Inflammatory biomarkers for persistent fatigue in breast cancer survivors Clin Cancer Res 12 2006 2759 2766
15. R.H. Osborne, G. Hawthorne, E.A. Lew, and L.C. Gray Quality of life assessment in the community-dwelling elderly: validation of the Assessment of Quality of Life (AQoL) Instrument and comparison with the SF-36 J Clin Epidemiol 56 2003 138 147
16. J.E.J. Ware, M. Kosinski, and S.D. Keller A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity Med Care 34 1996 220 233
17. N.K. Aaronson, S. Ahmedzai, and B. Bergman The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology J Natl Cancer Inst 85 1993 365 376
18. K. Cocks, D. Cohen, and F. Wisloff An international field study of the reliability and validity of a disease-specific questionnaire module (the QLQ-MY20) in assessing the quality of life of patients with multiple myeloma Eur J Cancer 43 2007 1670 1678
19. C. Jenkinson, R. Layte, and D. Jenkinson A shorter form health survey: can the SF-12 replicate results from the SF-36 in longitudinal studies? J Public Health Med 19 1997 179 186
20. S.B. Detmar, M.J. Muller, J.H. Schornagel, L.D. Wever, and N.K. Aaronson Health-related quality-of-life assessments and patient-physician communication: a randomized controlled trial JAMA 288 2002 3027 3034
21. P.M. Fayers, N.K. Aaronson, and K. Bjordal EORTC QLQ-C30 scoring manual 3rd ed. 2001 EORTC Quality of Life Group Brussels
22. S.M. Spencer, J.M. Lehman, and C. Wynings Concerns about breast cancer and relations to psychosocial well-being in a multiethnic sample of early-stage patients Health Psychol 18 1999 159 168
23. C.S. Cleeland, and K.M. Ryan Pain assessment: global use of the Brief Pain Inventory Ann Acad Med Singapore 23 1994 129 138
24. M.I. Bennett, B.H. Smith, N. Torrance, and J. Potter The S-LANSS score for identifying pain of predominantly neuropathic origin: validation for use in clinical and postal research J Pain 6 2005 149 158
25. SPSS PASW statistics 18.0 2009 SPSS, Inc. Chicago
26. S.J. Walters Quality of life outcomes in clinical trials and health-care evaluation: A practical guide to analysis and interpretation 2009 John Wiley & Sons, Ltd. Chichester, UK
27. M.J. Campbell, S.J. Walters, and D. Machin Medical statistics: A textbook for the health sciences 2007 John Wiley & Sons, Ltd. Chichester, UK
28. T.D.V. Swinscow, and M.J. Campbell Statistics at square one 2002 BMJ Books London, UK
29. C. Jenkinson, and R. Layte Development and testing of the UK SF-12 (short form health survey) J Health Serv Res Policy 2 1997 14 18
30. P.G. Richardson, M. Delforge, and M. Beksac Management of treatment-emergent peripheral neuropathy in multiple myeloma Leukemia 26 2012 595 608
31. A. Molassiotis, B. Wilson, S. Blair, T. Howe, and J. Cavet Unmet supportive care needs, psychological well-being and quality of life in patients living with multiple myeloma and their partners Psychooncology 20 2011 88 97
32. J. Pidala, C. Anasetti, and H. Jim Health-related quality of life following haematopoietic cell transplantation: patient education, evaluation and intervention Br J Haematol 148 2010 373 385
33. V.M. Lauta Interleukin-6 and the network of several cytokines in multiple myeloma: an overview of clinical and experimental data Cytokine 16 2001 79 86
34. W.A. Verri Jr., T.M. Cunha, and C.A. Parada Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacol Ther 112 2006 116 138
35. G. Velikova, N. Awad, and R. Coles-Gale The clinical value of quality of life assessment in oncology practice-a qualitative study of patient and physician views Psychooncology 17 2008 690 698
36. M.G. Hendriks, and H.C. Schouten Quality of life after stem cell transplantation: a patient, partner and physician perspective Eur J Intern Med 13 2002 52 56
37. J.C. van der Wouden, J.G. Greaves-Otte, and J. Greaves Occupational reintegration of long-term cancer survivors J Occup Med 34 1992 1084 1089
38. S.H. Ahmedzai, and D. Walsh Palliative medicine and modern cancer care Semin Oncol 27 2000 1 6
39. M. Kraj, R. Poglod, U. Sokolowska, B. Kruk, and E. Czajkowska Long, even exceeding 20 years, survival in multiple myeloma [abstract] Haematologica 95 Suppl 2 2010 abs. 0951
40. A.K. Kvam, P. Fayers, M. Hjermstad, N. Gulbrandsen, and F. Wisloff Health-related quality of life assessment in randomised controlled trials in multiple myeloma: a critical review of methodology and impact on treatment recommendations Eur J Haematol 83 2009 279 289
41. N. Ahmed, J.C. Bestall, S.A. Payne, B. Noble, and S.H. Ahmedzai The use of cognitive interviewing methodology in the design and testing of a screening tool for supportive and palliative care needs Support Care Cancer 17 2009 665 673