-
1
-
-
0032585605
-
The 16,17-double bond is needed for irreversible inhibition of human cytochrome p45017alpha by abiraterone (17-(3-pyridyl)androsta-5, 16-dien-3beta-ol) and related steroidal inhibitors
-
M. Jarman, S.E. Barrie, and J.M. Llera The 16,17-double bond is needed for irreversible inhibition of human cytochrome p45017alpha by abiraterone (17-(3-pyridyl)androsta-5, 16-dien-3beta-ol) and related steroidal inhibitors J Med Chem 41 1998 5375 5381
-
(1998)
J Med Chem
, vol.41
, pp. 5375-5381
-
-
Jarman, M.1
Barrie, S.E.2
Llera, J.M.3
-
2
-
-
68949094223
-
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
G. Attard, A.H. Reid, and R. A'Hern Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer J Clin Oncol 27 2009 3742 3748
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
-
3
-
-
77951518711
-
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
-
A.H. Reid, G. Attard, and D.C. Danila Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate J Clin Oncol 28 2010 1489 1495
-
(2010)
J Clin Oncol
, vol.28
, pp. 1489-1495
-
-
Reid, A.H.1
Attard, G.2
Danila, D.C.3
-
4
-
-
77951591066
-
Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer
-
D.C. Danila, M.J. Morris, and J.S. de Bono Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer J Clin Oncol 28 2010 1496 1501
-
(2010)
J Clin Oncol
, vol.28
, pp. 1496-1501
-
-
Danila, D.C.1
Morris, M.J.2
De Bono, J.S.3
-
5
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
J.S. de Bono, C.J. Logothetis, and A. Molina Abiraterone and increased survival in metastatic prostate cancer N Engl J Med 364 2011 1995 2005
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
6
-
-
84866948935
-
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: Final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
-
K. Fizazi, H.I. Scher, and A. Molina Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study Lancet Oncol 13 2012 983 992
-
(2012)
Lancet Oncol
, vol.13
, pp. 983-992
-
-
Fizazi, K.1
Scher, H.I.2
Molina, A.3
-
7
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
J.S. de Bono, S. Oudard, and M. Ozguroglu Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial Lancet 376 2010 1147 1154
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
8
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
H.I. Scher, K. Fizazi, and F. Saad Increased survival with enzalutamide in prostate cancer after chemotherapy N Engl J Med 367 2012 1187 1197
-
(2012)
N Engl J Med
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
9
-
-
84866847135
-
Abiraterone acetate withdrawal syndrome: Does it exist?
-
H. Gauthier, G. Bousquet, and D. Pouessel Abiraterone acetate withdrawal syndrome: does it exist? Case Rep Oncol 5 2012 385 387
-
(2012)
Case Rep Oncol
, vol.5
, pp. 385-387
-
-
Gauthier, H.1
Bousquet, G.2
Pouessel, D.3
-
10
-
-
84886953295
-
Is there a withdrawal syndrome with abiraterone acetate (AA)?
-
Abstract 89
-
L. Albiges, E. Auclin, and B. Rousseau Is there a withdrawal syndrome with abiraterone acetate (AA)? J Clin Oncol 31 2013 Abstract 89
-
(2013)
J Clin Oncol
, vol.31
-
-
Albiges, L.1
Auclin, E.2
Rousseau, B.3
-
11
-
-
0033764970
-
Antiandrogen withdrawal syndrome associated with prostate cancer therapies: Incidence and clinical significance
-
R. Paul, and J. Breul Antiandrogen withdrawal syndrome associated with prostate cancer therapies: incidence and clinical significance Drug Saf 23 2000 381 390
-
(2000)
Drug Saf
, vol.23
, pp. 381-390
-
-
Paul, R.1
Breul, J.2
-
12
-
-
41949104346
-
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
-
H.I. Scher, S. Halabi, and I. Tannock Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group J Clin Oncol 26 2008 1148 1159
-
(2008)
J Clin Oncol
, vol.26
, pp. 1148-1159
-
-
Scher, H.I.1
Halabi, S.2
Tannock, I.3
-
13
-
-
66149139452
-
From RECIST to PERCIST: Evolving considerations for PET response criteria in solid tumors
-
R.L. Wahl, H. Jacene, and Y. Kasamon From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors J Nucl Med 50 suppl 1 2009 122S 150S
-
(2009)
J Nucl Med
, vol.50
, Issue.SUPPL. 1
-
-
Wahl, R.L.1
Jacene, H.2
Kasamon, Y.3
-
14
-
-
0029011116
-
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
-
M.E. Taplin, G.J. Bubley, and T.D. Shuster Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer N Engl J Med 332 1995 1393 1398
-
(1995)
N Engl J Med
, vol.332
, pp. 1393-1398
-
-
Taplin, M.E.1
Bubley, G.J.2
Shuster, T.D.3
-
15
-
-
79952253824
-
EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer
-
N. Mottet, J. Bellmunt, and M. Bolla EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer Eur Urol 59 2011 572 583
-
(2011)
Eur Urol
, vol.59
, pp. 572-583
-
-
Mottet, N.1
Bellmunt, J.2
Bolla, M.3
-
16
-
-
0031001274
-
Prostate specific antigen decreases after withdrawal of antiandrogen therapy with bicalutamide or flutamide in patients receiving combined androgen blockade
-
P.F. Schellhammer, P. Venner, and G.P. Haas Prostate specific antigen decreases after withdrawal of antiandrogen therapy with bicalutamide or flutamide in patients receiving combined androgen blockade J Urol 157 1997 1731 1735
-
(1997)
J Urol
, vol.157
, pp. 1731-1735
-
-
Schellhammer, P.F.1
Venner, P.2
Haas, G.P.3
-
17
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
E.A. Eisenhauer, P. Therasse, and J. Bogaerts New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1) Eur J Cancer 45 2009 228 247
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
-
18
-
-
1842471816
-
Molecular basis for the antiandrogen withdrawal syndrome
-
H. Miyamoto, M.M. Rahman, and C. Chang Molecular basis for the antiandrogen withdrawal syndrome J Cell Biochem 91 2004 3 12
-
(2004)
J Cell Biochem
, vol.91
, pp. 3-12
-
-
Miyamoto, H.1
Rahman, M.M.2
Chang, C.3
-
19
-
-
80054021222
-
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors
-
C. Cai, S. Chen, and P. Ng Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors Cancer Res 71 2011 6503 6513
-
(2011)
Cancer Res
, vol.71
, pp. 6503-6513
-
-
Cai, C.1
Chen, S.2
Ng, P.3
-
20
-
-
80052827038
-
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
-
E.A. Mostaghel, B.T. Marck, and S.R. Plymate Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants Clin Cancer Res 17 2011 5913 5925
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5913-5925
-
-
Mostaghel, E.A.1
Marck, B.T.2
Plymate, S.R.3
-
21
-
-
84863393126
-
Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone
-
E. Efstathiou, M. Titus, and D. Tsavachidou Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone J Clin Oncol 30 2012 637 643
-
(2012)
J Clin Oncol
, vol.30
, pp. 637-643
-
-
Efstathiou, E.1
Titus, M.2
Tsavachidou, D.3
-
22
-
-
0028858232
-
Antiandrogen withdrawal syndrome in prostate cancer after treatment with steroidal antiandrogen chlormadinone acetate
-
K. Akakura, S. Akimoto, and T. Ohki Antiandrogen withdrawal syndrome in prostate cancer after treatment with steroidal antiandrogen chlormadinone acetate Urology 45 1995 700 704
-
(1995)
Urology
, vol.45
, pp. 700-704
-
-
Akakura, K.1
Akimoto, S.2
Ohki, T.3
-
23
-
-
0029027627
-
Complete remission of hormone refractory adenocarcinoma of the prostate in response to withdrawal of diethylstilbestrol
-
N.K. Bissada, and A.T. Kaczmarek Complete remission of hormone refractory adenocarcinoma of the prostate in response to withdrawal of diethylstilbestrol J Urol 153 1995 1944 1945
-
(1995)
J Urol
, vol.153
, pp. 1944-1945
-
-
Bissada, N.K.1
Kaczmarek, A.T.2
-
24
-
-
0029007052
-
Dramatic prostate specific antigen decrease in response to discontinuation of megestrol acetate in advanced prostate cancer: Expansion of the antiandrogen withdrawal syndrome
-
N.A. Dawson, and D.G. McLeod Dramatic prostate specific antigen decrease in response to discontinuation of megestrol acetate in advanced prostate cancer: expansion of the antiandrogen withdrawal syndrome J Urol 153 1995 1946 1947
-
(1995)
J Urol
, vol.153
, pp. 1946-1947
-
-
Dawson, N.A.1
McLeod, D.G.2
-
25
-
-
0032400811
-
Antiandrogen withdrawal syndrome with cyproterone acetate
-
A. Sella, D. Flex, and A. Sulkes Antiandrogen withdrawal syndrome with cyproterone acetate Urology 52 1998 1091 1093
-
(1998)
Urology
, vol.52
, pp. 1091-1093
-
-
Sella, A.1
Flex, D.2
Sulkes, A.3
-
26
-
-
0034125195
-
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor
-
X.Y. Zhao, P.J. Malloy, and A.V. Krishnan Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor Nat Med 6 2000 703 706
-
(2000)
Nat Med
, vol.6
, pp. 703-706
-
-
Zhao, X.Y.1
Malloy, P.J.2
Krishnan, A.V.3
-
27
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
C.J. Ryan, M.R. Smith, and J.S. de Bono Abiraterone in metastatic prostate cancer without previous chemotherapy N Engl J Med 368 2013 138 148
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
|